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Your search keyword '"Kenji Toyokuni"' showing total 5 results
Start Over Author "Kenji Toyokuni" Topic immunology
5 results on '"Kenji Toyokuni"'

1. Enhanced early skin treatment for atopic dermatitis in infants reduces food allergy

Author

Kiwako Yamamoto-Hanada, Tohru Kobayashi, Masashi Mikami, Hywel C. Williams, Hirohisa Saito, Mayako Saito-Abe, Miori Sato, Makoto Irahara, Yumiko Miyaji, Fumi Ishikawa, Kunihiko Tsuchiya, Risa Tamagawa-Mineoka, Yuri Takaoka, Yutaka Takemura, Sakura Sato, Hiroyuki Wakiguchi, Miyuki Hoshi, Osamu Natsume, Fumiya Yamaide, Miwako Seike, Yukihiro Ohya, Kumiko Morita, Eisuke Inoue, Tatsuki Fukuie, Shigenori Kabashima, Yusuke Inuzuka, Koji Nishimura, Kenji Toyokuni, Hiroya Ogita, Tomoyuki Kiguchi, Kazue Yoshida, Jumpei Saito, Hajime Hosoi, Norito Katoh, Mariko Morimoto, Koji Masuda, Makoto Kameda, Amane Shigekawa, Koji Yamasaki, Megumi Nagai, Motohiro Ebisawa, Tomoyuki Asaumi, Takaaki Itonaga, Shunji Hasegawa, Hiroki Yasudo, Mizuho Nagao, Takao Fujisawa, Ryuhei Yasuoka, Toshiharu Fujiyama, Naoki Shimojo, Taiji Nakano, Yasuto Kondo, Yuji Mori, Takahiro Kawaguchi, Masaki Futamura, Kazumitsu Sugiura, Akiyo Nagai, Sachiko Kaburagi, Hiroshi Kitazawa, Hiroshi Kido, and Shoji F. Nakayama

Subjects
Immunology, Immunology and Allergy
Published
2023
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2. Pollen-food allergy syndrome and component sensitization in adolescents: A Japanese population-based study

Author

Yumiko Miyaji, Shigenori Kabashima, Kenji Toyokuni, Yukihiro Ohya, Masami Narita, Koji Nishimura, Tatsuki Fukuie, Kiwako Yamamoto-Hanada, Makoto Irahara, Yusuke Inuzuka, Mayako Saito-Abe, Miori Sato, Hiroya Ogita, Tomoyuki Kiguchi, Fumi Ishikawa, and Yoshitsune Miyagi

Subjects
Male, Allergy, Plant Science, Adolescents, medicine.disease_cause, Cohort Studies, Families, Medical Conditions, 0302 clinical medicine, Japan, Allergies, Vegetables, Epidemiology, Medicine and Health Sciences, Prospective Studies, 030223 otorhinolaryngology, Children, Sensitization, Rhinitis, education.field_of_study, Multidisciplinary, Allergic Diseases, Plant Anatomy, Eukaryota, food and beverages, Syndrome, Plants, Japanese population, medicine.anatomical_structure, Pollen, Hay fever, Medicine, Female, Kiwifruit, Food Hypersensitivity, Research Article, Allergic Rhinitis, medicine.medical_specialty, Adolescent, Science, Immunology, Population, Food Allergies, Cross Reactions, Fruits, 03 medical and health sciences, Oral allergy syndrome, Environmental health, medicine, otorhinolaryngologic diseases, Humans, education, Nutrition, business.industry, Organisms, Biology and Life Sciences, Rhinitis, Allergic, Seasonal, Allergens, Rhinology, medicine.disease, Rhinitis, Allergic, Diet, Cross-Sectional Studies, Otorhinolaryngology, 030228 respiratory system, Age Groups, Food, Fruit, People and Places, Nasal Diseases, Clinical Immunology, Population Groupings, Clinical Medicine, business
Abstract

Allergic rhino-conjunctivitis with pollen allergy has been prevalent worldwide and Pollen-food allergy syndrome (PFAS) refers to individuals with pollen allergy who develop oral allergy syndrome (OAS) on consuming fruits and vegetables. The prevalence of PFAS varies by region and that in Japanese adolescents remains to be elucidated. In this cross-sectional study, we examined the epidemiological characteristics of PFAS in a general population of Japanese adolescents according to pollen allergy, OAS, and IgE component sensitization. Participants comprised adolescents, at age 13 years, from a prospective birth cohort study in Japan. We administered questionnaires to collect information from parents regarding pollen allergy, PFAS and OAS at each child’s age 13 years. ImmunoCAP ISAC was used to assess IgE component sensitization. Among 506 participants with a complete questionnaire and ISAC measurement results, 56.5% had a history of hay fever, 16.0% had a history of OAS, 51.0% had pollen allergy, and 11.7% had a history of PFAS; additionally, 72.7% were sensitized to one or more tree, grass, and/or weed allergens. The most common sensitization (95.7%) among adolescents with pollen allergy was to Japanese cedar (Cry j 1). The most common causal foods were kiwi and pineapple (both 39.0%). Knowledge levels about PFAS were poor among affected adolescents. We found a high prevalence of PFAS among adolescents in Japan. Although it affects approximately 1/10 adolescents in the general population, public awareness regarding PFAS is poor. Interventional strategies are needed to increase knowledge and to prevent PFAS in the general population.

Published
2021

5. Impact of swimming school attendance in 3-year-old children with wheeze and rhinitis at age 5 years: A prospective birth cohort study in Tokyo

Author

Miori Sato, Makoto Irahara, Masami Narita, Kenji Toyokuni, Koji Nishimura, Fumi Ishikawa, Limin Yang, Yusuke Inuzuka, Tatsuki Fukuie, Yukihiro Ohya, Mayako Saito-Abe, Kiwako Yamamoto-Hanada, and Yumiko Miyaji

Subjects
Male, Allergy, Pulmonology, Physiology, Eczema, Social Sciences, Atopic Dermatitis, Logistic regression, Cohort Studies, Families, Habits, Sociology, Allergies, Medicine and Health Sciences, Smoking Habits, Prevalence, Psychology, Longitudinal Studies, Prospective Studies, Child, Children, Rhinitis, Schools, Multidisciplinary, Allergic Diseases, Atopic dermatitis, Child, Preschool, Medicine, Female, medicine.symptom, Birth cohort, School attendance, Research Article, Offspring, Science, Immunology, Dermatology, Education, Wheeze, medicine, Humans, Tokyo, Swimming, Educational Attainment, Respiratory Sounds, Asthma, Behavior, Biological Locomotion, business.industry, Biology and Life Sciences, Rhinology, medicine.disease, Otorhinolaryngology, Age Groups, People and Places, Nasal Diseases, Population Groupings, Clinical Immunology, Clinical Medicine, business, Demography
Abstract

BackgroundIn Japan, swimming school attendance is promoted as a form of therapy or as a prophylactic measure against asthma in young children. However, the putative beneficial effects have not been sufficiently verified.ObjectiveThe aim of the present study was to clarify whether or not swimming school attendance at age 3 years affects the onset and/or improvement of wheeze and rhinitis at age 5 years.MethodsThis study was a single-center, prospective, general, longitudinal cohort study (T-CHILD Study). Between November 2003 and December 2005, 1776 pregnant women were enrolled, and their offspring were followed up until age 5 years. Swimming school attendance at age 3 years and the presence of wheeze and/or rhinitis in the previous one year were examined using the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. The relationship between swimming school attendance and wheeze and/or rhinitis was analyzed using multivariable logistic regression analysis.ResultsData on the 1097 children were analyzed. At age 3 years, 126 (11.5%) children attended a swimming school, and at age 5 years, the prevalence of wheeze was 180 (16.4%) while that of rhinitis was 387 (35.3%). Swimming school attendance at age 3 showed no significant relationship with the development of either wheeze (aOR 0.83, 95% CI (0.43-1.60) or rhinitis (aOR 0.80, 95% CI (0.43-1.60) at age 5.ConclusionsSwimming school attendance at age 3 years showed neither a preventive nor therapeutic effect on wheeze or rhinitis at age 5 years. There is thus no scientific evidence yet that swimming school attendance has a positive impact on the development of childhood wheeze or rhinitis.

Published
2020
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