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The present work reports a simple, mild and efficient protocol for the reduction of xanthenediones to 8-hydroxy xanthenones and xanthene1,8-diols by using readily available, cost efficient, easy to handle sodium borohydride as the reducing agent. The products obtained are in good to excellent yields with a short reaction duration. The versatility of the reaction, mild reaction conditions, in combination of high yields and easy work-up makes this reaction noteworthy. The synthesized compounds were analyzed spectroscopically. Further, four derivatives were recrystallized and structures were confirmed by crystallographic studies. The crystal structures are stabilized by intermolecular O–H···O hydrogen bonds and C–H···O weak interactions. [ABSTRACT FROM AUTHOR]

In the title compound, C14H15N3O4S, the tetra­hydro­pyrimidine ring adopts a half-boat form. There are inter­molecular N—H⋯O hydrogen bonds and π–π stacking inter­actions. [ABSTRACT FROM AUTHOR]

The title compound, C21H24O6, is the reduced form of curcumin, and exhibits important cosmoceutical properties. The molecule is non-planar and the benzene rings positioned at the ends of the heptane chain are orthogonally placed, with a dihedral angle of 84.09 (7)° between them. The molecular geometry and H-atom locations reveal that the 'heptane-3,5dione' moiety exists in the keto-enol form, with the hydroxy H atom disordered over two adjacent sites. The packing of the molecules in the lattice is directed by strong O-H···O intermolecular hydrogen bonds, which generate two-dimensional sheets. These sheets are linked by C-H···O hydrogen bonds and weak C-H···π interactions to develop a threedimensional network. [ABSTRACT FROM AUTHOR]

The crystal structure of the title compound, C17H20N2O5, is stabilized by C—H...O and N—H...O hydrogen bonds. [ABSTRACT FROM AUTHOR]

In the title compound, C22H16N2S2, the benzothiazole and tolyl ring systems are inclined at an angle of 31.23 (8)°, and the dihedral angle between the phenyl and benzothiazole rings is 7.567 (2)°. In the crystal structure, intermolecular C—H...N hydrogen bonds link the molecules into a two-dimensional sheet and π–π stacking interactions [perpendicular distance 3.6170 (4) Å] reinforce the crystal cohesion. [ABSTRACT FROM AUTHOR]

In the title compound, C14H10O4S2·0.5CH3OH, the molecule adopts a gauche conformation around the central C—C bond. Intermolecular O—H...O hydrogen bonds between carboxyl groups link the molecules into zigzag chains. Between chains, the thiophene rings form π–π stacking interactions with a centroid–centroid distance of 3.98 Å. The methanol solvent molecule forms an O—H...O hydrogen bond to one carboxyl group and is disordered about a crystallographic centre of inversion. [ABSTRACT FROM AUTHOR]