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Background and Objectives: The recent approval of influenza A H1N1 monovalent vaccine has attracted considerable public health interest. The aim of this paper is to assess the development of vaccination campaign in Castilla y Leon., Material and Method: We have performed a descriptive analysis of the number of vaccines given in Castilla y Leon from November 16, 2009 to January 17, 2010, inside the designed campaign for that purpose., Results: The total number of vaccines administered has been 116,243, 86,810 of which were from Focetria(®) which were administered to 3286 children under 18 years; 28,439 were from Pandemrix(®) and 994 from Panenza(®). The estimated vaccination coverage for all of the target groups has reached a percentage of 26.3% while the coverage achieved in pregnant women has been 4.7%. Of all the vaccines administered during this period, 82.2% were applied in the first month of the vaccination campaign., Conclusion: The introduction of pandemic vaccine in target groups of Castilla y Leon has been lower than expected, with a mismatch between the different health areas., (Copyright © 2010 Elsevier España, S.L. All rights reserved.)

Background: In April 2009, the World Health Organization declared the emergence of human cases by a new influenza virus H1N1 as a Public Health Emergency of International Importance. Our objective was to analyze the characteristics of the cases investigated and to assess the compliance of the subjects studied with the indications and recommendations of the Health Regional Ministry of Health Castilla y León., Methods: A descriptive epidemiological study of all positive cases and every requests made to Castilla y León, from epidemiological weeks 44 to 50, both included., Results: 588 requests were made to test for influenza A H1N1 (58% males). The mean age was 34.8 years (27.1% between 15 and 44 years). 42% fulfilled criteria for severity. Chronic respiratory disease was the most common risk factor found (18.9%). Antiviral treatment was found in 19.1% (54.5% within the first 48 hours). 27.4% of the requests were positive (53.4% males). The mean age of the positive cases was 34.52 years was positive (33.1% between 15 and 44 years). 47.8% of them fulfilled criteria for severity and chronic respiratory disease was also the most common risk factor found also in the positive (26.7%). Only 6.8% were morbidly obese. 28.9% of positives received antiviral treatment (61.4% within the first 48 hours)., Conclusion: Most cases did not fulfil severity criteria, which illustrates the low compliance of monitoring protocols in sanitary care system.