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Start Over Author "Boyle, Belema" Topic hyperandrogenism
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1. Maternal hyperandrogenism beginning from early pregnancy and progressing until delivery does not produce virilization of a female newborn.

Author

Bertalan R, Csabay L, Blazovics A, Rigo J Jr, Varga I, Halasz Z, Toldy E, Boyle B, and Racz K

Subjects
Adult, Androstenedione metabolism, Estradiol metabolism, Female, Fetal Development physiology, Hirsutism complications, Humans, Hyperandrogenism pathology, Infant, Newborn, Pregnancy, Aromatase metabolism, Hyperandrogenism complications, Polycystic Ovary Syndrome complications, Pregnancy Complications, Testosterone metabolism
Abstract

A 33-year-old primagravida with a history of polycystic ovary syndrome was referred because of symptoms of moderate hyperandrogenism. Serum hormone levels, measured regularly from the 7th week of pregnancy until delivery, showed very high increases of testosterone, androstenedione and estradiol. Ultrasound showed no evidence of adrenal or ovarian masses. She delivered a female newborn with normal female external genitalia. Umbilical cord hormone levels were normal, except for a modest increase of serum testosterone. After delivery the androgen levels of the mother returned to normal and the symptoms of hyperandrogenism were also slightly improved.

Published
2007
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