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1. From pregnancy to breastfeeding: adequate maternal body mass index is essential to prevent a high body mass index in your children

Author: Caroline Brand, Camila Felin Fochesatto, Emilio Villa-González, João Francisco de Castro Silveira, Arieli Fernandes Dias, Fernanda Quevedo Alves, Anelise Reis Gaya, Jane Dagmar Pollo Renner, and Cézane Priscila Reuter
Subjects: Adolescent, Endocrinology, Diabetes and Metabolism, Mothers, Body Mass Index, Pregnancy Complications, Breast Feeding, Cross-Sectional Studies, Endocrinology, Pregnancy, Pediatrics, Perinatology and Child Health, Humans, Female, Obesity, Child
Abstract: Objectives To verify the associations between prenatal and perinatal factors with offspring body mass index (BMI) and the moderator role of maternal BMI in this relationship. Methods Cross-sectional study developed with 1,562 children and adolescents aged between 6 and 17 years, as well as their mothers, from southern Brazil. The prenatal and perinatal factors, weight, and height for the calculation of maternal BMI were self-reported. For the calculation of BMI, weight and height of the child/adolescent were measured on an anthropometric scale with a coupled stadiometer. Linear regression models were used for the moderation analysis. All analyzes were adjusted for the mother’s and child’s age, sex, sexual maturation, skin color/race, and educational level. Results cesarean as type of delivery (β=0.66; 95% CI=0.22 1.04; p=0.002) and pregnancy complications (β=0.60; 95% CI=0.15 1.04; p=0.002) were positively associated with offspring BMI. Schoolchildren who were breastfed for 4–6 months showed −0.56 kg/m2 of BMI (95% CI=−1.06–0.06; p=0.02). Birth weight was also associated with BMI, with low weight being inversely (β=−0.59; 95% CI=−1.03–0.15; p=0.008), while overweight was positively related (β=0.84; 95% CI=0.08 1.60; p=0.02). The moderation analysis indicated a positive interaction between the mother’s BMI and cesarean, pregnancy complications, and smoking with the offspring’s BMI. On the other hand, there was an inverse association between breastfeeding from 7 to 12 months and the offspring BMI, only in mothers with high BMI. Conclusions Adequate maternal BMI is essential to prevent a high BMI in their children, especially when considering the influence of prenatal and perinatal risk factors.
Published: 2022

2. Team sports, running, walking: activity-specific associations with perceived environmental factors in adolescents

Author: Arieli Fernandes Dias, Camila Felin Fochesatto, Inacio Crochemore-Silva, Caroline Brand, Jorge Mota, Anelise Reis Gaya, and Adroaldo Cezar Araujo Gaya
Subjects: Male, Built environment, Public health, Youth, Adolescent, Physical activity, Transporte ativo, Atividade física, Health Policy, Public Health, Environmental and Occupational Health, Team Sports, Ambiente construído, Walking, Juventude, Running, Residence Characteristics, Saúde pública, Surveys and Questionnaires, Humans, Female, Active transport, Exercise
Abstract: This study aimed to analyze the association between the practice of different types of physical activity (PA) with perceived environmental factors in boys and girls adolescents. Were evaluated 1,130 adolescents from Porto Alegre, Brazil. To evaluate different PA, students answered whether or not they practiced walking, running, team sports, and others general PA. Perceived environmental factors were assessed through Neighborhood Environment Walkability Scale for Youth (NEWS-Y). Analyses were performed using logistic regression. Adolescents who reported perceiving a distance up to 20 minutes to walking/running track, had their chances of practicing all types of PA increased in the total sample and for girls. For walking, it was also found an association with access in adolescents. For girls, it was found an association between shortest distance to indoor recreation or exercise facility and other playing fields/court with running and team sports. Aesthetics and road safety were associated with team sports in adolescents. Other general PA were associated with park, bike/hiking/walking trails in the total sample and for girls. Therefore, for each type of PA, specific associations of perceived environmental factors were found. Resumo Este estudo teve como objetivo analisar a associação entre a prática de diferentes tipos de atividade física (AF) com fatores ambientais percebidos em meninos e meninas adolescentes. Foram avaliados 1.130 adolescentes de Porto Alegre, Brasil. Para avaliar diferentes AF, os alunos responderam se praticavam ou não caminhada, corrida, esportes coletivos e outras AF em geral. Fatores ambientais percebidos foram avaliados pelo Neighborhood Environment Walkability Scale for Youth. As análises foram realizadas por meio de regressão logística. Adolescentes que relataram perceber uma distância de até 20 minutos para pista de caminhada/corrida tiveram suas chances de praticar todos os tipos de AF aumentadas na amostra total e para as meninas. Para caminhada, também foi encontrada associação com o acesso em adolescentes. Para as meninas, foi encontrada uma associação entre a menor distância para instalações de exercícios e outros campos de jogos/quadra com corrida e esportes coletivos. A estética e a segurança de ruas foram associadas com esportes coletivos em adolescentes. Outras AF gerais foram associadas com parque e trilhas de bicicleta/caminhada na amostra total e para meninas. Portanto, para cada tipo de AF, foram encontradas associações específicas de fatores ambientais percebidos.
Published: 2022

3. The genetic predisposition to obesity has no influence on waist circumference when screen time and sleep duration are adequate in children and adolescents

Author: Antonio García-Hermoso, Andréia Rosane de Moura Valim, Ana Paula Sehn, Pâmela Ferreira Todendi, Anelise Reis Gaya, Vanessa Suñé Mattevi, Caroline Brand, and Cézane Priscila Reuter
Subjects: Pediatric Obesity, Waist, Adolescent, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Physical Therapy, Sports Therapy and Rehabilitation, Polymorphism, Single Nucleotide, Body Mass Index, Screen Time, Screen time, Polymorphism (computer science), medicine, Genetic predisposition, Humans, Genetic Predisposition to Disease, Orthopedics and Sports Medicine, Child, business.industry, nutritional and metabolic diseases, General Medicine, Circumference, medicine.disease, Moderation, Obesity, Trunk, Cross-Sectional Studies, Obesity, Abdominal, Waist Circumference, Sleep, business, Demography
Abstract: The aim of the present study was to verify whether the amount of sleep duration, screen time, and physical activity moderate the relationship between FTO rs9939609 polymorphism and waist circumference (WC) in children and adolescents. This is a cross-sectional study conducted with 1338 children and adolescents, aged between 6 and 17 years. Lifestyle habits were assessed through self-reported questionnaire. WC was measured on the narrowest part of the trunk between the last rib and the iliac crest. FTO rs9939609 polymorphism was genotyped by real time polymerase chain reaction. The PROCESS macro for the SPSS was used for moderation analyses, through multiple linear regression models. Results indicated significant interactions were found between sleep duration and screen time X FTO rs9939609, showing that these lifestyle behaviours are moderators in the relationship between a genetic predisposition for obesity and higher WC. For physical activity, there was no significant interaction. Therefore, sleeping more than 564 min a day (i.e. 9.4 h) and spending no more than 233 min in front of screen may counteract the genetic predisposition to obesity in children and adolescents.
Published: 2021

4. Association between physical fitness components and fluid intelligence according to body mass index in schoolchildren

Author: Arieli Fernandes Dias, Camila Felin Fochesatto, Aline Riboli Marasca, Caroline Brand, Carlos Cristi-Montero, Anelise Reis Gaya, Adroaldo Cezar Araujo Gaya, and Denise Ruschel Bandeira
Subjects: Male, Pediatric Obesity, Intelligence, Physical fitness, Protective factor, Fluid intelligence, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Developmental and Educational Psychology, medicine, Humans, 0501 psychology and cognitive sciences, Cognitive skill, Child, Association (psychology), business.industry, 05 social sciences, Cognition, Overweight, medicine.disease, Obesity, Cross-Sectional Studies, Neuropsychology and Physiological Psychology, Physical Fitness, business, Psychology, Body mass index, 030217 neurology & neurosurgery, 050104 developmental & child psychology, Clinical psychology
Abstract: Physical fitness is considered a protective factor for children's general health and has been related to enhanced cognitive functioning. However, it appears that cognition could be affected in children with overweight or obesity. The present study aimed to determine the relationship between physical fitness components and fluid intelligence in normal-weight and overweight/obese children. In this cross-sectional study, a total of 317 schoolchildren participated (165 boys, 52.05%), aged between six and 11 years old (1st to 5th grade), belonging to a public school in the south of Brazil. Psychologists evaluated fluid intelligence through the Raven's Colored Progressive Matrix Test. The physical fitness evaluation followed the procedures of the "Brazil Sports Project". Weight and height were measured to determine body mass index and generalized linear regression analyses were used with a 95% confidence interval. Our results showed that agility was inversely associated with fluid intelligence only in the overweight/obese group (
Published: 2021

5. Association between sociodemographic, dietary, and substance use factors and accelerometer-measured 24-hour movement behaviours in Brazilian adolescents

Author: Bruno Gonçalves Galdino da Costa, Kelly Samara da Silva, Jean-Philippe Chaput, Marcus Vinicius Veber Lopes, Diego Augusto Santos Silva, and Anelise Reis Gaya
Subjects: Male, medicine.medical_specialty, Social characteristics, Adolescent, Substance-Related Disorders, Physical activity, Psychological intervention, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Environmental health, Accelerometry, medicine, Humans, 030212 general & internal medicine, Social determinants of health, Association (psychology), Exercise, Socioeconomic status, business.industry, Public health, Diet, Cross-Sectional Studies, Pediatrics, Perinatology and Child Health, Female, Sedentary Behavior, Substance use, business
Abstract: Sociodemographic factors and lifestyle behaviours were evidenced as correlates of self-reported 24-hour movement behaviours in high-income settings. However, it is unclear how these relations occur in a middle-income country setting, with unique cultural and social characteristics. This study aimed to examine the association between sociodemographic, dietary, and substance use factors with accelerometer-measured 24-hour movement behaviours in Brazilian adolescents. Information on sex, age, socioeconomic status (SES), family structure, dietary behaviours, and history of substance use were collected by a questionnaire. Sleep duration, sedentary behaviour, and light- and moderate-to-vigorous physical activity (LPA and MVPA) were measured using wrist-worn accelerometers. On average, females slept more (β = 21.09, 95%CI 13.18; 28.98), engaged in more LPA (β = 17.60, 95%CI 8.50; 27.13), and engaged in less sedentary behaviour (β = -16.82, 95%CI -30.01; -4.30) and MVPA (β = -4.76, 95%CI -7.48; -1.96) than males. Age and sedentary behaviour were positively associated (β = 8.60, 95%CI 2.53; 14.64). Unprocessed foods were positively related to LPA (β = 2.21, 95%CI 0.55; 3.92), whereas processed foods were positively related to sedentary behaviour (β = 3.73, 95%CI 0.03; 7.38) and inversely related to MVPA (β = -0.89, 95%CI -1.68; -0.10). Family structure, SES, and substance use factors were not significantly associated with any 24-hour movement behaviour.Conclusions: Sex, age, and dietary behaviours, unlike SES or substance use, were associated with 24-hour movement behaviours in this sample of Brazilian adolescents and are important factors to consider in interventions, policies, and practice. What is Known: • The 24-hour movement behaviours are composed of sleep, sedentary behaviour, and physical activity and are important determinants of health. • Most adolescents do not engage in adequate levels of physical activity, sedentary behaviour, and sleep, and there is a need to better understand factors related to these behaviours. What is New: • Sex, age, and dietary behaviours were associated with the 24-hour movement behaviours. • No associations were found between socioeconomic status and substance use with the 24-hour movement behaviours.
Published: 2021

6. Neck circumference and cardiometabolic risk in children and adolescents: the moderator role of cardiorespiratory fitness

Author: Carlos Cristi-Montero, Cézane Priscila Reuter, Elza Daniel de Mello, Anelise Reis Gaya, Letícia Welser, César Agostinis-Sobrinho, Ana Paula Sehn, and Caroline Brand
Subjects: Adult, Male, Neck circumference, Aptidão física, medicine.medical_specialty, Pediatrics, Adolescent, Criança, RJ1-570, Body Mass Index, 03 medical and health sciences, Síndrome metabólica, 0302 clinical medicine, Risk Factors, medicine, Humans, 030212 general & internal medicine, Obesity, Child, Adolescente, Doenças cardiovasculares, Fatores de risco, Anthropometry, business.industry, Incidence (epidemiology), Public health, Cardiorespiratory fitness, 030229 sport sciences, Physical fitness, Moderation, Metabolic syndrome, Cross-Sectional Studies, Blood pressure, Obesidade, Cardiorespiratory Fitness, Cardiovascular Diseases, Pediatrics, Perinatology and Child Health, anthropometry, pediatrics, physical fitness, obesity, metabolic syndrome, Female, Waist Circumference, business, Body mass index, Antropometria, Research Article
Abstract: Background The increased incidence of cardiometabolic risk factors has become a public health issue, especially in childhood and adolescence. Thus, early identification is essential to avoid or reduce future complications in adulthood. In this sense, the present study aimed to verify the influence of cardiorespiratory fitness (CRF) as a moderator in the association between neck circumference (NC) and cardiometabolic risk in children and adolescents. Methods Cross-sectional study that included 2418 randomly selected children and adolescents (52.5% girls), aged 6 to 17 years old. Anthropometric measurements, such as NC and body mass index (BMI), and CRF was measured by the six-minute running/walking test, as well as cardiometabolic risk (systolic blood pressure, glucose, HDL-C, and triglycerides), were assessed. Results For all age groups, NC showed a negative relationship with CRF. A significant interaction term was found for CRF x NC with cardiometabolic risk for children (6 to 9 years old), early adolescents (10 to 12 years old), and middle adolescents (13 to 17 years old). It was found that children who accomplished more than 1092.49 m in CRF test were protected against cardiometabolic risk when considering NC. In adolescents, protection against cardiometabolic risk was found when the CRF test was completed above 1424.14 m and 1471.87 m (early and middle stage, respectively). Conclusions CRF is inversely associated with NC and acts as a moderator in the relationship between NC and cardiometabolic risk in children and adolescents. Therefore, this detrimental health impact linked to fatness might be attenuated by improving CRF levels.
Published: 2021

7. Body fat percentage, cardiorespiratory fitness and arterial blood pressure in children and adolescents: a longitudinal analysis

Author: Caroline Brand, Ana Paula Sehn, Camila Felin Fochesatto, João Francisco de Castro Silveira, Jorge Mota, David Martinez Gomez, Anelise Reis Gaya, Cézane Priscila Reuter, and Jane Dagmar Pollo Renner
Subjects: Adipose Tissue, Adolescent, Cardiorespiratory Fitness, Humans, Arterial Pressure, Blood Pressure, Longitudinal Studies, Child, Cardiology and Cardiovascular Medicine, Adiposity, Body Mass Index
Abstract: Background A better understanding of how cardiorespiratory fitness (CRF) and adiposity interact to associate with arterial blood pressure over time remains inconclusive. Thus, the aim of the present study was to examine whether changes in CRF moderates the association between body fat percentage (BF%) and arterial blood pressure in children and adolescents. Methods This is an observational longitudinal study with 407 children and adolescents aged 8–17 years followed-up for three years from a city in Southern Brazil. Participants were evaluated in 2011 and 2014. CRF was measured by validated field-based tests following the Projeto Esporte Brazil protocols and peak oxygen uptake (VO2peak) was estimated. BF% was determined by the measures of tricipital and subscapular skinfolds using equations according to sex. Systolic and diastolic blood pressure (SBP, DBP) were measured with a sphygmomanometer according to standard procedures. Moderation analyses included multiple linear regression models adjusted for sex, age, pubertal status, height, socioeconomic level, skin color, and the arterial blood pressure variable itself at baseline. Results It was observed a significant inverse association between VO2peak at baseline with SBP (β = − 0.646 CI95% = − 0.976 − 0.316) and DBP (β = − 0.649 CI95% = − 0.923 − 0.375) at follow-up and a positive association between BF% at baseline with SBP (β = 0.274; CI95% = 0.094 0.455) and DBP (β = 0.301; CI95% = 0.150 0.453) at follow-up. In addition, results indicated a significant interaction term between changes in VO2peak and BF% at baseline with both SBP (p = 0.034) and DBP at follow-up (p = 0.011), indicating that an increase of at least 0.35 mL/kg/min and 1.78 mL/kg/min in VO2peak attenuated the positive relationship between BF% with SBP and DBP. Conclusion CRF moderates the relationship between BF% and SBP and DBP in children and adolescents.
Published: 2022

8. Associations of cardiorespiratory fitness and obesity parameters with blood pressure: fitness and fatness in youth Latin-American ethnic minority

Author: Eduardo Lusa Cadore, Cristian Álvarez, Jeison Alexander Ramos-Sepúlveda, Hugo Alejandro Carrillo, Cézane Priscila Reuter, Robinson Ramírez-Vélez, Pedro Delgado-Floody, Anelise Reis Gaya, Júlio Brugnara Mello, and Dirina González Devia
Subjects: Male, Cultural Studies, Latin Americans, Adolescent, education, Ethnic group, Blood Pressure, Disease, Body Mass Index, Arts and Humanities (miscellaneous), Ethnicity, medicine, Humans, Obesity, Child, Minority Groups, health care economics and organizations, business.industry, Public Health, Environmental and Occupational Health, Cardiorespiratory fitness, medicine.disease, Cross-Sectional Studies, Blood pressure, Adipose Tissue, Cardiorespiratory Fitness, Cardiovascular Diseases, Ethnic and Racial Minorities, Hypertension, Spite, Female, Waist Circumference, business, hormones, hormone substitutes, and hormone antagonists, Demography
Abstract: Background: In spite of wide international evidence about cardiorespiratory fitness (CRF) and adiposity in association with cardiovascular disease, there is poor evidence about this relationship in...
Published: 2020

9. Combination of sleep duration, TV time and body mass index is associated with cardiometabolic risk moderated by age in youth

Author: Jane Dagmar Pollo Renner, Cézane Priscila Reuter, Ana Paula Sehn, Caroline Brand, Arieli Fernandes Dias, Silvia Isabel Rech Franke, Roya Kelishadi, and Anelise Reis Gaya
Subjects: Male, Waist, Adolescent, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Saúde, Overweight, Adolescents, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Humans, Medicine, Obesity, 030212 general & internal medicine, Risk factor, Child, Adolescentes, Adiposity, Índice de massa corporal, business.industry, Prevention, Age Factors, Cardiorespiratory fitness, Prognosis, Moderation, medicine.disease, Televisão, Cross-Sectional Studies, Cardiovascular Diseases, Health, Pediatrics, Perinatology and Child Health, Female, Television, Prevenção e controle [Obesidade], medicine.symptom, Sleep, business, Body mass index, Brazil, Follow-Up Studies, Sono, Demography, Sleep duration
Abstract: Objectives The combination of sleep duration, television (TV) time and body mass index (BMI) may be related to the alteration of cardiometabolic risk. However, there are few studies that use these variables grouped, and showing the moderating role of age. This study aimed to verify if the combination of sleep duration, TV time and BMI is associated with cardiometabolic risk and the moderating role of age in this relationship in youth. Methods Cross-sectional study conducted with 1411 adolescents (611 male), aged 10–17 years. Sleep duration, TV time and BMI were assessed and grouped into eight categories. Cardiometabolic risk was assessed by a continuous metabolic risk score, including the following variables: low HDL-cholesterol, elevated triglycerides, dysglycemia, high systolic blood pressure, high waist circumference and low cardiorespiratory fitness. Generalized linear models were used to test moderation of age in the relationship between the eight categories of sleep duration/television time/BMI with cardiometabolic risk. Results Cardiometabolic risk factor showed association with all overweight or obesity independent of sleep time and TV time. Age moderated the relationship between sleep duration/television time/BMI with cardiometabolic risk. This association was stronger in younger adolescents (11 and 13 years), indicating that individuals with inadequate sleep, prolonged TV time and overweight/obesity present higher cardiometabolic risk values when compared to 15-year-old adolescents. Conclusion Overweight/obesity, independently of sleep duration and TV time, is the main risk factor for cardiometabolic disorders in adolescence. When moderated by age, younger adolescents that presented the combination of risk factors had higher cardiometabolic risk.
Published: 2020

10. Association between cardiorespiratory fitness and cardiometabolic risk factors in Brazilian children and adolescents: the mediating role of obesity parameters

Author: Jorge Mota, Caroline Brand, Leticia Borfe, Cézane Priscila Reuter, Anelise Reis Gaya, Michael J. Duncan, and Jane Dagmar Pollo Renner
Subjects: Male, Pediatric Obesity, Mediation (statistics), medicine.medical_specialty, Waist, Adolescent, Crianças, Metabolic health, Overweight, Waist-to-height ratio, Body Mass Index, Percentage of body fat, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, 030225 pediatrics, Internal medicine, medicine, Humans, 030212 general & internal medicine, Child, Adolescentes, Body mass index, Índice de massa corporal, business.industry, Cardiometabolic Risk Factors, Cardiorespiratory fitness, medicine.disease, Obesity, Cross-Sectional Studies, Blood pressure, Cardiorespiratory Fitness, Cardiovascular Diseases, Pediatrics, Perinatology and Child Health, Waist circumference, Female, medicine.symptom, business, Brazil
Abstract: Background There is a lack of clarity as to which obesity parameters may be more important in the association between cardiorespiratory fitness (CRF) and cardiometabolic risk factors (CMRF). Aim To verify the mediating role of different obesity parameters on the association between CRF and CMRF in normal weight and overweight/obese children and adolescents. Methods This cross-sectional study comprised 999 children and adolescents (534 boys) aged 7-14 years from the south of Brazil. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR) and percentage of body fat were assessed. Participants were classified as normal weight, overweight and obese according to BMI. CRF was evaluated by the 6-minute run/walk test. . A continuous CMRF score was calculated by summing the Z-scores of the following variables: systolic and diastolic blood pressure, glucose, total cholesterol, high-density lipoprotein cholesterol and triglycerides. Data analysis was performed using partial correlation and linear regression models. Results BMI, WC, WHtR and percentage of body fat mediated the relationship between CRF and CMRF in overweight/obese boys and girls but not those of normal weight. Additionally, the percentage of the influence of each obesity parameter was 20% for BMI and WC, 16% for percentage of body fat and 18% for WHtR in girls. For boys, the mediation effect was 25% for BMI, 26% for WC, 28% for percentage of body fat and 25% for WHtR. Conclusion Adiposity plays a central role in CMRF; therefore, maintaining an adequate weight status should be an important objective of health-promoting programmes in early age. Abbreviations: CMRF, cardiometabolic risk factors; CRF, cardiorespiratory fitness; BMI. body mass index; HDL-c, high-density lipoprotein cholesterol, PROCESS PROESP-Br, Projeto Esporte Brasil; SPSS, Package for Social Sciences; TC, total cholesterol; TG, triglycerides; WC, waist circumference; WHtR, waist-to-height ratio; %BF, percentage of body fat.
Published: 2020

11. Metabolic risk is associated with sociodemographic characteristics in adolescents from both rural and urban regions from southern Brazil

Author: Sonimar de Souza, João Francisco de Castro Silveira, Kelin Cristina Marques, Anelise Reis Gaya, Silvia Isabel Rech Franke, Jane Dagmar Pollo Renner, James Philip Hobkirk, Sean Carroll, and Cézane Priscila Reuter
Subjects: Male, Metabolic Syndrome, Cross-Sectional Studies, Glucose, Adolescent, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Pediatrics, Perinatology and Child Health, Humans, Female, Child, Brazil
Abstract: Background The prevalence of several cardiovascular metabolic disorders are increasingly cause for concern in adolescents worldwide. Given the complex interrelations between metabolic risk (MR) and sociodemographic variables, the present study aims to examine the association between the presence of MR with sociodemographic characteristics (sex, skin color, residential area, and parental socioeconomic status) in adolescents from Southern Brazil. Methods Cross-sectional study conducted with 1,152 adolescents (507 males) aged between 12 and 17 years. MR was assessed using a continuous score (cMetS; sum of Z-scores of the following variables: waist circumference, systolic blood pressure (SBP), glucose, high-density lipoprotein cholesterol [HDL-C, inverse], triglycerides [TG], and estimated cardiorespiratory fitness [CRF, inverse]). Poisson regression was used to examine associations between sociodemographic variables with the dichotomized cMetS and separate metabolic variables. The results were expressed with prevalence ratios (PR) and 95% confidence intervals (CI). Results The presence of MR (evaluated by the cMetS) was observed in 8.7% of adolescents. Higher MR was less prevalent among non-white adolescents (PR: 0.96; 95% CI: 0.93; 0.99). Adolescents living in rural areas had a lower prevalence of the following metabolic variables; low HDL-C (PR: 0.95; 95% CI: 0.94; 0.97), elevated TG (PR: 0.95; 95% CI: 0.92; 0.99), elevated glucose (PR: 0.96; 95% CI: 0.95; 0.98), and low CRF levels (PR: 0.88; 95% CI: 0.85; 0.92). Whereas, SBP was higher in those living in rural areas (PR: 1.11; 95% CI: 1.05; 1.17). In girls, there was a higher prevalence of raised TG (PR: 1.06; 95% CI: 1.02; 1.10) and lower levels of CRF (PR: 1.20; 95% CI: 1.16; 1.24), but a lower prevalence of elevated glucose (PR: 0.97; 95% CI: 0.97; 0.99). Conclusion Higher MR prevalence was lower in those self-reporting non-white skin color and selected MR factors were less prevalent in those living in rural areas. The identification of groups at higher MR is important for early prevention and monitoring strategies for both Type 2 diabetes and later cardiovascular disease. Future studies should be conducted to assess the socio-cultural aspects of the relationships between MR and socio-cultural and lifestyle variables.
Published: 2022

12. Food Consumption is Associated with Hyperuricemia in Boys

Author: Leticia Borfe, Luiza Naujorks Reis, Jane Dagmar Pollo Renner, Silvia Isabel Rech Franke, Javier Brazo-Sayavera, Cézane Priscila Reuter, Caroline Brand, and Anelise Reis Gaya
Subjects: Male, 0301 basic medicine, Eating, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, School children, Hyperuricemia, Child, Body mass index, Índice de massa corporal, Age Factors, Up-Regulation, Blood pressure, Female, Estudantes, Cardiology and Cardiovascular Medicine, Adolescent, Risk Assessment, 03 medical and health sciences, Sex Factors, Insulin resistance, Environmental health, Internal Medicine, medicine, Humans, business.industry, Eating habits, nutritional and metabolic diseases, Feeding Behavior, medicine.disease, Obesity, Diet, Uric Acid, Cross-Sectional Studies, 030104 developmental biology, Ácido úrico, chemistry, Pressão arterial, Uric acid, Metabolic syndrome, business, Biomarkers, 030217 neurology & neurosurgery, Dyslipidemia, Hábitos alimentares
Abstract: Hyperuricemia is related to health issues among children and adolescents, once the uric acid concentration is associated with metabolic syndrome, hypertension, insulin resistance, obesity, and dyslipidemia. However, few studies are addressing uric acid levels and food uptake in this age group. Aim To verify the association between food consumption and uric acid in children and adolescents. Methods This is a cross-sectional study developed with 2335 children and adolescents of both genders aged 6–17 years old. Blood collection was performed after 12 h of fasting. Uric acid values were classifed according to tertiles, in which the highest tertile was considered as hyperuricemia. Food consumption was evaluated by weekly consumption frequency questionnaire. Pearson correlation and logistic binary regressions were used for statistical analysis. Models were adjusted for age, systolic blood pressure, body mass index (BMI), and skin color/ethnicity. Results It was found an association between red meat consumption and hyperuricemia only in boys in the crude model (OR=1.56; 95% CI 1.12; 2.18). Also, there was an association between pasta (OR=1.52; 95% CI 1.11; 2.10) with hyperuricemia in boys, when adjusted age, systolic blood pressure, BMI, and skin color/ethnicity. Conclusion The knowledge of food patterns which are predisposing factors for the increase in serum uric acid levels is important for the implementation of strategies and public health policies for health promotion among children and adolescents.
Published: 2020

13. Metabolic risk associated with liver enzymes, uric acid, and hemoglobin in adolescents

Author: Cézane Priscila Reuter, Rodrigo Antunes Lima, Silvia Isabel Rech Franke, Sonimar de Souza, Karin A. Pfeiffer, Jane Dagmar Pollo Renner, Elza Daniel de Mello, Anelise Reis Gaya, and Lars Bo Andersen
Subjects: Male, Risk, medicine.medical_specialty, Waist, Adolescent, Population, Gastroenterology, Hemoglobins, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, 030225 pediatrics, Internal medicine, Odds Ratio, medicine, Humans, Aspartate Aminotransferases, Child, education, Adolescentes, Triglycerides, Metabolismo, Metabolic Syndrome, education.field_of_study, business.industry, Area under the curve, Alanine Transaminase, Cardiorespiratory fitness, Odds ratio, Uric Acid, Cross-Sectional Studies, Blood pressure, Obesidade, Cardiorespiratory Fitness, Liver, chemistry, Pediatrics, Perinatology and Child Health, Uric acid, Female, Hemoglobin, Lipoproteins, HDL, business, Brazil, 030217 neurology & neurosurgery
Abstract: BACKGROUND The associations of renal, hepatic, and hematologic markers with metabolic risk (MR) have already been shown in adolescents. However, it is still controversial which marker best predicts metabolic changes in youth. The aim of this study was to verify the association of MR with alanine aminotransferase (ALT), aspartate aminotransferase (AST), uric acid, and hemoglobin (Hb) in adolescents. METHODS We evaluated 1713 Brazilian adolescents aged 10 to 17 years. MR was calculated using a continuous metabolic risk score, including the sum of Z-scores of waist circumference, systolic blood pressure, fasting glucose, high-density lipoproteins, triglycerides, and cardiorespiratory fitness. Cutoff points were set for MR prediction for five metabolic components (ALT, AST, AST/ALT ratio, uric acid, and Hb). RESULTS MR was strongly associated with increased uric acid (odds ratio [OR]: 2.50; 95% confidence interval [CI]: 1.74-3.59), ALT (OR: 2.64; 95% CI: 1.63-4.27), and AST levels (OR: 2.53; 95% CI: 1.24-5.18). Uric acid was shown to be the best predictor for MR (sensitivity: 55.79%; specificity: 61.35%; area under the curve: 0.616). CONCLUSION Elevated hepatic, renal, and hematological markers were associated with MR in adolescents, especially ALT, AST, and uric acid levels. IMPACT Elevated hepatic, renal, and hematological markers were associated with metabolic risk in adolescents, especially ALT, AST, and uric acid levels. It is still controversial which marker best predicts metabolic changes in adolescents. In addition, association of Hb with metabolic risk is under-studied in this population. It is important to further investigate the relationship between elevated Hb and hepatic markers, since there are key aspects not addressed yet. Our results highlight the importance of creating public health policies aimed to child and adolescent population, to prevention of metabolic disorders from an early age.
Published: 2020

14. Effects and prevalence of responders after a multicomponent intervention on cardiometabolic risk factors in children and adolescents with overweight/obesity: Action for health study

Author: Maria Luisa Félix Pessoa, Caroline Brand, Anelise Reis Gaya, Eduardo Lusa Cadore, Adroaldo Cezar Araujo Gaya, Clarice Martins, Vanilson Batista Lemes, Arieli Fernandes Dias, and Jorge Mota
Subjects: Male, Parents, Pediatric Obesity, Adolescent, Crianças, 030209 endocrinology & metabolism, Physical Therapy, Sports Therapy and Rehabilitation, Exercício físico, Saúde, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Environmental health, Intervention (counseling), Body Fat Distribution, Homeostasis, Humans, Medicine, Orthopedics and Sports Medicine, Aspartate Aminotransferases, Obesity, Child, Exercise, Adolescentes, Triglycerides, Cardiometabolic risk, business.industry, Cholesterol, HDL, Cardiometabolic health, Overweight obesity, Social Support, Physical exercise, Alanine Transaminase, Cholesterol, LDL, 030229 sport sciences, Overweight, Cholesterol, Obesidade, Action (philosophy), Youth, Female, Diet, Healthy, Insulin Resistance, business
Abstract: This study aimed to verify the effect of a multicomponent intervention on cardiometabolic risk factors (CMRF), and to determine the prevalence of responders on CMRF among children and adolescents with overweight/ obesity. This is a quasi-experimental study, developed with 35 children and adolescents with overweight/ obesity (control group (CG) = 18; intervention group (IG) = 17), aged between 7 and 13 years. Participants in IG underwent a multicomponent intervention for 12 weeks. The following variables were evaluated: anthropometric measures, maturational stages and CMRF (body fatness, HOMA-IR, triglycerides, high-density and low-density lipoprotein) (HDL-C, LDL-C), total cholesterol (TC), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and AST/ALT ratio. Mixed analysis of variance and the prevalence of responders were used for statistical analysis. There was a significant time x group interaction on body fatness (p < 0.001), HOMA-IR (p = 0.01), HDL-C (p < 0.001), LDL-C (p = 0.009) and TC (p < 0.001). The prevalence of responders for CMRF in IG and CG was respectively: body fatness (47%; 0%; p = 0.04), HOMA-IR (58.8%; 16.6%; p = 0.04); triglycerides (17.6%; 5.5%; p = 0.31); HDL-C (76.4%; 5.5%; p = 0.01), LDL-C (35.3%; 5%; p = 0.08), TC (64.7%; 5%; p = 0.01), AST (5.8%; 0%; p = 0.87), ALT (29.4%; 11.1%; p = 0.24) and AST/ALT ratio (24.4%; 22.2%; p = 0.67). Multicomponent intervention induced positive changes on CMRF along with a higher prevalence of positive adaptations in IG than the CG in some of the cardiometabolic outcomes assessed.
Published: 2020

15. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

Author: Maryam Sharafkhah, Emanuel Zitt, Majid Ezzati, Luxia Zhang, Young-Ho Khang, Ellina Rakhimova, Kairit Mikkel, Tiina Vlasoff, Eruke E. Egbagbe, Sidsel Graff-Iversen, Ilona Nenko, Magdalena Klimek, Mathilde Savy, Sanjib Kumar Sharma, Alfonso Siani, Luís Lopes, Vanina Bongard, Gregor Jurak, Jacqueline F. Price, Christina-Paulina Lambrinou, Maria Lc Iurilli, Rainford J. Wilks, Bontha V. Babu, Fereidoun Azizi, Harunobu Nakamura, Marialaura Bonaccio, Angela Döring, Zhenyu Zhang, Naser Ahmadi, Jolanta Słowikowska-Hilczer, Ana Paula Carlos Cândido, Clive Osmond, Thirunavukkarasu Sathish, Robert J. Adams, Themistoklis Tzotzas, Reina Engle-Stone, Atul Trivedi, Shoichiro Tsugane, Niels Møller, Jorge Bezerra, Dénes Molnár, Muhammad Fadhli Mohd Yusoff, Badreya Al-Lahou, J. Jaime Miranda, Bahram Mohajer, Sigmund A. Anderssen, Lital Keinan Boker, Eero Kajantie, Martin Gulliford, Maties Torrent, Sumit Bharadwaj, Toshiharu Ninomiya, Zbigniew Gaciong, Nayu Ikeda, Li Juan Wu, Adrian Richter, Licia Iacoviello, Marc J. Gunter, Wenbin Wei, Norsyamlina Che Abdul Rahim, Eman Aly, Ambady Ramachandran, Nils Lehmann, Soile E. Puhakka, Giovanni Veronesi, Hongsheng Bi, Eiji Oda, Jia Li Duan, Per Tynelius, José María Huerta, Janne Schurmann Tolstrup, Rodrigo M. Carrillo-Larco, Rosangela Fernandes Lucena Batista, Victoria E Soto-Rojas, Hanno Ulmer, Shukri F. Mohamed, Anthony Kafatos, Suyeon Park, Mohsen Ibrahim, Hamed Pouraram, Bin Zhou, May Soe Aung, Lars Bo Andersen, Erfan Ghasemi, René Charles Sylva, Himanshu K. Chaturvedi, Luc Dauchet, Ahmad Ali Zainuddin, Angela Chetrit, Dan Zhu, Valérie Deschamps, Ko Ko Zaw, Peter Vollenweider, Tomas Vega, Yves Martin-Prével, Mahfuzar Rahman, Dorja Vočanec, Roman Topor-Madry, Vinay Nangia, Herculina S. Kruger, Asher Fawwad, Emily Sonestedt, Elena Pahomova, Aleksander Giwercman, Elżbieta Dziankowska-Zaborszczyk, Cecilia Björkelund, Tatjana Hejgaard, Maria Puiu, Maria Benedetta Donati, Andrew Wong, Carlos P. Boissonnet, Santosh K. Bhargava, Patrick Kolsteren, Dermot O'Reilly, Bahareh Kheiri, Wolfgang Kratzer, Susanne R. de Rooij, H. Bas Bueno-de-Mesquita, Günther Fink, José R. Banegas, Michele Monroy-Valle, Drude Molbo, Mahmudur Rahman, Hynek Pikhart, Rafael N. Pichardo, Massimo Salvetti, Hui Cai, Sarah Filippi, Georg Posch, Hung-Kwan So, Yonghua Hu, Katsuyasu Kouda, Joana Carvalho, Gailute Bernotiene, Hannu Uusitalo, Thein Thein Htay, Felix Kaducu, Maigeng Zhou, Lars Ängquist, Thi Tuyet-Hanh Tran, Charles Lunogelo, Michel Joffres, Sabina Zambon, Ronald D. Gregor, Vayia Rarra, Seyed Mohammad Hashemi-Shahri, Loreto Santa Marina, Galina Obreja, Rudolf Kaaks, Aya Mostafa, Maria do Carmo Franco, Beata Gurzkowska, Chien-Jen Chen, Marie Moitry, Nizal Sarrafzadegan, Xiangjun Wang, Diego Giulliano Destro Christofaro, Imperia Brajkovich, Fangfang Chen, Francesco Panza, Ling Yang, Holly E. Syddall, Cecily Kelleher, Michael Tornaritis, Ningli Wang, Lutgarde Thijs, Marjolein Visser, Angelika Schaffrath Rosario, María José Tormo, Jostein Steene-Johannessen, Norbert Amougou, Emmanuella Magriplis, Mar Alvarez-Pedrerol, Jingli Gao, Stig E. Bojesen, Giuseppe Grosso, Seongjun Ha, Lauren Lissner, Mikhail Benet, Anastasia Markaki, Sanjay Rampal, Antônio Augusto Moura da Silva, Maria Lorenza Muiesan, Angelique Chan, Yvonne T. van der Schouw, Annamari Lundqvist, Philippe Amouyel, Kristyna Zejglicova, Charalambos Hadjigeorgiou, João Breda, Jørgen Meisfjord, Fatima Zahra Laamiri, Carl Lachat, Kai-Uwe Saum, Vilma Irazola, Leng Huat Foo, Óscar Lopes, Dickman Gareta, Flavio Nervi, Imre Janszky, Ruzena Kubinova, Terho Lehtimäki, Mario V. Capanzana, Moyses Szklo, Ramfis Nieto-Martínez, Viswanathan Mohan, Shuohua Chen, Arvind Pandey, Luigi Palmieri, Roya Kelishadi, Srinivasan Kannan, Jie Mi, Robert Beaglehole, Liliana Dacica, Jyrki K. Virtanen, Mohan Deepa, Peter Ueda, Isti Ilmiati Fujiati, Hermann Pohlabeln, Morten Sodemann, Jytte Halkjær, Zbigniew Kułaga, Sophie Visvikis-Siest, Farshad Farzadfar, Mohsen Azimi-Nezhad, Henry Völzke, Karolina Milkowska, Zahra Mohammadi, Belgin Ünal, Magda Gasull, George S. Stergiou, Marshall K. Tulloch-Reid, Seppo Koskinen, James E. Bennett, Marcela González-Gross, Virginija Dulskiene, Idris Guessous, Assembekov Batyrbek, Kamarul Imran Musa, Jeannette Lee, Josep Redon, Bihungum Bista, Luisa M Macieira, Johan Sundström, Andres Metspalu, Lariane M Ono, Flora A. Ukoli, Salar Rahimikazerooni, Andrea Gualtieri, Trevor S. Ferguson, Félicité Tchibindat, Eliza Cinteza, Ha Tp Do, Tajana Zeljkovic Vrkic, Tuyen D Le, Alison J. Hayes, Abdul Basit, Chandini Nekkantti, Teresa Norat, Eunice Ugel, Gulmira Aitmurzaeva, Mariachiara Di Cesare, Abdul Hamid Zargar, Vincenzo Solfrizzi, Garry L. Jennings, Aline Meirhaeghe, Kaare Christensen, Päivi Mäki, Xu Lin, Ali Esmaeili, Joanna Baran, Aneta Grajda, Renata Cifkova, Alexandre C. Pereira, Martin Bobak, Iuliia A Rusakova, Keiu Nelis, Damian K Francis, Guansheng Ma, Axel C. Carlsson, Alejandro Diaz, Alireza Ansari-Moghaddam, N Capkova, Zumin Shi, Maria Turley, Imelda A. Agdeppa, Helena I. S. Nogueira, Marcia Scazufca, Katharina Maruszczak, Natascia Rinaldo, Paulo A. Lotufo, Nuno Lunet, Thor Aspelund, Caroline H.D. Fall, Antonio Cabrera de León, Ahmad Faudzi Yusoff, Holger Theobald, Beatriz D'Agord Schaan, Pedro Marques-Vidal, William A. Neal, Mihai Gafencu, Tandi E. Matsha, Ana B. Crujeiras, Ahmad Reza Dorosty, Alain Morejon, Weili Yan, Dominique Hange, Bekbolat Zholdin, Frédéric Gottrand, Jorge Mota, Jana Námešná, Stevo Popovic, Louise Eriksen, Line Lund Kårhus, Cihangir Erem, Juergen Breckenkamp, Mathilde Kersting, Yi Song, Martin McKee, Aleksandra Gomula, Rafaela Rosário, Enzo Manzato, S. Goya Wannamethee, Sounnia Mediene Benchekor, Azim Nejatizadeh, Krishna Kumar Aryal, Juan P. González-Rivas, Vedrana Sember, Stephen T. McGarvey, Jukka T. Salonen, Patrick Pasquet, Patricia Varona-Pérez, Amelia C. Crampin, Ramin Heshmat, Violeta Iotova, Juvenal Soares Dias-da-Costa, Oye Gureje, Aletta E. Schutte, João Luiz Bastos, Anelise Reis Gaya, Konrad Jamrozik, Dalia Luksiene, Amina Barkat, Maria Paula Santos, José Camolas, Azli Baharudin, Diego Vanuzzo, Doris Stöckl, Rosalynn Siantar, Jouko Saramies, Albertino Damasceno, Davood Khalili, Simona Bo, Martina Müller-Nurasyid, Dominique Cottel, Markku Peltonen, Fikru Tullu, Ana Isabel Rito, Angélica Ochoa-Avilés, Annette J. Dobson, Christopher T. Cowell, Charumathi Sabanayagam, Rildo de Souza Wanderley Júnior, Oanh T. H. Trinh, Farahnaz Joukar, Mostafa K. Mohamed, Mostafa Qorbani, Jeongseon Kim, Helmut Schröder, Machi Suka, Natasja M. van Schoor, Jussi Kauhanen, Teresa Haugsgjerd, Goodarz Danaei, M. Fernanda Lima-Costa, Yong Tao, Elisabetta L. Romeo, Grazyna Jasienska, Victor Guillermo Sequera, Kazem Mohammad, Yanina Zócalo, Fernanda Cunha Soares, Jianfeng Wu, Mohammad Esmaeel Motlagh, María Elena Díaz-Sánchez, Monika Zuziak, Eldridge Ferrer, Anette Varbo, Leila Beltrami Moreira, Jeremy M. Jacobs, Kenneth James, Elena Sacchini, Pascal Bovet, Mahboubeh Parsaeian, Tania Lopez, Ya Xing Wang, Wojciech Drygas, Jody C Miller, Svetlana A. Shalnova, Maria Elisa Zapata, Chung T Nguyen, Nimmathota Arlappa, Edwige Landais, Thorkild I. A. Sørensen, Jeannette Klimont, Amirabbas Momenan, Erik J. Timmermans, Mari-Liis Tammesoo, Jost B. Jonas, Stefania Toselli, Maria Teresa Anselmo Olinto, Bahman Cheraghian, Kouamelan Doua, Esteban Carmuega, Marjeta Mišigoj-Duraković, Bo Werner, M. Arfan Ikram, Breige A. McNulty, Christa Meisinger, Clara Homs, Namuna Shrestha, Alina Kerimkulova, Youcef Laid, Claes Ohlsson, Alicia Matijasevich, Alison J Price, Ala'a Alkerwi, Kristine H. Allin, Lorenza Pilotto, Mohannad Al Nsour, Ingunn Holden Bergh, Marianna Noale, Heba Fouad, Vilnis Dzerve, Novie O. Younger-Coleman, Peter Willeit, Andrea R. V. R. Horimoto, Freda Pitakaka, Habiba Ben Romdhane, Savvas C. Savva, Rajeev Gupta, Jennifer Servais, Cristina Padez, Sarah P. Garnett, Maria del Cristo Rodriguez-Perez, Michala Lustigová, Tien Yin Wong, Rosa Haghshenas, Jonathan Giovannelli, Christina Howitt, Marleen E. Hendriks, Fadia AlBuhairan, Huashuai Chen, Gretchen A Stevens, Luís B. Sardinha, David Goltzman, Jenny M. Kindblom, Karina Mary de Paiva, Yousef Khader, Eric Monterrubio-Flores, Rajendra Pradeepa, Yi-Ting Lin, Martin Neovius, Juan Francisco Miquel, Ellis Owusu-Dabo, Anil Poudyal, Marzieh Katibeh, Tanja Stocks, Veronica Mocanu, Ulla Roggenbuck, Robespierre Ribeiro, Gabriele Eiben, Mary Simon, Christine Cameron, Hamid Hakimi, Kamel Ajlouni, Jakub Stokwiszewski, Iulia Jurca Simina, Pietro Amedeo Modesti, Frederick C. W. Wu, Peter Kristensen, Charles Mondo, Felix Gutzwiller, Mariana Sbaraini, Martijn Huisman, Betina H. Thuesen, Queenie Chan, Antonisamy Belavendra, Artur Mazur, Ulf Ekelund, Laura A. Rodríguez-Villamizar, Marcos André Moura-dos-Santos, Jean Ferrières, Farhad Zamani, Shina Avi, Yves Kameli, Luis Paulo Gomes Mascarenhas, Aluísio J D Barros, Thomas Meinertz Dantoft, Hossein Poustchi, Farid Najafi, Giovanni de Gaetano, Azaliia M Tuliakova, Vera Lanska, Tint Swe Latt, Matthias Bopp, Abbas Rezaianzadeh, Rod Jackson, Johan Van der Heyden, Reecha Sofat, Koen Van Herck, Allan G. Hill, Con Burns, Emanuela Pettenuzzo, Ming-Dong Wang, Stela McLachlan, Ulrike Gehring, Ranko Stevanovic, Nagalla Balakrishna, Lekhraj Rampal, Marjolijn C. E. Bragt, Saeid Eslami, Napoleón Pérez-Farinós, G. K. Mini, Viktoria Anna Kovacs, Rosemarie Martin, Nahla Hwalla, Wei Zheng, Hoang Van Minh, Edward D Janus, Laetitia Huiart, Farhad Pourfarzi, Sudha Ramachandra Rao, Fred Paccaud, Marcia Makdisse, Aye Aye Sein, Enrique Gutiérrez-González, Yang Yang, Anneke Blokstra, Henrike Galenkamp, Jaume Marrugat, Nazan Yardim, Wan Nazaimoon Wan Mohamud, Jesús Ibarluzea, Julio Zuñiga Cisneros, Laura Lauria, Argyro Karakosta, Dragana P Jovic, Jun Hata, Elio Riboli, Piotr Bandosz, Xun Tang, Parvina Mukhtorova, Jean Dallongeville, Jean-Bernard Ruidavets, Anne Tjønneland, Guillermo Frontera, Rahul Malhotra, Thomas Ferrao, Aleksandra Piwońska, Dusan Grafnetter, Mette Rasmussen, Daniel Weghuber, Sherali Rakhmatulloev, Martine Vrijheid, Johann Willeit, Motahareh Kheradmand, Małgorzata Mossakowska, Lechaba Tshepo, Dongfeng Gu, Hyeon Chang Kim, Vilmundur Gudnason, Maria Forsner, Peter Bjerregaard, Leon A. Simons, Rachael McLean, Japhet Killewo, Ramón Suárez-Medina, Y Nikitin, Eng Joo Tan, Jean Claude Mbanya, Aroor Bhagyalaxmi, Renata Kuciene, Kairat Davletov, Jose Eugenio Lozano, Afshin Ostovar, Niloofar Peykari, Guy De Backer, Soheir H Ahmed, Nicholas J. Wareham, Sai Yin Ho, Constanta Huidumac Petrescu, Maria Hassapidou, Iris Pigeot, Myriam Galfo, Susana Cararo Confortin, Blanca Sandra Ruiz-Betancourt, W. M. Monique Verschuren, Catterina Ferreccio, Fabio Galvano, Leila Houti, Daniel Bia, Annika Rosengren, Marcin Rutkowski, Biruta Velika, Joana Araújo, Fernando Rigo, Angela Spinelli, Scott B. McLean, Shirin Djalalinia, Marie Kunešová, Boban Mugoša, Sania Nishtar, Mangesh S. Pednekar, Shahla AlDhukair, Helle-Mai Loit, Antonis Zampelas, Altan Onat, Maciej Banach, Shohreh Naderimagham, Hajer Aounallah-Skhiri, Maja Bæksgaard Jørgensen, Yin Guo, Ewelina Czenczek-Lewandowska, Parasmani Dasgupta, Elvis Oa Wambiya, Inge Huybrechts, Raimund Erbel, Jari Jokelainen, Ana P. Ortiz, Stefan Kiechl, Emmanuel Cohen, Caleb Ochimana, Shynar Abdrakhmanova, Laura Censi, Iqbal Bata, Geetha R Menon, Snehalatha Chamukuttan, Pedro Plans-Rubio, Domenico Palli, Ana Azevedo, Slawomir Koziel, Benoît Salanave, Parinaz Mehdipour, Shu Ti Chiou, Lela Sturua, Lubica Ticha, Felipe Vogt Cureau, Jin Soo Moon, Ming-Hui Zhao, Urho M. Kujala, Nathalie Michels, Ertugrul Celikcan, Jaakko Tuomilehto, Judith Benedics, Tobias F. Rinke de Wit, Agnès Le Port, Reza Homayounfar, Andrea Rodriguez-Martinez, Tai Hing Lam, Yn-Tz Sung, Jürgen König, Kodavanti Mallikharjuna Rao, Hazzaa M. Al-Hazzaa, Karen Morgan, Bogdan Wojtyniak, Cynthia M. Pérez, Ilse Khouw, Manoli Garcia-de-la-Hera, Dong Wook Shin, Genc Burazeri, Ausra Petrauskiene, Charles Sossa Jérome, Kenisha Russell Jonsson, José Boggia, Daniela Galeone, Alice Bonilla-Vargas, Han Cg Kemper, Rahman Shiri, Stefaan Demarest, Else Karin Grøholt, San-Lin You, Adelheid Weber, Juha Auvinen, Aida Pilav, Sibel Gogen, Suzanne N Morin, Wan Mohamad Wan Bebakar, Viviane Cunha Cardoso, Kavumpurathu Raman Thankappan, Hana Zamrazilová, Frank Claessens, Karien Stronks, Helen Gonçalves, Tahir Aris, Luis Revilla, Sérgio Viana Peixoto, Zhamilya Battakova, Jing Liu, Eliza Markidou Ioannidou, Leticia Hernandez Cadena, Priscilla Duboz, Sandjaja, Tiina Laatikainen, Rafel Ramos, Sareh Eghtesad, Judith Simons, Orn Olafsson, E. Shyong Tai, Louise A. Baur, Nihal Thomas, Aung Soe Htet, Bente Sparboe-Nilsen, Paul Elliott, Soon-Woo Park, Angel R. Gonzalez, Ying-Wei Wang, Rob M. van Dam, Ryutaro Ohtsuka, Ludmila Sevcikova, Suhaila Abdul Ghaffar, Lynell V Maniego, Fariborz Mansour-Ghanaei, Maria Dorobantu, Giovanni Viegi, Xiaoguang Yang, Honor Bixby, Prakash C. Gupta, Ofra Kalter-Leibovici, Eugene Sobngwi, Ričardas Radišauskas, Jurate Medzioniene, Roy A Wong-McClure, Kim F. Michaelsen, Antonia Trichopoulou, Tania Tello, Francesco Branca, Johanna Gunnlaugsdottir, Els Clays, Wei-Yen Lim, Suzanne C. Ho, Toomas Veidebaum, Rebecca Goldsmith, Margot González-León, Matthias Nauck, Alibek Mereke, Marta Buoncristiano, Jakob Tarp, Rosalba Rojas-Martínez, Maya Tanrygulyyeva, Reza Malekzadeh, Abdonas Tamosiunas, Dimitrios Poulimeneas, Pedro Ordunez, Isabelle Herter-Aeberli, Khanh Le Nguyen Bao, Anne Juolevi, Vassilis Zafiropulos, Emanuela Gualdi-Russo, Jordi Sunyer, Manu Raj, Chaoqiang Jiang, Sofia Malyutina, Efthymios Kapantais, Maria Lazo-Porras, Maung Maung Than Htike, Michael Hobbs, Ranjit Mohan Anjana, Merike Liivak, Johan G. Eriksson, Margarita Samoutian, Andreia N. Pizarro, Mohammed Rasoul Tarawneh, Jean Woo, Kaspar Staub, Maria Teresa Menzano, Mojtaba Farjam, Adroaldo Cesar Araujo Gaya, Mohammad El-khateeb, Zulfiqar A Bhutta, Mukharram M. Bikbov, Hsien-Ho Lin, Oscar Noboa, Thomas Waldhör, Garry Brian, Simona Costanzo, Frank Tanser, Nor Azwany Yaacob, Michelle Cilia, Ivo Rakovac, Bill Stavreski, Ioannis Pagkalos, Ivan Pećin, Carlo M. Barbagallo, Abla M. Sibai, Yuna He, Matsuda Fumihiko, Bharathi Viswanathan, Ali Reza Safarpour, Wei Cheng Lo, Abdullatif Husseini, Jiang He, Liv Elin Torheim, Nipa Rojroongwasinkul, Aicha Soumare, Astrid Petersmann, Tomasz Grodzicki, Davide Noto, Panayiotis K. Yiallouros, Kelias P. Msyamboza, William R. Tebar, Yingfeng Zheng, Eha Nurk, Bhawesh Koirala, Ana Jelakovic, Suhad Bahijri, Freja B Kampmann, Qi Sheng You, Marika Ferrari, María-Elena González-Villalpando, Aline Wagner, Olfa Saidi, Anwar Batieha, Eduardo Capuano, Coimbatore Subramaniam Shanthirani, Dong Wook Kim, Albina A Fakhretdinova, Tom Wilsgaard, Maria Avdicova, Moesijanti Soekatri, Chiara Donfrancesco, Salim Mohanna, Paola Russo, Uruwan Yamborisut, Rafael dos Santos Henrique, Martin Nankap, Allan Linneberg, Khairil Si-Ramlee, Kirsten Mehlig, Christina Mavrogianni, Raluca Pop, Lèlita Santos, Graziella Bruno, Valentina Peterkova, Iná S. Santos, Georg Lappas, Alberto Palloni, Malay K. Mridha, Andrzej Pajak, Marta García-Solano, Stefaan De Henauw, Daniel Ferrante, Rute Santos, Anders Grøntved, Lucjan Szponar, Mihaela Vladulescu, Chien-An Sun, Jan A. Staessen, Paula Duarte de Oliveira, Norazizah Ibrahim Wong, Maria Nordendahl, Elaine M. Dennison, Jeonghee Lee, Diego Salmerón, Ida Maria Schmidt, Gao Pei, Noushin Mohammadifard, Igor Spiroski, Fernando Rodríguez-Artalejo, Xu Ma, Elin Pettersen Sørgjerd, Valéria Regecová, Cláudia S. Minderico, Johanna A. Otero, Jamila Abubakar Garba, Vesselka Duleva, Rui Ornelas, Ilpo Huhtaniemi, Cesar G. Victora, Lijuan Liu, Rody G. Sy, Mahmood Moosazadeh, Ali Ahmadi, Antonio Pedro Graça, Natalia Nowak-Szczepanska, Miao Li Chee, Michael Sjöström, Charles Agyemang, Shiqi Zhen, Xiu-Hua Guo, Pawel Kurjata, Jardena J. Puder, Mehrdad Azmin, Neil Murphy, Kaosar Afsana, Alireza Sadjadi, Johanna M. Geleijnse, Prashant Mathur, Elysée Claude Bika Lele, Raphael Mendes Ritti-Dias, Yannis Manios, Majid Shirani, Rosemary B. Duda, Liis Nelis, Jurate Klumbiene, Zhengming Chen, Wichai Aekplakorn, Alun Evans, Andrzej Wiecek, Lars Lind, Denise Eldemire-Shearer, Bernardo L. Horta, Macia Enguerran, Seyed Rasoul Zakavi, Daniel Fernández-Bergés, Kumiko Ohara, Ursula Kiechl-Kohlendorfer, Hermann Brenner, Przemyslaw Slusarczyk, Espen Bjertness, Jutta Stieber, Augusto Di Castelnuovo, Joel G. R. Roy, Aryeh D. Stein, Ruth Frikke-Schmidt, Vera Musil, Amaneh Shayanrad, Marcel Goldberg, Ramon O. Jimenez, Mohammad Reza Fattahi, Jolanda Hyska, Amir Houshang Mehrparvar, Elin Kolle, Mohamed Bamoshmoosh, Michelle Holdsworth, Felipe F. Casanueva, Børge G. Nordestgaard, Niels Wedderkopp, Eva Corpeleijn, Elias F. Gudmundsson, Antonio Mistretta, Daniel Lemogoum, Larissa Pruner Marques, Slavica Sović, Olli T. Raitakari, Marco Aurélio Peres, Alexandra Cucu, Gregorio Varela-Moreiras, Janine Clarke, Andrea Gazzinelli, Mieczysław Litwin, Sara Schramm, Xenophon Theodoridis, Harshpal Singh Sachdev, Mohammad Reza Mirjalili, Dimitrios Papandreou, Peter T. Katzmarzyk, Benjamin Acosta-Cazares, Ben Schöttker, Prabhdeep Kaur, Norlaila Mustafa, Shariq Rashid Masoodi, Sadaf G. Sepanlou, Adolfo Rubinstein, Francis Delpeuch, Julianne Williams, Abbas Dehghan, Leanne M. Riley, Heloisa Bettiol, Gabriele Nagel, Ellisiv B. Mathiesen, Ekaterina Stoyanova, Alisha N. Wade, Zhamyila Usupova, Arnaud Chiolero, Oonagh Markey, Jacqueline Ramke, Elena Bogova, Niveen M E Abu-Rmeileh, Nguyen D Nguyen, Tomasz Zdrojewski, Marjo-Riitta Järvelin, Jose Sanchez-Abanto, Rômulo Araújo Fernandes, Lourdes Ribas-Barba, Nalan Uysal, Mohamad Hasnan Ahmad, Krista Fischer, Maria Wany Louzada Strufaldi, Ramiro Guerrero, Farnam Mohebi, Tran Quoc Bao, Flávio Danni Fuchs, Salim Berkinbayev, Enisa Kujundzic, Sari Voutilainen, Farzad Hadaegh, Robert Lundqvist, Saeid Safiri, Iraj Mohebbi, George Luiz Lins Machado-Coelho, Annette Peters, Gonzalo Valdivia, Magdalena Korzycka, Rajiv T Erasmus, Masanori Iwasaki, Charmaine A. Duante, Sheikh Mohammed Shariful Islam, Quang Ngoc La, Ricky Eddie, Petra Rust, Daniela Rodrigues, Dirk De Bacquer, Karen Sparrenberger, Agneta Sjöberg, Thet Thet Mu, Katarzyna Dereń, Cora L. Craig, Jorge Motta, Janina Petkeviciene, Boyd Swinburn, Paibul Suriyawongpaisal, Visnja Djordjic, Ramón Alberto Rascón-Pacheco, Pradeep Joshi, Daan Kromhout, Marius B. Bjertness, Stefano Marventano, Juel Jarani, Alireza Khosravi, Eva Martos, David De Ridder, Lizzy M. Brewster, Nico Dragano, Liam Smeeth, Kenji Shibuya, Emma Ruiz Moreno, Hashem Jaddou, Grzegorz Sobek, Dimitrios Trichopoulos, Marvin Cervantes-Loaiza, Abu Am Hanif, Elaine M. Murtagh, Carlos A. Aguilar-Salinas, Graziella D'Arrigo, Kyungwon Oh, Heiner Boeing, Regina Heidinger-Felso, André Luiz Sena Guimarães, Balkish M. Naidu, Avula Laxmaiah, Ana M. B. Menezes, Marie Eliasen, Francesco Pistelli, Yuan He, Dusko Bjelica, José A. Casajús, Guang Ning, Lutgart Braeckman, Dirk Vanderschueren, Jochanan Stessman, Ivana Radic, Yi Zeng, Hans Concin, Damaskini Valvi, Sari Hantunen, Catherine Kyobutungi, Diego Augusto Santos Silva, Wenhua Zhao, Sok King Ong, Anne W. Taylor, Iraj Nabipour, Justyna Godos, Cyrus Cooper, Mattias Johansson, Samuel C. Dumith, Magdalena Muc, Sabine Schipf, Idowu O Senbanjo, Jim Mann, Rajaa Al-Raddadi, Yih Chung Tham, Kay-Tee Khaw, Joseph Cacciottolo, Ana Henriques, Sahar Saeedi Moghaddam, Reza Mohammadpourhodki, Bernhard O. Boehm, Songhomitra Panda-Jonas, Iveta Pudule, Elisabete Ramos, Lacramioara Aurelia Brinduse, Paul H. Lee, Terence W O'Neill, Javad Aghazadeh-Attari, Margus Punab, Bojan Jelaković, Camilla T. Damsgaard, Takafumi Ishida, Ekaterina Chikova-Iscener, Mirjam M. Heinen, Tazeen H. Jafar, Semánová Csilla, Constance Schultsz, Santiago F. Gomez, Raija Korpelainen, Edward W. Gregg, Laura Gutierrez, Pierre Traissac, Victor M. Herrera, Aristides M. Machado-Rodrigues, Fatemeh Malekzadeh, Shouling Wu, Jennifer L. Baker, Clicerio González-Villalpando, Eleonora d'Orsi, Irene G. M. van Valkengoed, Anna Fijałkowska, Wen-Harn Pan, Gregor Starc, Meghnath Dhimal, Murat Topbaş, George Moschonis, Robert Eggertsen, Abdullah Alkandari, Quang Ngoc Nguyen, Janette Walton, Elnaz Faramarzi, Saeed Dastgiri, Lien Braeckevelt, Nasheeta Peer, Radka Taxová Braunerová, Mohamed M. Ali, Steiner Krokstad, Harald Geiger, Morteza Shamshirgaran, Lela Shengelia, María Ángeles Dal Re Saavedra, Silvana Donoso, Khem Bahadur Karki, Timothy J. Key, Maria G. Grammatikopoulou, Susana Vale, Felix K. Assah, Juan A Rivera, Peter H. Whincup, Oana-Florentina Gheorghe-Fronea, Cassiano Ricardo Rech, Paul Ferdinand M. Reganit, Rachakulla Hari Kumar, Jaakko Mursu, Luis A. Moreno, Glen Gironella, Jelena Kos, Tilema Cama, Haakon E. Meyer, Jun Ma, Raphael E. Arku, Ziad Abdeen, Dianna J. Magliano, Jitendra Jonnagaddala, Konstantinos Gkiouras, Paola Nardone, Alberto Barceló, Tomi-Pekka Tuomainen, Francesco Gianfagna, Stefania Maggi, Mohammad Hossein Somi, Behrooz Hamzeh, Miquel Porta, Vesna Jureša, Alexander D. Deev, David Faeh, Antonio Bernabe-Ortiz, Sirkka Keinänen-Kiukaanniemi, Ian Hambleton, Stefan Savin, Andre Pascal Kengne, R. Krishna Kumar, Kurt Widhalm, Marco M Ferrario, Parisa Amiri, Anjani Kumar Jha, Thamara Hubler Figueiró, Jana Kratenova, Claudia M. Hormiga, Maria Tsigga, Zivka Dika, Indrapal I. Meshram, Ei Ei K. Nang, Ian Rouse, Rusidah Selamat, Paul Korrovits, Grethe S. Tell, Julie Taylor, Anabela Mota-Pinto, Paolo Vineis, Kotsedi D Monyeki, Khuong Quynh Long, Frank J Rühli, Shelly R. McFarlane, Sara Santos Sanz, Edyta Łuszczki, Maria G. Stathopoulou, Tara Coppinger, Karin De Ridder, Lucie Viet, Anna Bugge, Mehdi Yaseri, Safiah Md Yusof, Sandra C. Fuchs, Muhammad Islam, Irfan Nuhoglu, Rui Providência, Bernard Maire, Leandra Abarca-Gómez, Sinead Brophy, Maria Ruiz-Castell, Daniela Pierannunzio, Cristina Taddei, Gowri Mahasampath, Gustavo Velasquez-Melendez, Hanna Tolonen, Sudhir Kowlessur, Bagher Larijani, Laura Torres-Collado, Susi Kriemler, Ali Akbar Shayesteh, Cynthia Robitaille, Jorge Escobedo-de la Peña, Yufang Bi, Chinh Nguyen Huu, Line Tang Møllehave, Vincent Jr DeGennaro, Noor Ani Ahmad, Anar Dushpanova, Agustinus Soemantri, Susana Sans, Ionela Pascanu, Gwenaëlle Le Coroller, Inger Ariansen, Kodanda R Kanala, Gert B. M. Mensink, Abhijit Sen, Sergej M. Ostojic, Hanan F. Abdul Rahim, Hélène Delisle, Francisco J. Félix-Redondo, Yadlapalli S. Kusuma, Michael Knoflach, Moein Yoosefi, Tanja G. M. Vrijkotte, Wolfgang Ahrens, Osvaldo Santos, Bethlehem D. Solomon, Erik Lykke Mortensen, Nikhil D. Patel, Reynaldo Martorell, Ching-Yu Cheng, Stine Schramm, Hana Shimizu-Furusawa, Jacek Jóźwiak, Radwan Qasrawi, Herman Borghs, Zhanna Kalmatayeva, Heidi Klakk, Akram Pourshams, Naomi S. Levitt, Son Thai Pham, Simona Giampaoli, Dong Zhao, Indah Suci Widyahening, Merete Osler, Paula Margozzini, Silvia Bel-Serrat, Dora Romaguera, Monira Alarouj, Winsome R. Parnell, Marloes Cardol, Giota Touloumi, Janice Luisa Lukrafka, Adela Chirita-Emandi, Maryam Kavousi, Sanja Musić Milanović, Jean-Michel Gaspoz, Jalila El Ati, Sauli Herrala, Liang Xu, Pilar Guallar-Castillón, Bee Koon Poh, Luis Serra-Majem, Jonathan E. Shaw, Belong Cho, Daphne Mirkopoulou, Salvador Villalpando, Yuki Fujita, Tiffany K. Gill, Nish Chaturvedi, Erkin M. Mirrakhimov, Günay Can, Mark Woodward, Esther Lopez-Garcia, Mauro Virgílio Gomes de Barros, Ahmed A. Madar, Shoaib Afzal, Melanie J. Cowan, Gareth Stratton, Eduardo Salazar Martinez, Sameer Narake, Norie Sawada, Deepak Amarapurkar, Deepa Weerasekera, Diana A. Santos, Marjeta Majer, Herman Schargrodsky, Bruna Gonçalves Cordeiro da Silva, Ebrahim Eftekhar, Jesús Vioque, Marisa K. Sophiea, Teresa Shamah-Levy, María Dolores Chirlaque, Mohd Azahadi Omar, Stefan Söderberg, Isabel O. Oliveira, Joanne Katz, Xingwang Ye, Christophe Tzourio, Marie Zins, Aneta Weres, Ulrich Keil, Haiquan Xu, Akihiro Yoshihara, Rachel Dankner, Gabriella Gruden, Maroje Sorić, Hanspeter Stamm, Kim Overvad, Yanping Li, Carsten Oliver Schmidt, Christa L. Lilly, Veikko Salomaa, Gilad Twig, Senthil K Vasan, Qian Wang, Liufu Cui, Andrzej Galbarczyk, Sylvain Sebert, Wilma M. Hopman, Karl-Heinz Jöckel, Ari Voutilainen, Peter Schnohr, Jerzy Chudek, Katia Vergetti Bloch, Vincenzo Capuano, Jyh Eiin Wong, Torben Jørgensen, Anja Schienkiewitz, Nader Saki, Carolina Tarqui-Mamani, Maria Cecília Formoso Assunção, Kazi M. Jamil, Juraci Almeida Cesar, Pedro J Ortiz, Delphine De Smedt, Luciana Zaccagni, Lynne M. Boddy, Jie Hao, David Alejandro González-Chica, Romana Roccaldo, Sara Magnacca, Peter Stehle, Victoria Farrugia Sant'Angelo, Gry Skodje, Maryam Keramati, Tabara Yasuharu, Ali Ghanbari, Gyulli M. Kazakbaeva, Takuro Furusawa, Felicia Cañete, Kari Kuulasmaa, Justina Vaitkeviciute, (NCD-RisC), NCD Risk Factor Collaboration, Imperial College London, Harvard T.H. Chan School of Public Health, Middlesex University [London], Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Montpellier Interdisciplinary center on Sustainable Agri-food systems (Social and nutritional sciences) (UMR MoISA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire (IGE-PCV), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Wellcome TrustEuropean Commission, Clinical Developmental Psychology, APH - Mental Health, Sociology, The Social Context of Aging (SoCA), Nutrition and Health, Iurilli, Maria LC [0000-0003-0409-1635], Zhou, Bin [0000-0002-1741-8628], Ezzati, Majid [0000-0002-2109-8081], Apollo - University of Cambridge Repository, Epidemiology and Data Science, APH - Aging & Later Life, APH - Societal Participation & Health, Public and occupational health, APH - Health Behaviors & Chronic Diseases, VU University medical center, APH - Personalized Medicine, AGEM - Endocrinology, metabolism and nutrition, ACS - Diabetes & metabolism, APH - Global Health, ARD - Amsterdam Reproduction and Development, Adult Psychiatry, Global Health, APH - Quality of Care, APH - Methodology, ACS - Atherosclerosis & ischemic syndromes, Gómez Santos, Santiago Felipe, NCD Risk Factor Collaboration (NCD-RisC), Faculdade de Desporto, Faculdade de Ciências da Nutrição e Alimentação, Faculdade de Medicina, Tampere University, Clinical Medicine, Department of Clinical Chemistry, Eye Centre, Harvard TH Chan School of Public Health, Middlesex University, World Health Organization, Ministry of Health, University of Lausanne, Eduardo Mondlane University, Victor Babes University of Medicine and Pharmacy Timisoara, University of Sydney, Health and Nutrition, University of Auckland, Seoul National University, ICMR - National Institute of Nutrition, Capital Medical University Beijing An Zhen Hospital, Universidad Peruana Cayetano Heredia, University Tunis El Manar, University of Oulu, University of Zagreb, University of Ljubljana, Caja Costarricense de Seguro Social, Al-Quds University, National Center of Public Healthcare, Qatar University, Birzeit University, Usmanu Danfodiyo University Teaching Hospital, Instituto Mexicano del Seguro Social, Flinders University, Mahidol University, BRAC James P Grant School of Public Health, University of Copenhagen, Copenhagen University Hospital, Food and Nutrition Research Institute, Urmia University of Medical Sciences, Instituto Nacional de Ciencias Médicas y Nutrición, University of Amsterdam, Shahrekord University of Medical Sciences, Non-Communicable Diseases Research Center, University of Oslo, University of Bremen, Republican Center for Health Promotion, Endocrinology and Genetics, Princess Nourah bint Abdulrahman University, Kuwait Institute for Scientific Research, King Abdulaziz University, Dasman Diabetes Institute, Aldara Hospital and Medical Center, King Abdullah International Medical Research Center, Luxembourg Institute of Health, Bispebjerg and Frederiksberg Hospital, Barcelona Institute for Global Health CIBERESP, World Health Organization Regional Office for the Eastern Mediterranean, Bombay Hospital and Medical Research Centre, Research Center for Social Determinants of Health, UMR CNRS-MNHN 7206 Eco-anthropologie, University of Lille, Lille University Hospital, Western Norway University of Applied Sciences, Norwegian School of Sport Sciences, Madras Diabetes Research Foundation, Zahedan University of Medical Sciences, National Institute of Public Health, Institute of Public Health of the University of Porto, Norwegian Institute of Public Health, University of Massachusetts Amherst, Abt Associates, University of Iceland, University of Yaoundé1, Federal University of Pelotas, University of Medicine 1, Oulu University Hospital, Banska Bystrica Regional Authority of Public Health, Tel- Aviv University, Hebrew University of Jerusalem, University of Porto Medical School, Neyshabur University of Medical Sciences, Research Institute for Endocrine Sciences, Non- Communicable Diseases Research Center, Indian Council of Medical Research, University of Science and Technology, Medical University of Lodz, Medical University of Gdansk, Universidad Autónoma de Madrid CIBERESP, University of Rzeszów, University of Palermo, Pan American Health Organization, Mohammed V University de Rabat, University of Pernambuco, Baqai Institute of Diabetology and Endocrinology, Universidade Federal de Santa Catarina (UFSC), Dalhousie University, Jordan University of Science and Technology, Federal University of Maranhao, Al-Farabi Kazakh National University, University College Dublin, Christian Medical College, Care and Consumer Protection, Cafam University Foundation, Kazakh National Medical University, Lithuanian University of Health Sciences, University of Saõ Paulo, B J Medical College, Chirayu Medical College, Sunder Lal Jain Hospital, The Hospital for Sick Children, Aga Khan University, Shandong University of Traditional Chinese Medicine, Jiao-Tong University School of Medicine, Universidad de la República, Institute of Medical Research and Medicinal Plant Studies, Ufa Eye Research Institute, Nepal Health Research Council, University of Montenegro, University of Southern Denmark, University of Gothenburg, Universidade Federal do Rio de Janeiro (UFRJ), National Institute for Public Health and the Environment, University of Turin, University College London, Liverpool John Moores University, Nanyang Technological University Singapore, German Institute of Human Nutrition, Endocrinology Research Centre, Centro de Educación Médica e Investigaciones Clínicas, IRCCS Neuromed, Toulouse University School of Medicine, University of Zurich, University Hospital KU Leuven, Flemish Agency for Care and Health, Ghent University, FrieslandCampina, Universidad Central de Venezuela, Bielefeld University, World Health Organization Regional Office for Europe, German Cancer Research Center, The Fred Hollows Foundation, University of Medicine and Pharmacy Bucharest, Swansea University, University College Copenhagen, Institute of Public Health, Munster Technological University, Universidad de La Laguna, University of Malta, Vanderbilt University, Canadian Fitness and Lifestyle Research Institute, Hospital Santa Maria, Istanbul University - Cerrahpasa, Universidade Federal de Juiz de Fora, Ministry of Public Health, Gaetano Fucito Hospital, University of Groningen, Karolinska Institutet, Centro de Estudios sobre Nutrición Infantil, University of Porto, University of Zaragoza, Santiago de Compostela University, Council for Agricultural Research and Economics, Federal University of Rio Grande, India Diabetes Research Foundation, Duke-NUS Medical School, ICMR - National Institute of Medical Statistics, Singapore Eye Research Institute, Academia Sinica, Capital Institute of Pediatrics, Duke University, Kailuan General Hospital, University of Oxford, Ahvaz Jundishapur University of Medical Sciences, The Gertner Institute for Epidemiology and Health Policy Research, National Centre of Public Health and Analyses, University of Fribourg, Ministry of Health and Welfare, CIBER Epidemiología y Salud Pública, Universidade Estadual Paulista (UNESP), Medical University of Silesia, Charles University, Thomayer Hospital, Primary Health Care, Carol Davila University of Medicine and Pharmacy, Katholieke Universiteit Leuven, Statistics Canada, UMR CNRS- MNHN 7206 Eco-anthropologie, Agency for Preventive and Social Medicine, University of Southampton, Institut Pasteur de Lille, Malawi Epidemiology and Intervention Research Unit, CIBEROBN, University of Debrecen, University of Medicine and Pharmacy Carol Davila, Universidade Federal do Rio Grande do Sul, National Research Council, Eftimie Murgu University Resita, Spanish Agency for Food Safety and Nutrition, Indian Statistical Institute, Tabriz Health Services Management Research Center, Geneva University Hospitals, Sciensano, University Medical Centers, National Research Centre for Preventive Medicine, Innovating Health International, University of Montreal, French National Research Institute for Sustainable Development, French Public Health Agency, Mediterranea Cardiocentro, Universidade do Vale do Rio dos Sinos, Epidemiology and Microbiology, National Council of Scientific and Technical Research, Ministry of Health and Medical Education, University of Novi Sad, National Institute of Nutrition, University of Queensland, Istituto Superiore di Sanita`, Universidad de Cuenca, Helmholtz Zentrum München, Tehran University of Medical Sciences, Ministere de la Santéet de l’Hygiene Publique, University Hospital Düsseldorf, National Institute of Cardiology, Medical University of Lod, Beijing Center for Disease Prevention and Control, UMI 3189 ESS, Beth Israel Deaconess Medical Center, Harvard Medical School, Scuola Superiore Sant’Anna, University of Latvia, Ministry of Health and Medical Services, Hormozgan University of Medical Sciences, University of Benin, University of Skövde, National Institute of Nutrition and Food Technology, The University of the West Indies, University of California Davis, University of Stellenbosch, University of Duisburg- Essen, Karadeniz Technical University, University of Helsinki, Mashhad University of Medical Sciences, Rafsanjan University of Medical Sciences, Queen’s University of Belfast, Tabriz University of Medical Sciences, Fasa University of Medical Sciences, Shiraz University of Medical Sciences, Baqai Medical University, Centro de Salud Villanueva Norte, Hospital Don Benito-Villanueva de la Serena, University of Insubria, Pontificia Universidad Católica de Chile, Institute of Mother and Child, Swiss Tropical and Public Health Institute, University of Basel, University of Tartu, Universiti Sains Malaysia, Umeå University, Federal University of Saõ Paulo, Hospital Universitario Son Espases, Hospital de Clinicas de Porto Alegre, Universitas Sumatera Utara, Kindai University, Kyoto University, Medical University of Warsaw, Jagiellonian University Medical College, Ministero della Salute DG Prevenzione Sanitaria, University of Catania, CIBER en Epidemiología y Salud Pública, Africa Health Research Institute, Geneva University Medical School, Universidade Federal de Minas Gerais (UFMG), Utrecht University, Wageningen University, University of Adelaide, Lund University, Aristotle University of Thessaloniki, Institut National de la Santéet de la Recherche Médicale, Paris University, McGill University, Gasol Foundation, University of Lleida, PASs Hirszfeld Institute of Immunology and Experimental Therapy, Universidad Politécnica de Madrid, St Anne’s University Hospital, Centro de Estudios en Diabetes A.C, Universidad Autónoma de Santo Domingo, Institute for Clinical and Experimental Medicine, Children’s Memorial Health Institute, National Center of Cardiovascular Diseases, University of Ferrara, Authority 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Federal de Pernambuco (UFPE), Universidad Autónoma de Bucaramanga, ETH Zurich, Chronic Diseases Research Center, University of Hong Kong, The Chinese University of Hong Kong, University of Western Australia, University Ramon Llull, Kingston Health Sciences Centre, Fundación Oftalmológica de Santander, University Oran 1, Ministry of Health and Sports, Peking University, VU University Medical Center, American University of Beirut, Cairo University, Erasmus Medical Center Rotterdam, Medical University Varna, The University of Tokyo, Deakin University, Tokyo Metropolitan Institute of Gerontology, Hadassah University Medical Center, Norwegian University of Science and Technology, University of Melbourne, Sports University of Tirana, University Hospital Center Zagreb, University of Zagreb School of Medicine, Heart Foundation, Guangzhou 12th Hospital, Universidad Eugenio Maria de Hostos, University of Duisburg-Essen, Simon Fraser University, Institute of Molecular and Clinical Ophthalmology Basel, University of New South Wales, World Health Organization Country Office, Guilan University of Medical Sciences, University of Opole, Finnish Institute for Health and Welfare, Gulu University, University of Crete, Sri Venkateswara University, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Hellenic Medical Association for Obesity, National and Kapodistrian University of Athens, Maharajgunj Medical Campus, Aarhus University, Johns Hopkins Bloomberg School of Public Health, Pennington Biomedical Research Center, National Institute of Epidemiology, University of Münster, Israel Center for Disease Control, Research Institute for Primordial Prevention of Non- communicable Disease, Amsterdam UMC Public Health Research Institute, South African Medical Research Council, Kyrgyz State Medical Academy, Research Institute of Child Nutrition, Shahid Beheshti University of Medical Sciences, University of Cambridge, Mazandaran University of Medical Sciences, Hypertension Research Center, Medical University of Innsbruck, VASCage, Muhimbili University of Health and Allied Sciences, Yonsei University College of Medicine, National Cancer Center, Sahlgrenska University Hospital, University College South Denmark, Statistics Austria, B P Koirala Institute of Health Sciences, University of Vienna, Oulu Deaconess Institute Foundation, Tartu University Clinics, Kansai Medical University, Hungarian School Sport Federation, Ministry of Health and Quality of Life, University Hospital Ulm, North-West University, University of Jyväskylä, Amrita Institute of Medical Sciences, Institute of Endocrinology, All India Institute of Medical Sciences, African Population and Health Research Center, Hanoi University of Public Health, Hassan First University of Settat, Harokopio University, Sahlgrenska Academy, Endocrinology and Metabolism Research Center, University of Public Health, International Food Policy Research Institute, National University of Singapore, Hong Kong Polytechnic University, Tampere University Hospital, University of Douala, University of Cape Town, National Institute for Health Development, West Virginia University, Oswaldo Cruz Foundation Rene Rachou Research Institute, National Taiwan University, University of Chinese Academy of Sciences, Uppsala University, Taipei Medical University, Sports Medical Center of Minho, Universidad San Martín de Porres, Consejería de Sanidad Junta de Castilla y León, Universidade Federal de Ciências da Saúde de Porto Alegre, Norrbotten County Council, Ilembula Lutheran Hospital, Universidade Federal de Ouro Preto, University of Coimbra, Coimbra University Hospital Center, Institute of Neuroscience of the National Research Council, Baker Heart and Diabetes Institute, Agricultural University of Athens, Hospital Israelita Albert Einstein, SB RAS Federal Research Center Institute of Cytology and Genetics, University of Otago, University of Padua, Hellenic Mediterranean University, Loughborough University, Lausanne University Hospital, Escola Nacional de Saúde Pública Sergio Arouca, CIBERCV, Institut Hospital del Mar d’Investigacions Mediques, Mary Immaculate College, Emory University, Hungarian Society of Sports Medicine, Paracelsus Medical University, Universidade Estadual do Centro-Oeste, Sher-i-Kashmir Institute of Medical Sciences, UiT The Arctic University of Norway, ICMR - National Centre for Disease Informatics and Research, Cape Peninsula University of Technology, Brown University, London School of Hygiene & Tropical Medicine, University of Edinburgh, Shahid Sadoughi University of Medical Sciences, Robert Koch Institute, Universidade de Lisboa, Women’s Social and Health Studies Foundation, Democritus University, Grigore T Popa University of Medicine and Pharmacy, Universita` degli Studi di Firenze, Ain Shams University, Isfahan Cardiovascular Research Center, University of Strasbourg, Strasbourg University Hospital, Mulago Hospital, University of San Carlos of Guatemala, University of Limpopo, University of Medical Sciences of Cienfuegos, Royal College of Surgeons in Ireland, La Trobe University, International Institute of Molecular and Cell Biology, Instituto Conmemorativo Gorgas de Estudios de la Salud, University of Brescia, Ministry of Health and Social Protection, University of Limerick, Croatian Institute of Public Health, Universiti Kebangsaan Malaysia, Bushehr University of Medical Sciences, Ulm University, Kobe University, Suraj Eye Institute, UNICEF, University Medicine Greifswald, National Institute of Hygiene and Epidemiology, University of Medicine and Pharmacy at Ho Chi Minh City, Hanoi Medical University, LifeDoc Health, Heartfile, Eastern Mediterranean Public Health Network, University of Manchester, State University of Medicine and Pharmacy, Tachikawa General Hospital, Korea Centers for Disease Control and Prevention, Japan Wildlife Research Center, Istanbul University, Universidade Federal do Paraná (UFPR), University of Madeira, University of Puerto Rico, Center for Clinical Research and Prevention, MRC Lifecourse Epidemiology Unit, Kwame Nkrumah University of Science and Technology, UniSanté, Prevention and Clinical Network, University of Wisconsin-Madison, Ruprecht-Karls-University of Heidelberg, IRCCS Ente Ospedaliero Specializzato in Gastroenterologia S. de Bellis, Zayed University, Catholic University of Daegu, Science and Technology of Târgu Mures, Jivandeep Hospital, Healis- Sekhsaria Institute for Public Health, National Dental Care Centre Singapore, Universidad de Málaga, University Hospital of Varese, Vietnam National Heart Institute, Clínica de Medicina Avanzada Dr. Abel González, Leibniz Institute for Prevention Research and Epidemiology - BIPS, University of Sarajevo, Cardiovascular Prevention Centre Udine, Pisa University Hospital, Public Health Agency of Catalonia, Ardabil University of Medical Sciences, Centre for Disease Prevention and Control, Alborz University of Medical Sciences, Pure Earth, Institute of Epidemiology Disease Control and Research, University of Turku, Institut Universitari d’Investigacióen AtencióPrima` ria Jordi Gol, Universiti Putra Malaysia, University of Malaya, Sotiria Hospital, University of Valencia, University of the Philippines, Slovak Academy of Sciences, Nutrition Research Foundation, Minas Gerais State Secretariat for Health, CS S. Agustín Ibsalut, Amsterdam Institute for Global Health and Development, National Institute of Health Doutor Ricardo Jorge, Universidade Nove de Julho, Public Health Agency of Canada, Canarian Health Service, Universidad Industrial de Santander, Associazione Calabrese di Epatologia, University of Minho, Fiji National University, Spanish Nutrition Foundation, Public Health Agency of Sweden, Institute of Food Sciences of the National Research Council, Sitaram Bhartia Institute of Science and Research, Kindergarten of Avlonari, National Institute of Health, Catalan Department of Health, Biodonostia Health Research Institute, Instituto de Saúde Ambiental, South Karelia Social and Health Care District, McMaster University, University of Saõ Paulo Clinics Hospital, Hospital Italiano de Buenos Aires, Rigshospitalet, Academic Medical Center of University of Amsterdam, The George Institute for Global Health, Center for Oral Health Services and Research Mid-Norway, Lagos State University College of Medicine, University of Las Palmas de Gran Canaria, Comenius University, National Center for Disease Control and Public Health, Nippon Medical School, Sungkyunkwan University, Finnish Institute of Occupational Health, Public Health Promotion and Development Organization, St Vincent’s Hospital, Nes Municipality, Health Polytechnic Jakarta II Institute, Diponegoro University, University of Bari, Institut Régional de SantéPublique, University of Bordeaux, Oslo Metropolitan University, Ss. Cyril and Methodius University, University of Leuven, Lamprecht und Stamm Sozialforschung und Beratung AG, Bonn University, National Institute of Public Health - National Institute of Hygiene, Kalina Malina Kindergarten, The Jikei University School of Medicine, Fu Jen Catholic University, National Statistical Office, Scientific Research Institute of Maternal and Child Health, University of Lincoln, Central University of Kerala, Amsterdam Public Health Research Institute, Health Service of Murcia, Institut d’Investigacio Sanitaria Illes Balears, University of Bologna, Hellenic Health Foundation, Government Medical College, Sefako Makgatho Health Science University, Addis Ababa University, Universidad Centro-Occidental Lisandro Alvarado, Meharry Medical College, Dokuz Eylul University, University of Tampere Tays Eye Center, Sabiha Gokcen Ilkokulu, Polytechnic Institute of Porto, Icahn School of Medicine at Mount Sinai, Universidad CEU San Pablo, University Miguel Hernandez, Vrije Universiteit Amsterdam, Sunflower Nursery School, North Karelia Center for Public Health, University of the Witwatersrand, Medical University of Vienna, Cork Institute of Technology, Institute for Medical Research, Xinjiang Medical University, Shanghai Educational Development Co. Ltd, Orebro University, University of London, Universitas Indonesia, Institute of Food and Nutrition Development of Ministry of Agriculture and Rural Affairs, Children’s Hospital of Fudan University, University of Cyprus, Niigata University, International Medical University, Iran University of Medical Sciences, Center for Diabetes and Endocrine Care, Peking University First Hospital, Jiangsu Provincial Center for Disease Control and Prevention, Sun Yat-sen University, West Kazakhstan Medical University, Inner Mongolia Medical University, University of Ghana, Maria Lc Iurilli , Bin Zhou , James E Bennett , Rodrigo M Carrillo-Larco , Marisa K Sophiea , Andrea Rodriguez-Martinez , Honor Bixby , Bethlehem D Solomon , Cristina Taddei , Goodarz Danaei , Mariachiara Di Cesare , Gretchen A Stevens , Leanne M Riley , Stefan Savin , Melanie J Cowan , Pascal Bovet , Albertino Damasceno , Adela Chirita-Emandi , Alison J Hayes , Nayu Ikeda , Rod T Jackson , Young-Ho Khang , Avula Laxmaiah , Jing Liu , J Jaime Miranda , Olfa Saidi , Sylvain Sebert , Maroje Sorić , Gregor Starc , Edward W Gregg , Leandra Abarca-Gómez , Ziad A Abdeen , Shynar Abdrakhmanova , Suhaila Abdul Ghaffar , Hanan F Abdul Rahim , Niveen M Abu-Rmeileh , Jamila Abubakar Garba , Benjamin Acosta-Cazares , Robert J Adams , Wichai Aekplakorn , Kaosar Afsana , Shoaib Afzal , Imelda A Agdeppa , Javad Aghazadeh-Attari , Carlos A Aguilar-Salinas , Charles Agyemang , Mohamad Hasnan Ahmad , Noor Ani Ahmad , Ali Ahmadi , Naser Ahmadi , Soheir H Ahmed , Wolfgang Ahrens , Gulmira Aitmurzaeva , Kamel Ajlouni , Hazzaa M Al-Hazzaa , Badreya Al-Lahou , Rajaa Al-Raddadi , Monira Alarouj , Fadia AlBuhairan , Shahla AlDhukair , Mohamed M Ali , Abdullah Alkandari , Ala'a Alkerwi , Kristine Allin , Mar Alvarez-Pedrerol , Eman Aly , Deepak N Amarapurkar , Parisa Amiri , Norbert Amougou , Philippe Amouyel , Lars Bo Andersen , Sigmund A Anderssen , Lars Ängquist , Ranjit Mohan Anjana , Alireza Ansari-Moghaddam , Hajer Aounallah-Skhiri , Joana Araújo , Inger Ariansen , Tahir Aris , Raphael E Arku , Nimmathota Arlappa , Krishna K Aryal , Thor Aspelund , Felix K Assah , Maria Cecília F Assunção , May Soe Aung , Juha Auvinen , Mária Avdicová , Shina Avi , Ana Azevedo , Mohsen Azimi-Nezhad , Fereidoun Azizi , Mehrdad Azmin , Bontha V Babu , Maja Bæksgaard Jørgensen , Azli Baharudin , Suhad Bahijri , Jennifer L Baker , Nagalla Balakrishna , Mohamed Bamoshmoosh , Maciej Banach , Piotr Bandosz , José R Banegas , Joanna Baran , Barbagallo CM, Alberto Barceló , Amina Barkat , Aluisio Jd Barros , Mauro Virgílio Gomes Barros , Abdul Basit , Joao Luiz D Bastos , Iqbal Bata , Anwar M Batieha , Rosangela L Batista , Zhamilya Battakova , Assembekov Batyrbek , Louise A Baur , Robert Beaglehole , Silvia Bel-Serrat , Antonisamy Belavendra , Habiba Ben Romdhane , Judith Benedics , Mikhail Benet , Ingunn Holden Bergh , Salim Berkinbayev , Antonio Bernabe-Ortiz , Gailute Bernotiene , Heloísa Bettiol , Jorge Bezerra , Aroor Bhagyalaxmi , Sumit Bharadwaj , Santosh K Bhargava , Zulfiqar A Bhutta , Hongsheng Bi , Yufang Bi , Daniel Bia , Elysée Claude Bika Lele, Mukharram M Bikbov , Bihungum Bista , Dusko J Bjelica , Peter Bjerregaard , Espen Bjertness , Marius B Bjertness , Cecilia Björkelund , Katia V Bloch , Anneke Blokstra , Simona Bo , Martin Bobak , Lynne M Boddy , Bernhard O Boehm , Heiner Boeing , Jose G Boggia , Elena Bogova , Carlos P Boissonnet , Stig E Bojesen , Marialaura Bonaccio , Vanina Bongard , Alice Bonilla-Vargas , Matthias Bopp , Herman Borghs , Lien Braeckevelt , Lutgart Braeckman , Marjolijn Ce Bragt , Imperia Brajkovich , Francesco Branca , Juergen Breckenkamp , João Breda , Hermann Brenner , Lizzy M Brewster , Garry R Brian , Lacramioara Brinduse , Sinead Brophy , Graziella Bruno , H Bas Bueno-de-Mesquita , Anna Bugge , Marta Buoncristiano , Genc Burazeri , Con Burns , Antonio Cabrera de León , Joseph Cacciottolo , Hui Cai , Tilema Cama , Christine Cameron , José Camolas , Günay Can , Ana Paula C Cândido , Felicia Cañete , Mario V Capanzana , Nadežda Capková , Eduardo Capuano , Vincenzo Capuano , Marloes Cardol , Viviane C Cardoso , Axel C Carlsson , Esteban Carmuega , Joana Carvalho , José A Casajús , Felipe F Casanueva , Ertugrul Celikcan , Laura Censi , Marvin Cervantes-Loaiza , Juraci A Cesar , Snehalatha Chamukuttan , Angelique W Chan , Queenie Chan , Himanshu K Chaturvedi , Nish Chaturvedi , Norsyamlina Che Abdul Rahim , Miao Li Chee , Chien-Jen Chen , Fangfang Chen , Huashuai Chen , Shuohua Chen , Zhengming Chen , Ching-Yu Cheng , Bahman Cheraghian , Angela Chetrit , Ekaterina Chikova-Iscener , Arnaud Chiolero , Shu-Ti Chiou , María-Dolores Chirlaque , Belong Cho , Kaare Christensen , Diego G Christofaro , Jerzy Chudek , Renata Cifkova , Michelle Cilia , Eliza Cinteza , Frank Claessens , Janine Clarke , Els Clays , Emmanuel Cohen , Hans Concin , Susana C Confortin , Cyrus Cooper , Tara C Coppinger , Eva Corpeleijn , Simona Costanzo , Dominique Cottel , Chris Cowell , Cora L Craig , Amelia C Crampin , Ana B Crujeiras , Semánová Csilla , Alexandra M Cucu , Liufu Cui , Felipe V Cureau , Ewelina Czenczek-Lewandowska , Graziella D'Arrigo , Eleonora d'Orsi , Liliana Dacica , María Ángeles Dal Re Saavedra , Jean Dallongeville , Camilla T Damsgaard , Rachel Dankner , Thomas M Dantoft , Parasmani Dasgupta , Saeed Dastgiri , Luc Dauchet , Kairat Davletov , Guy De Backer , Dirk De Bacquer , Giovanni de Gaetano , Stefaan De Henauw , Paula Duarte de Oliveira , David De Ridder , Karin De Ridder , Susanne R de Rooij , Delphine De Smedt , Mohan Deepa , Alexander D Deev , Vincent Jr DeGennaro , Abbas Dehghan , Hélène Delisle , Francis Delpeuch , Stefaan Demarest , Elaine Dennison , Katarzyna Dereń , Valérie Deschamps , Meghnath Dhimal , Augusto F Di Castelnuovo , Juvenal Soares Dias-da-Costa , María Elena Díaz-Sánchez , Alejandro Diaz , Zivka Dika , Shirin Djalalinia , Visnja Djordjic , Ha Tp Do , Annette J Dobson , Maria Benedetta Donati , Chiara Donfrancesco , Silvana P Donoso , Angela Döring , Maria Dorobantu , Ahmad Reza Dorosty , Kouamelan Doua , Nico Dragano , Wojciech Drygas , Jia Li Duan , Charmaine A Duante , Priscilla Duboz , Rosemary B Duda , Vesselka Duleva , Virginija Dulskiene , Samuel C Dumith , Anar Dushpanova , Vilnis Dzerve , Elzbieta Dziankowska-Zaborszczyk , Ricky Eddie , Ebrahim Eftekhar , Eruke E Egbagbe , Robert Eggertsen , Sareh Eghtesad , Gabriele Eiben , Ulf Ekelund , Mohammad El-Khateeb , Jalila El Ati , Denise Eldemire-Shearer , Marie Eliasen , Paul Elliott , Reina Engle-Stone , Macia Enguerran , Rajiv T Erasmus , Raimund Erbel , Cihangir Erem , Louise Eriksen , Johan G Eriksson , Jorge Escobedo-de la Peña , Saeid Eslami , Ali Esmaeili , Alun Evans , David Faeh , Albina A Fakhretdinova , Caroline H Fall , Elnaz Faramarzi , Mojtaba Farjam , Victoria Farrugia Sant'Angelo , Farshad Farzadfar , Mohammad Reza Fattahi , Asher Fawwad , Francisco J Felix-Redondo , Trevor S Ferguson , Romulo A Fernandes , Daniel Fernández-Bergés , Daniel Ferrante , Thomas Ferrao , Marika Ferrari , Marco M Ferrario , Catterina Ferreccio , Eldridge Ferrer , Jean Ferrieres , Thamara Hubler Figueiró , Anna Fijalkowska , Günther Fink , Krista Fischer , Leng Huat Foo , Maria Forsner , Heba M Fouad , Damian K Francis , Maria do Carmo Franco , Ruth Frikke-Schmidt , Guillermo Frontera , Flavio D Fuchs , Sandra C Fuchs , Isti I Fujiati , Yuki Fujita , Matsuda Fumihiko , Takuro Furusawa , Zbigniew Gaciong , Mihai Gafencu , Andrzej Galbarczyk , Henrike Galenkamp , Daniela Galeone , Myriam Galfo , Fabio Galvano , Jingli Gao , Manoli Garcia-de-la-Hera , Marta García-Solano , Dickman Gareta , Sarah P Garnett , Jean-Michel Gaspoz , Magda Gasull , Adroaldo Cesar Araujo Gaya , Anelise Reis Gaya , Andrea Gazzinelli , Ulrike Gehring , Harald Geiger , Johanna M Geleijnse , Ali Ghanbari , Erfan Ghasemi , Oana-Florentina Gheorghe-Fronea , Simona Giampaoli , Francesco Gianfagna , Tiffany K Gill , Jonathan Giovannelli , Glen Gironella , Aleksander Giwercman , Konstantinos Gkiouras , Justyna Godos , Sibel Gogen , Marcel Goldberg , Rebecca A Goldsmith , David Goltzman , Santiago F Gómez , Aleksandra Gomula , Bruna Goncalves Cordeiro da Silva , Helen Gonçalves , David A Gonzalez-Chica , Marcela Gonzalez-Gross , Margot González-Leon , Juan P González-Rivas , Clicerio González-Villalpando , María-Elena González-Villalpando , Angel R Gonzalez , Frederic Gottrand , Antonio Pedro Graça , Sidsel Graff-Iversen , Dušan Grafnetter , Aneta Grajda , Maria G Grammatikopoulou , Ronald D Gregor , Tomasz Grodzicki , Else Karin Grøholt , Anders Grøntved , Giuseppe Grosso , Gabriella Gruden , Dongfeng Gu , Emanuela Gualdi-Russo , Pilar Guallar-Castillón , Andrea Gualtieri , Elias F Gudmundsson , Vilmundur Gudnason , Ramiro Guerrero , Idris Guessous , Andre L Guimaraes , Martin C Gulliford , Johanna Gunnlaugsdottir , Marc J Gunter , Xiu-Hua Guo , Yin Guo , Prakash C Gupta , Rajeev Gupta , Oye Gureje , Beata Gurzkowska , Enrique Gutiérrez-González , Laura Gutierrez , Felix Gutzwiller , Seongjun Ha , Farzad Hadaegh , Charalambos A Hadjigeorgiou , Rosa Haghshenas , Hamid Hakimi , Jytte Halkjær , Ian R Hambleton , Behrooz Hamzeh , Dominique Hange , Abu Am Hanif , Sari Hantunen , Jie Hao , Rachakulla Hari Kumar , Seyed Mohammad Hashemi-Shahri , Maria Hassapidou , Jun Hata , Teresa Haugsgjerd , Jiang He , Yuan He , Yuna He , Regina Heidinger-Felso , Mirjam Heinen , Tatjana Hejgaard , Marleen Elisabeth Hendriks , Rafael Dos Santos Henrique , Ana Henriques , Leticia Hernandez Cadena , Sauli Herrala , Victor M Herrera , Isabelle Herter-Aeberli , Ramin Heshmat , Allan G Hill , Sai Yin Ho , Suzanne C Ho , Michael Hobbs , Michelle Holdsworth , Reza Homayounfar , Clara Homs , Wilma M Hopman , Andrea Rvr Horimoto , Claudia M Hormiga , Bernardo L Horta , Leila Houti , Christina Howitt , Thein Thein Htay , Aung Soe Htet , Maung Maung Than Htike , Yonghua Hu , José María Huerta , Ilpo Tapani Huhtaniemi , Laetitia Huiart , Constanta Huidumac Petrescu , Martijn Huisman , Abdullatif Husseini , Chinh Nguyen Huu , Inge Huybrechts , Nahla Hwalla , Jolanda Hyska , Licia Iacoviello , Jesús M Ibarluzea , Mohsen M Ibrahim , Norazizah Ibrahim Wong , M Arfan Ikram , Violeta Iotova , Vilma E Irazola , Takafumi Ishida , Muhammad Islam , Sheikh Mohammed Shariful Islam , Masanori Iwasaki , Jeremy M Jacobs , Hashem Y Jaddou , Tazeen Jafar , Kenneth James , Kazi M Jamil , Konrad Jamrozik , Imre Janszky , Edward Janus , Juel Jarani , Marjo-Riitta Jarvelin , Grazyna Jasienska , Ana Jelakovic , Bojan Jelakovic , Garry Jennings , Anjani Kumar Jha , Chao Qiang Jiang , Ramon O Jimenez , Karl-Heinz Jöckel , Michel Joffres , Mattias Johansson , Jari J Jokelainen , Jost B Jonas , Jitendra Jonnagaddala , Torben Jørgensen , Pradeep Joshi , Farahnaz Joukar , Dragana P Jovic , Jacek J Jóźwiak , Anne Juolevi , Gregor Jurak , Iulia Jurca Simina , Vesna Juresa , Rudolf Kaaks , Felix O Kaducu , Anthony Kafatos , Eero O Kajantie , Zhanna Kalmatayeva , Ofra Kalter-Leibovici , Yves Kameli , Freja B Kampmann , Kodanda R Kanala , Srinivasan Kannan , Efthymios Kapantais , Argyro Karakosta , Line L Kårhus , Khem B Karki , Marzieh Katibeh , Joanne Katz , Peter T Katzmarzyk , Jussi Kauhanen , Prabhdeep Kaur , Maryam Kavousi , Gyulli M Kazakbaeva , Ulrich Keil , Lital Keinan Boker , Sirkka Keinänen-Kiukaanniemi , Roya Kelishadi , Cecily Kelleher , Han Cg Kemper , Andre P Kengne , Maryam Keramati , Alina Kerimkulova , Mathilde Kersting , Timothy Key , Yousef Saleh Khader , Davood Khalili , Kay-Tee Khaw , Bahareh Kheiri , Motahareh Kheradmand , Alireza Khosravi , Ilse Msl Khouw , Ursula Kiechl-Kohlendorfer , Stefan Kiechl , Japhet Killewo , Dong Wook Kim , Hyeon Chang Kim , Jeongseon Kim , Jenny M Kindblom , Heidi Klakk , Magdalena Klimek , Jeannette Klimont , Jurate Klumbiene , Michael Knoflach , Bhawesh Koirala , Elin Kolle , Patrick Kolsteren , Jürgen König , Raija Korpelainen , Paul Korrovits , Magdalena Korzycka , Jelena Kos , Seppo Koskinen , Katsuyasu Kouda , Viktoria A Kovacs , Sudhir Kowlessur , Slawomir Koziel , Jana Kratenova , Wolfgang Kratzer , Susi Kriemler , Peter Lund Kristensen , Steinar Krokstad , Daan Kromhout , Herculina S Kruger , Ruzena Kubinova , Renata Kuciene , Urho M Kujala , Enisa Kujundzic , Zbigniew Kulaga , R Krishna Kumar , Marie Kunešová , Pawel Kurjata , Yadlapalli S Kusuma , Kari Kuulasmaa , Catherine Kyobutungi , Quang Ngoc La , Fatima Zahra Laamiri , Tiina Laatikainen , Carl Lachat , Youcef Laid , Tai Hing Lam , Christina-Paulina Lambrinou , Edwige Landais , Vera Lanska , Georg Lappas , Bagher Larijani , Tint Swe Latt , Laura Lauria , Maria Lazo-Porras , Gwenaëlle Le Coroller , Khanh Le Nguyen Bao , Agnès Le Port , Tuyen D Le , Jeannette Lee , Jeonghee Lee , Paul H Lee , Nils Lehmann , Terho Lehtimäki , Daniel Lemogoum , Naomi S Levitt , Yanping Li , Merike Liivak , Christa L Lilly , Wei-Yen Lim , M Fernanda Lima-Costa , Hsien-Ho Lin , Xu Lin , Yi-Ting Lin , Lars Lind , Allan Linneberg , Lauren Lissner , Mieczyslaw Litwin , Lijuan Liu , Wei-Cheng Lo , Helle-Mai Loit , Khuong Quynh Long , Luis Lopes , Oscar Lopes , Esther Lopez-Garcia , Tania Lopez , Paulo A Lotufo , José Eugenio Lozano , Janice L Lukrafka , Dalia Luksiene , Annamari Lundqvist , Robert Lundqvist , Nuno Lunet , Charles Lunogelo , Michala Lustigová , Edyta Łuszczki , Guansheng Ma , Jun Ma , Xu Ma , George Ll Machado-Coelho , Aristides M Machado-Rodrigues , Luisa M Macieira , Ahmed A Madar , Stefania Maggi , Dianna J Magliano , Sara Magnacca , Emmanuella Magriplis , Gowri Mahasampath , Bernard Maire , Marjeta Majer , Marcia Makdisse , Päivi Mäki , Fatemeh Malekzadeh , Reza Malekzadeh , Rahul Malhotra , Kodavanti Mallikharjuna Rao , Sofia K Malyutina , Lynell V Maniego , Yannis Manios , Jim I Mann , Fariborz Mansour-Ghanaei , Enzo Manzato , Paula Margozzini , Anastasia Markaki , Oonagh Markey , Eliza Markidou Ioannidou , Pedro Marques-Vidal , Larissa Pruner Marques , Jaume Marrugat , Yves Martin-Prevel , Rosemarie Martin , Reynaldo Martorell , Eva Martos , Katharina Maruszczak , Stefano Marventano , Luis P Mascarenhas , Shariq R Masoodi , Ellisiv B Mathiesen , Prashant Mathur , Alicia Matijasevich , Tandi E Matsha , Christina Mavrogianni , Artur Mazur , Jean Claude N Mbanya , Shelly R McFarlane , Stephen T McGarvey , Martin McKee , Stela McLachlan , Rachael M McLean , Scott B McLean , Breige A McNulty , Sounnia Mediene Benchekor , Jurate Medzioniene , Parinaz Mehdipour , Kirsten Mehlig , Amir Houshang Mehrparvar , Aline Meirhaeghe , Jørgen Meisfjord , Christa Meisinger , Ana Maria B Menezes , Geetha R Menon , Gert Bm Mensink , Maria Teresa Menzano , Alibek Mereke , Indrapal I Meshram , Andres Metspalu , Haakon E Meyer , Jie Mi , Kim F Michaelsen , Nathalie Michels , Kairit Mikkel , Karolina Milkowska , Jody C Miller , Cláudia S Minderico , G K Mini , Juan Francisco Miquel , Mohammad Reza Mirjalili , Daphne Mirkopoulou , Erkin Mirrakhimov , Marjeta Mišigoj-Durakovic , Antonio Mistretta , Veronica Mocanu , Pietro A Modesti , Sahar Saeedi Moghaddam , Bahram Mohajer , Mostafa K Mohamed , Shukri F Mohamed , Kazem Mohammad , Zahra Mohammadi , Noushin Mohammadifard , Reza Mohammadpourhodki , Viswanathan Mohan , Salim Mohanna , Muhammad Fadhli Mohd Yusoff , Iraj Mohebbi , Farnam Mohebi , Marie Moitry , Drude Molbo , Line T Møllehave , Niels C Møller , Dénes Molnár , Amirabbas Momenan , Charles K Mondo , Michele Monroy-Valle , Eric Monterrubio-Flores , Kotsedi Daniel K Monyeki , Jin Soo Moon , Mahmood Moosazadeh , Leila B Moreira , Alain Morejon , Luis A Moreno , Karen Morgan , Suzanne N Morin , Erik Lykke Mortensen , George Moschonis , Malgorzata Mossakowska , Aya Mostafa , Anabela Mota-Pinto , Jorge Mota , Mohammad Esmaeel Motlagh , Jorge Motta , Marcos André Moura-Dos-Santos , Malay K Mridha , Kelias P Msyamboza , Thet Thet Mu , Magdalena Muc , Boban Mugoša , Maria L Muiesan , Parvina Mukhtorova , Martina Müller-Nurasyid , Neil Murphy , Jaakko Mursu , Elaine M Murtagh , Kamarul Imran Musa , Sanja Music Milanovic , Vera Musil , Norlaila Mustafa , Iraj Nabipour , Shohreh Naderimagham , Gabriele Nagel , Balkish M Naidu , Farid Najafi , Harunobu Nakamura , Jana Námešná , Ei Ei K Nang , Vinay B Nangia , Martin Nankap , Sameer Narake , Paola Nardone , Matthias Nauck , William A Neal , Azim Nejatizadeh , Chandini Nekkantti , Keiu Nelis , Liis Nelis , Ilona Nenko , Martin Neovius , Flavio Nervi , Chung T Nguyen , Nguyen D Nguyen , Quang Ngoc Nguyen , Ramfis E Nieto-Martínez , Yury P Nikitin , Guang Ning , Toshiharu Ninomiya , Sania Nishtar , Marianna Noale , Oscar A Noboa , Helena Nogueira , Teresa Norat , Maria Nordendahl , Børge G Nordestgaard , Davide Noto , Natalia Nowak-Szczepanska , Mohannad Al Nsour , Irfan Nuhoglu , Eha Nurk , Terence W O'Neill , Dermot O'Reilly , Galina Obreja , Caleb Ochimana , Angélica M Ochoa-Avilés , Eiji Oda , Kyungwon Oh , Kumiko Ohara , Claes Ohlsson , Ryutaro Ohtsuka , Örn Olafsson , Maria Teresa A Olinto , Isabel O Oliveira , Mohd Azahadi Omar , Altan Onat , Sok King Ong , Lariane M Ono , Pedro Ordunez , Rui Ornelas , Ana P Ortiz , Pedro J Ortiz , Merete Osler , Clive Osmond , Sergej M Ostojic , Afshin Ostovar , Johanna A Otero , Kim Overvad , Ellis Owusu-Dabo , Fred Michel Paccaud , Cristina Padez , Ioannis Pagkalos , Elena Pahomova , Karina Mary de Paiva , Andrzej Pajak , Domenico Palli , Alberto Palloni , Luigi Palmieri , Wen-Harn Pan , Songhomitra Panda-Jonas , Arvind Pandey , Francesco Panza , Dimitrios Papandreou , Soon-Woo Park , Suyeon Park , Winsome R Parnell , Mahboubeh Parsaeian , Ionela M Pascanu , Patrick Pasquet , Nikhil D Patel , Ivan Pecin , Mangesh S Pednekar , Nasheeta Peer , Gao Pei , Sergio Viana Peixoto , Markku Peltonen , Alexandre C Pereira , Marco A Peres , Napoleón Pérez-Farinós , Cynthia M Pérez , Valentina Peterkova , Annette Peters , Astrid Petersmann , Janina Petkeviciene , Ausra Petrauskiene , Emanuela Pettenuzzo , Niloofar Peykari , Son Thai Pham , Rafael N Pichardo , Daniela Pierannunzio , Iris Pigeot , Hynek Pikhart , Aida Pilav , Lorenza Pilotto , Francesco Pistelli , Freda Pitakaka , Aleksandra Piwonska , Andreia N Pizarro , Pedro Plans-Rubió , Bee Koon Poh , Hermann Pohlabeln , Raluca M Pop , Stevo R Popovic , Miquel Porta , Georg Posch , Anil Poudyal , Dimitrios Poulimeneas , Hamed Pouraram , Farhad Pourfarzi , Akram Pourshams , Hossein Poustchi , Rajendra Pradeepa , Alison J Price , Jacqueline F Price , Rui Providencia , Jardena J Puder , Iveta Pudule , Soile E Puhakka , Maria Puiu , Margus Punab , Radwan F Qasrawi , Mostafa Qorbani , Tran Quoc Bao , Ivana Radic , Ricardas Radisauskas , Salar Rahimikazerooni , Mahfuzar Rahman , Mahmudur Rahman , Olli Raitakari , Manu Raj , Ellina Rakhimova , Sherali Rakhmatulloev , Ivo Rakovac , Sudha Ramachandra Rao , Ambady Ramachandran , Jacqueline Ramke , Elisabete Ramos , Rafel Ramos , Lekhraj Rampal , Sanjay Rampal , Vayia Rarra , Ramon A Rascon-Pacheco , Mette Rasmussen , Cassiano Ricardo Rech , Josep Redon , Paul Ferdinand M Reganit , Valéria Regecová , Luis Revilla , Abbas Rezaianzadeh , Lourdes Ribas-Barba , Robespierre Ribeiro , Elio Riboli , Adrian Richter , Fernando Rigo , Natascia Rinaldo , Tobias F Rinke de Wit , Ana Rito , Raphael M Ritti-Dias , Juan A Rivera , Cynthia Robitaille , Romana Roccaldo , Daniela Rodrigues , Fernando Rodríguez-Artalejo , María Del Cristo Rodriguez-Perez , Laura A Rodríguez-Villamizar , Ulla Roggenbuck , Rosalba Rojas-Martinez , Nipa Rojroongwasinkul , Dora Romaguera , Elisabetta L Romeo , Rafaela V Rosario , Annika Rosengren , Ian Rouse , Joel Gr Roy , Adolfo Rubinstein , Frank J Rühli , Jean-Bernard Ruidavets , Blanca Sandra Ruiz-Betancourt , Maria Ruiz-Castell , Emma Ruiz Moreno , Iuliia A Rusakova , Kenisha Russell Jonsson , Paola Russo , Petra Rust , Marcin Rutkowski , Charumathi Sabanayagam , Elena Sacchini , Harshpal S Sachdev , Alireza Sadjadi , Ali Reza Safarpour , Saeid Safiri , Nader Saki , Benoit Salanave , Eduardo Salazar Martinez , Diego Salmerón , Veikko Salomaa , Jukka T Salonen , Massimo Salvetti , Margarita Samoutian , Jose Sánchez-Abanto , Sandjaja , Susana Sans , Loreto Santa Marina , Diana A Santos , Ina S Santos , Lèlita C Santos , Maria Paula Santos , Osvaldo Santos , Rute Santos , Sara Santos Sanz , Jouko L Saramies , Luis B Sardinha , Nizal Sarrafzadegan , Thirunavukkarasu Sathish , Kai-Uwe Saum , Savvas Savva , Mathilde Savy , Norie Sawada , Mariana Sbaraini , Marcia Scazufca , Beatriz D Schaan , Angelika Schaffrath Rosario , Herman Schargrodsky , Anja Schienkiewitz , Sabine Schipf , Carsten O Schmidt , Ida Maria Schmidt , Peter Schnohr , Ben Schöttker , Sara Schramm , Stine Schramm , Helmut Schröder , Constance Schultsz , Aletta E Schutte , Aye Aye Sein , Rusidah Selamat , Vedrana Sember , Abhijit Sen , Idowu O Senbanjo , Sadaf G Sepanlou , Victor Sequera , Luis Serra-Majem , Jennifer Servais , Ludmila Ševcíková , Svetlana A Shalnova , Teresa Shamah-Levy , Morteza Shamshirgaran , Coimbatore Subramaniam Shanthirani , Maryam Sharafkhah , Sanjib K Sharma , Jonathan E Shaw , Amaneh Shayanrad , Ali Akbar Shayesteh , Lela Shengelia , Zumin Shi , Kenji Shibuya , Hana Shimizu-Furusawa , Dong Wook Shin , Majid Shirani , Rahman Shiri , Namuna Shrestha , Khairil Si-Ramlee , Alfonso Siani , Rosalynn Siantar , Abla M Sibai , Antonio M Silva , Diego Augusto Santos Silva , Mary Simon , Judith Simons , Leon A Simons , Agneta Sjöberg , Michael Sjöström , Gry Skodje , Jolanta Slowikowska-Hilczer , Przemyslaw Slusarczyk , Liam Smeeth , Hung-Kwan So , Fernanda Cunha Soares , Grzegorz Sobek , Eugène Sobngwi , Morten Sodemann , Stefan Söderberg , Moesijanti Ye Soekatri , Agustinus Soemantri , Reecha Sofat , Vincenzo Solfrizzi , Mohammad Hossein Somi , Emily Sonestedt , Yi Song , Thorkild Ia Sørensen , Elin P Sørgjerd , Charles Sossa Jérome , Victoria E Soto-Rojas , Aïcha Soumaré , Slavica Sovic , Bente Sparboe-Nilsen , Karen Sparrenberger , Angela Spinelli , Igor Spiroski , Jan A Staessen , Hanspeter Stamm , Maria G Stathopoulou , Kaspar Staub , Bill Stavreski , Jostein Steene-Johannessen , Peter Stehle , Aryeh D Stein , George S Stergiou , Jochanan Stessman , Ranko Stevanovic , Jutta Stieber , Doris Stöckl , Tanja Stocks , Jakub Stokwiszewski , Ekaterina Stoyanova , Gareth Stratton , Karien Stronks , Maria Wany Strufaldi , Lela Sturua , Ramón Suárez-Medina , Machi Suka , Chien-An Sun , Johan Sundström , Yn-Tz Sung , Jordi Sunyer , Paibul Suriyawongpaisal , Boyd A Swinburn , Rody G Sy , Holly E Syddall , René Charles Sylva , Moyses Szklo , Lucjan Szponar , E Shyong Tai , Mari-Liis Tammesoo , Abdonas Tamosiunas , Eng Joo Tan , Xun Tang , Maya Tanrygulyyeva , Frank Tanser , Yong Tao , Mohammed Rasoul Tarawneh , Jakob Tarp , Carolina B Tarqui-Mamani , Radka Taxová Braunerová , Anne Taylor , Julie Taylor , Félicité Tchibindat , William R Tebar , Grethe S Tell , Tania Tello , Yih Chung Tham , K R Thankappan , Holger Theobald , Xenophon Theodoridis , Lutgarde Thijs , Nihal Thomas , Betina H Thuesen , Lubica Tichá , Erik J Timmermans , Anne Tjonneland , Hanna K Tolonen , Janne S Tolstrup , Murat Topbas , Roman Topór-Madry , Liv Elin Torheim , María José Tormo , Michael J Tornaritis , Maties Torrent , Laura Torres-Collado , Stefania Toselli , Giota Touloumi , Pierre Traissac , Thi Tuyet-Hanh Tran , Dimitrios Trichopoulos , Antonia Trichopoulou , Oanh Th Trinh , Atul Trivedi , Lechaba Tshepo , Maria Tsigga , Shoichiro Tsugane , Azaliia M Tuliakova , Marshall K Tulloch-Reid , Fikru Tullu , Tomi-Pekka Tuomainen , Jaakko Tuomilehto , Maria L Turley , Gilad Twig , Per Tynelius , Themistoklis Tzotzas , Christophe Tzourio , Peter Ueda , Eunice Ugel , Flora Am Ukoli , Hanno Ulmer , Belgin Unal , Zhamyila Usupova , Hannu Mt Uusitalo , Nalan Uysal , Justina Vaitkeviciute , Gonzalo Valdivia , Susana Vale , Damaskini Valvi , Rob M van Dam , Johan Van der Heyden , Yvonne T van der Schouw , Koen Van Herck , Hoang Van Minh , Natasja M 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Claude N, McFarlane, Shelly R, McGarvey, Stephen T, McKee, Martin, McLachlan, Stela, McLean, Rachael M, McLean, Scott B, McNulty, Breige A, Benchekor, Sounnia Mediene, Medzioniene, Jurate, Mehdipour, Parinaz, Mehlig, Kirsten, Mehrparvar, Amir Houshang, Meirhaeghe, Aline, Meisfjord, Jørgen, Meisinger, Christa, Menezes, Ana Maria B, Menon, Geetha R, Mensink, Gert BM, Menzano, Maria Teresa, Mereke, Alibek, Meshram, Indrapal I, Metspalu, Andre, Meyer, Haakon E, Mi, Jie, Michaelsen, Kim F, Michels, Nathalie, Mikkel, Kairit, Milkowska, Karolina, Miller, Jody C, Minderico, Cláudia S, Mini, GK, Miquel, Juan Francisco, Mirjalili, Mohammad Reza, Mirkopoulou, Daphne, Mirrakhimov, Erkin, Mišigoj-Durakovic, Marjeta, Mistretta, Antonio, Mocanu, Veronica, Modesti, Pietro A, Moghaddam, Sahar Saeedi, Mohajer, Bahram, Mohamed, Mostafa K, Mohamed, Shukri F, Mohammad, Kazem, Mohammadi, Zahra, Mohammadifard, Noushin, Mohammadpourhodki, Reza, Mohan, Viswanathan, Mohanna, Salim, Yusoff, Muhammad Fadhli Mohd, 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Poudyal, Anil, Poulimeneas, Dimitrio, Pouraram, Hamed, Pourfarzi, Farhad, Pourshams, Akram, Poustchi, Hossein, Pradeepa, Rajendra, Price, Alison J, Price, Jacqueline F, Providencia, Rui, Puder, Jardena J, Pudule, Iveta, Puhakka, Soile E, Puiu, Maria, Punab, Margu, Qasrawi, Radwan F, Qorbani, Mostafa, Bao, Tran Quoc, Radic, Ivana, Radisauskas, Ricarda, Rahimikazerooni, Salar, Rahman, Mahfuzar, Rahman, Mahmudur, Raitakari, Olli, Raj, Manu, Rakhimova, Ellina, Rakhmatulloev, Sherali, Rakovac, Ivo, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramke, Jacqueline, Ramos, Elisabete, Ramos, Rafel, Rampal, Lekhraj, Rampal, Sanjay, Rarra, Vayia, Rascon-Pacheco, Ramon A, Rasmussen, Mette, Rech, Cassiano Ricardo, Redon, Josep, Reganit, Paul Ferdinand M, Regecová, Valéria, Revilla, Lui, Rezaianzadeh, Abba, Ribas-Barba, Lourde, Ribeiro, Robespierre, Riboli, Elio, Richter, Adrian, Rigo, Fernando, Rinaldo, Natascia, de Wit, Tobias F Rinke, Rito, Ana, Ritti-Dias, Raphael M, Rivera, Juan A, Robitaille, Cynthia, Roccaldo, Romana, Rodrigues, Daniela, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A, Roggenbuck, Ulla, Rojas-Martinez, Rosalba, Rojroongwasinkul, Nipa, Romaguera, Dora, Romeo, Elisabetta L, Rosario, Rafaela V, Rosengren, Annika, Rouse, Ian, Roy, Joel GR, Rubinstein, Adolfo, Rühli, Frank J, Ruidavets, Jean-Bernard, Ruiz-Betancourt, Blanca Sandra, Ruiz-Castell, Maria, Moreno, Emma Ruiz, Rusakova, Iuliia A, Jonsson, Kenisha Russell, Russo, Paola, Rust, Petra, Rutkowski, Marcin, Sabanayagam, Charumathi, Sacchini, Elena, Sachdev, Harshpal S, Sadjadi, Alireza, Safarpour, Ali Reza, Safiri, Saeid, Saki, Nader, Salanave, Benoit, Martinez, Eduardo Salazar, Salmerón, Diego, Salomaa, Veikko, Salonen, Jukka T, Salvetti, Massimo, Samoutian, Margarita, Sánchez-Abanto, Jose, Sandjaja, null, Sans, Susana, Marina, Loreto Santa, Santos, Diana A, Santos, Ina S, Santos, Lèlita C, Santos, Maria Paula, Santos, Osvaldo, Santos, Rute, Sanz, Sara Santo, Saramies, Jouko L, Sardinha, Luis B, Sarrafzadegan, Nizal, Sathish, Thirunavukkarasu, Saum, Kai-Uwe, Savva, Savva, Savy, Mathilde, Sawada, Norie, Sbaraini, Mariana, Scazufca, Marcia, Schaan, Beatriz D, Rosario, Angelika Schaffrath, Schargrodsky, Herman, Schienkiewitz, Anja, Schipf, Sabine, Schmidt, Carsten O, Schmidt, Ida Maria, Schnohr, Peter, Schöttker, Ben, Schramm, Sara, Schramm, Stine, Schröder, Helmut, Schultsz, Constance, Schutte, Aletta E, Sein, Aye Aye, Selamat, Rusidah, Sember, Vedrana, Sen, Abhijit, Senbanjo, Idowu O, Sepanlou, Sadaf G, Sequera, Victor, Serra-Majem, Lui, Servais, Jennifer, Ševcíková, Ludmila, Shalnova, Svetlana A, Shamah-Levy, Teresa, Shamshirgaran, Morteza, Shanthirani, Coimbatore Subramaniam, Sharafkhah, Maryam, Sharma, Sanjib K, Shaw, Jonathan E, Shayanrad, Amaneh, Shayesteh, Ali Akbar, Shengelia, Lela, Shi, Zumin, Shibuya, Kenji, Shimizu-Furusawa, Hana, Shin, Dong Wook, Shirani, Majid, Shiri, Rahman, Shrestha, Namuna, Si-Ramlee, Khairil, Siani, Alfonso, Siantar, Rosalynn, Sibai, Abla M, Silva, Antonio M, Silva, Diego Augusto Santo, Simon, Mary, Simons, Judith, Simons, Leon A, Sjöberg, Agneta, Sjöström, Michael, Skodje, Gry, Slowikowska-Hilczer, Jolanta, Slusarczyk, Przemyslaw, Smeeth, Liam, So, Hung-Kwan, Soares, Fernanda Cunha, Sobek, Grzegorz, Sobngwi, Eugène, Sodemann, Morten, Söderberg, Stefan, Soekatri, Moesijanti YE, Soemantri, Agustinu, Sofat, Reecha, Solfrizzi, Vincenzo, Somi, Mohammad Hossein, Sonestedt, Emily, Song, Yi, Sørensen, Thorkild IA, Sørgjerd, Elin P, Jérome, Charles Sossa, Soto-Rojas, Victoria E, Soumaré, Aïcha, Sovic, Slavica, Sparboe-Nilsen, Bente, Sparrenberger, Karen, Spinelli, Angela, Spiroski, Igor, Staessen, Jan A, Stamm, Hanspeter, Stathopoulou, Maria G, Staub, Kaspar, Stavreski, Bill, Steene-Johannessen, Jostein, Stehle, Peter, Stein, Aryeh D, Stergiou, George S, Stessman, Jochanan, Stevanovic, Ranko, Stieber, Jutta, Stöckl, Dori, Stocks, Tanja, Stokwiszewski, Jakub, Stoyanova, Ekaterina, Stratton, Gareth, Stronks, Karien, Strufaldi, Maria Wany, Sturua, Lela, Suárez-Medina, Ramón, Suka, Machi, Sun, Chien-An, Sundström, Johan, Sung, Yn-Tz, Sunyer, Jordi, Suriyawongpaisal, Paibul, Swinburn, Boyd A, Sy, Rody G, Syddall, Holly E, Sylva, René Charle, Szklo, Moyse, Szponar, Lucjan, Tai, E Shyong, Tammesoo, Mari-Lii, Tamosiunas, Abdona, Tan, Eng Joo, Tang, Xun, Tanrygulyyeva, Maya, Tanser, Frank, Tao, Yong, Tarawneh, Mohammed Rasoul, Tarp, Jakob, Tarqui-Mamani, Carolina B, Braunerová, Radka Taxová, Taylor, Anne, Taylor, Julie, Tchibindat, Félicité, Tebar, William R, Tell, Grethe S, Tello, Tania, Tham, Yih Chung, Thankappan, KR, Theobald, Holger, Theodoridis, Xenophon, Thijs, Lutgarde, Thomas, Nihal, Thuesen, Betina H, Tichá, Lubica, Timmermans, Erik J, Tjonneland, Anne, Tolonen, Hanna K, Tolstrup, Janne S, Topbas, Murat, Topór-Madry, Roman, Torheim, Liv Elin, Tormo, María José, Tornaritis, Michael J, Torrent, Matie, Torres-Collado, Laura, Toselli, Stefania, Touloumi, Giota, Traissac, Pierre, Tran, Thi Tuyet-Hanh, Trichopoulos, Dimitrio, Trichopoulou, Antonia, Trinh, Oanh TH, Trivedi, Atul, Tshepo, Lechaba, Tsigga, Maria, Tsugane, Shoichiro, Tuliakova, Azaliia M, Tulloch-Reid, Marshall K, Tullu, Fikru, Tuomainen, Tomi-Pekka, Tuomilehto, Jaakko, Turley, Maria L, Twig, Gilad, Tynelius, Per, Tzotzas, Themistokli, Tzourio, Christophe, Ueda, Peter, Ugel, Eunice, Ukoli, Flora AM, Ulmer, Hanno, Unal, Belgin, Usupova, Zhamyila, Uusitalo, Hannu MT, Uysal, Nalan, Vaitkeviciute, Justina, Valdivia, Gonzalo, Vale, Susana, Valvi, Damaskini, van Dam, Rob M, Van der Heyden, Johan, van der Schouw, Yvonne T, Van Herck, Koen, Van Minh, Hoang, Van Schoor, Natasja M, van Valkengoed, Irene GM, Vanderschueren, Dirk, Vanuzzo, Diego, Varbo, Anette, Varela-Moreiras, Gregorio, Varona-Pérez, Patricia, Vasan, Senthil K, Vega, Toma, Veidebaum, Tooma, Velasquez-Melendez, Gustavo, Velika, Biruta, Veronesi, Giovanni, Verschuren, WM Monique, Victora, Cesar G, Viegi, Giovanni, Viet, Lucie, Villalpando, Salvador, Vineis, Paolo, Vioque, Jesu, Virtanen, Jyrki K, Visser, Marjolein, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vladulescu, Mihaela, Vlasoff, Tiina, Vocanec, Dorja, Vollenweider, Peter, Völzke, Henry, Voutilainen, Ari, Voutilainen, Sari, Vrijheid, Martine, Vrijkotte, Tanja GM, Wade, Alisha N, Wagner, Aline, Waldhör, Thoma, Walton, Janette, Wambiya, Elvis OA, Bebakar, Wan Mohamad Wan, Mohamud, Wan Nazaimoon Wan, de Souza Wanderley Júnior, Rildo, Wang, Ming-Dong, Wang, Ningli, Wang, Qian, Wang, Xiangjun, Wang, Ya Xing, Wang, Ying-Wei, Wannamethee, S Goya, Wareham, Nichola, Weber, Adelheid, Wedderkopp, Niel, Weerasekera, Deepa, Weghuber, Daniel, Wei, Wenbin, Weres, Aneta, Werner, Bo, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wiecek, Andrzej, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Julianne, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong-McClure, Roy A, Wong, Andrew, Wong, Jyh Eiin, Wong, Tien Yin, Woo, Jean, Woodward, Mark, Wu, Frederick C, Wu, Jianfeng, Wu, Li Juan, Wu, Shouling, Xu, Haiquan, Xu, Liang, Yaacob, Nor Azwany, Yamborisut, Uruwan, Yan, Weili, Yang, Ling, Yang, Xiaoguang, Yang, Yang, Yardim, Nazan, Yaseri, Mehdi, Yasuharu, Tabara, Ye, Xingwang, Yiallouros, Panayiotis K, Yoosefi, Moein, Yoshihara, Akihiro, You, Qi Sheng, You, San-Lin, Younger-Coleman, Novie O, Md Yusof, Safiah, Yusoff, Ahmad Faudzi, Zaccagni, Luciana, Zafiropulos, Vassili, Zainuddin, Ahmad A, Zakavi, Seyed Rasoul, Zamani, Farhad, Zambon, Sabina, Zampelas, Antoni, Zamrazilová, Hana, Zapata, Maria Elisa, Zargar, Abdul Hamid, Ko Zaw, Ko, Zdrojewski, Tomasz, Zejglicova, Kristyna, Vrkic, Tajana Zeljkovic, Zeng, Yi, Zhang, Luxia, Zhang, Zhen-Yu, Zhao, Dong, Zhao, Ming-Hui, Zhao, Wenhua, Zhen, Shiqi, Zheng, Wei, Zheng, Yingfeng, Zholdin, Bekbolat, Zhou, Maigeng, Zhu, Dan, Zins, Marie, Zitt, Emanuel, Zocalo, Yanina, Cisneros, Julio Zuñiga, Zuziak, Monika, Ezzati, Majid, Filippi, Sarah, Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Université Paris Cité (UPCité), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)
Subjects: Population -- Health aspects, Leanness, Baixo peso/Underweight, none, Double burden, alipainoisuus, tulotaso, global health, systematic analysis, Sedentary behaviors, RC1200, Prospective associations, 0302 clinical medicine, underweight, nälänhätä, Biology (General), skin and connective tissue diseases, Children, ComputingMilieux_MISCELLANEOUS, Body mass index, Human Nutrition & Health, education.field_of_study, Humane Voeding & Gezondheid, ylipaino, General Medicine, kansainvälinen vertailu, 3. Good health, World health, Medicine, A100 Pre-clinical Medicine, Population distribution, medicine.medical_specialty, QH301-705.5, Science, Socio-culturale, Nursing, Social sciences, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Thinness, SDG 3 - Good Health and Well-being, BMI, epidemiology, obesity, None, Humans, Obesidade/Obesity, SDG 2 - Zero Hunger, education, VLAG, US adults, Omvårdnad, body mass index, malnutrition, obesity, underweight, nutritional and metabolic diseases, medicine.disease, terveellisyys, Obesity, Faculdade de Ciências Sociais, Body Mass Index, Prevalence, Risk Factors, General Biochemistry, WIAS, lihavuus, RA, Demography, N.A, double burden, Settore MED/09 - Medicina Interna, alueelliset erot, Nutrition and Disease, Animal Nutrition, [SDV]Life Sciences [q-bio], Medizin, 030204 cardiovascular system & hematology, 0601 Biochemistry and Cell Biology, Change distribution of body mass index, RA0421, Voeding en Ziekte, Epidemiology, Medicine and Health Sciences, Global health, Índice de massa corporal/Body Mass Index, 030212 general & internal medicine, Underweight, painoindeksi, 2. Zero hunger, General Neuroscience, aliravitsemus, elintarvikkeet, health, Public Health, Global Health, Social Medicine and Epidemiology, Diervoeding, 3142 Public health care science, environmental and occupational health, purl.org/pe-repo/ocde/ford#3.01.03 [https], Chinese adults, pooled analysis, medicine.symptom, Diet quality, B120 Physiology, Research Article, trends, purl.org/pe-repo/ocde/ford#1.06.03 [https], prevalence, Population, Mothers, Genetics and Molecular Biology, 3121 Internal medicine, medicine, Life Science, ddc:610, 3125 Otorhinolaryngology, ophthalmology, kehonkoostumus, Nutrition, Australian adults, General Immunology and Microbiology, purl.org/pe-repo/ocde/ford#3.01.04 [https], Ciências sociais, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Malnutrition, Epidemiology and Global Health, sense organs, Estilos de Vida e Impacto na Saúde
Abstract: From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions., Wellcome Trust, Medical Research Council, peer-reviewed
Published: 2021

16. Could Physical Fitness Be Considered as a Protective Social Factor Associated with Bridging the Cognitive Gap Related to School Vulnerability in Adolescents? The Cogni-Action Project

Author: Jessica Ibarra-Mora, Nicolas Aguilar-Farias, Carlos Cristi-Montero, Gerson Ferrari, Anelise Reis Gaya, Patricio Solis-Urra, Kabir P. Sadarangani, José Castro-Piñero, and Fernando Rodríguez-Rodríguez
Subjects: cognition, Mediation (statistics), Adolescent, poverty, Health, Toxicology and Mutagenesis, Physical fitness, Vulnerability, Vulnerable populations, physical activity, Article, Cognition, children, Humans, Effects of sleep deprivation on cognitive performance, Social Factors, Children, Poverty, Schools, business.industry, Physical activity, Public Health, Environmental and Occupational Health, Cardiorespiratory fitness, Cross-Sectional Studies, Cardiorespiratory Fitness, Physical Fitness, Medicine, Psychology, business, Body mass index, Neurocognitive, Demography, vulnerable populations
Abstract: Carlos Cristi-Montero received funding for the Cogni-Action Project from the National Commission for Scientific and Technological Research CONICYT/FONDECYT INICIACION 2016 grant No. 11160703 (Chile), and the National Research and Development Agency (ANID) from Chile-2019, Postdoctoral Grant No. 74200071., The first aim was to compare differences between school vulnerability groups, fitness levels, and their combination in adolescent cognitive performance. The second aim was to determine the mediation role of fitness in the association between school vulnerability and cognitive performance. A total of 912 Chilean adolescents aged 10–14 years participated in this study. The school vulnerability index (SVI) assigned by the Chilean Government was categorized into high-, mid-, or low-SVI. Adolescents were classified as fit or unfit according to their global fitness z-score computed from their cardiorespiratory (CRF), muscular (MF), and speed/agility fitness (SAF) adjusted for age and sex. A global cognitive scorewas estimated through eight tasks based on a neurocognitive battery. Covariance and mediation analyses were performed, adjusted for sex, schools, body mass index, and peak high velocity. Independent analyses showed that the higher SVI, the lower the cognitive performance (F(6,905) = 18.5; p < 0.001). Conversely, fit adolescents presented a higher cognitive performance than their unfit peers (F(5,906) = 8.93; p < 0.001). The combined analysis found cognitive differences between fit and unfit adolescents in both the high- and mid-SVI levels (Cohen’s d = 0.32). No differences were found between fit participants belonging to higher SVI groups and unfit participants belonging to lower SVI groups. Mediation percentages of 9.0%, 5.6%, 7.1%, and 2.8% were observed for the global fitness score, CRF, MF, and SAF, respectively. The mediation effect was significant between lowwith mid-high-SVI levels but not between mid- and high-SVI levels. These findings suggest that an adequate physical fitness level should be deemed a protective social factor associated with bridging the cognitive gap linked to school vulnerability in adolescents. This favourable influence seems to be most significant in adolescents belonging to a more adverse social background., National Commission for Scientific and Technological Research CONICYT/FONDECYT INICIACION (Chile) 11160703, National Research and Development Agency (ANID) from Chile 74200071
Published: 2021

17. Cardiorespiratory Fitness and Muscular Strength Moderates the Relationship between

Author: Pâmela Ferreira, Todendi, Caroline, Brand, João Francisco, de Castro Silveira, Ryan Donald, Burns, J Alfredo, Martínez, Marilu, Fiegenbaum, Anelise, Reis Gaya, Jane Dagmar, Pollo Renner, Cézane Priscila, Reuter, and Andréia Rosane, de Moura Valim
Subjects: obesity, Adolescent, Article, Body Mass Index, Fibronectins, Cross-Sectional Studies, Cardiorespiratory Fitness, children, Physical Fitness, physical fitness, Humans, genetics, Muscle Strength, Obesity, adolescents, Waist Circumference, Child, Adiposity
Abstract: The human locus FNDC5 rs16835198 contributes positively to anthropometric phenotypes in children and adolescents. However, the role of specific components of physical fitness in this relationship is not known. The present study aimed to verify the moderator role of cardiorespiratory fitness (CRF) and muscular strength in the relationship between rs16835198 polymorphism FNDC5 and adiposity in children and adolescents. This cross-sectional study was carried out by genotyping the rs16835198 FNDC5 polymorphism in 1701 children and adolescents (mean age 11.73 ± 2.75 years). Obesity was assessed using waist circumference and body mass index (BMI) z-scores. To evaluate CRF and muscular strength, the 6 min run/walk test and lower limb strength (LLS) were used. Linear regression models were applied, and all analyses were adjusted for age, sex, skin color, living area, and school type. A significant interaction term for CRF (p = 0.038) and LLS (p = 0.040) × rs16835198 FNDC5 with WC was identified. Regarding BMI, a significant interaction term for CRF (p = 0.007) and LLS (p = 0.044) × rs16835198 FNDC5 was observed. Moreover, medium and high CRF and LLS levels protected against higher WC and BMI. In conclusion, adiposity levels of children and adolescents with a genetic predisposition to obesity might be modified by improving CRF and muscular strength.
Published: 2021

18. Exercise in school Physical Education increase bone mineral content and density: Systematic review and meta-analysis

Author: Adroaldo Cezar Araujo Gaya, Michael J. Duncan, Anelise Reis Gaya, Antonio García-Hermoso, Augusto Pedretti, Clarice Martins, and Júlio Brugnara Mello
Subjects: Male, medicine.medical_specialty, Adolescent, Psychological intervention, Physical Therapy, Sports Therapy and Rehabilitation, Subgroup analysis, Physical exercise, Physical education, Bone Density, Medicine, Humans, Orthopedics and Sports Medicine, Child, Exercise, Femoral neck, Physical Education and Training, business.industry, Femur Neck, General Medicine, Confidence interval, Exercise Therapy, medicine.anatomical_structure, Meta-analysis, Physical therapy, Bone mineral content, Female, business
Abstract: This systematic review and meta-analysis aimed to evaluate the effectiveness of interventions through Physical Education (PE) exercises on bone mineral content (BMC) and density (BMD) of children and adolescents. The research was conducted using the online electronic databases PubMed, Science Direct, Web of Science and Scopus (March 2021). The analysis was restricted to school-based studies that examined the effect of PE interventions on BMC and BMD in schoolchildren (
Published: 2021

19. BMI Fails to Reflect the Developmental Changes in Body Fatness between Boys and Girls during Adolescence

Author: Jorge Mota, Alan M. Nevill, Michael J. Duncan, Caroline Brand, Anelise Reis Gaya, Cézane Priscila Reuter, and Jane Dagmar Pollo Renner
Subjects: 0301 basic medicine, Male, obesity, Adolescent, Crianças, Health, Toxicology and Mutagenesis, growth, 030209 endocrinology & metabolism, Growth, Age and sex, Body Mass Index, paediatrics, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, overweight, Statistical analysis, Obesity, Child, Adolescentes, Adiposity, Analysis of covariance, Índice de massa corporal, 030109 nutrition & dietetics, anthropometry, Anthropometry, business.industry, Brief Report, Percentage body fat, Public Health, Environmental and Occupational Health, Body fatness, Paediatrics, Overweight, Cross-Sectional Studies, Obesidade, Adipose Tissue, Female, Analysis of variance, business, Body mass index, Demography, Antropometria
Abstract: Body mass index (BMI) is thought to reflect excess adiposity in both youth and adults alike. However, the association between BMI and fatness varies, especially as children grow into adults. Thus, the present study sought to address this issue by characterizing how BMI reflects age and sex differences in body fatness in 7–16-year-old children. Methods: This cross-sectional study was conducted with 2150 children and adolescents, aged 7 to 16 years from the city of Santa Cruz do Sul, Brazil. BMI (kg/m2), and percentage body fat, using tricipital and subscapular folds, were assessed. For statistical analysis, ANOVA and ANCOVA were used. Results: When considered in isolation, there was no significant interaction in the age-by-sex differences in BMI (p = 0.69). However, when we controlled for percent body fatness, the analysis revealed considerable age-by-sex differences in BMI (p < 0.001). Conclusion: For the same body fat (%), there are no differences in BMI in children
Published: 2021

20. Responsiveness on metabolic syndrome criteria and hepatic parameters after 12 weeks and 24 weeks of multidisciplinary intervention in overweight adolescents

Author: W.A. Lopes, Maiara Cristina Tadiotto, Neiva Leite, Patricia Ribeiro Paes Corazza, Anelise Reis Gaya, F J de Menezes Junior, Gerusa E Milano-Gai, Jorge Mota, M E C Carli, Rosana Bento Radominski, and Caroline Brand
Subjects: Male, medicine.medical_specialty, Pediatric Obesity, Randomization, Adolescent, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Physical exercise, Overweight, Statistics, Nonparametric, Body Mass Index, Endocrinology, Liver Function Tests, Risk Factors, Internal medicine, medicine, Humans, Child, Metabolic Syndrome, Analysis of Variance, business.industry, Insulin, Anthropometry, medicine.disease, Blood pressure, Liver, Female, Analysis of variance, medicine.symptom, Metabolic syndrome, business, Brazil
Abstract: This study aimed to evaluate the effect and individual responsiveness after 12 (12wk) and 24 weeks (24wk) of physical exercise (PE) and nutritional guidance (NG) on metabolic syndrome (MetS) criteria and hepatic parameters in overweight adolescents. The study comprised 94 overweight adolescents, aged between 10 and 16 years old, from both sexes, allocated into groups: PE and NG (PENGG, n = 64) and control with NG (NGCG, n = 30). Variables were collected at baseline, 12wk, and 24wk. Weight, height, abdominal circumference (AC), blood pressure, and peak oxygen consumption (VO2peak), as well as insulin, triglycerides (TAG), high-density lipoprotein (HDL-c), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were evaluated. HOMA-IR and QUICKI were calculated. PE session consisted of 45 min of indoor cycling, 45 min of walking, and 20 min of stretching, three times a week. The NG consisted of three collective sessions in the first 12wk. Anova, effect size, and prevalence of responders were used for statistical analysis. The PENGG12wk reduced anthropometric and metabolic measurements, while increased VO2peak and HDL-c. The PEG24wk promoted anthropometric, blood pressure, metabolic, and VO2peak improvements, but participants without PE returned to pre-exercise status and presented worsening AST and ALT concentrations. Frequencies of respondents in PENGG12wk versus (vs) NGCG12wk were, respectively, AC (69.1% vs 17.6%, p
Published: 2021

21. Sleep-related problems and eating habits during COVID-19 lockdown in a southern Brazilian youth sample

Author: Anelise Reis Gaya, José Francisco López-Gil, Rafael Gomes Sentone, Hallyne Bergamini Silva Caetano, Cristiano Israel Caetano, Cézane Priscila Reuter, and Javier Brazo-Sayavera
Subjects: Coronavirus disease 2019 (COVID-19), Adolescent, SARS-CoV-2, COVID-19, Sample (statistics), Healthy eating, General Medicine, Feeding Behavior, Logistic regression, Sleep in non-human animals, Dyssomnias, Snowball sampling, Child, Preschool, Surveys and Questionnaires, Communicable Disease Control, Lower prevalence, Humans, Psychology, Eating habits, Child, Brazil, Demography
Abstract: The pandemic has affected children's behaviors and this fact has an effect on their healthy habits, such as sleep and diet. The aim of the current study was to determinate the prevalence of sleep-related problems and its relationship with eating habits in children from the south of Brazil during the pandemic. Parents/legal guardians of 3-17 years old participants responded to a online survey distributed using the snowball sampling strategy in Brazil. The survey was conducted in April, 2020. Participants were asked for their sleep duration and sleep-related problems, as well as for their eating habits. Logistic regressions were performed to analyze the relationship between sleep-related problems and eating habits. 495 participants were included in the analysis. 48.8% of participants reported sleep-related problems with 12.3% not meeting the sleep guidelines. Moreover, participants reported eating fruits or vegetables and sweets over four and three per week, respectively. Different associations were found between varibles of sleep and eating habits. Those participants with healthy eating habits showed a lower prevalence of sleep-related problems.
Published: 2021

22. Adiposity and adipocytokines: the moderator role of cardiorespiratory fitness and pubertal stage in girls

Author: Cláudia Regina Cavaglieri, Wendell Arthur Lopes, Larissa Rosa da Silva, Jorge Mota, Anelise Reis Gaya, Arieli Fernandes Dias, Neiva Leite, Adroaldo Cezar Araujo Gaya, and Caroline Brand
Subjects: Leptin, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Adipokine, 030209 endocrinology & metabolism, Body Mass Index, 03 medical and health sciences, Pubertal stage, 0302 clinical medicine, Endocrinology, Internal medicine, Humans, Medicine, Child, Exercise, Adiposity, Adiponectin, business.industry, Puberty, Cardiorespiratory fitness, 030229 sport sciences, Anthropometry, medicine.disease, Obesity, Cross-Sectional Studies, Cardiorespiratory Fitness, Pediatrics, Perinatology and Child Health, Body Composition, Female, business, Body mass index
Abstract: BackgroundCardiorespiratory fitness (CRF) and pubertal stages have been related to many health outcomes, including obesity and adipocytokines. Thus, the present study aimed to analyze the moderator role of CRF and pubertal stage in the relationship between adiposity and adipocytokines in girls.MethodThis cross-sectional study was performed with 42 pre-pubertal girls aged from 7 to 11 years and 54 post-pubertal girls aged from 13 to 17 years. Blood samples were collected to determine the serum levels of leptin and adiponectin, and then the leptin/adiponectin ratio (L/A ratio) was calculated. CRF, anthropometric and body composition indicators were assessed. For statistical analysis, descriptive statistics and several linear regression models were used. The moderation analysis was tested using the PROCESS macro.ResultsAn interaction between body mass index (BMI) and CRF (β: –0.70; confidence interval [CI]: –1.29, –0.12), as well as between BMI and pubertal stage (β: 0.79; CI: 0.28, 1.30) with leptin, was found. Regarding the L/A ratio, an interaction was found only in BMI × CRF (β: –0.56; CI: –1.06, –0.06). Using a combined interaction (CRF and pubertal stage), the results showed a positive association between BMI with leptin and L/A ratio only in low CRF, pre-pubertal and post-pubertal stages.ConclusionThis study suggests a protective role of high levels of CRF in the relationship between BMI and adipocytokines. Despite the effect of pubertal stage, the results suggest that youth should be engaged in physical activity in order to improve CRF levels and consequently improve cardiometabolic health.
Published: 2019

23. SCHOOL-TIME MOVEMENT BEHAVIOURS AND FUNDAMENTAL MOVEMENT SKILLS IN PRESCHOOLERS: AN ISOTEMPORAL REALLOCATION ANALYSIS

Author: Cain C T Clark, Michael J. Duncan, Anelise Reis Gaya, Clarice Martins, Rafael Miranda Tassitano, and Anastácio Neco de Souza Filho
Subjects: Male, Schools, Movement (music), Infant, Experimental and Cognitive Psychology, 030229 sport sciences, Sensory Systems, 03 medical and health sciences, Cross-Sectional Studies, 0302 clinical medicine, Motor Skills, Child, Preschool, Accelerometry, Key (cryptography), Humans, Female, 030212 general & internal medicine, Psychology, Brazil, Cognitive psychology
Abstract: BACKGROUND: Little is known on how relocations of time spent in different movement behaviours during pre-school hours could relate to preschooler’s fundamental movement skills (FMS), a key predictor of later physical activity (PA). Thus, the aim of this study was to examine whether the school-time composition was associated with FMS; and to investigate predicted differences in FMS when a fixed duration of time was reallocated from one activity behaviour to another in preschool children. METHODS: A cross-sectional representative data of an intervention study with Brazilian low-income preschoolers. Two hundred and four preschoolers of both sexes (4.5±0.8 years-old; 101boys) provided 10 hours of school-time objectively assessed PA and sedentary behaviour (SB) data (Actigraph wGT3X), and FMS assessments (TGMD-2). Association of school-time composition of movement behaviuors with FMS and its reallocations during school-time was explored using compositional analysis in R (version 1.40-1), robCompositions (version 0.92-7), and lmtest (version 0.9-35) packages. RESULTS: The isotemporal reallocation showed that for manipulative skills, an increasing pattern was observed (0.14, 0.28, and 0.42-units) when reallocating 5, 10 and 15 minutes, respectively, from light PA to SB. CONCLUSIONS: The current study highlights that school-time composition is a significant predictor of FMS. Moreover, a modest increase in SB, at the expense of LPA, during the school-time may elicit a positive change in manipulative skills.
Published: 2021

24. Physical fitness and its association with cognitive performance in Chilean schoolchildren: the Cogni-Action Project

Author: Patricio Solis-Urra, Javier Sanchez-Martinez, Gerson Ferrari, Anelise Reis Gaya, Kabir P. Sadarangani, Carlos Cristi-Montero, José Castro Piñero, Jorge Olivares-Arancibia, Fernando Rodríguez-Rodríguez, and Camila Felin Fochesatto
Subjects: Male, Aptidão física, Adolescent, Intelligence, Physical fitness, Healthy lifestyle, Physical Therapy, Sports Therapy and Rehabilitation, Neuropsychological Tests, 030204 cardiovascular system & hematology, Adolescents, Running, 03 medical and health sciences, 0302 clinical medicine, Cognition, Humans, Orthopedics and Sports Medicine, Muscle Strength, Effects of sleep deprivation on cognitive performance, Cognitive skill, Chile, Child, Adolescentes, Analysis of Variance, Schools, business.industry, Working memory, Força muscular, Muscle strength, Cognitive flexibility, Cardiorespiratory fitness, 030229 sport sciences, Estilo de vida saudável, Inhibition, Psychological, Cross-Sectional Studies, Memory, Short-Term, Cardiorespiratory Fitness, Physical Fitness, Female, business, Psychology, Neurocognitive, Cognição, Clinical psychology
Abstract: This study aimed to establish the association and differences in a diversity of cognitive domains according to cardiorespiratory fitness (CRF), muscular fitness (MF), and speed- agility fitness (S- AF) level in a large sample of Chilean schoolchildren. 1171 Chilean schoolchildren aged 10– 14years participated. CRF, MF, and S- AF were as-sessed through the ALPHA- fitness test battery. Cognition was evaluated through the NeuroCognitive Performance Test, which involved eight tests related to four main domains: cognitive flexibility (CF), working memory (WM), inhibitory control (IC), and intelligence (IN). Both global (multivariate) and individual (univariate) analyses were performed to determine the differences in cognitive functioning according to low- , middle- , and high- fitness level. The global analyses showed a significant main effect for CRF, F(16,940)=3.08, p.001 and MF groups, F(16,953)=2.30, p=.002, but not for S- AF, F(16,948)=1.37, p=.105. CRF shows a significant main effect in seven of eight tests, involving CF, WM, IC, and IN domains, whereas MF shows a significant main effect in five of eight tests without association with IN. SA- F shows a significant main effect only with IC. Statistical differences were found between the low- and middle/high- fitness groups but not between the middle- and high- fitness groups. At a global level, both CRF and MF seem to be associated with a higher cog-nitive profile in scholars; however, at an individual level, all fitness components show a favorable relationship to some cognitive domine. Then, future cognitive develop-ing strategies should consider all fitness components, prioritizing those low- fitness schoolchildren.
Published: 2021

25. Effects and responsiveness of a multicomponent intervention on body composition, physical fitness, and leptin in overweight/obese adolescents

Author: Jorge Mota, Cézane Priscila Reuter, Neiva Leite, Letícia de Borba Schneiders, Caroline Brand, Leticia Borfe, Cláudia Regina Cavaglieri, Jane Dagmar Pollo Renner, and Anelise Reis Gaya
Subjects: Leptin, medicine.medical_specialty, Pediatric Obesity, obesity, Waist, Youth, Adolescent, Health, Toxicology and Mutagenesis, Physical fitness, Inter-individual variability, 030209 endocrinology & metabolism, Physical exercise, Overweight, Exercício físico, Article, Body Mass Index, inter-individual variability, 03 medical and health sciences, 0302 clinical medicine, physical exercise, Internal medicine, medicine, Humans, Obesity, Cardiorespiratory fitness, Exercise, Adolescentes, youth, cardiorespiratory fitness, business.industry, Public Health, Environmental and Occupational Health, 030229 sport sciences, medicine.disease, Endocrinology, Obesidade, Physical Fitness, Body Composition, Medicine, medicine.symptom, Waist Circumference, business, Body mass index, Aptidão cardiorrespiratória
Abstract: Physical exercise reduces the biochemical markers of obesity, but the effects of multicomponent interventions on these markers should be explored. The present study aimed to elucidate how overweight/obese adolescents respond to a multicomponent program approach on body composition, physical fitness, and inflammatory markers, using a quasi-experimental study with 33 overweight/obesity adolescents (control group (CG) = 16, intervention group (IG) = 17). The intervention consisted of 24 weeks with physical exercises and nutritional and psychological guidance. Both groups were evaluated at the pre/post-intervention moments on body mass index (BMI), body fat (%Fat), waist circumference (WC), waist/hip ratio (WHR), waist-to-height ratio (WHtR), cardiorespiratory fitness (CRF), abdominal strength, flexibility, leptin, interleukin 6, interleukin 10, and tumor necrosis factor-alpha. Mixed-analysis of variance and generalized estimation equations were used for statistical analysis. There was an interaction effect between groups and time on %Fat (p = 0.002), WC (p = 0.023), WHR (p &lt, 0.001), WHtR (p = 0.035), CRF (p = 0.050), and leptin (p = 0.026). Adolescents were classified as 82.4% responders for %Fat, 70.6% for WC, 88.2% for WHR, and 70.6% for CRF. Further, there was an association between changes in %Fat (p = 0.033), WC (p = 0.032), and WHR (p = 0.033) between responders and non-responders with CRF in the IG. There was a positive effect on body composition, physical fitness, and leptin. In addition, reductions in body composition parameters were explained by CRF improvements.
Published: 2021

26. Physical fitness attenuates the genetic predisposition to obesity in children and adolescents

Author: Marilu Fiegenbaum, Andréia Rosane de Moura Valim, João Francisco de Castro Silveira, Caroline Brand, César Agostinis-Sobrinho, Ryan D. Burns, Cézane Priscila Reuter, Pâmela Ferreira Todendi, and Anelise Reis Gaya
Subjects: Male, Aptidão física, Pediatric Obesity, Adolescent, Crianças, Physical fitness, Psychological intervention, Physical Therapy, Sports Therapy and Rehabilitation, 030204 cardiovascular system & hematology, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Genetic predisposition, Genetics, Medicine, Humans, Orthopedics and Sports Medicine, Genetic Predisposition to Disease, Obesity, Muscle Strength, Risk factor, Child, Adolescentes, Índice de massa corporal, business.industry, Cardiorespiratory fitness, 030229 sport sciences, Moderation, medicine.disease, Genética, Childhood, Adolescence, Cross-Sectional Studies, Obesidade, Cardiorespiratory Fitness, Physical Fitness, Female, business, Body mass index, Demography
Abstract: Obesity is an important risk factor associated with non-communicable cardiometabolic diseases. Previous studies have indicated that children and adolescents with a predisposed genetic risk for obesity could benefit from an active lifestyle, but there are no studies investigating whether physical fitness moderates the association of genetics and obesity. The aim of this study was to verify the moderating role of physical fitness in the relationship between genetic risk score (GRS) and body mass index (BMI) in children and adolescents. This cross-sectional study was carried out with 1471 children and adolescents, aged between 6 and 17 years from Santa Cruz do Sul, Brazil. Weight and height were assessed to determine BMI. Physical fitness components (cardiorespiratory fitness [CRF], lower limb strength [LLS], upper limb strength, and abdominal strength) were evaluated. The GRS was based on previously associated obesity single-nucleotide polymorphism rs9939609 (FTO), rs6548238 (TMEM18), and rs16835198 (FNDC5). Moderation analyses were tested using linear regression models, and the interactions were represented by physical fitness components X GRS (categorical variable). All analyses were adjusted for skin color/ethnicity, sex, and sexual maturation. Significant interactions for CRF (P = 0.041), LLS (P = 0.041), and abdominal strength (P = 0.046) X 5 and 6 risk alleles with BMI were found only in adolescents. In addition, there was evidence that fitness components attenuated the high genetic predisposition to high BMI. Physical fitness components are moderators in the relationship between GRS and BMI in adolescents. These findings highlight the need for interventions targeting to improve this aspect, which is an important health indicator in all ages.
Published: 2020

27. Physical fitness as a moderator in the relationship between adiposity and cardiometabolic risk factors in children and adolescents

Author: Javier Brazo-Sayavera, Jane Dagmar Pollo Renner, Ana Paula Sehn, Jorge Mota, Anelise Reis Gaya, Cézane Priscila Reuter, and Caroline Brand
Subjects: Male, Waist, Adolescent, Physical fitness, 030209 endocrinology & metabolism, Physical Therapy, Sports Therapy and Rehabilitation, Overweight, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, Orthopedics and Sports Medicine, 030212 general & internal medicine, Obesity, Child, Lipoprotein cholesterol, Adiposity, Cardiometabolic risk, business.industry, Cardiometabolic Risk Factors, Cardiorespiratory fitness, Moderation, Cross-Sectional Studies, Normal weight, Cardiorespiratory Fitness, Physical Fitness, Female, medicine.symptom, Waist Circumference, business, Demography
Abstract: BACKGROUND The aim of this study was to verify the moderator role of physical fitness in the relationship between adiposity and cardiometabolic risk factors in normal weight and overweight/obese children and adolescents. METHODS Cross-sectional study comprising 2482 children and adolescents, aged 7-17 years. Physical fitness was evaluated according the procedures of Projeto Esporte Brazil, and waist circumference (WC) with an inelastic tape. Cardiometabolic risk score was defined by the z-score sum of glucose, total cholesterol, high-density lipoprotein cholesterol and low-density lipoprotein cholesterol. Moderation analysis was done through linear regression models. RESULTS Significant interaction term for cardiorespiratory fitness (CRF)×WC with cardiometabolic risk factors (P
Published: 2020

28. Child's body mass index and mother's obesity: the moderating role of physical fitness

Author: Caroline, Brand, Camila Felin, Fochesatto, Arieli Fernandes, Dias, Anelise Reis, Gaya, Clarice Maria, de Lucena Martins, Jane Dagmar Pollo, Renner, Cézane Priscila, Reuter, and Roya, Kelishadi
Subjects: Pediatric Obesity, Cross-Sectional Studies, Adolescent, Cardiorespiratory Fitness, Physical Fitness, Pregnancy, Humans, Mothers, Female, Child, Brazil, Body Mass Index
Abstract: The aim of this study was to verify the association between children's body mass index and their mother's obesity, considering children's physical fitness as a possible moderator. Cross-sectional study developed with 1842 children and adolescents, aged seven to 17 years, from Santa Cruz do Sul-RS, Brazil. Body weight and height were assessed to determine body mass index. Cardiorespiratory fitness was determined by the 6-min walk/run test and muscular strength through the lower limb strength test. Mother's perception of obesity was self-assessed. Moderation was tested through a SPSS program extension. Results indicated that higher children's body mass index (p 0.001) and lower levels of cardiorespiratory fitness (p = 0.001) and muscular strength (p = 0.035) were associated with mother's obesity. Likewise, higher body mass index (p 0.001) and lower cardiorespiratory fitness (p 0.001) in adolescents were associated with maternal obesity. Moreover, physical fitness moderates the relationship between body mass index and mother's obesity in children (cardiorespiratory fitness: β = - 0.006; 95% CI = (- 0.010, - 0.001); muscular strength: β = - 8.415; 95% CI = (- 12.526, - 4.304)) and in adolescents (cardiorespiratory fitness: β = - 0.004; 95% CI = (- 0.008, - 0.0008); muscular strength: β - 2.958; 95% CI = (- 5.615, - 0.030)).Conclusion: increasing physical fitness is an important strategy to protect youths from high body mass index, when their mothers are obese. What is Known: • Mother's obesity is associated with their children's body mass index. • Parents' obesity is associated with their children's physical fitness What is New: • Cardiorespiratory fitness and muscular strength are moderators in the relationship between mother's obesity and BMI of their children. • Children and adolescents with high cardiorespiratory fitness and muscular strength levels are protected against elevated body mass index, considering mother's obesity.
Published: 2020

29. Neighborhood environmental factors associated with leisure walking in adolescents

Author: Thiago Monteiro Mendes, Caroline Brand, Jorge Mota, Andreia N. Pizarro, Arieli Fernandes Dias, Anelise Reis Gaya, Camila Felin Fochesatto, Adroaldo Cezar Araujo Gaya, and Maria Paula Santos
Subjects: Male, Caminhada, Adolescent, Cross-sectional study, Poison control, environmental health, cross-sectional studies, socioeconomic factors, Ambiente construído, Walking, Young Adult, walking, Age Distribution, Leisure Activities, Residence Characteristics, Humans, Sports and Recreational Facilities, Sex Distribution, Built Environment, Students, Recreation, Socioeconomic status, Adolescentes, Built environment, Geography, lcsh:Public aspects of medicine, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, built environment, Land use mix, Cross-Sectional Studies, Residential density, Social Class, Fatores socioeconômicos, Socioeconomic Factors, Walkability, adolescent, Linear Models, Saúde ambiental, population characteristics, Female, Original Article, Self Report, human activities, Environmental Health, Brazil, Demography
Abstract: OBJECTIVE: To verify the associations of leisure walking with perceived and objective measures of neighborhood environmental factors stratified by gender and socioeconomic status (SES) in Brazilian adolescents. METHODS: Cross-sectional study with a random sample of 1,130 high school students (47.3% girls; aged 14 to 20 years old) from Porto Alegre, Brazil. Leisure walking and SES were self-reported by the adolescents. Perceived environmental factors were assessed through Neighborhood Environment Walkability Scale for Youth (NEWS-Y). Objective measures were evaluated using Geographic Information Systems, with road network calculated around the adolescent’s residential address, using 0.5km and 1.0km buffers. Data collection was carried out in 2017 and generalized linear regression models were used. RESULTS: Leisure walking was positively associated with access to services (0.5 km buffers [Odds ratio (OR) = 2.22] 1.0 km buffers [OR = 2.17]) and lower distance to parks and squares (0.5 km [OR=2.80] 1.0 km [OR = 2.73]) in girls from low SES. Residential density (0.5 km [OR = 1.57] 1.0 km [OR = 1.54]) and walkability index (0.5 km [OR = 1.17] 1.0 km [OR = 1.20]) were associated with leisure walking in girls from middle SES. Boys from low SES showed an inverse association between crime safety and leisure walking (0.5 km [OR = 0.59] 1.0 km [OR = 0.63]). Neighborhood recreation facilities was positively associated with leisure walking in middle SES (0.5 km [OR = 1.55] 1.0 km [OR = 1.60]). Land use mix (0.5 km [OR = 1.81] 1.0 km [OR = 1.81]), neighborhood recreation facilities (0.5 km [OR = 2.32] 1.0 km [OR = 2.28]) and places for walking (0.5 km [OR=2.07] 1.0 km [OR=2.22]) were positively associated with leisure walking in high SES. CONCLUSION: Environmental factors (objectively and subjectively measured) and leisure walking show association in boys and girls of different SES.
Published: 2020

30. Relationship between insulin resistance and adipocytokines: the mediator role of adiposity in children

Author: Álvaro Reischak de Oliveira, Anelise Reis Gaya, César Agostinis-Sobrinho, Juliano Boufleur Farinha, Arieli Fernandes Dias, Adroaldo Cezar Araujo Gaya, Francesco Pinto Boeno, Jorge Mota, and Caroline Brand
Subjects: Leptin, Aging, medicine.medical_specialty, Aptidão física, Physiology, Epidemiology, Fatness, Adipokine, Mediator, Insulin resistance, Leptina, Internal medicine, Genetics, medicine, Humans, Child, Adiposity, Adiponectin, business.industry, digestive, oral, and skin physiology, Public Health, Environmental and Occupational Health, Cardiorespiratory fitness, Physical fitness, medicine.disease, Obesity, Endocrinology, Cross-Sectional Studies, Obesidade, Adipose Tissue, Student, Insulin Resistance, business, Estudantes, hormones, hormone substitutes, and hormone antagonists, Adiponectina, Brazil
Abstract: Background: Leptin and adiponectin interact with each other in the modulation of obesity and insulin resistance (IR) and it is also important to consider the role of cardiorespiratory and muscular fitness in these relationships. Aim: To analyse the relationship between IR with adipocytokines in children, and to test the mediation effect of %BF (percentage of body fat) in the association of IR with leptin, adiponectin, and L/A ratio. Subjects and methods: This cross-sectional study comprised a sample of 150 schoolchildren, aged 6–11 years, from school in Porto Alegre, Brazil. The following variables were evaluated: cardiorespiratory fitness (CRF), muscular fitness (MF), percentage of body fat (%BF), and biochemical variables (leptin, adiponectin, glucose, and insulin). Results: IR was associated with leptin and L/A ratio, after adjustments for age, sex, sexual maturation, and CRF. When adjusted for age, sex, sexual maturation, and MF, an association was found between IR with leptin and L/A ratio. Moreover, %BF was a mediator in the association between IR and leptin, as well as IR and L/A ratio, explaining 54% and 57% of these associations, respectively. Conclusion: Leptin and L/A ratio are positively associated with IR after adjustments. Also, %BF is a mediator in the associations between IR and leptin and L/A ratio.
Published: 2020

31. Meeting international screen-time guidelines is associated with healthy dietary patterns in Spanish schoolchildren

Author: Miguel Angelo dos Santos Duarte Junior, Juan Luis Yuste Lucas, Anelise Reis Gaya, and José Francisco López Gil
Subjects: 0301 basic medicine, Male, Internationality, Crianças, Medicine (miscellaneous), Healthy eating, Sedentary behaviorn, 0302 clinical medicine, Vegetables, Odds Ratio, Nuts, Child, Children, Nutrition and Dietetics, Fishes, Comportamiento sedentario, Dietary pattern, Patrones de alimentación, %22">Fish , Female, Guideline Adherence, Diet, Healthy, medicine.medical_specialty, Adolescent, 030209 endocrinology & metabolism, Dieta mediterrânea, Estilo de vida, Screen Time, 03 medical and health sciences, Screen time, Feeding patterns, Sex Factors, Mediterranean diet, medicine, Confidence Intervals, Animals, Humans, Niños, Gynecology, 030109 nutrition & dietetics, business.industry, Estudio transversal, Feeding Behavior, Lifestyle, Comportamento sedentário, Dieta mediterránea, Sedentary behavior, Cross-Sectional Studies, Spain, Fruits and vegetables, Fruit, business, Hábitos alimentares
Abstract: espanolObjetivo: el objetivo de esta investigacion fue explorar la relacion entre los habitos de alimentacion y el cumplimiento de las recomendaciones de tiempo de pantalla en escolares espanoles. Material y metodos: se realizo un estudio transversal y asociativo con un total de 370 escolares (44,9 % ninas) de 6 a 13 anos (8,7 ± 1,8). Resultados: en los ninos, aquellos que no cumplian con las recomendaciones presentaron menos probabilidades de comer verduras regularmente (OR = 0,50; IC 95 % = 0,28-0,89) y de ingerirlas mas de una vez al dia (OR = 0,43; IC 95 % = 0,22-0,85). En las ninas se observo que las que no cumplian las recomendaciones presentaban una menor probabilidad de comer una pieza de fruta (OR = 0,43; IC 95 % = 0,19-0,99) asi como una segunda pieza (OR = 0,22; IC 95 % = 0,22-0,81), verduras mas de una vez al dia (OR = 0,39; IC 95 % = 0,19-0,80), pescado (al menos 2-3 veces por semana) (OR = 0,40; IC 95 % = 0,20-0,78) y frutos secos (al menos 2 o 3 veces por semana) (OR = 0,46; IC 95 % = 0,24-0,87). Conclusion: algunos patrones de alimentacion saludable, como el consumo de frutas y verduras, parecen ser mas prevalentes en los ninos que cumplen con las recomendaciones internacionales de tiempo de pantalla. EnglishObjective: the aim of this research was to explore the relationship between dietary pattern habits and compliance with screen-time guidelines in Spanish schoolchildren. Material and methods: a cross-sectional and associative study was performed in a total of 370 schoolchildren (44.9 % girls) aged 6-13 (8.7 ± 1.8) years. Results: for boys, those who did not meet these guidelines presented lower chances of eating vegetables regularly (OR = 0.50; 95 % CI = 0.28-0.89) or more than once a day (OR = 0.43; 95 % CI = 0.22-0.85). In girls, it was observed that those who did not meet the guidelines presented a lower probability of eating one piece of fruit (OR = 0.43; 95 % CI = 0.19-0.99) as well as a second piece (OR = 0.22; 95 % CI = 0.22-0.81), vegetables more than once a day (OR = 0.39; 95 % CI = 0.19-0.80), fish (at least 2-3 times/week) (OR = 0.40; 95 % CI = 0.20-0.78) and nuts (at least 2 or 3 times per week) (OR = 0.46; 95 % = 0.24-0.87). Conclusion: some healthy eating patterns, such as the consumption of fruits and vegetables, appeared to be more prevalent in those children who met the international screen-time guidelines.
Published: 2020

32. Adherencia a la Dieta Atlántica del Sur de Europa y condiciones físicas en el índice aterogénico de plasma en adolescentes

Author: Adroaldo Cezar Araujo Gaya, Sigute Norkiene, Luís Lopes, Rute Santos, Carla Moreira, Sandra Abreu, Jorge Mota, Anelise Reis Gaya, César Agostinis-Sobrinho, Caroline Brand, and Arieli Fernandes Dias
Subjects: Male, medicine.medical_specialty, Adolescent, Cross-sectional study, Physical fitness, Triglicerídeos, Triglycerides blood, diet, cardiorespiratory fitness, high-density lipoproteins, triglycerides, adolescent, High-density Lipoproteins, Triglicéridos, Pubertal stage, Lipoproteínas de Alta Densidade, Parental education, Lipoproteinas, Internal medicine, Humans, Medicine, Cardiorespiratory fitness, High-density lipoproteins, Adolescentes, Adolescente, Shuttle run test, Triglycerides, business.industry, Dieta alimentar, Public Health, Environmental and Occupational Health, Food frequency questionnaire, Diet, Cross-Sectional Studies, Cardiorespiratory Fitness, Capacidad Cardiovascular, Adolescent Behavior, Physical Fitness, Dieta, Female, Lipoproteínas de Alta Densidad, Public aspects of medicine, RA1-1270, Lipoproteins, HDL, business, Brazil, Aptidão cardiorrespiratória
Abstract: We sought (i) to evaluate the associations of cardiorespiratory fitness (CRF), muscular fitness (MF) and Southern European Atlantic Diet (SEADiet) with atherogenic index of plasma (AIP) and (ii) to investigate de combined association of MF, CRF and SEADiet on AIP in adolescents. A cross-sectional school-based study was conducted on 493 adolescents (285 girls and 208 boys) aged 15-18 years, from the Portuguese Azorean Archipelago. CRF was measured by shuttle run test and MF by curl up and push up tests. Adherence to SEADiet was assessed with a semi-quantitative food frequency questionnaire (FFQ). The AIP was estimated as log (TG/HDL-C). Measures of pubertal stage and socioeconomic status were assessed. Linear regression showed a significant inverse association between MF (standardized β = -0.165; p < 0.001), CRF (standardized β = -0.081; p < 0.030) and SEADiet (standardized β = -0.081; p < 0.045) with AIP, after adjustments for age, sex, pubertal stage and parental education. Furthermore, participants classified with an optimal as well as those with low adherence to a SEADiet but with LowMF/LowCRF had on average the highest AIP (F(7.482) = 3.270; p = 0.002). Moreover, optimal SEADiet with HighMF/HighCRF group showed the lowest AIP when compared with those with low adherence to a SEADiet with HighMF/HighCRF group (p = 0.03). AIP is inversely associated with MF, CRF and SEADiet. The low MF combined with a low CRF levels seems to overcome the potential healthy effect of having an optimal adherence to the SEADiet on AIP. However, an optimal adherence to SEADiet seems to improve the AIP in those adolescents with high fitness levels. Resumo: O estudo teve como objetivos: (i) avaliar as associações entre a aptidão cardiorrespiratória (ACR), aptidão muscular (AM) e Dieta Atlântica do Sul da Europa (SEADiet) e o índice aterogênico do plasma (IAP) e (ii) investigar a associação combinada entre AM, ACR e SEADiet e IAP em adolescentes. Foi realizado um estudo transversal de base escolar em uma amostra de 493 adolescentes (285 do sexo feminino), entre 15 e 18 anos de idade, nos Arquipélago dos Açores, Portugal. A ACR foi medida pelo teste aeróbico de corrida de vai-e-vem e a AM pelos testes de abdominal modificado e de flexão. A adesão ao SEADiet foi avaliada através de um questionário semi-quantitativo de frequência alimentar. O IAP foi calculado como log(TG/HDL-C). Foram avaliadas as medidas de estágio de puberdade e de nível socioeconômico. A regressão linear revelou uma associação inversa significativa entre AM (β padronizado = -0,165; p < 0,001), ACR (β padronizado = -0,081; p < 0,030) e SEADiet (β padronizado = -0,081; p < 0,045) e IAP, depois de ajustar para idade, sexo, estágio de puberdade e escolaridade dos pais. Além disso, os participantes classificados como adesão excelente ou baixa ao padrão alimentar SEADiet mas com BaixaAM/BaixaACR, tiveram, em média, os maiores níveis de IAP (F(7,482) = 3,270; p = 0,002). O grupo com adesão excelente ao SEADiet e AltaAM/AltaACR mostrou IAP mais baixo, comparado com o grupo com baixa adesão ao padrão alimentar SEADiet e AltaAM/AltaACR (p = 0,03). O IAP está associado inversamente com AM, ACR e SEADiet. Os níveis baixos de AM e ACR parecem contrabalançar o efeito saudável potencial da adesão excelente ao padrão alimentar SEADiet sobre o IAP. Entretanto, a adesão excelente ao SEADiet parece melhorar o IAP nos adolescentes com níveis altos de aptidão física. Resumen: Nuestro objetivo (i) fue evaluar las asociaciones de las condiciones cardiorrespiratorias (CRF), musculares (MF) y de la Dieta Atlántica del Sur de Europa (SEADiet), con el índice aterogénico de plasma (AIP), así como (ii) investigar la asociación combinada de MF, CRF y SEADiet en el AIP en adolescentes. Se trata de un estudio transversal, basado escolares, que se dirigió a 493 adolescentes (285 niñas), con edades comprendidas entre los 15 a 18 años, procedentes del archipiélago portugués de las Azores. Las CRF se midieron mediante una prueba de sprint y las MF mediante pruebas con flexiones y abdominales. La adherencia a la SEADiet se evaluó con un cuestionario semicuantitativo sobre la frecuencia de las comidas. El AIP se calculó como log (TG/HDL-C). Se evaluaron las medidas de la fase puberal y el estatus socioeconómico. La regresión lineal mostró una asociación significativa inversa entre MF (β estandarizado = -0,165; p < 0,001), CRF (β estandarizado = -0,081; p < 0,030) y SEADiet (β estandarizado = -0,081; p < 0,045) con el AIP, tras los ajustes por edad, sexo, fase puberal y educación parental. Asimismo, los participantes clasificados con una adherencia muy buena, así como los que tuvieron una baja adherencia a la SEADiet, pero con BajasMF/BajasCRF contaron con el promedio más alto en el AIP (F(7.482) = 3.270; p = 0,002). Además, el grupo con una muy buena SEADiet con AltasMF/AltasCRF mostró el más bajo AIP, cuando se compara con el grupo que tenía una baja adherencia a la SEADiet con AltasMF/AltasCRF (p = 0.03). El AIP está inversamente asociado con MF, CRF y SEADiet. La baja MF, combinada con los niveles bajos de CRF, parece superar el efecto potencial saludable de contar con una muy buena adherencia a la SEADiet en el AIP. No obstante, una muy buena adherencia a la SEADiet parece mejorar el AIP en aquellos adolescentes con altos niveles de condición física.
Published: 2019

33. Muscular fitness, Southern European Atlantic Diet and inflammation in adolescents. Azorean Physical Activity and Health Study II

Author: Jose Oliveira-Santos, Adroaldo Cesar Araujo Gaya, Anelise Reis Gaya, Carla Moreira, Pedro V. Silva, Caroline Brand, Jorge Mota, Luis Carlos Oliveira Lopes, César Agostinis-Sobrinho, Rute Santos, and Sandra Abreu
Subjects: Male, Gerontology, Adolescent, Physical activity, 030209 endocrinology & metabolism, Physical Therapy, Sports Therapy and Rehabilitation, Inflammation, Biology, Diet Surveys, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Orthopedics and Sports Medicine, Longitudinal Studies, Muscle, Skeletal, Exercise, Anthropometry, Portugal, 030229 sport sciences, General Medicine, Diet, C-Reactive Protein, Cross-Sectional Studies, Physical Fitness, Female, medicine.symptom
Abstract: High muscular fitness (MF) and high adherence to the Southern European Atlantic Diet (the SEADiet) have been associated with several positive metabolic outcomes. The purpose of the present study was two-fold: (i) to explore the independent associations between MF and C-reactive protein (CRP) levels; and (ii) to investigate the combined impact of MF and SEADiet on the CRP levels in a sample of adolescents. A cross-sectional school-based study was conducted on 463 adolescents (272 girls) aged 15-18 years, from the Portuguese Azorean Archipelago. Anthropometric indicators (stature, body mass, waist circumference (WC)) were measured by standardized protocols and pubertal stages were assessed by Tanner criteria. Blood samples were taken after an overnight fast. MF was assessed by the curl-up and push-up tests (from the Fitnessgram test battery). Adherence to the SEADiet was assessed with a semi-quantitative food frequency questionnaire. Linear regression models showed that MF was inversely associated with hs-CRP (unstandardized B = -0.127; p .009), after adjustments for age, sex, and pubertal stage, adherence of SEADiet, total energy intake and low-energy reporter and WC. Analysis of covariance (ANCOVA) showed a significant difference between the low adherence of SEADiet with low MF group and those with a high adherence of SEADiet and high MF (p .05) (F
Published: 2017

34. Risco metabólico em escolares está associado com baixos níveis de aptidão cardiorrespiratória, obesidade e perfil nutricional dos pais

Author: Elza Daniel de Mello, Miria Suzana Burgos, Cézane Priscila Reuter, Pâmela Ferreira Todendi, Anelise Reis Gaya, and Andréia Rosane de Moura Valim
Subjects: Blood Glucose, Male, Rural Population, School, Parents, Pediatrics, Urban Population, Cross-sectional study, Blood Pressure, 030204 cardiovascular system & hematology, Overweight, 0302 clinical medicine, Risk Factors, 030212 general & internal medicine, Child, Body mass index, Metabolic Syndrome, Índice de massa corporal, lcsh:RJ1-570, Lipoproteins, LDL, Obesidade, Escolares, Female, Underweight, medicine.symptom, Lipoproteins, HDL, Risk assessment, Brazil, Aptidão cardiorrespiratória, medicine.medical_specialty, Adolescent, Nutritional Status, 030209 endocrinology & metabolism, Risk Assessment, 03 medical and health sciences, Sex Factors, medicine, Humans, Pediatrics, Perinatology, and Child Health, Obesity, Cardiorespiratory fitness, Adolescentes, Triglycerides, Parental obesity, business.industry, lcsh:Pediatrics, medicine.disease, Cross-Sectional Studies, Pais, Sobrepeso, Pediatrics, Perinatology and Child Health, Exercise Test, business, Demography
Abstract: Objective: Verify the association between metabolic risk profile in students with different levels of cardiorespiratory fitness and body mass index, as well as the nutritional status of their parents. Methods: A cross-sectional study comprising 1.254 schoolchildren aged between seven and 17 years. The metabolic risk profile was calculated by summing the standardized values of high density lipoproteins and low density lipoproteins, triglycerides, glucose and systolic blood pressure. The parents’ nutritional status was evaluated by self-reported weight and height data, for body mass index calculating. The body mass index of schoolchildren was classified as underweight/normal weight and overweight/obesity. The cardiorespiratory fitness was assessed by 9-minute running/walk test, being categorized as fit (good levels) and unfit (low levels). Data were analyzed using prevalence ratio values (PR). Results: The data indicates a higher occurrence of developing metabolic risk in schoolchildren whose mother is obese (PR: 1.50; 95% CI: 1.01, 2.23), and even higher for those whose father and mother are obese (PR: 2, 79, 95% CI: 1.41; 5.51). Students who have low levels of cardiorespiratory fitness and overweight/obesity have higher occurrence of presenting metabolic risk profile (PR: 5.25; 95% CI: 3.31; 8.16). Conclusion: the occurrence of developing metabolic risk in schoolchildren increase when they have low levels of cardiorespiratory fitness and overweight/obesity, and the presence of parental obesity. Resumo: Objetivo: Verificar se há associação entre o perfil de risco metabólico em escolares com diferentes níveis de aptidão cardiorrespiratória e índice de massa corporal, bem como com o perfil nutricional de seus pais. Métodos: Estudo transversal constituído por 1.254 escolares com idade entre sete e 17 anos. O perfil de risco metabólico foi calculado por meio da soma dos valores estandardizados de lipoproteína de alta densidade e lipoproteína de baixa densidade, triglicerídeos, glicose e pressão arterial sistólica. O perfil nutricional dos pais foi avaliado pelos dados autorreferidos de peso e estatura, calculando-se posteriormente o índice de massa corporal. O índice de massa corporal do escolar foi classificado em baixo peso/peso normal e sobrepeso/obesidade. A aptidão cardiorrespiratória foi avaliada através do teste de corrida/caminhada de 9 minutos, sendo categorizada em apto (bons níveis) e inapto (baixos níveis). Os dados foram analisados através dos valores de razão de prevalência (RP). Resultados: Os dados apontam maior ocorrência de desenvolvimento de risco metabólico em escolares que apresentam mãe com obesidade (RP: 1,50; IC 95%: 1,01; 2,23) e, maior ainda, em escolares que possuem pai e mãe obesos (RP: 2,79; IC 95%: 1,41; 5,51). Escolares que apresentam baixos níveis de aptidão cardiorrespiratória e sobrepeso/obesidade possuem maior ocorrência de perfil metabólico de risco (RP: 5,25; IC 95%: 3,31; 8,16). Conclusões: a ocorrência de desenvolvimento de risco metabólico em escolares aumentam quando estes apresentam baixos níveis de aptidão cardiorrespiratória e sobrepeso/obesidade, assim como na presença de obesidade dos pais. Keywords: School, Cardiorespiratory fitness, Body mass index, Parents, Palavras-chave: Escolares, Aptidão cardiorrespiratória, Índice de massa corporal, Pais
Published: 2016

35. Distance from home to the nearest park and the use of the parks for physical activity: the mediator role of road safety perception in adolescents

Author: M.P. Maia Santos, Cíntia Fochesatto, Anelise Reis Gaya, Jorge Mota, Caroline Brand, Andreia Isabel Pizarro, Adroaldo Cezar Araujo Gaya, Arieli Fernandes Dias, and Thiago Monteiro Mendes
Subjects: Male, Mediation (statistics), Adolescent, Parks, Recreational, Poison control, Occupational safety and health, 03 medical and health sciences, Public space, Young Adult, 0302 clinical medicine, Residence Characteristics, Surveys and Questionnaires, Injury prevention, Humans, 030212 general & internal medicine, Socioeconomic status, Exercise, 030503 health policy & services, Public Health, Environmental and Occupational Health, Human factors and ergonomics, General Medicine, Cross-Sectional Studies, Walkability, Geographic Information Systems, Environment Design, Female, Perception, Safety, 0305 other medical science, Psychology, human activities, Brazil, Demography
Abstract: Objective The objective of the study is to examine whether adolescents' road safety perception (RSP) acts as a mediator on the association between the distance from home to the nearest park and the use of the parks for physical activity (PA). Study design This is a cross-sectional study. Methods The evaluation was through a random sample of 1130 adolescents (534 male), corresponding to 47.3%, 14–20 years old, from Porto Alegre, Brazil. RSP was assessed through some questions of the Neighborhood Environment Walkability Scale for Youth. Park use, socioeconomic status, age, and sex were measured using a questionnaire. Distance from home to the nearest park was evaluated through geographic information system. Data analysis was performed using Pearson correlation, and linear regression models were fitted as per the Baron and Kenny procedures for mediation analyses. All analyses were adjusted for sex and socioeconomic status. Results Road safety perception is independently associated with less distance from home to the nearest park (P = 0.04) and use of the parks for PA (P = 0.02). Road safety perception is a mediator and explains 16% of the association between park use and distance from home to the park (indirect Effect = −40.9966; 95% confidence interval [CI]: 119.3733–2.2455). Conclusion Our findings indicated that RSP is a mediator on the association between the distance from home to the nearest park and the use of the parks for PA. Future studies should take this into consideration frequency and intensity of PA and other environmental characteristics, such as crime, aesthetics, and neighborhood facilities.
Published: 2018

36. Obesity parameters as predictors of early development of cardiometabolic risk factors

Author: Andréia Rosane de Moura Valim, Lia Gonçalves Possuelo, Anelise Reis Gaya, Luciana Tornquist, Miria Suzana Burgos, Cézane Priscila Reuter, Jane Dagmar Pollo Renner, and Debora Tornquist
Subjects: Male, medicine.medical_specialty, Waist, Adolescent, Crianças, Cross-sectional study, Criança, Overweight, Standard score, Body Mass Index, chemistry.chemical_compound, Risk Factors, Internal medicine, medicine, Humans, Obesity, Child, Adolescentes, Adolescente, Fatores de risco, Cholesterol, business.industry, lcsh:Public aspects of medicine, Health Policy, Public Health, Environmental and Occupational Health, nutritional and metabolic diseases, lcsh:RA1-1270, medicine.disease, Cross-Sectional Studies, Blood pressure, Endocrinology, Risk factors, Obesidade, chemistry, Female, Waist Circumference, medicine.symptom, business, Body mass index, Brazil
Abstract: The scope of this study was to verify the association between different overweight and obesity parameters and the metabolic risk profile among school-age students. The randomized cross-sectional study included 1254 children and adolescents, aged 7 to 17, from a city in southern Brazil. Body mass index (BMI), waist circumference (WC) and percentage of fat (PF), measured at the triceps and based on subscapular skinfold thickness, were used as the parameters to evaluate overweight/obesity status. Systolic blood pressure (SBP), total cholesterol, high-density lipoprotein cholesterol (HDL), low-density protein cholesterol (LDL) and triglycerides were also measured. The metabolic risk profile was calculated based on the sum of the z score of the metabolic variables adjusted by age. A three-model Poisson analysis was used to verify the association between BMI, WC and PF with metabolic risk profile. BMI showed the highest probability for developing metabolic risk compared with WC (overweight - PR: 1.63 and obesity – PR: 3.87) and PF (overweight – PR: 1.62 and obesity – PR: 2.92). In conclusion, BMI seems to be a better parameter of overweight/obesity than WC and PF in the assessment of metabolic risk among youths. ResumoO objetivo deste estudo foi verificar associação entre diferentes parâmetros de sobrepeso e obesidade com o perfil de risco metabólico em escolares. O estudo transversal randomizado incluiu 1.254 crianças e adolescentes, com idades entre 7 e 17 anos, de uma cidade do sul do Brasil. O índice de massa corporal (IMC), a circunferência da cintura (CC) e o percentual de gordura (PG), avaliado através das medidas das dobras cutâneas tricipital e subescapular, foram usados como parâmetros para avaliar sobrepeso/obesidade. Pressão arterial sistólica (PAS), colesterol total, lipoproteína de alta densidade (HDL), lipoproteína de baixa densidade (LDL) e triglicerídeos também foram mensurados. O perfil de risco metabólico foi calculado com base no somatório do escore z das variáveis metabólicas ajustadas por idade. Três modelos de regressão de Poisson foram utlizados para verificar a associação entre IMC, CC e PG com o perfil de risco metabólico. Os dados demostram que o IMC foi o parâmetro que apresentou a maior associação com o desenvolvimento de risco metabólico, em comparação com CC (sobrepeso - RP: 1,63 e obesidade - RP: 3,87) e PG (sobrepeso - RP: 1,62 e obesidade - RP: 2,92). Conclui-se que o IMC parece ser um melhor parâmetro de sobrepeso/obesidade do que CC e PG, na avaliação do risco metabólico em escolares.
Published: 2015

37. Aggregation of risk indicators to cardiometabolic and musculoskeletal health in Brazilian adolescents in the periods 2008/09 and 2013/14

Author: Vanilson Batista Lemes, Anelise Reis Gaya, Priscila Antunes Marques, Arieli Fernandes Dias, Caroline Brand, Gabriela Guedes, Juliana Correa Gonçalves, and Adroaldo Cezar Araujo Gaya
Subjects: Gerontology, Male, Aptidão física, medicine.medical_specialty, Adolescent, Physical fitness, 030209 endocrinology & metabolism, Saúde, Logistic regression, Risk Assessment, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Metabolic Diseases, Environmental health, Systematic risk, Epidemiology, Medicine, Musculoskeletal health, Humans, Obesity, 030212 general & internal medicine, Musculoskeletal Diseases, Child, Descriptive statistics, business.industry, lcsh:RJ1-570, Cardiorespiratory fitness, lcsh:Pediatrics, 030229 sport sciences, Obesidade, Cardiorespiratory Fitness, Health, Cardiovascular Diseases, Pediatrics, Perinatology and Child Health, Exercise Test, Female, business, Body mass index, Brazil
Abstract: Objective: To assess the occurrence of an aggregate risk to cardiometabolic and musculoskeletal health of Brazilian adolescents in the period 2008/09 and 2013/14 and to identify whether there are differences in risk between the genders and in these periods. Methods: This was a trend epidemiological study with a quantitative approach, consisting of a voluntary sample of adolescents from 16 Brazilian states. Data were extracted from the database of Brazil Sports Project (Projeto Esporte Brasil). Health-related physical fitness was evaluated based on body mass index, cardiorespiratory fitness, flexibility, and abdominal strength/resistance. Descriptive analysis, chi-squared test, and Poisson log regression were used for the statistical treatment. Results: In the years 2008/09, 14.6% of Brazilian youngsters showed an aggregate risk to cardiometabolic health and 17.1% an aggregate risk for musculoskeletal indicators, whereas in 2013/14, the values of the risk indicators were, respectively 40.0% and 22.4%. It was observed that, in the years 2013/14, the risk to the cardiometabolic health of boys was 2.51 times greater than in 2008/09, while for girls, a three-fold increase in risk was observed. Concerning musculoskeletal health, girls showed a 2.21 risk of being in the risk zone in 2013/14 when compared with 2008/09. Conclusion: The occurrence of an aggregate risk to the cardiometabolic and musculoskeletal health of Brazilian adolescents increased in the 2008/09 and 2013/14 periods. Regarding gender, an increase in the cardiometabolic and musculoskeletal risk between these periods was observed in girls. As for boys, an increase was observed only in cardiometabolic risk. Resumo: Objetivo: Verificar a ocorrência de risco agregado à saúde cardiometabólica e musculoesquelética de adolescentes brasileiros no período de 2008/09 e 2013/14 e identificar se existem diferenças no risco entre os sexos e nesses períodos. Métodos: Trata-se de um estudo epidemiológico de tendência com abordagem quantitativa, composto por uma amostra voluntária de adolescentes, de 16 estados brasileiros. Os dados foram extraídos da base de dados do Projeto Esporte Brasil. A aptidão física relacionada a saúde foi avaliada a partir de: índice de massa corporal, aptidão cardiorrespiratória, flexibilidade, e força/resistência abdominal. Para o tratamento estatístico foi utilizado análise descritiva, qui-quadrado e regressão Poisson log. Resultados: Nos anos de 2008/09, 14,6% de jovens brasileiros apresentaram risco à saúde cardiometabólica agregada e 17,1% risco agregado dos indicadores musculoesqueléticos. Enquanto em 2013/14, os valores dos indicadores de risco foram, respectivamente 40,0% e 22,4%. Observou-se que nos anos de 2013/14 o risco à saúde cardiometabólica dos meninos era 2,51 vezes maior que em 2008/09. Já para as meninas o aumento desse risco foi de 3 vezes. No que se refere à saúde musculoesquelética, as meninas apresentaram risco de 2,21 de estar na zona de risco em 2013/14 em relação à 2008/09. Conclusão: A ocorrência de risco agregado à saúde cardiometabólica e musculoesquelética de adolescentes brasileiros aumentou no período de 2008/09 e 2013/14. Com relação ao sexo houve um aumento no risco cardiometabólico e musculoesquelético nas meninas entre esses períodos. Já para os meninos houve aumento apenas do risco cardiometabólico. Keywords: Health, Physical fitness, Obesity, Palavras-chave: Saúde, Aptidão física, Obesidade
Published: 2016

38. A 3-Year Longitudinal Analysis of Changes in Body Mass Index

Author: Maria Paula Santos, Denisa Mendonça, Luísa Aires, Jorge Mota, Gustavo Silva, José Carlos Ribeiro, and Anelise Reis Gaya
Subjects: Male, Gerontology, Longitudinal study, Adolescent, Physical fitness, Physical Therapy, Sports Therapy and Rehabilitation, Motor Activity, Overweight, Body Mass Index, Screen time, medicine, Humans, Orthopedics and Sports Medicine, Longitudinal Studies, Obesity, Child, Computers, business.industry, Cardiorespiratory fitness, medicine.disease, El Niño, Physical Fitness, Female, Television, Waist Circumference, medicine.symptom, business, Body mass index
Abstract: The aim of this study was to analyse whether Physical Activity Index (PAI), Physical Fitness, Screen Time (watching TV and computer use), Socio-economic Status and Commuting to School made a significant contribution to longitudinal changes in Body Mass Index (BMI) in youth. This longitudinal study was carried out over a period of 3 years with 345 students (147 boys) who were between 11 and 16 years old at the beginning of the study. Students were invited to perform tests from FITNESSGRAM Battery for Curl-Ups, Push-Ups, Back-Saver Sit and Reach, and 20 m Shuttle-Run (CRF). Fitness tests were categorized in "Healthy Zone" (HZ) and "Under Healthy Zone" (UHZ), PAI in "less active" and "active"; Socio-economic Status, in low, middle and high education level, and Commuting in active and passive. BMI was corrected for age and gender meaning that we subtracted the age-and-sex-specific cut points for overweight. Corrected body mass index was used as dependent variable in a Linear Mixed Model. The main result was the strong positive and independent association of individuals with CRF performances UHZ with corrected body mass index. In conclusion, the results of this longitudinal study showed markedly an important relationship of lower fitness levels with the risk of being overweight/obese, in particular CRF and abdominal strength.
Published: 2009

39. Association between time spent in sedentary, moderate to vigorous physical activity, body mass index, cardiorespiratory fitness and blood pressure

Author: Clarice Martins, Alberto Jorge Alves, José Carlos Ribeiro, Jorge Mota, Luísa Aires, and Anelise Reis Gaya
Subjects: Male, Aging, medicine.medical_specialty, Time Factors, Adolescent, Physiology, Epidemiology, Rest, Physical fitness, Blood Pressure, Body Mass Index, Internal medicine, Genetics, medicine, Humans, Exercise physiology, Child, Exercise, Sex Characteristics, Anthropometry, business.industry, Public Health, Environmental and Occupational Health, Cardiorespiratory fitness, Body Height, Intensity (physics), Blood pressure, Physical Fitness, Cardiology, Physical therapy, Regression Analysis, Female, business, Body mass index, Sex characteristics
Abstract: Elevated blood pressure (BP) has been reported in young people and seems to be associated with body mass index (BMI) and reduced physical activity (PA).This study sought to analyse the association of BP with BMI, PA intensity patterns and cardiorespiratory fitness (CRF) in youth.A cross-sectional study was carried out including 66 boys (13.91+/-1.76) and 97 girls (14.02+/-1.71). Anthropometric characteristics, CRF and BP were assessed during school time and accelerometers were utilized to determine intensity of PA.The linear regression model, adjusted for age, sex and height, showed that higher values of BMI were associated (por=0.05) with higher values of systolic blood pressure (SBP) (1.39; 95% CI: 0.56; 2.23) and diastolic blood pressure (DBP) (1.52; 95% CI: 0.68; 2.37). Additionally, SBP, but not DBP, was inversely associated (por=0.05) with moderate PA (-0.25; 95% CI: -0.47; -0.02) and positively correlated with sedentary activities (0.04; 95% CI: 0.00; 0.08).The present study showed that BMI and time spent in sedentary activities were inversely associated with SBP. However, time spent in moderate PA was positively associated with SBP. BMI was the single predictor of DBP.
Published: 2009

40. Skeletal Muscle Pathways of Contraction-Enhanced Glucose Uptake

Author: S. B. Ribeiro, Anelise Reis Gaya, Julia M. Santos, José Alberto Duarte, and Hans-Joachim Appell
Subjects: medicine.medical_specialty, Contraction (grammar), Sarcolemma, biology, Insulin, medicine.medical_treatment, Glucose uptake, Glucose transporter, Skeletal muscle, Physical Therapy, Sports Therapy and Rehabilitation, Glucose, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 2, Internal medicine, biology.protein, medicine, Humans, Orthopedics and Sports Medicine, medicine.symptom, Muscle, Skeletal, GLUT4, Muscle Contraction, Muscle contraction
Abstract: Muscle contraction acutely increases glucose transport in both healthy and type 2 diabetic individuals. Since glucose uptake during muscle contraction has been observed in the absence of insulin, the existence of an insulin-independent pathway has been suggested to explain this phenomenon. However, the exact mechanism behind the translocation of GLUT4 vesicles through the sarcolemma during muscle contraction is still unknown. Some substances, such as AMPK and calcium activated proteins, have been suggested as potential mediators but the exact mechanisms of their involvement remain to be elucidated. A hypothetical convergence point between the insulin cascade and the potential pathways triggered by muscle contraction has been suggested. Therefore, the earliest concept that two different routes exist in skeletal muscle has been progressively modified to the notion that glucose uptake is induced by muscle contraction via components of the insulin pathway. With further consideration, increased glucose uptake and enhanced insulin sensitivity observed during/after exercise might be explained by a metabolic- and calcium-dependent activation of several intermediate molecules of the insulin cascade. This paper aimed to review the literature in order to examine in detail these concepts behind muscle contraction-induced glucose uptake.
Published: 2008

41. FTO polymorphism, cardiorespiratory fitness, and obesity in Brazilian youth

Author: Cézane Priscila, Reuter, Andréia, Rosane De Moura Valim, Anelise Reis, Gaya, Tássia Silvana, Borges, Elisa Inês, Klinger, Lia Gonçalves, Possuelo, Silvia Isabel Rech, Franke, Lívia, Kmetzsch, Marilene Henning, Vainstein, Daniel, Prá, and Miria Suzana, Burgos
Subjects: Male, Pediatric Obesity, Polymorphism, Genetic, Adolescent, Cardiorespiratory Fitness, Prevalence, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Humans, Female, Child, Brazil
Abstract: The aim of the present study was to evaluate the relationship between the rs9939609 fat mass and obesity-associated (FTO) polymorphism and cardiorespiratory fitness (CRF) with overweight/obesity outcomes in youth.This study included 420 youths, comprising 211 boys and 209 girls aged 7-17. Overweight/obesity were evaluated by body mass index (BMI), waist circumference (WC), and the percentage of fat (PF) according to two skinfold thickness measurements. Genotyping of the rs9939609 polymorphism was conducted using real-time Polymerase Chain Reaction (PCR) utilizing TaqMan(®) probes, and CRF was evaluated through a 9-minute run/walk test, categorized as fit or unfit. Logistic regression was utilized to evaluate a possible association between the polymorphism and CRF, with three obesity indicators evaluated.Individuals with the genotype risk (AA) of FTO polymorphism rs9939609 showed higher prevalence of overweight/obesity, as evaluated by BMI (OR: 3.21; CI: 1.71-6.05), WC (OR: 2.59; CI: 1.35-4.97), and PF (OR: 2.59; CI: 1.36-4.92). Additionally, students with the AA genotype in the unfit model had a significant odds ratio for obesity (OR: 4.40; CI: 1.83-10.61 for BMI; OR: 3.54; CI: 1.58-7.96 for WC), whereas we did not observe associations between the AA genotype with BMI and WC using the fit model. Conversely, PF was associated with the AA genotype only in the fit model (OR: 3.24; CI: 1.26-8.34).This study demonstrated that the rs9939609 (FTO) polymorphism showed a relationship with obesity in the population studied and an interaction with CRF. Students with low levels of CRF and the AA genotype have a higher risk of being overweight/obese. This association was not found in students with higher levels of CRF. Am. J. Hum. Biol. 28:381-386, 2016. © 2015 Wiley Periodicals, Inc.
Published: 2015

42. Time course of low- and high-volume strength training on neuromuscular adaptations and muscle quality in older women

Author: Eurico Nestor Wilhelm, Amanda Peruzzolo, Ronei Silveira Pinto, Lee E. Brown, Régis Radaelli, Fabiano Cézar Lacerda, Cíntia Ehlers Botton, Anelise Reis Gaya, Martim Bottaro, and Kelly Moraes
Subjects: medicine.medical_specialty, Aging, Time Factors, Strength training, Isometric exercise, Electromyography, Article, Lower body, Physical medicine and rehabilitation, One-repetition maximum, Isometric Contraction, medicine, Humans, Muscle Strength, Muscle, Skeletal, Aged, Ultrasonography, medicine.diagnostic_test, business.industry, Upper body, Resistance Training, General Medicine, Middle Aged, Adaptation, Physiological, Healthy Volunteers, Time course, Body Composition, Physical Endurance, Female, Geriatrics and Gerontology, business, Follow-Up Studies
Abstract: This study investigated the effects of low- and high-volume strength trainings on neuromuscular adaptations of lower- and upper-body muscles in older women after 6 weeks (6WE), 13 weeks (13WE), and 20 weeks (20WE) of training. Healthy older women were assigned to low-volume (LV) or high-volume (HV) training groups. The LV group performed one set of each exercise, while the HV group performed three sets, 2 days/week. Knee extension and elbow flexion one-repetition maximum (1-RM), maximal isometric strength, maximal muscle activation, and muscle thickness (MT) of the lower- and upper-body muscles, as well as lower-body muscle quality (MQ) obtained by ultrasonography, were evaluated. Knee extension and elbow flexion 1-RM improved at all time points for both groups; however, knee extension 1-RM gains were greater for the HV group after 20WE. Maximal isometric strength of the lower body for both groups increased only at 20WE, while upper-body maximal isometric strength increased after 13WE and 20WE. Maximal activation of the lower and upper body for both groups increased only after 20WE. Both groups showed significant increases in MT of their lower and upper body, with greater gains in lower-body MT for the HV group at 20WE. MQ improved in both groups after 13WE and 20WE, whereas the HV group improved more than the LV group at 20WE. These results showed that low- and high-volume trainings have a similar adaptation time course in the muscular function of upper-body muscles. However, high-volume training appears to be more efficient for lower-body muscles after 20 weeks of training.
Published: 2013

43. Low- and high-volume strength training induces similar neuromuscular improvements in muscle quality in elderly women

Author: Cíntia Ehlers Botton, Eurico Nestor Wilhelm, Kelly Moraes, Fabiano Cézar Lacerda, Anelise Reis Gaya, Amanda Peruzzolo, Martim Bottaro, Lee E. Brown, Régis Radaelli, and Ronei Silveira Pinto
Subjects: medicine.medical_specialty, Aging, Knee Joint, Vastus medialis, Strength training, Physical Exertion, Isometric exercise, Electromyography, Muscle mass, Biochemistry, Biceps, Muscle hypertrophy, Endocrinology, Internal medicine, Elbow Joint, Genetics, medicine, Humans, Muscle Strength, Range of Motion, Articular, Muscle, Skeletal, Molecular Biology, Aged, Ultrasonography, medicine.diagnostic_test, business.industry, Resistance Training, Cell Biology, Middle Aged, Adaptation, Physiological, Cardiology, Physical therapy, Female, business, Echo intensity
Abstract: The aim of this study was to compare the effects of low- and high-volume strength training on strength, muscle activation and muscle thickness (MT) of the lower- and upper-body, and on muscle quality (MQ) of the lower-body in older women. Twenty apparently healthy elderly women were randomly assigned into two groups: low-volume (LV, n=11) and high-volume (HV, n=9). The LV group performed one-set of each exercise, while the HV group performed three-sets of each exercise, twice weekly for 13 weeks. MQ was measured by echo intensity obtained by ultrasonography (MQEI), strength per unit of muscle mass (MQST), and strength per unit of muscle mass adjusted with an allometric scale (MQAS). Following training, there was a significant increase (p≤0.001) in knee extension 1-RM (31.8±20.5% for LV and 38.3±7.3% for HV) and in elbow flexion 1-RM (25.1±9.5% for LV and 26.6±8.9% for HV) and in isometric maximal strength of the lower-body (p≤0.05) and upper-body (p≤0.001), with no difference between groups. The maximal electromyographic activation for both groups increased significantly (p≤0.05) in the vastus medialis and biceps brachii, with no difference between groups. All MT measurements of the lower- and upper-body increased similarly in both groups (p≤0.001). Similar improvements were also observed in MQEI (p≤0.01), MQST, and MQAS (p≤0.001) for both groups. These results demonstrate that low- and high-volume strength training promote similar increases in neuromuscular adaptations of the lower- and upper-body, and in MQ of the lower-body in elderly women.
Published: 2013

44. Cardiorespiratory fitness and TV viewing in relation to metabolic risk factors in Portuguese adolescents

Author: Clarice Martins, Anelise Reis Gaya, José Carlos Ribeiro, Susana Vale, Rute Santos, Carla Moreira, Maria Paula Santos, and Jorge Mota
Subjects: Male, Aging, Waist, Adolescent, Physiology, Epidemiology, Motor Activity, Logistic regression, Body Mass Index, Risk Factors, Genetics, Medicine, Humans, Tv viewing, Child, Metabolic Syndrome, Portugal, business.industry, Metabolic risk, Public Health, Environmental and Occupational Health, Cardiorespiratory fitness, Circumference, language.human_language, Cross-Sectional Studies, Logistic Models, Physical Fitness, language, Body Composition, Female, Television, Portuguese, Waist Circumference, business, Social psychology, Body mass index, Demography
Abstract: The purpose of this study was to examine whether adolescents who have high levels of cardiorespiratory fitness (CRF) co-existing with low levels of television (TV) viewing present a better metabolic risk profile compared to their low fit and high TV viewing counterparts.A total of 372 students (aged 12-15 years old) comprised the sample of this study. Anthropometric data (body mass index and waist circumference) was collected. CRF was calculated based upon the 20 metres shuttle run test. A questionnaire was used to estimate weekly TV viewing. Information about biological maturity and parental education was collected. Participants were then categorized into one of four category profiles according to the scores they achieved: low TV-Fit; high TV-Fit; low TV-Unfit and high TV-Unfit. Metabolic risk score (MRS) was calculated based on the sum of the Z-scores of all the metabolic variables analysed.Logistic regression analyses indicated that the high TV-Unfit group was almost 3-times more likely to be assigned to the high MRS group (OR = 2.85, 95% CI = 1.08-7.50) compared to their low TV-Fit group counterparts.The data showed that the high TV-Unfit group was associated with an increased metabolic risk in adolescents after adjustment for gender, age, biological maturity and parental education.
Published: 2013

45. 3 Different types of strength training in older women

Author: Dain P. LaRoche, Eurico Nestor Wilhelm, Fabiano Cézar Lacerda, Ronei Silveira Pinto, Anelise Reis Gaya, Régis Radaelli, Cleiton Silva Correa, Martim Bottaro, Marcus Peikriszwili Tartaruga, Eduardo Lusa Cadore, Alvaro Reischak-Oliveira, and Luiz Fernando Martins Kruel
Subjects: medicine.medical_specialty, Knee extensors, Vastus medialis, business.industry, Strength training, Physical Therapy, Sports Therapy and Rehabilitation, Muscle activation, Resistance Training, Knee extension, Concentric, Middle Aged, law.invention, Specific strength, Randomized controlled trial, law, Anesthesia, Physical therapy, Medicine, Humans, Orthopedics and Sports Medicine, Female, Muscle Strength, business, Muscle, Skeletal, Aged
Abstract: The objective of the present study was to evaluate and compare the neuromuscular, morphological and functional adaptations of older women subjected to 3 different types of strength training. 58, healthy women (67 ± 5 year) were randomized to experimental (EG, n=41) and control groups (CG, n=17) during the first 6 weeks when the EG group performed traditional resistance exercise for the lower extremity. Afterwards, EG was divided into three specific strength training groups; a traditional group (TG, n=14), a power group (PG, n=13) that performed the concentric phase of contraction at high speed and a rapid strength group (RG, n=14) that performed a lateral box jump exercise emphasizing the stretch-shortening-cycle (SSC). Subjects trained 2 days per week through the entire 12 weeks. Following 6 weeks of generalized strength training, significant improvements occurred in EG for knee extension one-repetition (1RM) maximum strength (+19%), knee extensor muscle thickness (MT, +15%), maximal muscle activation (+44% average) and onset latency ( -31% average) for vastus lateralis (VL), vastus medialis (VM) and rectus femoris (RF) compared to CG (p0.05). Following 6 more weeks of specific strength training, the 1RM increased significantly and similarly between groups (average of +21%), as did muscle thickness of the VL (+25%), and activation of VL (+44%) and VM (+26%). The onset latency of RF (TG=285 ± 109 ms, PG=252 ± 76 ms, RG=203 ± 43 ms), reaction time (TG=366 ± 99 ms, PG=274 ± 76 ms, RG=201 ± 41 ms), 30-s chair stand (TG=18 ± 3, PG=18 ± 1, RG=21 ± 2) and counter movement jump (TG=8 ± 2 cm, PG=10 ± 3 cm, RG=13 ± 2 cm) was significantly improved only in RG (p0.05). At the end of training, the rate of force development (RFD) over 150 ms (TG=2.3 ± 9.8 N·s(-1), PG=3.3 ± 3.2 N·s(-1), RG=3.8 ± 6.8 N·s(-1), CG=2.3 ± 7.0 N·s(-1)) was significantly greater in RG and PG than in TG and CG (p0.05). In conclusion, rapid strength training is more effective for the development of rapid force production of muscle than other specific types of strength training and by consequence, better develops the functional capabilities of older women.
Published: 2012

46. Cardiorespiratory fitness predicts later body mass index, but not other cardiovascular risk factors from childhood to adolescence

Author: Jorge Mota, Anelise Reis Gaya, Clarisse Martins, Jos W. R. Twisk, Rute Santos, José Carlos Ribeiro, Epidemiology and Data Science, EMGO - Lifestyle, overweight and diabetes, Methodology and Applied Biostatistics, and EMGO+ - Lifestyle, Overweight and Diabetes
Subjects: Male, Pediatrics, medicine.medical_specialty, Adolescent, Cardiovascular risk factors, Body Mass Index, Age and gender, Oxygen Consumption, Predictive Value of Tests, Risk Factors, Genetics, Hum, Medicine, Humans, Longitudinal Studies, Child, Ecology, Evolution, Behavior and Systematics, Portugal, business.industry, Multilevel model, Cardiorespiratory fitness, Cardiovascular Diseases, Physical Fitness, Anthropology, Multivariate Analysis, Female, Anatomy, business, Body mass index
Abstract: We analyzed the 5-year longitudinal relationship between cardiorespiratory fitness (CRF) and cardiovascular diseases (CVD) risk factors in children. A total of 153 students (66 boys and 87 girls) were evaluated in 1998 and 2003. Multilevel modeling was used to determine the effect of CRF across time (Model 1, adjusted for time and Model 2—Model 1 with further adjustment for gender and age). In both models, a significant main effect was found for body mass index (BMI) (P ≤ 0.05). Data showed that in children, lower levels of CRF are associated with higher levels of BMI over a 5-year follow-up period. Am. J. Hum. Biol., 2009. © 2008 Wiley-Liss, Inc.
Published: 2008

47. Trends of underweight, overweight, and obesity in Brazilian children and adolescents

Author: Ricardo Demetrio de Souza Petersen, Adroaldo Cezar Araujo Gaya, Anelise Reis Gaya, and Larissa Sabbado Flores
Subjects: Male, Gerontology, Longitudinal study, Time Factors, Children and adolescents, Adolescent, Crianças, Nutritional Status, Overweight, Desnutrição, BMI, IMC, Thinness, Educação física, Prevalence, Humans, Medicine, Longitudinal Studies, Pediatrics, Perinatology, and Child Health, Obesity, Child, Adolescentes, Crianças e adolescentes, Body mass index, Multinomial logistic regression, Índice de massa corporal, High prevalence, business.industry, Malnutrition, lcsh:RJ1-570, adolescentes, lcsh:Pediatrics, medicine.disease, Trend analysis, Obesidade, Sobrepeso, Pediatrics, Perinatology and Child Health, Female, medicine.symptom, Underweight, business, Brazil, Forecasting, Demography
Abstract: Objective: To describe and analyze the trends of occurrence of underweight, overweight, and obesity in schoolchildren. Methods: This was a longitudinal study of trends conducted in a voluntary sample of Brazilian children and adolescents. The sample was grouped by year of collection (period I: 2005 and 2006; period II: 2007 and 2008, and period III: 2009-2011), age category (children: 7 to 10 years, and adolescents: 11 to 14 years), and stratified by gender. The body mass index was used to classify the nutritional profile. Trend analysis was verified using multinomial logistic regression (p
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