1. First report of coexistence of MOG-antibody-positive disease and Crohn's disease
- Author
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Jean-François Rahier, Marie Philippart, Sophie Fastré, Frédéric London, UCL - SSS/IREC/GAEN - Pôle d'Hépato-gastro-entérologie, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service de neurologie, UCL - (MGD) Service de gastro-entérologie, UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire, and UCL - (SLuc) Service de neurologie
- Subjects
Adult ,Male ,Crohn's disease ,biology ,business.industry ,Multiple sclerosis ,Demyelinating Autoimmune Diseases, CNS ,General Medicine ,Disease ,medicine.disease ,Autoantigens ,Crohn Disease ,Neurology ,immune system diseases ,Immunology ,medicine ,biology.protein ,Humans ,Myelin-Oligodendrocyte Glycoprotein ,Neurology (clinical) ,Antibody ,business - Abstract
Myelin oligodendrocyte glycoprotein (MOG) antibody disease hasrecently emerged as a new inflammatory demyelinating condition ofthe central nervous system. MOG autoimmunity is increasingly cate-gorised as a distinct entity from aquaporin-4 (AQP4)-IgG-mediatedneuromyelitis optica spectrum disorders (NMOSD), although it is stillunder debate because there is a substantial phenotypic overlap betweenthese two disorders. In contrast to AQP4 positive NMOSD, poly-autoimmunity is less common in MOG-IgG-positive disease (Jariuset al., 2016; Cobo-Calvo et al., 2018). We report herein thefirst case ofsimultaneous occurrence of MOG-IgG-positive disease and Cohn's dis-ease (CD) in a young male presenting with recurrent myelitis andbrainstem syndrome
- Published
- 2019
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