Search

Objectives: To identify the prevalence of viral congenital infections in newborns classified as premature, low-birthweight, small for gestational age or intrauterine growth restriction., Methods: The definition considered for selecting papers were: P as newborns younger than 28 days; V as low-birthweight, prematurity and intrauterine growth restriction; O as frequency of congenital infections with Cytomegalovirus, Parvovirus B19, Herpes Simplex, and Zika virus. The research was performed using EMBASE, LILACS, SCOPUS and MEDLINE databases, with no limitations on date and language., Results: Eight studies were included. Manuscripts including Herpes Simplex, Zika virus or Parvovirus B19 did not fulfill the defined criteria. A wide variation in the frequency of CMV congenital infection (0-4.8%) was found, which might be attributed to regional and methodological differences between investigations., Conclusions: Newborn characteristics associated with CMV congenital infections may direct investigations towards these patients with a higher probability of infection. However, as data are controversial, studies concerning screening of infection are important to define recommendations of diagnosis., (© 2022 Walter de Gruyter GmbH, Berlin/Boston.)

This study aimed to identify the maternal, labour and newborn risk factors associated with an Apgar score of ≤3 in the first minute of life. This was a cross-sectional evaluation from an internal database information system in a tertiary referral obstetric and neonatal centre. Newborns with gestational age ≥24 weeks and birth weight ≥500 g with a registered Apgar score in the first minute of life were included. A total of 4475 newborns had an Apgar score >3 and 154 newborns had an Apgar score ≤3 in the first minute of life. A multivariate analysis revealed that eclampsia (OR = 31.53), twin pregnancy (OR = 7.06), analgesia (OR = 1.97), prematurity (OR = 2.00) and caesarean section (OR = 2.06) were risk factors for an Apgar score ≤3 in the first minute of life. Identification of these risk factors indicates prompt assistance during prenatal and labour care to prevent neonatal hypoxia and low Apgar scores, identifying newborns that may need resuscitation procedures.Impact Statement What is already known on this subject? Adequate prenatal care and proper labour management are the main factors that reduce the risk of complications at birth. The Apgar score at the first minute of life reflects conditions during labour but it is not a parameter that indicates resuscitation procedures. Previous studies have reported the association Apgar score at five minutes of life with the neonatal outcome. What the results of this study add? This study identifies risk factors associated with an Apgar score ≤3 in the first minute of life in a tertiary referral hospital. Eclampsia was the greatest independent risk factor, increasing by 31 times the risk of having an Apgar score ≤3 in the first minute of life. What the implications are of these findings for clinical practice and/or further research? Identification of these risk factors, especially prompt treatment antenataly and during labour for hypertensive pregnant women, can prevent neonatal hypoxia and reduce the number of newborns that may need resuscitation procedures.