1. Insulin therapy in type 2 diabetes.
- Author
-
Davis T and Edelman SV
- Subjects
- Age Distribution, Aged, Blood Glucose drug effects, Diabetes Mellitus, Type 2 epidemiology, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Glucose Tolerance Test, Humans, Incidence, Injections, Subcutaneous, Insulin Infusion Systems, Male, Middle Aged, Prognosis, Risk Assessment, Severity of Illness Index, Sex Distribution, Treatment Outcome, Diabetes Mellitus, Type 2 diagnosis, Diabetes Mellitus, Type 2 drug therapy, Insulin administration & dosage
- Abstract
Unlike type 1 diabetic patients, who have no significant insulin secretion and require insulin therapy from the disease onset, a prominent feature in the early stages of type 2 diabetes is insulin resistance with hyperinsulinemia. Therefore, improving insulin sensitivity by diet, exercise, and weight management will benefit type 2 diabetic patients. When these measures fail, glycemic goals may be achieved with oral agents. However, at the late stage of disease,most patients require exogenous insulin therapy to achieve optimal glucose control. The American Diabetes Association recommends that the objective of normalizing glycemia and glycosylated hemoglobin concentrations for patients with type 2 diabetes should be similar to that for type 1 diabetes.
- Published
- 2004
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