1. Resuscitation, survival and morbidity of extremely preterm infants in California 2011-2019.
- Author
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Higgins BV, Baer RJ, Steurer MA, Karvonen KL, Oltman SP, Jelliffe-Pawlowski LL, and Rogers EE
- Subjects
- Infant, Female, Infant, Newborn, Humans, Infant, Extremely Premature, Retrospective Studies, Gestational Age, Resuscitation, Morbidity, Infant Mortality, Infant, Premature, Diseases epidemiology, Infant, Premature, Diseases therapy, Premature Birth
- Abstract
Objective: To describe changes over time in resuscitation, survival, and morbidity of extremely preterm infants in California., Study Design: This population-based, retrospective cohort study includes infants born ≤28 weeks. Linked birth certificates and hospital discharge records were used to evaluate active resuscitation, survival, and morbidity across two epochs (2011-2014, 2015-2019)., Results: Of liveborn infants, 0.6% were born ≤28 weeks. Active resuscitation increased from 16.9% of 22-week infants to 98.1% of 25-week infants and increased over time in 22-, 23-, and 25-week infants (p-value ≤ 0.01). Among resuscitated infants, survival to discharge increased from 33.2% at 22 weeks to 96.1% at 28 weeks. Survival without major morbidity improved over time for 28-week infants (p-value < 0.01)., Conclusion: Among infants ≤28 weeks, resuscitation and survival increased with gestational age and morbidity decreased. Over time, active resuscitation of periviable infants and morbidity-free survival of 28-week infants increased. These trends may inform counseling around extremely preterm birth., (© 2023. The Author(s).)
- Published
- 2024
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