1. Autochthonous Crimean-Congo Hemorrhagic Fever in Spain
- Author
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Anabel, Negredo, Fernando, de la Calle-Prieto, Eduardo, Palencia-Herrejón, Marta, Mora-Rillo, Jenaro, Astray-Mochales, María P, Sánchez-Seco, Esther, Bermejo Lopez, Javier, Menárguez, Ana, Fernández-Cruz, Beatriz, Sánchez-Artola, Elena, Keough-Delgado, Eva, Ramírez de Arellano, Fátima, Lasala, Jakob, Milla, Jose L, Fraile, Maria, Ordobás Gavín, Amalia, Martinez de la Gándara, Lorenzo, López Perez, Domingo, Diaz-Diaz, M Aurora, López-García, Pilar, Delgado-Jimenez, Alejandro, Martín-Quirós, Elena, Trigo, Juan C, Figueira, Jesús, Manzanares, Elena, Rodriguez-Baena, Luis, Garcia-Comas, Olaia, Rodríguez-Fraga, Nicolás, García-Arenzana, Maria V, Fernández-Díaz, Victor M, Cornejo, Petra, Emmerich, Jonas, Schmidt-Chanasit, Jose R, Arribas, Fernando, Cava, European Union, and Red de Investigación Cooperativa en Enfermedades Tropicales (España)
- Subjects
0301 basic medicine ,Crimean–Congo hemorrhagic fever ,Male ,Infectious Disease Transmission, Patient-to-Professional ,Colon ,Tick ,Polymerase Chain Reaction ,Virus ,03 medical and health sciences ,Necrosis ,Fatal Outcome ,parasitic diseases ,medicine ,media_common.cataloged_instance ,Humans ,Viral rna ,European union ,media_common ,biology ,business.industry ,Infectious disease transmission ,General Medicine ,Middle Aged ,biology.organism_classification ,medicine.disease ,Virology ,030104 developmental biology ,Liver ,Spain ,Hemorrhagic Fever Virus, Crimean-Congo ,Female ,Hemorrhagic Fever, Crimean ,Contact Tracing ,business ,Liver pathology ,Multiplex Polymerase Chain Reaction ,Contact tracing - Abstract
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed, viral, tickborne disease. In Europe, cases have been reported only in the southeastern part of the continent. We report two autochthonous cases in Spain. The index patient acquired the disease through a tick bite in the province of Ávila - 300 km away from the province of Cáceres, where viral RNA from ticks was amplified in 2010. The second patient was a nurse who became infected while caring for the index patient. Both were infected with the African 3 lineage of this virus. (Funded by Red de Investigación Cooperativa en Enfermedades Tropicales [RICET] and Efficient Response to Highly Dangerous and Emerging Pathogens at EU [European Union] Level [EMERGE].). Supported by Red de Investigación Cooperativa en Enferme-dades Tropicales (RICET grant, RD12/0018/0023) and EMERGE (Efficient Response to Highly Dangerous and Emerging Patho-gens at EU [European Union] Level), a joint action funded under the third EU Health Program (677066),.Disclosure forms provided by the authors are available with the full text of this article at NEJM.org.We thank Julio Farias of the Pathology Department at Gregorio Marañón University General Hospital and Maria José Buitrago and the rest of the members of the Grupo de Respuesta Rápida of the Centro Nacional de Microbiología for their help. Sí
- Published
- 2017