Search

Your search keyword '"Tolmacheva, V. V."' showing total 6 results
Start Over Author "Tolmacheva, V. V." Topic hypercrosslinked polystyrene
6 results on '"Tolmacheva, V. V."'

6. A New Derivatizing Agent for Determining Nitrofuran Metabolites in Chicken Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry.

Author

Melekhin, A. O., Tolmacheva, V. V., Shubina, E. G., Dmitrienko, S. G., Apyari, V. V., Grudev, A. I., and Zolotov, Yu. A.

Subjects
*LIQUID chromatography-mass spectrometry, *EGGS, *METABOLITES, *HIGH performance liquid chromatography
Abstract

5-Nitro-2-furaldehyde is proposed as a new derivatizing agent for determining four nitrofuran metabolites: 3-amino-2-oxazolidinone, 3-amino-5-methylmorpholino-2-oxazolidinone, 1-aminohydantoin, and semicarbazide in chicken eggs by HPLC with tandem mass spectrometric detection. The derivatization products were identified; they are the initial nitrofurans: furazolidone, furaltadone, nitrofurantoin, and nitrofurazone, respectively. Sample preparation includes acid hydrolysis, derivatization, fat removal by hexane extraction, and the further purification of the extracts on cartridges packed with Diapak P-3 hypercrosslinked polystyrene. The method ensures the quantitative isolation of metabolites (recovery rates are 95 to 106%) and good reproducibility (RSD ≤ 13%). [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results