1. Prescripción de antibióticos en pacientes hospitalizados con COVID-19 en un hospital privado de Caracas: Estudio retrospectivo.
- Author
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Silva, Isabel-Carlota, Guzmán, Manuel, de Oca, María Montes, Bacci, Santiago, de Abreu, Fátima, Villarroel, Héctor, Stulin, Irene, Blanco, Gabriela, Sánchez, Laura, Quevedo, Jennireth, Arvelo, María Cristina, Valera, Nathalia, Papa, Irene, Carlos Catari, Juan, Luis Lopez, José, Moran, Brigitte, Cárdenas, Claudio, Santucci, Saverio, Luis Viloria, José, and García, Eleonora
- Subjects
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COVID-19 , *HOSPITAL patients , *BACTERIAL cultures , *PATHOGENIC bacteria , *MIXED infections , *INTENSIVE care units , *HOSPITALS - Abstract
Background: There is little information on the prevalence of bacterial coinfection and use of antibiotics in hospitalized COVID-19 patients. The present study assesses the frequency of in-hospital antibiotic prescription, the bacterial cultures implementation and the clinical characteristics of patients with COVID-19 according to the use of antibiotics. Methods: Retrospective, observational study of hospitalized patients with COVID-19. The ISARIC-WHO form was used for data collection. Results: 145 patients were included, 95 men and 50 women, with a mean age 63.8±16.0 years. 79/145 (54.5%) patients received antibiotics, 52/145 (35%) had samples for culture and 49/145 (33.8%) were blood cultures. Pathogenic bacteria were isolated only in 7% of the patients. The patients with antibiotics had worse oxygenation, chest tomography and inflammatory markers, more admission to ICU, deaths, and prolonged hospital stay. Conclusion: Our results do not support the initial widespread use of antibiotics in hospitalized COVID-19 patients without knowing the pathogen and its susceptibility. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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