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694 results on '"Iminosugar"'

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1. Deconstructing Best‐in‐Class Neoglycoclusters as a Tool for Dissecting Key Multivalent Processes in Glycosidase Inhibition.

2. Synthesis and Biological Evaluation of New Dihydrofuro[3,2- b ]piperidine Derivatives as Potent α -Glucosidase Inhibitors.

3. Synthesis, α-mannosidase inhibition studies and molecular modeling of 1,4-imino-ᴅ-lyxitols and their C-5-altered N-arylalkyl derivatives

4. sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease

5. Synthesis and Biological Evaluation of New Dihydrofuro[3,2-b]piperidine Derivatives as Potent α-Glucosidase Inhibitors

6. Influence of Side Chain Conformation on the Activity of Glycosidase Inhibitors.

7. Structure, Function and Mechanism of N‐Glycan Processing Enzymes: endo‐α‐1,2‐Mannanase and endo‐α‐1,2‐Mannosidase.

8. Stereoselective Production of Imino‐d‐ribitol and C‐Azanucleosides through Electrochemical C−H Functionalization.

9. Structural characterisation of calnexin cycle components and assessment as antiviral targets

10. sp²-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease.

11. Fiber-like Action of d-Fagomine on the Gut Microbiota and Body Weight of Healthy Rats.

12. Multivalent Pyrrolidine Iminosugars: Synthesis and Biological Relevance.

13. Enantiomeric C-6 fluorinated swainsonine derivatives as highly selective and potent inhibitors of α-mannosidase and α-l-rhamnosidase: Design, synthesis and structure-activity relationship study.

14. Concise Synthesis of (S)-7-Hydroxy-5-aza-8a- epi - d -swainsonine from a d -Erythrose Derivative.

15. Investigational New Drug Enabling Nonclinical Safety Pharmacology Assessment of the Iminosugar UV-4, a Broad-Spectrum Host-Targeted Antiviral Agent.

16. Inhibition of endoplasmic reticulum glucosidases is required for in vitro and in vivo dengue antiviral activity by the iminosugar UV-4

17. Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene-α-d-glucofuranose

18. Pathogen‐induced inflammation is attenuated by the iminosugar MON‐DNJ via modulation of the unfolded protein response.

19. The mechanism of action of iminosugars as antiretrovirals

20. Synthesis and biological characterization of natural and designed sugars

21. Iminosugars as dengue virus therapeutics : molecular mechanisms of action of a drug entering clinical trials

22. Inhibitory effect of Morus australis leaf extract and its component iminosugars on intestinal carbohydrate-digesting enzymes.

23. Effect of Renal Function Impairment on the Pharmacokinetics, Safety, and Tolerability of the Iminosugar Sinbaglustat.

24. Multivalent Pyrrolidine Iminosugars: Synthesis and Biological Relevance

25. Design, synthesis and biological evaluation of glycosidase inhibitors in an anti-cancer setting

26. Structural and electrophysiological analysis of Hepatitis C Virus p7

27. Iminosugar Glucosidase Inhibitors Reduce Hepatic Inflammation in Hepatitis A Virus-Infected Ifnar1-/- Mice.

28. Electrochemical Synthesis of Imino-C-Nucleosides by "Reactivity Switching" Methodology for in situ Generated Glycoside Donors.

29. The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication.

30. The synthesis of azetidine and piperidine iminosugars from monosaccharides

31. The synthesis and biological evaluation of novel N-acetylhexosaminidase inhibitors

32. Rare monosaccharides and biologically active iminosugars from carbohydrate chirons

33. Seven‐Step Synthesis of All‐Nitrogenated Sugar Derivatives Using Sequential Overman Rearrangements.

34. Iminosugar 1-Deoxynojirimycin (DNJ) sebagai Antiviral Infeksi Virus Dengue

35. Iminosugars With Endoplasmic Reticulum α-Glucosidase Inhibitor Activity Inhibit ZIKV Replication and Reverse Cytopathogenicity in vitro

36. The Stereoselective Nitro-Mannich Reaction in the Synthesis of Active Pharmaceutical Ingredients and Other Biologically Active Compounds

37. Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

38. Eubiotic effect of buckwheat d-fagomine in healthy rats

39. Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis: a randomized controlled trial

40. The crystal structures of 3-O-benzyl-1,2-O-isopropylidene-5-O-methanesulfonyl-6-O-triphenylmethyl-α-d-glucofuranose and its azide displacement product

41. Structure of a GH51 α‐l‐arabinofuranosidase from Meripilus giganteus: conserved substrate recognition from bacteria to fungi.

42. Conformationally Restricted Oxazolidin‐2‐one Fused Bicyclic Iminosugars as Potential Glycosidase Inhibitors.

43. Kinetic analysis of inhibition of α-glucosidase by leaf powder from Morus australis and its component iminosugars.

44. Crystal structure of 6-azido-6-deoxy-1,2-O-isopropylidene- α-D-glucofuranose.

45. A multi-component reaction approach to the synthesis of potent antidiabetic agents five-membered iminosugars analogues.

47. Iminosugars: Therapeutic Applications and Synthetic Considerations

49. Catalytic asymmetric synthesis of stereoisomers of 1-C-n-butyl-LABs for the SAR study of α-glucosidase inhibition.

50. sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo.

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