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2 results on '"Vinciane Vlieghe"'

1. Belgian Consensus Recommendations to Prevent Vitamin K Deficiency Bleeding in the Term and Preterm Infant

Author

Isabel George, Yvan Vandenplas, Pierre Philippet, Luc Cornette, Vinciane Vlieghe, Elisabeth Henrion, Bart Van Overmeire, Marc Raes, An Bael, W Arts, Nathalie Kreins, Simon Fiesack, Karel Allegaert, Myriam Van Winckel, Nele De Mulder, Philippe Alliet, Anne Smits, Kirsten Keiren, Maissa Rayyan, Ann De Guchtenaere, Faculty of Arts and Philosophy, Materials and Chemistry, Electrochemical and Surface Engineering, Clinical sciences, Growth and Development, and Pediatrics

Subjects
Male, Pediatrics, medicine.medical_specialty, Consensus, Vitamin K, Term Birth, GREAT-BRITAIN, CLOTTING FACTORS, Review, Vitamin k, Placebo, Infant, Newborn, Diseases, vitamin K, Belgium, vitamin K deficiency bleeding, Medicine and Health Sciences, medicine, Humans, TX341-641, Dosing, PREMATURE-INFANTS, PEDIATRIC SURVEILLANCE UNIT, Nutrition and Dietetics, CHILDHOOD-CANCER, Nutrition. Foods and food supply, business.industry, Incidence, Incidence (epidemiology), Infant, Newborn, HEMORRHAGIC-DISEASE, IRELAND, Vitamins, Term, MIXED MICELLAR PHYLLOQUINONE, Regimen, Oral vitamin, Female, prophylaxis, Neonatology, business, Vitamin K Deficiency Bleeding, preterm, term, Healthcare providers, Infant, Premature, NEWBORN, Food Science
Abstract

Neonatal vitamin K prophylaxis is essential to prevent vitamin K deficiency bleeding (VKDB) with a clear benefit compared to placebo. Various routes (intramuscular (IM), oral, intravenous (IV)) and dosing regimens were explored. A literature review was conducted to compare vitamin K regimens on VKDB incidence. Simultaneously, information on practices was collected from Belgian pediatric and neonatal departments. Based on the review and these practices, a consensus was developed and voted on by all co-authors and heads of pediatric departments. Today, practices vary. In line with literature, the advised prophylactic regimen is 1 or 2 mg IM vitamin K once at birth. In the case of parental refusal, healthcare providers should inform parents of the slightly inferior alternative (2 mg oral vitamin K at birth, followed by 1 or 2 mg oral weekly for 3 months when breastfed). We recommend 1 mg IM in preterm

Published
2021

2. Liver-to-thoracic volume ratio: use at MR imaging to predict postnatal survival in fetuses with isolated congenital diaphragmatic hernia with or without prenatal tracheal occlusion

Author

Alexandra Benachi, Stéphanie Franchi-Abella, Mostafa Mokhtari, Mieke Cannie, Jacques Jani, Olivier Prodhomme, Vinciane Vlieghe, Anne-Gaël Cordier, Jocelyne de Laveaucoupet, Maud Cagneaux, Dorota Nowakowska, Marie-Victoire Senat, and Medical Imaging and Physical Sciences

Subjects
Male, medicine.medical_specialty, Diaphragmatic hernia, Prenatal diagnosis, Comorbidity, Sensitivity and Specificity, Prenatal Diagnosis, Infant Mortality, Medicine, Humans, Radiology, Nuclear Medicine and imaging, Lung volumes, Survival rate, Survival analysis, reproductive and urinary physiology, Hernia, Diaphragmatic, Fetus, business.industry, Incidence, tracheal occlusion, Infant, Newborn, Gestational age, Congenital diaphragmatic hernia, Reproducibility of Results, General Medicine, Organ Size, Thorax, medicine.disease, Magnetic Resonance Imaging, Survival Analysis, female genital diseases and pregnancy complications, Liver-to-thoracic volume ratio, Surgery, Survival Rate, Liver, embryonic structures, Female, business, Hernias, Diaphragmatic, Congenital, Tracheal Stenosis, Lung response
Abstract

To evaluate the relationship of the liver-to-thoracic volume ratio (LiTR) by MRI with postnatal survival in foetuses with isolated congenital diaphragmatic hernia (CDH). In 30 conservatively managed CDH foetuses and in 31 who underwent fetoscopic endoluminal tracheal occlusion (FETO), logistic regression analysis was used to investigate the effect on postnatal survival of the observed-to-expected (O/E) ratio of total foetal lung volume (TFLV), LiTR, gestational age at delivery, CDH side, intrathoracic position of the liver and, for those who underwent FETO, gestational age at FETO and occlusion period. For 19 foetuses undergoing FETO, a post-FETO MRI was available. The proportionate increase in O/E ratio of TFLV at 3–8 weeks after FETO was compared with the pre-FETO value and correlated with pre-FETO LiTR using linear regression analysis. For conservatively managed foetuses, only LiTR provided a significant prediction of postnatal survival. For foetuses undergoing FETO, LiTR and gestational age at delivery provided a significant independent prediction of postnatal survival. There was a significant inverse association between lung response and pre-FETO LiTR. In foetuses with CDH with/without FETO treatment, the LiTR is predictive of postnatal survival at discharge. In foetuses treated with FETO, LiTR is predictive of post-FETO lung response. • Congenital diaphragmatic hernia is usually managed conservatively before surgery soon after delivery • Fetoscopic endoluminal tracheal occlusion (FETO) has been introduced for severely affected foetuses • In conservatively managed CDH, the liver-to-thoracic volume ratio (LiTR) predicted postnatal survival best. • In severe CDH with prenatal FETO, LiTR also helped predict postnatal survival. • LiTR should be integrated into the prenatal decision-making for foetuses with CDH.

Published
2012

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