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4 results on '"Farida Lamkarkach"'

1. The joint effect of asbestos exposure, tobacco smoking and alcohol drinking on laryngeal cancer risk: evidence from the French population-based case-control study, ICARE

Author

Gwenn, Menvielle, Aurore, Fayossé, Loredana, Radoï, Florence, Guida, Marie, Sanchez, Matthieu, Carton, Diane, Cyr, Annie, Schmaus, Sylvie, Cénée, Joëlle, Fevotte, Patricia, Delafosse, Isabelle, Stücker, Danièle, Luce, Farida, Lamkarkach, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Centre de recherche en épidémiologie et santé des populations (CESP), Hôpital Paul Brousse-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Oral medicine and oral surgery department, Université Paris Descartes - Paris 5 (UPD5), UMS 011, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Epidémiologie environnementale des cancers, Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement (UMRESTTE UMR T9405), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR), FRANCIM, Réseau des registres français du cancer, Institut Pierre Louis d'Epidémiologie et de Santé Publique ( iPLESP ), Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Université Pierre et Marie Curie - Paris 6 ( UPMC ), Institut de recherche, santé, environnement et travail ( Irset ), Université d'Angers ( UA ) -Université de Rennes 1 ( UR1 ), Université de Rennes ( UNIV-RENNES ) -Université de Rennes ( UNIV-RENNES ) -École des Hautes Études en Santé Publique [EHESP] ( EHESP ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) -Université des Antilles ( UA ), Centre de recherche en épidémiologie et santé des populations ( CESP ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Université Paris-Sud - Paris 11 ( UP11 ) -Assistance publique - Hôpitaux de Paris (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Université Paris Descartes - Paris 5 ( UPD5 ), Université de Versailles Saint-Quentin-en-Yvelines ( UVSQ ) -Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud - Paris 11 ( UP11 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement ( UMRESTTE UMR T9405 ), Université Claude Bernard Lyon 1 ( UCBL ), Université de Lyon-Université de Lyon-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux ( IFSTTAR ), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Pierre et Marie Curie - Paris 6 (UPMC), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Cohortes épidémiologiques en population (CONSTANCES), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université de Paris (UP), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), and Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité)

Subjects
Male, Alcohol Drinking, [SDV]Life Sciences [q-bio], Health Behavior, Alcohol, medicine.disease_cause, Asbestos, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Environmental health, Occupational Exposure, Tobacco, Odds Ratio, Medicine, Humans, Laryngeal Neoplasms, [ SDV ] Life Sciences [q-bio], Ethanol, business.industry, Smoking, Public Health, Environmental and Occupational Health, Absolute risk reduction, Case-control study, Cancer, Odds ratio, Middle Aged, medicine.disease, 030210 environmental & occupational health, 3. Good health, Occupational Diseases, Alcoholism, chemistry, 030220 oncology & carcinogenesis, Case-Control Studies, Occupational exposure, France, business, Cancer risk
Abstract

International audience; Objective The objective of the study was to investigate the joint effect of occupational exposure to asbestos, and tobacco and alcohol consumption, on the risk of laryngeal cancer among men. Methods We used data from a large population-based case–control study conducted in France. We estimated two-way and three-way interactions between asbestos exposure (never vs ever exposed), tobacco consumption (\textless20 vs ≥20 pack-years) and alcohol consumption (\textless5 vs ≥5 drinks per day). The interaction on an additive scale was assessed by estimating the relative excess risk due to interaction (RERI) and the attributable proportion due to interaction, and the interaction on a multiplicative scale was assessed by estimating the multiplicative interaction parameter (ψ). Multiplicative interactions were also assessed using fractional polynomials for alcohol drinking, tobacco smoking and asbestos exposure. Results When compared with light-to-moderate smokers and drinkers never exposed to asbestos, the increase in laryngeal cancer risk was smallest among light-to-moderate drinkers and smokers exposed to asbestos (OR=2.23 (1.08 to 4.60)), and highest among heavy smokers and drinkers ever exposed to asbestos (OR=69.39 (35.54 to 135.5)). We found an additive joint effect between asbestos exposure and alcohol consumption (RERI=4.75 (−4.29 to 11.12)), whereas we observed a more than additive joint effect between asbestos exposure and tobacco consumption (RERI=8.50 (0.71 to 23.81)), as well as between asbestos exposure, and tobacco and alcohol consumption (RERI=26.57 (11.52 to 67.88)). However, our results did not suggest any interaction on a multiplicative scale. Conclusions Our results suggest that asbestos exposure, in combination with tobacco and alcohol exposure, accounted for a substantial number of laryngeal cancer cases. Our findings therefore highlight the need for prevention in activities, such as construction work, where exposure to asbestos-containing materials remains

Published
2015
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2. Risk of lung cancer associated with occupational exposure to mineral wools: updating knowledge from a french population-based case-control study, the ICARE study

Author

Annie Schmaus, Farida Lamkarkach, Loredana Radoï, Sylvie Cénée, Stéphane Ducamp, Alexandra Papadopoulos, Florence Guida, Florence Molinié, Joelle Fevotte, Sophie Paget-Bailly, Gwenn Menvielle, Diane Cyr, Bénédicte Lapôtre-Ledoux, Matthieu Carton, Isabelle Stücker, Danièle Luce, Mireille Matrat, and Oumar Gaye

Subjects
Adult, Male, Lung Neoplasms, Adolescent, Cumulative Exposure, Air Pollutants, Occupational, medicine.disease_cause, Asbestos, Young Adult, Risk Factors, Environmental health, Occupational Exposure, Surveys and Questionnaires, medicine, Humans, Young adult, Lung cancer, Aged, business.industry, Silicates, Smoking, Public Health, Environmental and Occupational Health, Case-control study, Odds ratio, Calcium Compounds, Middle Aged, medicine.disease, Silicon Dioxide, Confidence interval, Occupational Diseases, Logistic Models, Quartile, Case-Control Studies, France, business
Abstract

Objectives To assess the risk of lung cancer associated with exposure to mineral wools (MWs), while taking into account smoking, asbestos, and crystalline silica exposures. Methods The analyses were restricted to men (1350 cases and 1912 controls). Lifelong occupational history was collected. MWs and asbestos exposures were assessed, using task-exposure matrices and silica exposure, a job-exposure matrix. Results We observed consistent not-significant increased risks of lung cancer of the same order of magnitude among workers exposed to high levels of MWs (odds ratio, 1.4; 95% confidence interval: 0.9 to 2.2; for highest quartile of the Cumulative Exposure Index). Conclusions These results do not allow to draw firm conclusion about a carcinogenic effect of MWs on the lung, but they cannot exclude it. Given the high number of potentially exposed workers, it will be necessary to replicate them in a future further removed from the asbestos ban.

Published
2013

3. Night work and breast cancer: a population-based case-control study in France (the CECILE study)

Author

Florence Menegaux, Patrick Arveux, Thérèse Truong, J. Fevotte, Pascal Guénel, Emilie Cordina-Duverger, Antoinette Anger, Farida Lamkarkach, and Pierre Kerbrat

Subjects
Gerontology, Adult, Employment, Cancer Research, Population, Breast Neoplasms, Breast cancer, Pregnancy, Risk Factors, Work Schedule Tolerance, medicine, Humans, Circadian rhythm, Occupations, education, Night work, Aged, education.field_of_study, business.industry, Case-control study, Odds ratio, Middle Aged, medicine.disease, Confidence interval, Circadian Rhythm, Oncology, Case-Control Studies, Female, France, business, Demography
Abstract

Night work involving disruption of circadian rhythm was suggested as a possible cause of breast cancer. We examined the role of night work in a large population-based case-control study carried out in France between 2005 and 2008. Lifetime occupational history including work schedules of each night work period was elicited in 1,232 cases of breast cancer and 1,317 population controls. Thirteen percent of the cases and 11% of the controls had ever worked on night shifts (OR = 1.27 [95% confidence interval = 0.99–1.64]). Odds ratios were 1.35 [1.01–1.80] in women who worked on overnight shifts, 1.40 [1.01–1.92] in women who had worked at night for 4.5 or more years, and 1.43 [1.01–2.03] in those who worked less than three nights per week on average. The odds ratio was 1.95 [1.13–3.35] in women employed in night work for >4 years before their first full-term pregnancy, a period where mammary gland cells are incompletely differentiated and possibly more susceptible to circadian disruption effects. Our results support the hypothesis that night work plays a role in breast cancer, particularly in women who started working at night before first full-term pregnancy.

Published
2012

4. Breast cancer risk by occupation and industry: analysis of the CECILE study, a population-based case-control study in France

Author

Pierre Kerbrat, Pascal Guénel, Sara Villeneuve, Oumar Gaye, Farida Lamkarkach, Patrick Arveux, Thérèse Truong, Antoinette Anger, J. Fevotte, Ellen Imbernon, and Laurent Miglianico

Subjects
Adult, Population, Breast Neoplasms, Breast cancer, Risk Factors, Environmental health, Occupational Exposure, Surveys and Questionnaires, Confidence Intervals, Odds Ratio, Medicine, Humans, Industry, education, Aged, education.field_of_study, business.industry, Incidence (epidemiology), Incidence, Public Health, Environmental and Occupational Health, Case-control study, Odds ratio, Middle Aged, medicine.disease, Confidence interval, Occupational Diseases, Risk factors for breast cancer, Case-Control Studies, Etiology, Carcinogens, Female, France, business
Abstract

Background It has been suggested that certain occupational exposures may play a role in breast cancer etiology. The recognition of high-risk occupations may give clues about potential mammary carcinogens in the work place. Methods We conducted a population-based case–control study in France including 1,230 breast cancer cases and 1,315 population controls with detailed information on lifetime work history. Odds ratios for women ever employed in an occupation or industry were adjusted for well-established risk factors for breast cancer. Results Adjusted odds ratios were marginally increased in some white-collar occupations, as well as in textile workers (2.4; 95% CI [0.9–6.0]), rubber and plastics product makers (1.8; 95% CI [0.9–3.5]), and in women employed for more than 10 years as nurses (1.4; 95% CI [0.9–2.1]) and as tailors/dressmakers (1.5; 95% CI [0.9–2.6]). The incidence of breast cancer was increased among women employed in the manufacture of chemicals, of non-metallic mineral products, and decreased among women in agriculture. Conclusions These findings suggest a possible role of occupational exposures in breast cancer, including night-shift work, solvents and endocrine disrupting chemicals and require further studies with detailed assessment of occupational exposures. Am. J. Ind. Med. 54:499–509, 2011. © 2011 Wiley-Liss, Inc.

Published
2011

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