1. Detection rate of clinically significant prostate cancer in magnetic resonance imaging and ultrasonography‐fusion transperineal targeted biopsy for lesions with a prostate imaging reporting and data system version 2 score of 3–5
- Author
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Haruki Kume, Tomoko Masuda, Yuji Hakozaki, Hisashi Matsushima, Nobuo Kawauchi, Yoko Hirai, Munehiro Yokoyama, Taro Murata, and Mai Oda
- Subjects
Image-Guided Biopsy ,Male ,medicine.medical_specialty ,Prostate biopsy ,Urology ,030232 urology & nephrology ,clinically significant prostate cancer ,Magnetic Resonance Imaging, Interventional ,Original Articles: Clinical Investigation ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Japan ,Prostate ,Biopsy ,Image Processing, Computer-Assisted ,Humans ,Medicine ,prostate biopsy ,Original Article: Clinical Investigation ,Ultrasonography, Interventional ,Multiparametric Magnetic Resonance Imaging ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Ultrasound ,Prostatic Neoplasms ,Cancer ,Magnetic resonance imaging ,Middle Aged ,multiparametric magnetic resonance imaging ,medicine.disease ,prostate imaging reporting and data system version 2 ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Biopsy, Large-Core Needle ,magnetic resonance imaging/ultrasound fusion biopsy ,Radiology ,business - Abstract
Objectives To evaluate the detection rates of clinically significant prostate cancer classified according to the prostate imaging reporting and data system scoring system using magnetic resonance imaging/ultrasound rigid fusion targeted biopsy. Methods A total of 339 patients underwent transperineal magnetic resonance imaging/ultrasound rigid fusion targeted biopsy in our institution between January 2015 and July 2017. Patients with prostate imaging reporting and data system category 1 or 2 and those with a pre‐biopsy prostate‐specific antigen value of >30 ng/mL were excluded from this study. Finally, 310 patients were recruited. Results The detection rates of clinically significant prostate cancer with prostate imaging reporting and data system category 3, 4, and 5 were 1.0% (1/98), 35.1% (47/134) and 73.1% (57/78), respectively. The factors affecting the detection of clinically significant prostate cancer with prostate imaging reporting and data system categories 4 and 5 were: (i) prostate imaging reporting and data system category 5; (ii) prostate volume 0.35 ng/mL/mL. Conclusions The detection rate of clinically significant prostate cancer on magnetic resonance imaging/ultrasound rigid fusion targeted biopsy is very low in patients with prostate imaging reporting and data system category 3; therefore, patients with this classification should not undergo targeted biopsy. Prostate‐specific antigen density, prostate volume, locations of suspected cancer and history of biopsy should be considered to predict the detection rate of clinically significant prostate cancer with prostate imaging reporting and data system categories 4 and 5.
- Published
- 2018