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Your search keyword '"Ahmed Alaa Abdul-Aziz"' showing total 2 results
Start Over Author "Ahmed Alaa Abdul-Aziz" Topic insulin resistance
2 results on '"Ahmed Alaa Abdul-Aziz"'

1. Asprosin in nonalcoholic fatty liver disease and hypothyroidism: a case-control study

Author

Mona Abdel-Latif Aboul-Seoud, Mohamed Kamal Ghitany, Ola Atef Sharaki, Ahmed Alaa Abdul-Aziz, and Mohammed Said Sayed Shater

Subjects
NAFLD, hypothyroidism, asprosin, insulin resistance, Medicine
Abstract

Purpose The present study aimed to determine the serum level of asprosin, a novel glucogenic and orexigenic hormone, in NAFLD and hypothyroidism patients.Methods This is a case–control study that included three groups of age and sex-matched subjects: hypothyroid patients with NAFLD (n = 26), hypothyroid patients without NAFLD (n = 25) and normal control subjects (n = 27). A detailed clinical history was obtained, and an examination was performed. Laboratory tests included fasting plasma glucose and insulin, lipid profile, TSH, free T4, AST, ALT, albumin, and asprosin. The homeostatic model assessment of insulin resistance (HOMA-IR) score was calculated. Abdominal ultrasonography was performed to calculate the hepatorenal index and define participants with NAFLD. The data were statistically analyzed.Results There was a statistically significant difference between the three groups regarding serum asprosin concentration (p

Published
2024
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2. DObesity: Relationship between vitamin D deficiency, obesity and sclerostin as a novel biomarker of bone metabolism

Author

Doreen N. Younan, Eman Z. Azzam, Mohamed Nabil Ata, Tarek Salem, and Ahmed Alaa Abdul-Aziz

Subjects
medicine.medical_specialty, Sclerostin, Bone metabolism, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Overweight, lcsh:Diseases of the endocrine glands. Clinical endocrinology, vitamin D deficiency, Bone remodeling, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Insulin resistance, Internal medicine, medicine, Vitamin D and neurology, 030212 general & internal medicine, Obesity, Vitamin D, lcsh:RC648-665, business.industry, medicine.disease, chemistry, Biomarker (medicine), medicine.symptom, business, Research Paper
Abstract

Aim: To study the relationship between obesity, insulin resistance, vitamin D deficiency and sclerostin as a bone biomarker. Materials and methods: Cross-section study of 75 subjects grouped into 3 groups; obese (n = 31), overweight (n = 23) and normal (n = 21) subjects. Sclerostin, fasting insulin, fasting plasma glucose and 25(OH)D were measured and anthropometric measures were taken. Results: 25(OH)D was lower in obese subjects than overweight and control groups (mean ± SD 5.27 ± 5.14 vs. 12.55 ± 6.99 vs.17.65 ± 4.07 ng/L, p

Published
2019

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