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1. From DYMUS to DYPARK: Validation of a Screening Questionnaire for Dysphagia in Parkinson's Disease

Author

Dagna, Carlotta, Avenali, Micol, De Icco, Roberto, Gandolfi, Marialuisa, Solaro, Claudio, Restivo, Domenico, Bartolo, Michelangelo, Meneghello, Francesca, Sandrini, Giorgio, Tassorelli, Cristina, DYPARK SIRN Group:, M Berlangieri, Cristina, S, Alfonsi, E, Monti, E, Bertino, G, Tinazzi, M, Busselli, G, C De Paoli, Smania, N, Inglese, K, S De Santi, Taiocchi, N, Zucchelli, B, Ronzoni, G, Nordio, S, and Tonin, P

Subjects
medicine.medical_specialty, Multiple Sclerosis, Sensitivity and Specificity, 03 medical and health sciences, Speech and Hearing, 0302 clinical medicine, Swallowing, Cronbach's alpha, Internal medicine, Surveys and Questionnaires, otorhinolaryngologic diseases, medicine, Humans, 030223 otorhinolaryngology, business.industry, Swallowing Disorders, Gastroenterology, Area under the curve, Parkinson Disease, Dysphagia, Hepatology, Deglutition, Otorhinolaryngology, Parkinson’s disease, Screening, Observational study, medicine.symptom, business, Deglutition Disorders, 030217 neurology & neurosurgery
Abstract

Dysphagia is a common debilitating symptom in people with Parkinson’s Disease (PD), adequate screening of swallowing disorders is fundamental. The DYMUS questionnaire has shown very good characteristics for the screening of dysphagia in Multiple Sclerosis, and it might also prove useful for screening dysphagia in PD. The primary aim was to test and validate the DYMUS questionnaire in PD patients. This is an observational multicentric study involving 103 patients affected by PD. All subjects filled in the DYMUS and the Eating Assessment Tool (EAT-10) questionnaires. A subgroup of patients (n = 53) underwent a fiber-optic endoscopic evaluation of swallowing (FEES) and their dysphagia was scored by means of the Dysphagia Outcome Severity Scale (DOSS). DYMUS showed a relatively high level of internal consistency (Cronbach’s alpha 0.79). A significant positive correlation was found between the DYMUS and the EAT-10 scores (p p p

Published
2020

2. Enteral versus intravenous approach for the sedation of critically ill patients: A randomized and controlled trial 11 Medical and Health Sciences 1103 Clinical Sciences

Author

Mistraletti, G., Umbrello, M., Salini, Sara, Cadringher, P., Formenti, P., Chiumello, D., Villa, C., Russo, R., Francesconi, S., Valdambrini, F., Bellani, G., Palo, A., Riccardi, F., Ferretti, E., Festa, M., Gado, A. M., Taverna, M., Pinna, C., Barbiero, A., Ferrari, P. A., Iapichino, G., Morabito, A., Langer, M., Valenza, F., Malacrida, R., Rambaldi, M., Spanu, P., Anania, S., Andrighi, E., Di Carlo, A., Martinetti, F., Barello, Serena, Noto, A., Capello, G., Sabatelli, B., Brenna, G., Astori, M., Placido, P., Gattinoni, L., Protti, A., Pagan, F., Berto, V., Roselli, P., Ronzoni, G., Beck, E., Gaiotto, M., Radrizzani, D., Ferla, L., Giudici, R., Merlini, L., Pesenti, A., La Bruna, A., Rezoagli, E., Lucchini, A., Braschi, A., Niebel, T., Selvini, M., Cortesi, S., Quaini, A., Iotti, G., Contri, E., Sacchi, A., Livigni, S., Naretto, G., Deprado, A., Venturi Degli Esposti, V., Caironi, P., Radeschi, G., Odetto, L., Ferrero, D., Cognolato, S., Penso, R., Vacchelli, R., Cardellino, S., Bosco, E., Bresciani, A., Pozzo, I., Alessio, A., Clarindo Rodrigues, V., Biase, E., Vivaldi, N., Nava, A., Ponzetta, F., Bavutti, L., Martina, P., Palacios, B., and Bergonzini, G.

Subjects
Male, Simplified Acute Physiology Score, Patient care planning, Critical Illness, Central Nervous System Depressants, Hypnotics and sedatives, Antipruritics, Middle Aged, Hydroxyzine, Melatonin, Nursing education research, Aged, Anesthesia, Deep Sedation, Enteral Nutrition, Female, Humans, Hypnotics and Sedatives, Intensive Care Units, Poisson Distribution, Single-Blind Method, Settore MED/41 - ANESTESIOLOGIA
Published
2019

3. Albumin replacement in patients with severe sepsis or septic shock

Author

Gattinoni L, Caironi P, Pesenti A, Fumagalli R, Tognoni G, Romero M, Latini R, Masson S, Vincent JL, Suter PM, Valsecchi MG, Santosuosso A, Cavana M, Ortu A, Gabini R, Perno S, Anelli A, Amoruso R, Ferraris S, Borelli M, Massei R, Riva I, Poli G, Papagni G, Bortone F, Mamprin F, Keim R, Brivio M, Colageo U, Mimii EP, Sangiorgi G, Siniscalchi A, Pierucci E, Giovannitti A, Gentile C, Pascucci F, Antonini B, Zummo U, Valsecchi R, Cerisara M, Trezzi T, Dossena A, Ribola A, Tamayo L, Zoppellari R, Volta CA, Mangani V, Fanfani E, Chelazzi C, Bartoli T, Parrini V, Oggioni R, Fedele A, Molin A, Berri C, Guarino A, Isetta M, Bonfiglio M, Tissino F, Silvestri L, Milanesi M, Sbrana G, Motta E, Iannaco I, Casadio MC, Pasetti GS, Palandini A, Cascione C, Puscio D, Cellai F, Boccalatte D, Silvestri S, Fausto CI, Lupo V, Zompanti V, Iacobone E, Gattari D, Ronzoni G, Beck E, Francesconi S, Colombo R, Raimondi F, Castelli A, De Gasperi A, Radrizzani D, Ferla LE, Giudici R, Bellato V, Bordone G, Gavazzeni V, Lesmo A, Ripamonti D, Vesconi S, Papoff A, Rossi A, Noto A, Pezzi A, Zanforlin G, Kandil H, Ballotta A, Bettini F, Vaghi GM, Rossi S, Pessina C, Casagrande D, Trivellato A, Costagli V, Moise G, Furla M, Marelli S, Caspani L, Panigada M, Bruzzone P, Isgrò S, Abbruzzese C, Tagliabue P, Solca M, Bonazzi M, Cattaneo A, Rossi N, Andreoni P, Pasetto A, Girardis M, Barbieri E, Piazza O, Zagara G, Bono M, Galzerano A, Garzilli T, Dentini N, Bindi M, Biancofiore G, Mercante WP, Disconzi MM, Todesco N, Lunardi S, Sani E, Carli M, Bracciotti G, Gori V, Braccini P, Maggio G, Braschi A, Bottazzi A, Iotti G, Nicora B, Salati G, Salsi P, Antonelli M, Pennisi MA, Bello G, Caccese R, D'Ambrosio M, Rocco M, Sanseverino M, Gatta A, Nastasi M, Corsi A, Facondini F, Franchi F, Mongelli P, Ferrario M, Carulli F, Del Curto S, Schiappacasse G, Dalpiaz C, Armani S, Verderosa I, Marzullo A, Tonetti F, De Piero ME, Livigni S, Fiore G, Cerutti A, Erbetta S, Napolitano R, Pastorelli M, Bona F, Debernardi F, Gallo M, Segala V, Parigi L, Perzolla D, Marson F, Chiarandini P, Cammarano C, Sermann G, De Lucia S, Frigerio A, Distaso F, Franco R, Bossi E, Laudi C, De Nardin M, Violo T, Lazzari F, Vestali A, Della Mora E, Polati E, Martini A, Cristallini S, Totaro C, Milan B, Dan M, Ruberti S, Danzi V., GIARRATANO, Antonino, RAINERI, Santi Maurizio, CORTEGIANI, Andrea, Caironi, P, Tognoni, G, Masson, S, Fumagalli, R, Pesenti, A, Romero, M, Fanizza, C, Caspani, L, Faenza, S, Grasselli, G, Iapichino, G, Antonelli, M, Parrini, V, Fiore, G, Latini, R, Gattinoni, L, Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, Fanizza C, Caspani L, Faenza S, Grasselli G, Iapichino G, Antonelli M, Parrini V, Fiore G, Latini R, Gattinoni L, Vincent JL, Suter PM, Valsecchi MG, Santosuosso A, Cavana M, Ortu A, Gabini R, Perno S, Anelli A, Amoruso R, Ferraris S, Borelli M, Massei R, Riva I, Poli G, Papagni G, Bortone F, Mamprin F, Keim R, Brivio M, Colageo U, Mimii EP, Sangiorgi G, Siniscalchi A, Pierucci E, Giovannitti A, Gentile C, Pascucci F, Antonini B, Zummo U, Valsecchi R, Cerisara M, Trezzi T, Dossena A, Ribola A, Tamayo L, Zoppellari R, Volta CA, Mangani V, Fanfani E, Chelazzi C, Bartoli T, Oggioni R, Fedele A, Molin A, Berri C, Guarino A, Isetta M, Bonfiglio M, Tissino F, Silvestri L, Milanesi M, Sbrana G, Motta E, Iannaco I, Casadio MC, Pasetti GS, Palandini A, Cascione C, Puscio D, Cellai F, Boccalatte D, Silvestri S, Fausto CI, Lupo V, Zompanti V, Iacobone E, Gattari D, Ronzoni G, Beck E, Francesconi S, Colombo R, Raimondi F, Castelli A, De Gasperi A, Radrizzani D, Ferla LE, Giudici R, Bellato V, Bordone G, Gavazzeni V, Lesmo A, Ripamonti D, Vesconi S, Papoff A, Rossi A, Noto A, Pezzi A, Zanforlin G, Kandil H, Ballotta A, Bettini F, Vaghi GM, Rossi S, Pessina C, Casagrande D, Trivellato A, Costagli V, Moise G, Furla M, Marelli S, Panigada M, Bruzzone P, Isgrò S, Abbruzzese C, Tagliabue P, Solca M, Bonazzi M, Cattaneo A, Rossi N, Andreoni P, Pasetto A, Girardis M, Barbieri E, Piazza O, Giarratano A, Raineri SM, Cortegiani A, Zagara G, Bono M, Galzerano A, Garzilli T, Dentini N, Bindi M, Biancofiore G, Mercante WP, Disconzi MM, Todesco N, Lunardi S, Sani E, Carli M, Bracciotti G, Gori V, Braccini P, Maggio G, Braschi A, Bottazzi A, Iotti G, Nicora B, Salati G, Salsi P, Pennisi MA, Bello G, Caccese R, D'Ambrosio M, Rocco M, Sanseverino M, Gatta A, Nastasi M, Corsi A, Facondini F, Franchi F, Mongelli P, Ferrario M, Carulli F, Del Curto S, Schiappacasse G, Dalpiaz C, Armani S, Verderosa I, Marzullo A, Tonetti F, De Piero ME, Livigni S, Cerutti A, Erbetta S, Napolitano R, Pastorelli M, Bona F, Debernardi F, Gallo M, Segala V, Parigi L, Perzolla D, Marson F, Chiarandini P, Cammarano C, Sermann G, De Lucia S, Frigerio A, Distaso F, Franco R, Bossi E, Laudi C, De Nardin M, Violo T, Lazzari F, Vestali A, Della Mora E, Polati E, Martini A, Cristallini S, Totaro C, Milan B, Dan M, Ruberti S, and Danzi V

Subjects
Male, medicine.medical_specialty, ALBUMIN, SEPSIS, SEVERE SEPSIS, SEPTIC SHOCK, Sepsi, Serum albumin, Settore MED/41 - Anestesiologia, Aged, Albumins, Female, Humans, Isotonic Solutions, Middle Aged, Rehydration Solutions, Sepsis, Serum Albumin, Shock, Septic, Survival Rate, Treatment Outcome, Intensive care, medicine, albumin replacement, Survival rate, Isotonic Solution, Medicine (all), SEPSIS, biology, business.industry, Septic shock, Rehydration Solution, Septic, Albumin, SEPTIC SHOCK, Organ dysfunction, Shock, General Medicine, medicine.disease, Surgery, Anesthesia, Relative risk, biology.protein, medicine.symptom, business, Human
Abstract

BACKGROUND: Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established. METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution or crystalloid solution alone. In the albumin group, the target serum albumin concentration was 30 g per liter or more until discharge from the ICU or 28 days after randomization. The primary outcome was death from any cause at 28 days. Secondary outcomes were death from any cause at 90 days, the number of patients with organ dysfunction and the degree of dysfunction, and length of stay in the ICU and the hospital. RESULTS: During the first 7 days, patients in the albumin group, as compared with those in the crystalloid group, had a higher mean arterial pressure (P = 0.03) and lower net fluid balance (P

Published
2014

4. Positive end-expiratory pressure applied to the dependent lung during one-lung ventilation improves oxygenation and respiratory mechanics in patients with high FEV1

Author

Valenza, F., Ronzoni, G., Perrone, L., Valsecchi, M., Sibilla, S., Nosotti, M., Santambrogio, L., Cesana, B.M., and Gattinoni, L.

Subjects
Male, Analysis of Variance, Settore MED/21 - Chirurgia Toracica, Posture, Settore MED/41 - Anestesiologia, Middle Aged, Thoracic Surgical Procedures, Respiration, Artificial, Respiratory Function Tests, Oxygen, Positive-Pressure Respiration, Treatment Outcome, Anesthesiology and Pain Medicine, Forced Expiratory Volume, Respiratory Mechanics, Humans, Female, Blood Gas Analysis
Abstract

The aim of this study was to test the efficacy of positive end-expiratory pressure (PEEP) to the dependent lung during one-lung ventilation, taking into consideration underlying lung function in order to select responders to PEEP.Forty-six patients undergoing open-chest thoracic surgical procedures were studied in an operating room of a university hospital. Patients were randomized to receive zero end-expiratory pressure (ZEEP) or 10 cmH2O of PEEP to the dependent lung during one-lung ventilation in lateral decubitus. The patients were stratified according to preoperative forced expiratory volume in 1 s (FEV1) as an indicator of lung function (below or above 72%). Oxygenation was measured in the supine position, in the lateral decubitus with an open chest, and after 20 min of ZEEP or PEEP. The respiratory system pressure-volume curve of the dependent hemithorax was measured in supine and open-chest lateral decubitus positions with a super-syringe.Application of 10 cmH2O of PEEP resulted in a significant increase in PaO2 (P0.05). This did not occur in ZEEP group, considered as a time matched control. PEEP improved oxygenation only in patients with high FEV1 (from 11.6+/-4.8 to 15.3+/-7.1 kPa, P0.05). There was no significant change in the low FEV1 group. Dependent hemithorax compliance decreased in lateral decubitus, more in patients with high FEV1 (P0.05). PEEP improved compliance to a greater extent in patients with high FEV1 (from 33.6+/-3.6 to 48.4+/-3.9 mLcmH2O(-1), P0.05).During one-lung ventilation in lateral decubitus, PEEP applied to the dependent lung significantly improves oxygenation and respiratory mechanics in patients with rather normal lungs as assessed by high FEV1.

Published
2004
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5. Unilateral testicular microlithiasis

Author

Menchinelli P, De Giovanni L, Belli P, PASQUALINO MANASIA, Jm, Weir, and Ronzoni G

Subjects
Adult, Male, Testis, Humans, Lithiasis, Testicular Diseases
Abstract

Testicular microlithiasis is a rare pathology which usually affects both testicles (less than 100 cases have been described in the literature), histologically characterized by numerous calcified deposits situated inside the seminiferous tubules, the diameter of which does not usually exceed 2 mm. The pathogenesis of the phenomenon is not completely clear; it has however been noted that there is a higher incidence in patients affected by cryptorchidism, subfertility, Klinefelter's syndrome and in particular those with testicular neoplasms, although the reason for this remains obscure. The case reported seems atypical in that there is no association with the conditions mentioned above and the finding is monolateral, something which is unusual in the literature reviewed.

Published
1999

6. Neurological assessment with validated tools in general ICU: multicenter, randomized, before and after, pragmatic study to evaluate the effectiveness of an e-learning platform for continuous medical education

Author

Mistraletti, G, Umbrello, M, Anania, S, Andrighi, E, Di Carlo, A, Martinetti, F, Barello, S, Sabbatini, G, Formenti, P, Maraffi, T, Marrazzo, F, Palo, A, Bellani, G, Russo, R, Francesconi, S, Valdambrini, F, Cigada, M, Riccardi, F, Moja, E, Iapichino, G, Spanu, P, Cappello, G, Baglio, L, Sabatelli, B, Brenna, G, Astori, M, Villa, C, Placido, P, Gattinoni, L, Protti, A, Pagan, F, Berto, V, Sparacino, C, Roselli, P, Noé, E, Mauri, I, Poti, F, Ronzoni, G, Beck, E, Gaiotto, M, Radrizzani, D, Ferla, L, Giudici, R, Merlini, L, Pesenti, A, Rezoagli, E, La Bruna, A, Lucchini, A, Braschi, A, Niebel, T, Selvini, M, Cortesi, S, Quaini, A, Iotti, G, Contri, E, Sacchi, A, Scartezzini, A, Malagò, G, Furletti, F, Morandini, M, Mistraletti, G, Umbrello, M, Anania, S, Andrighi, E, Di Carlo, A, Martinetti, F, Barello, S, Sabbatini, G, Formenti, P, Maraffi, T, Marrazzo, F, Palo, A, Bellani, G, Russo, R, Francesconi, S, Valdambrini, F, Cigada, M, Riccardi, F, Moja, E, Iapichino, G, Spanu, P, Cappello, G, Baglio, L, Sabatelli, B, Brenna, G, Astori, M, Villa, C, Placido, P, Gattinoni, L, Protti, A, Pagan, F, Berto, V, Sparacino, C, Roselli, P, Noé, E, Mauri, I, Poti, F, Ronzoni, G, Beck, E, Gaiotto, M, Radrizzani, D, Ferla, L, Giudici, R, Merlini, L, Pesenti, A, Rezoagli, E, La Bruna, A, Lucchini, A, Braschi, A, Niebel, T, Selvini, M, Cortesi, S, Quaini, A, Iotti, G, Contri, E, Sacchi, A, Scartezzini, A, Malagò, G, Furletti, F, and Morandini, M

Subjects
Adult, Male, medicine.medical_specialty, Critical Care, Sedation, MEDLINE, Settore M-PSI/06 - PSICOLOGIA DEL LAVORO E DELLE ORGANIZZAZIONI, medical, law.invention, Education, Education, Distance, 03 medical and health sciences, Neurological assessment, 0302 clinical medicine, Randomized controlled trial, law, medicine, Humans, distance-Education, continuing-Neurophysiological monitoring-Pain-Delirium, Pain Measurement, Neurologic Examination, Medical education, 030505 public health, Distance, Critically ill, business.industry, Delirium, 030208 emergency & critical care medicine, Pain scale, Continuing, Middle Aged, Education, distance-Education, medical, continuing-Neurophysiological monitoring-Pain-Delirium, Intensive Care Units, Anesthesiology and Pain Medicine, Controlled Before-After Studies, Assessment methods, Physical therapy, Education, Medical, Continuing, Female, Clinical Competence, medicine.symptom, 0305 other medical science, business, Computer-Assisted Instruction
Abstract

BACKGROUND: International guidelines recommend systematic assessment of pain, agitation/sedation and delirium with validated scales for all ICU patients. However, these evaluations are often not done. We have created an e-learning training platform for the continuous medical education, and assessed its efficacy in increasing the use of validated tools by all medical and nursing staff of the participating ICUs during their daily practice. METHODS: Multicenter, randomized, before and after study. The eight participating centers were randomized in two groups, and received training at different times. The use of validated tools (Verbal Numeric Rating or Behavioral Pain Scale for pain; Richmond Agitation-Sedation Scale for agitation; Confusion Assessment Method for the ICU for delirium) was evaluated from clinical data recorded in medical charts during a week, with follow-up up to six months after the training. All the operators were invited to complete a questionnaire, at baseline and after the training. RESULTS : Among the 374 nurses and physicians involved, 140 (37.4%) completed at least one of the three courses. The assessment of pain (38.1 vs. 92.9%, P

9. [Loco-regional intra-arterial therapy of liver neoplasms]

Author

Alcini, E, Wiel Marin, A, Ronzoni, G, and Pigliucci, Gm

Subjects
Adult, Male, Liver Neoplasms, Middle Aged, Hepatic Artery, Liver Circulation, Humans, Aged, Radionuclide Imaging, Catheterization, Fluorouracil, Neoplasm Metastasis, Female, Settore MED/18 - Chirurgia Generale
Published
1969

10. Hypernatremia and moderate-to-severe hyponatremia are independent predictors of mortality in septic patients at emergency department presentation: A sub-group analysis of the need-speed trial

Author

Giulia Ronzoni, Mattia Bellan, Nicola Fiotti, Salvatore Di Somma, Gianni Biolo, Luigi Mario Castello, Francesco Gavelli, Filippo Patrucco, Pier Paolo Sainaghi, Maria Lorenza Muiesan, Gian Carlo Avanzi, Filippo Mearelli, Enrico Lupia, Livia Salmi, Marco Baldrighi, Castello, L. M., Gavelli, F., Baldrighi, M., Salmi, L., Mearelli, F., Fiotti, N., Patrucco, F., Bellan, M., Sainaghi, P. P., Ronzoni, G., Di Somma, S., Lupia, E., Muiesan, M. L., Biolo, G., and Avanzi, G. C.

Subjects
medicine.medical_specialty, Prognosi, Sepsi, 030204 cardiovascular system & hematology, Sepsis, 03 medical and health sciences, 0302 clinical medicine, Septic shock, Internal Medicine, Humans, Medicine, 030212 general & internal medicine, Risk stratification, Retrospective Studies, Hypernatremia, business.industry, Mortality rate, nutritional and metabolic diseases, Hyponatremia, Prognosis, Emergency department, medicine.disease, Emergency medicine, Presentation (obstetrics), Emergency Service, Hospital, business
Abstract

Study objective: Early risk stratification of septic patients presenting to the emergency department (ED) is challenging. The aim of the study was to evaluate the prognostic role of plasmatic sodium level (PNa+) derangements at ED presentation in septic patients. Methods: According to PNa+ at ED presentation patients were divided in eunatremic (136–145 mEq/L), hypernatremic (>145 mEq/L) and hyponatremic (

Published
2021

11. Use of psychotropic drugs in Lombardy in time of economic crisis (2007–2011): A population-based study of adult employees

Author

Giorgio Vittadini, Massimiliano Beghi, Cesare Maria Cornaggia, Gloria Ronzoni, Mario Mezzanzanica, Vittadini, G, Beghi, M, Mezzanzanica, M, Ronzoni, G, and Cornaggia, C

Subjects
Adult, Male, Pediatrics, medicine.medical_specialty, Poison control, economic crisis, Drug Prescriptions, Suicide prevention, Prescription, Occupational safety and health, Young Adult, Sex Factors, work, Injury prevention, Basic education, medicine, Humans, Medical prescription, Biological Psychiatry, Retrospective Studies, Consumption (economics), Psychotropic Drugs, antidepressant, business.industry, Age Factors, food and beverages, Human factors and ergonomics, Middle Aged, Antidepressive Agents, Psychiatry and Mental health, Economic Recession, Italy, Research Design, Educational Status, Female, business, Demography
Abstract

Over recent years, there has been a noticeable increase in the prescription of psychotropic drugs (PDs), particularly antidepressants (ADs). The aim of this retrospective study was to evaluate the consumption of PDs by all adult employees in Lombardy aged >18 years in the period 2007-2011 and the possible changes induced by the “economic crisis” in this highly productive area of Italy. The subjects were classified by gender, age class, nationality, education and province. During the five-year period, there were 3,554,860 employed adults in Lombardy, of whom 277,865 (7.8%) used PDs. The use of PDs (particularly ADs) was associated with being an Italian woman aged >55 years with a basic education and a blue collar job. The lower prevalence in immigrants may be due to the difficulty in gaining access to health services. The increase in PD use can be attributed more specifically to ADs and anti-epileptic drugs with anxiolytic properties. Although continuously increasing, the use of AD fluctuated and was greater during the fall and winter. The increase involved all of the provinces in Lombardy in a similar manner. In 39% of cases, the use of PDs (and particularly ADs) was limited to one trimester, although the AD guidelines suggest at least 6-12 months of treatment.

Published
2014
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12. Psychotropic Drug Consumption and Employement Status in Time of Economic Crisis (2007-2011)

Author

Giorgio Vittadini, Cesare Maria Cornaggia, Massimiliano Beghi, W Maffenini, Gloria Ronzoni, Mario Mezzanzanica, Cornaggia, C, Beghi, M, Mezzanzanica, M, Ronzoni, G, Vittadini, G, and Maffenini, W

Subjects
Adult, Employment, Male, medicine.medical_specialty, Databases, Factual, media_common.quotation_subject, Recession, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Prescription, Psychotropic Drugs, Unemployment, Great Recession, Administrative Data, Permanent Job, Humans, Medicine, 030212 general & internal medicine, Medical prescription, Psychiatry, Depression (differential diagnoses), media_common, Consumption (economics), Psychotropic Drugs, business.industry, Permanent employment, Middle Aged, 030227 psychiatry, Psychiatry and Mental health, Economic Recession, Psychotropic drug, Italy, Case-Control Studies, Propensity score matching, Unemployment, Female, business
Abstract

Psychiatric disorders and in particular depression have increased during the "Great Recession". The aim of this study was to investigate the consumption of psychotropic drugs in people who lost their permanent employment, using administrative data. The study considered all of the subjects domiciled in Lombardy, Northern Italy, who lost a permanent employment between 2008 and 2010, not assuming psychotropic drugs and who did not find a new job within the following 12 months. The control group included people who did not lose permanent job in the study period, matched to the cases for gender, age, nationality, skill level, education and economic sector, using propensity score matching. The subjects who lost their permanent employment were 17 % more likely to receive one or more drug prescriptions than the controls, but the difference was significant only for males. Females, subjects aged >50 years, low skill level workers and Italians were more likely to have received a prescription for psychotropic drugs than respectively males, subjects aged 20-29 years or aged 30-39 years, low skill level workers and non-Italians. The average number of drugs prescribed for those who lost their job and those who continued working was respectively 2.9 and 3.1. In conclusion, losing a permanent job increases significantly psychotropic drugs consumption in males but not in females.

Published
2017

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