1. Phrenic nerve conduction in the early stage of Guillain?Barre syndrome might predict the respiratory failure
- Author
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H. Ito, K. Fujita, Y. Kinoshita, Y. Takanashi, and H. Kusaka
- Subjects
Adult ,Male ,Neural Conduction ,Diaphragmatic breathing ,Guillain-Barre Syndrome ,Cohort Studies ,Predictive Value of Tests ,Reaction Time ,medicine ,Humans ,Respiratory system ,Child ,Aged ,Phrenic nerve ,Guillain-Barre syndrome ,business.industry ,Respiratory disease ,General Medicine ,Middle Aged ,medicine.disease ,Respiration, Artificial ,Compound muscle action potential ,Phrenic Nerve ,Electrophysiology ,Neurology ,Respiratory failure ,Anesthesia ,Female ,Neurology (clinical) ,Respiratory Insufficiency ,business ,Needs Assessment - Abstract
Objective – To investigate whether phrenic nerve conduction in the early phase of Guillain– Barre syndrome (GBS) predicts the need for respiratory assistance during the subsequent clinical course. Material and methods – We performed electrophysiological examinations of conventional peripheral nerve conduction and phrenic nerve conduction for GBS patients within 14 days from the onset. We excluded patients who had already been treated with immuno-related therapy and respiratory assistance. Results – Fifteen patients were enrolled. Three patients with the sum of phrenic nerve latency longer than 30 ms and the sum of bilateral diaphragmatic compound muscle action potential amplitude smaller than 0.3 mV required respiratory assistance after the conduction test. Conclusion – Our findings showed that not only delayed distal latency but also decreased amplitude may predict the need for respiratory assistance during the subsequent disease course.
- Published
- 2007