Search

Your search keyword '"Caoci S"' showing total 2 results
Start Over Author "Caoci S" Topic infant, newborn, diseases
2 results on '"Caoci S"'

1. Inhibitors of gastric acid secretion drugs increase neonatal morbidity and mortality.

Author

Terrin G, Canani RB, Passariello A, Caoci S, and De Curtis M

Subjects
Adult, Drug-Related Side Effects and Adverse Reactions epidemiology, Drug-Related Side Effects and Adverse Reactions mortality, Enterocolitis, Necrotizing drug therapy, Enterocolitis, Necrotizing epidemiology, Enterocolitis, Necrotizing mortality, Gastric Acid metabolism, Humans, Infant Mortality, Infant, Newborn, Infant, Newborn, Diseases drug therapy, Infections congenital, Infections drug therapy, Infections epidemiology, Infections mortality, Morbidity, Gastrointestinal Agents adverse effects, Gastrointestinal Agents therapeutic use, Infant, Newborn, Diseases epidemiology, Infant, Newborn, Diseases mortality
Abstract

Aims: To analyze all evidence on the possible increase in morbidity and mortality determined by the use of inhibitors of gastric acid secretion (IGAS) drugs., Materials and Methods: We review all evidence exploring the adverse events associated with IGAS use in neonates., Results: Despite being prescribed in an off-label manner because of the perceived safety and potential benefit demonstrated for older populations, IGAS are being increasingly used in the neonatal period with much evidence derived from adults and children. Few data are available for neonates and indicate an association between IGAS use with infections and necrotizing enterocolitis (NEC), and with an increased mortality. Delayed gastric emptying, increased gastric mucus viscosity, modification in microbiota, and impairment of neutrophils functions are possible mechanisms of adverse events associated with IGAS use., Conclusions: A careful prescription of IGAS is crucial in order to reduce iatrogenic damage in neonates.

Published
2012
Full Text
View/download PDF

2. Inhibitors of gastric acid secretion drugs increase neonatal morbidity and mortality

Author

Terrin G, Passariello A, Caoci S, De Curtis M., PASSARIELLO, ANNALISA, BERNI CANANI, ROBERTO, Terrin, G, BERNI CANANI, Roberto, Passariello, A, Caoci, S, De Curtis, M., and Passariello, Annalisa

Subjects
Adult, medicine.medical_specialty, neonatal sepsis, Drug-Related Side Effects and Adverse Reactions, diarrhea, very low birth weight, Infections, Infant, Newborn, Diseases, Gastric Acid, Ranitidine, ranitidine, Gastrointestinal Agents, Enterocolitis, Necrotizing, Internal medicine, Infant Mortality, medicine, Humans, histamine-2-receptor antagonists, clostridium difficile, necrotizing enterocolitis, neonates, proton pump inhibitors, Intensive care medicine, Adverse effect, Neonatal sepsis, Gastric emptying, business.industry, Infant, Newborn, Obstetrics and Gynecology, Clostridium difficile, medicine.disease, Diarrhea, Pediatrics, Perinatology and Child Health, Necrotizing enterocolitis, Gastric acid, Morbidity, medicine.symptom, business, medicine.drug
Abstract

Aims: To analyze all evidence on the possible increase in morbidity and mortality determined by the use of inhibitors of gastric acid secretion (IGAS) drugs. Materials and Methods: We review all evidence exploring the adverse events associated with IGAS use in neonates. Results: Despite being prescribed in an off-label manner because of the perceived safety and potential benefit demonstrated for older populations, IGAS are being increasingly used in the neonatal period with much evidence derived from adults and children. Few data are available for neonates and indicate an association between IGAS use with infections and necrotizing enterocolitis (NEC), and with an increased mortality. Delayed gastric emptying, increased gastric mucus viscosity, modification in microbiota, and impairment of neutrophils functions are possible mechanisms of adverse events associated with IGAS use. Conclusions: A careful prescription of IGAS is crucial in order to reduce iatrogenic damage in neonates.

Catalog

Books, media, physical & digital resources
See catalog results