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texto completo: acesso restrito. p. 46–51. Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-02-25T01:40:52Z No. of bitstreams: 1 nps7E.tmp.pdf: 193766 bytes, checksum: f8c9c31035e1570e5a9457efcc8dadd5 (MD5) Made available in DSpace on 2012-02-25T01:40:52Z (GMT). No. of bitstreams: 1 nps7E.tmp.pdf: 193766 bytes, checksum: f8c9c31035e1570e5a9457efcc8dadd5 (MD5) Previous issue date: 2011 Toxocara canis is a highly prevalent worldwide canine nematode responsible for enzootic and zoonotic infections. It is considered to be one of the main agents of human visceral and ocular larva migrans. False negative diagnosis may occur because adult infected dogs with “dormant” larvae may have negative fecal test results since they usually do not shed parasite eggs in their stools. During pregnancy, the larvae become active and infect the offspring through the placenta. A serological test can distinguish infected animals, thus increasing the accuracy of the diagnosis for epidemiological studies and prophylactic purposes. In the present work a serological investigation was carried out to study the risk factors for the acquisition of this infection in 301 dogs inhabiting the city of Salvador, northeast Brazil. A validated questionnaire was applied to the donors and caretakers to assess animal management practices. All dogs were submitted to clinical evaluation and blood collection. Serum samples were analyzed for IgG antibodies against excretory–secretory products of T. canis larvae, used as antigens, by indirect ELISA. The overall seroprevalence of antiT. canis IgG antibodies was 82.7%. Risk factors for T. canis infection included sex, area of origin within the city, homemade leftover food intake, failure to receive regular vaccination against infectious diseases and lack of preventive antihelminthic treatment. Most of these risk factors suggest a lack of veterinary care and poverty. The high frequency of seropositivity found for toxocariasis in dogs suggests that results based on parasitological fecal examination could underestimate the actual prevalence of the infection.