1. [Prevention and therapy with immunoglobulin SRK].
- Author
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Schnoz M, Ryser DH, Barandun S, and Eckmann L
- Subjects
- Adult, Bacterial Infections etiology, Drug Evaluation, Humans, Hydrogen-Ion Concentration, Immunoglobulins administration & dosage, Immunoglobulins adverse effects, Immunologic Deficiency Syndromes complications, Injections, Intravenous, Bacterial Infections prevention & control, Immunoglobulins therapeutic use, Immunologic Deficiency Syndromes drug therapy, Sepsis drug therapy
- Abstract
In a clinical study the tolerance and efficacy of a gamma-globulin, treated at pH 4, has been studied. This preparation manufactured by the "Zentrallaboratorium des Blutspendedienstes SRK" can be given intravenously without any risk of untoward reactions. It has been applied in high dosages up to 99 g per week. In 15 cases with primary humoral immunodeficiency, the frequency and the severity of acute bacterial infections were markedly reduced or completely absent. In 16 patients without antibody deficiency but suffering from severe septic-toxic infections, results with Immunglobulin SRK were encouraging and warrant further controlled studies.
- Published
- 1979