13 results on '"Carraro E"'
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2. The role of rehabilitation in the management of late-onset Pompe disease: a narrative review of the level of evidence
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Giovanni Iolascon, Vitacca, M., Carraro, E., Chisari, C., Fiore, P., Messina, S., Giovanna Mongini, T. E., Sansone, V. A., Toscano, A., Siciliano, G., Iolascon, Giovanni, Vitacca, Michele, Carraro, Elena, Chisari, Carmelo, Fiore, Pietro, Messina, Sonia, Enrica Giovanna Mongini, Tiziana, Sansone, Valeria A., Toscano, Antonio, and Siciliano, Gabriele
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Glycogen Storage Disease Type II ,Respiration ,motor function ,late-onset Pompe disease ,rehabilitation ,Exercise Therapy ,endurance and resistance training ,respiratory function ,Activities of Daily Living ,Age of Onset ,Humans ,Italy ,Motor Skills ,Quality of Life ,Original Article - Abstract
Late-onset Pompe disease (LOPD) is characterized by progressive muscle weakness, respiratory muscle dysfunction, and minor cardiac involvement. Although in LOPD, as in other neuromuscular diseases, controlled low impact sub-maximal aerobic exercise and functional ability exercise can improve general functioning and quality of life, as well as respiratory rehabilitation, the bulk of evidence on that is weak and guidelines are lacking. To date, there is no specific focus on rehabilitation issues in clinical recommendations for the care of patients with Pompe disease, and standard practice predominantly follows general recommendation guidelines for neuromuscular diseases. The Italian Association of Myology, the Italian Association of Pulmonologists, the Italian Society of Neurorehabilitation, and the Italian Society of Physical Medicine and Rehabilitation, have endorsed a project to formulate recommendations on practical, technical, and, whenever possible, disease-specific guidance on rehabilitation procedures in LOPD, with specific reference to the Italian scenario. In this first paper, we review available evidence on the role of rehabilitation in LOPD patients, particularly addressing the unmet needs in the management of motor and respiratory function for these patients. Late-onset Pompe disease (LOPD) is characterized by progressive muscle weakness, respiratory muscle dysfunction, and minor cardiac involvement. Although in LOPD, as in other neuromuscular diseases, controlled low impact sub-maximal aerobic exercise and functional ability exercise can improve general functioning and quality of life, as well as respiratory rehabilitation, the bulk of evidence on that is weak and guidelines are lacking. To date, there is no specific focus on rehabilitation issues in clinical recommendations for the care of patients with Pompe disease, and standard practice predominantly follows general recommendation guidelines for neuromuscular diseases. The Italian Association of Myology, the Italian Association of Pulmonologists, the Italian Society of Neurorehabilitation, and the Italian Society of Physical Medicine and Rehabilitation, have endorsed a project to formulate recommendations on practical, technical, and, whenever possible, disease-specific guidance on rehabilitation procedures in LOPD, with specific reference to the Italian scenario. In this first paper, we review available evidence on the role of rehabilitation in LOPD patients, particularly addressing the unmet needs in the management of motor and respiratory function for these patients.
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- 2019
3. monitoring air pollution effects on children for supporting public health policy: the protocol of the prospective cohort MAPEC study
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Feretti, D., Ceretti, E., Moretti, M., Carducci, A., Bonetta, S., Marrese, M. R., Bonetti, A., Covolo, L., Villarini, M., Verani, M., Schilirò, T., Limina, R. M., Monarca, S., Casini, B., Carraro, E., Zani, C., Mazzoleni, G., Levaggi, R., Gelatti, U., Compiani, S., Donato, F., Festa, A., Viola, G. C. V., Zerbini, I., Idolo, A., Serio, F., Tumolo, M. R., Dominici, L., Fatigoni, C., Levorato, S., Peverini, M., Vannini, S., Bruni, B., Caponi, E., Donzelli, G., Gilli, G., Pignata, C., Bonizzoni, S., Furia, C., Braga, F., Codenotti, R., Colombi, P., Lini, D., Mario, E., DE DONNO, Maria Antonella, BAGORDO, Francesco, GRASSI, Tiziana, GUIDO, Marcello, VERRI, Tiziano, Feretti, D., Ceretti, E., DE DONNO, Maria Antonella, Moretti, M., Carducci, A., Bonetta, S., Marrese, M. R., Bonetti, A., Covolo, L., Bagordo, Francesco, Villarini, M., Verani, M., Schilirò, T., Limina, R. M., Grassi, Tiziana, Monarca, S., Casini, B., Carraro, E., Zani, C., Mazzoleni, G., Levaggi, R., Gelatti, U., Compiani, S., Donato, F., Festa, A., Viola, G. C. V., Zerbini, I., Guido, Marcello, Idolo, A., Serio, F., Tumolo, M. R., Verri, Tiziano, Dominici, L., Fatigoni, C., Levorato, S., Peverini, M., Vannini, S., Bruni, B., Caponi, E., Donzelli, G., Gilli, G., Pignata, C., Bonizzoni, S., Furia, C., Braga, F., Codenotti, R., Colombi, P., Lini, D., Mario, E., Feretti, D, Ceretti, E, Moretti, M, Carducci, A, Bonetta, S, Marrese, M. R, Bonetti, A, Covolo, L, Villarini, M, Verani, M, Schilirò, T, Limina, R. M, Monarca, S, Casini, B, Carraro, E, Zani, C, Mazzoleni, G, and Levaggi, R
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COMET ASSAY ,air pollution ,Air pollution ,SALMONELLA MUTAGENICITY ,environmental pollution ,Public health ,child health ,Mutagenesis ,mucosa buccal cell ,medicine.disease_cause ,MICRONUCLEUS FREQUENCY ,Epidemiology ,Environmental monitoring ,Protocol ,Prospective Studies ,Child ,ENVIRONMENTAL-POLLUTANTS ,Health Policy ,Absolute risk reduction ,General Medicine ,PERIPHERAL-BLOOD LYMPHOCYTES ,Public Health ,mucosa buccal cells ,Human ,Environmental Monitoring ,medicine.medical_specialty ,EUROPEAN COHORTS ,AMBIENT AIR ,DNA damage ,PUBLIC HEALTH ,children ,early biological effect ,Air Pollution ,Humans ,Medicine (all) ,Environmental health ,medicine ,EXPOSURE ,Socioeconomic status ,Health policy ,Pollutant ,GENETIC-DAMAGE ,business.industry ,IN-VITRO ,Prospective Studie ,business - Abstract
Introduction Genotoxic biomarkers have been studied largely in adult population, but few studies so far have investigated them in children exposed to air pollution. Children are a high-risk group as regards the health effects of air pollution and some studies suggest that early exposure during childhood can play an important role in the development of chronic diseases in adulthood. The objective of the project is to evaluate the associations between the concentration of urban air pollutants and biomarkers of early biological effect in children, and to propose a model for estimating the global risk of early biological effects due to air pollutants and other factors in children. Methods and analysis Two biomarkers of early biological effects, DNA damage by the comet assay and the micronuclei (MN) test, will be investigated in oral mucosa cells of 6–8-year-old children. Concurrently, some toxic airborne pollutants (polycyclic aromatic hydrocarbon (PAH) and nitro-PAH) and in vitro air mutagenicity and toxicity in ultra-fine air particulates (PM0.5) will be evaluated. Furthermore, demographic and socioeconomic variables, other sources of exposures to air pollutants and lifestyle variables will be assessed by a structured questionnaire. The associations between sociodemographic, environmental and other exposure variables and biomarkers of early biological effect using univariate and multivariate models will be analysed. A tentative model for calculating the global absolute risk of having early biological effects caused by air pollution and other variables will be proposed. Ethics and dissemination The project has been approved by the Ethics Committees of the local Health Authorities. The results will be communicated to local Public Health Agencies, for supporting educational programmes and health policy strategies. LIFE+2012 Environment Policy and Governance. LIFE12 ENV/IT/000614.
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- 2014
4. Mediastinal Burkitt lymphoma in childhood
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Pillon, M, Aricò, M, Mussolin, Lara, Mainardi, Chiara, Giraldi, E, Garaventa, A, Lombardi, A, Santoro, N, Carraro, E, D'Amore, Es, Rosolen, A, and Italian Association of Pediatric Hematology Oncology AIEOP Non Hodgkin Lymphoma Working Group
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Male ,Adolescent ,Child, Preschool ,Humans ,Female ,Child ,Burkitt Lymphoma ,Mediastinal Neoplasms - Published
- 2014
5. The Locomotory Index in diplegic and hemiplegic children: the effects of age and speed on the energy cost of walking
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Marconi, V., Carraro, E., Trevisi, E., Capelli, C., Andrea Martinuzzi, and Zamparo, P.
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Male ,Paraplegia ,cerebral palsy ,Adolescent ,Hemiplegia ,Walking ,Gait ,oxygen consumption ,locomotion ,energy metabolism ,Disability Evaluation ,Child, Preschool ,Humans ,Disabled Persons ,Female ,Child - Abstract
The energy cost of locomotion (C) is a useful tool for quantifying the level of walking disability in the clinical evaluation of patients with cerebral palsy (CP). In addition to clinical condition, also age and velocity (v) can influence C, a fact that is often overlooked.To show: i) that C differs in the clinical subtypes of CP (hemiplegia or diplegia) and ii) that C should be measured at comparable speeds in CP patients and controls (of the same age).Controlled study.Pediatric Rehabilitation Unit of "E. Medea" Scientific Institute (Conegliano, TV); Exercise Physiology Lab of University of Verona.Forty-three CP children (32 diplegic: Dg; 11 hemiplegic: Hg) and 20 healthy children (Cg) with an age range of 4-14 years.C was measured as the ratio of net oxygen uptake to walking speed (at v from 1 to 6 km·h(-1)). The Locomotory index (LI) was calculated as the ratio of C in Dg/Hg and Cg (of the same age) at the same speed.C decreases with increasing speed in all groups but evolves differently in Hg and Dg: in the former C decreases by increasing age, becoming similar to that of Cg at 12-14 years; in the latter C does not change as a function of age being always larger than in Cg.Our data highlight the reduction in C with increasing speed and suggest a better prognosis of locomotion for Hg compared to Dg.
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- 2012
6. Time for a consensus conference on pain in neurorehabilitation
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Sandrini, G, Tamburin, S, Paolucci, S, Boldrini, P, Saraceni, V, Smania, N, Italian Consensus Conference on Pain in Neurorehabilitation, Agostini, M, Alfonsi, E, Aloisi, A, Alvisi, E, Aprile, I, Armando, M, Avenali, M, Azicnuda, E, Barale, F, Bartolo, M, Bergamaschi, R, Berlangieri, M, Berlincioni, V, Berliocchi, L, Berra, E, Berto, G, Bonadiman, S, Bonazza, S, Bressi, F, Brugnera, A, Brunelli, S, Buzzi, M, Cacciatori, C, Calvo, A, Cantarella, C, Caraceni, A, Carone, R, Carraro, E, Casale, R, Castellazzi, P, Castelnuovo, G, Castino, A, Cella, M, Cerbo, R, Chiò, A, Ciotti, C, Cisari, C, Coraci, D, Dalla Toffola, E, Defazio, G, De Icco, R, Del Carro, U, Dell’Isola, A, De Tanti, A, D’Ippolito, M, Fazzi, E, Federico, A, Ferrari, A, Ferrari, S, Ferraro, F, Formaglio, F, Formisano, R, Franzoni, S, Gajofatto, F, Gandolfi, M, Gardella, B, Geppetti, P, Giammò, A, Gimigliano, R, Giusti, E, Greco, E, Ieraci, V, Invernizzi, M, Jacopetti, M, Jedrychowska, I, Lacerenza, M, La Cesa, S, Lobba, D, Magrinelli, F, Mandrini, S, Manera, U, Manzoni, G, Marchettini, P, Marchioni, E, Mariotto, S, Martinuzzi, A, Masciullo, M, Mezzarobba, S, Miotti, D, Modenese, A, Molinari, M, Monaco, S, Morone, G, Nappi, R, Negrini, S, Pace, A, Padua, L, Pagliano, E, Palmerini, V, Pazzaglia, C, Pecchioli, C, Pietrabissa, G, Picelli, A, Polli, A, Porro, C, Porru, D, Romano, M, Roncari, L, Rosa, R, Saccavini, M, Sacerdote, P, Saviola, D, Schenone, A, Schweiger, V, Scivoletto, G, Solaro, C, Spallone, V, Springhetti, I, Tassorelli, C, Tinazzi, M, Togni, R, Torre, M, Torta, R, Traballesi, M, Trabucco, E, Tramontano, M, Truini, A, Tugnoli, V, Turolla, A, Valeriani, M, Vallies, G, Verzini, E, Vottero, M, Mario, P, Sandrini, Giorgio, Tamburin, Stefano, Paolucci, Stefano, Boldrini, Paolo, Saraceni, Vincenzo M., Smania, Nicola, Agostini, Michela, Alfonsi, Enrico, Aloisi, Anna Maria, Alvisi, Elena, Aprile, Irene, Armando, Michela, Avenali, Micol, Azicnuda, Eva, Barale, Francesco, Bartolo, Michelangelo, Bergamaschi, Roberto, Berlangieri, Mariangela, Berlincioni, Vanna, Berliocchi, Laura, Berra, Eliana, Berto, Giulia, Bonadiman, Silvia, Bonazza, Sara, Bressi, Federica, Brugnera, Annalisa, Brunelli, Stefano, Buzzi, Maria Gabriella, Cacciatori, Carlo, Calvo, Andrea, Cantarella, Cristina, Caraceni, Augusto Tommaso, Carone, Roberto, Carraro, Elena, Casale, Roberto, Castellazzi, Paola, Castelnuovo, Gianluca, Castino, Adele, Cella, Monica, Cerbo, Rosanna, Chiò, Adriano, Ciotti, Cristina, Cisari, Carlo, Coraci, Daniele, Toffola, Elena Dalla, Defazio, Giovanni, De Icco, Roberto, Del Carro, Ubaldo, Dell'Isola, Andrea, De Tanti, Antonio, D'Ippolito, Mariagrazia, Fazzi, Elisa, Federico, Angela, Ferrari, Adriano, Ferrari, Sergio, Ferraro, Francesco, Formaglio, Fabio, Formisano, Rita, Franzoni, Simone, Gajofatto, Francesca, Gandolfi, Marialuisa, Gardella, Barbara, Geppetti, Pierangelo, Giammò, Alessandro, Gimigliano, Raffaele, Giusti, Emanuele Maria, Greco, Elena, Ieraci, Valentina, Invernizzi, Marco, Jacopetti, Marco, Jedrychowska, Iwona, Lacerenza, Marco, La Cesa, Silvia, Lobba, Davide, Magrinelli, Francesca, Mandrini, Silvia, Manera, Umberto, Manzoni, Gian Mauro, Marchettini, Paolo, Marchioni, Enrico, Mariotto, Sara, Martinuzzi, Andrea, Masciullo, Marcella, Mezzarobba, Susanna, Miotti, Danilo, Modenese, Angela, Molinari, Marco, Monaco, Salvatore, Morone, Giovanni, Nappi, Rossella, Negrini, Stefano, Pace, Andrea, Padua, Luca, Pagliano, Emanuela, Palmerini, Valerio, Pazzaglia, Costanza, Pecchioli, Cristiano, Pietrabissa, Giada, Picelli, Alessandro, Polli, Andrea, Porro, Carlo Adolfo, Porru, Daniele, Romano, Marcello, Roncari, Laura, Rosa, Riccardo, Saccavini, Marsilio, Sacerdote, Paola, Saviola, Donatella, Schenone, Angelo, Schweiger, Vittorio, Scivoletto, Giorgio, Solaro, Claudio, Spallone, Vincenza, Springhetti, Isabella, Tassorelli, Cristina, Tinazzi, Michele, Togni, Rossella, Torre, Monica, Torta, Riccardo, Traballesi, Marco, Trabucco, Erika, Tramontano, Marco, Truini, Andrea, Tugnoli, Valeria, Turolla, Andrea, Valeriani, Massimiliano, Vallies, Gabriella, Verzini, Elisabetta, Vottero, Mario, and Zerbinati, Paolo
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Male ,peripheral neuropathy ,Time Factors ,Physical Therapy ,consensus conference ,Consensus Development Conferences as Topic ,Sports Therapy and Rehabilitation ,Settore M-PSI/08 - PSICOLOGIA CLINICA ,pain ,diabetic neuropathy ,neurorehabilitation ,neuropathic pain ,Settore MED/13 - Endocrinologia ,Humans ,Pain Management ,Randomized Controlled Trials as Topic ,Physical Therapy, Sports Therapy and Rehabilitation ,Rehabilitation ,Female ,Italy ,Neurological Rehabilitation ,neurorehabilitation, pain, consensus conference ,Settore MED/34 - Medicina Fisica e Riabilitativa ,Settore MED/26 - Neurologia ,Human
7. The rapid spread of SARS-COV-2 Omicron variant in Italy reflected early through wastewater surveillance
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La Rosa, G., Iaconelli, M., Veneri, C., Mancini, P., Bonanno Ferraro, G., Brandtner, D., Lucentini, L., Bonadonna, L., Rossi, M., Grigioni, M., Suffredini, E., Giuseppe, Bucciarelli, Paolo, Torlontano, Giuseppe, Michele La Bianca, Rosa Anna Cifarelli, Achille, Palma, Giovanna La Vecchia, Giuseppe, Lauria, Rosanna, Brienza, Patrizia, Montenegro, Angelo, D'Argenzio, Luigi, Cossentino, Renato, Olivares, Antonio, Pizzolante, Giovanna, Fusco, Alessandra, Tosco, Amalia, Porta, Francesca, Pennino, Triassi, Maria, Paola, Angelini, Laura De Lellis, Daniele, Nasci, Giovanni, Alborali, Nicoletta, Formenti, Flavia, Guarneri, Nadia, Fontani, Giulia, Nani, Franca, Palumbo, Gianluca, Borlone, Marco, Guercio, Lisa, Gentili, Marika, Mariuz, Gabriella, Trani, Anna, Pariani, Carla, Ancona, Doriana Antonella Giorgi, Irene, Ferrante, Monica, Monfrinotti, Silvia, Riosa, Valeria, Capparuccini, Maria Teresa Scicluna, Antonella, Mariaconcetta, Arizzi, Giancarlo, Cecchini, Claudio, Ottaviano, Elena, Nicosia, Elena, Grasselli, Giorgia, Allaria, Alberto, Izzotti, Stefano, Rosatto, Emanuela, Ammoni, Danilo, Cereda, Marina Nadia Losio, Barbara, Bertasi, Andrea, Aliscioni, Desdemona, Oliva, Sara, Castiglioni, Silvia, Schiarea, Ettore, Zuccato, Manuela, Antonelli, Arianna, Azzellino, Francesca, Malpei, Andrea, Turolla, Sandro, Binda, Pellegrinelli, Laura, Valeria, Primache, Clementina, Cocuzza, Andrea, Franzetti, Giorgio, Bertanza, Maria Luisa Callegari, Luigi, Bolognini, Fabio, Filippetti, Marta, Paniccia, Francesca, Ciuti, Sara, Briscolini, Silvia, Magi, Michele, Colitti, Carmen, Montanaro, Giuseppe, Aprea, Maria Grazia Cerroni, Bartolomeo, Griglio, Renza, Berruti, Mauro, Cravero, Angela, Costa, Manila, Bianchi, Lucia, Decastelli, Angelo, Romano, Fabio, Zuccon, Elisabetta, Carraro, Cristina, Pignata, Silvia, Bonetta, Giuseppe Di Vittorio, Onofrio, Mongelli, Osvalda De Giglio, Francesca, Apollonio, Francesco, Triggiano, Maria Teresa Montagna, Nicola, Ungaro, Mario, Palermo, Carmelo Massimo Maida, Walter, Mazzucco, Simona De Grazia, Giovanni, Giammanco, Giuseppa, Purpari, Margherita, Ferrante, Antonella, Agodi, Martina, Barchitta, Piergiuseppe, Cala’, Carducci, Annalaura, Verani, Marco, Federigi, Ileana, Giulia, Lauretani, Sara, Muzio, Matteo, Ramazzotti, Alberto, Antonelli, Enrica, Ricci, Giovanni, Santoro, Ermanno, Federici, Maya, Petricciuolo, Sofia, Barigelli, Mauro, Ruffier, Francesca, Borney, Eric, Grange, Florida, Damasco, Francesca, Russo, Gisella, Pitter, Vanessa, Groppi, Franco, Rigoli, Marco, Zampini, Tatjana, Baldovin, Irene, Amoruso, Elena, Mengon, Maria, Cadonna, Mattia, Postinghel, Francesco, Pizzo, Alessandra, Schiavuzzi, Francesca, Cutrupi, Paola, Foladori, Serena, Manara, Lorella, Zago, Alberta, Stenico, Anna-Maria, Prast., La Rosa, G, Iaconelli, M, Veneri, C, Mancini, P, Bonanno Ferraro, G, Brandtner, D, Lucentini, L, Bonadonna, L, Rossi, M, Grigioni, M, Suffredini, E, Bucciarelli, G, Torlontano, P, Aprea, G, La Bianca, M, Cifarelli, R, Palma, A, La Vecchia, G, Lauria, G, Brienza, R, Montenegro, P, D'Argenzio, A, Cossentino, L, Olivares, R, Pizzolante, A, Fusco, G, Tosco, A, Porta, A, Pennino, F, Maria, T, Angelini, P, De Lellis, L, Nasci, D, Alborali, G, Formenti, N, Guarneri, F, Fontani, N, Nani, G, Palumbo, F, Borlone, G, Guercio, M, Gentili, L, Mariuz, M, Trani, G, Pariani, A, Ancona, C, Giorgi, D, Ferrante, I, Monfrinotti, M, Riosa, S, Capparuccini, V, Scicluna, M, Cersini, A, Arizzi, M, Cecchini, G, Ottaviano, C, Nicosia, E, Grasselli, E, Allaria, G, Izzotti, A, Rosatto, S, Ammoni, E, Cereda, D, Losio, M, Bertasi, B, Aliscioni, A, Oliva, D, Castiglioni, S, Schiarea, S, Zuccato, E, Antonelli, M, Azzellino, A, Malpei, F, Turolla, A, Binda, S, Laura, P, Primache, V, Cocuzza, C, Franzetti, A, Bertanza, G, Callegari, M, Bolognini, L, Filippetti, F, Paniccia', M, Ciuti, F, Briscolini, S, Magi, S, Colitti, M, Montanaro, C, Cerroni, M, Griglio, B, Berruti, R, Cravero, M, Costa, A, Bianchi, M, Decastelli, L, Romano, A, Zuccon, F, Carraro, E, Pignata, C, Bonetta, S, Di Vittorio, G, Mongelli, O, De Giglio, O, Apollonio, F, Triggiano, F, Montagna, M, Ungaro, N, Palermo, M, Maida, C, Mazzucco, W, De Grazia, S, Giammanco, G, Purpari, G, Ferrante, M, Agodi, A, Barchitta, M, Cala', P, Carducci, A, Verani, M, Federigi, I, Lauretani, G, Muzio, S, Ramazzotti, M, Antonelli, A, Ricci, E, Santoro, G, Federici, E, Petricciuolo, M, Barigelli, S, Ruffier, M, Borney, F, Grange, E, Damasco, F, Russo, F, Pitter, G, Groppi, V, Rigoli, F, Zampini, M, Baldovin, T, Amoruso, I, Mengon, E, Cadonna, M, Postinghel, M, Pizzo, F, Schiavuzzi, A, Cutrupi, F, Foladori, P, Manara, S, Zago, L, Stenico, A, Prast, A, La Rosa G., Iaconelli M., Veneri C., Mancini P., Bonanno Ferraro G., Brandtner D., Lucentini L., Bonadonna L., Rossi M., Grigioni M., Bucciarelli G., Torlontano P., Aprea G., La Bianca M., Cifarelli R.A., Palma A., La Vecchia G., Lauria G., Brienza R., Montenegro P., D'Argenzio A., Cossentino L., Olivares R., Pizzolante A., Fusco G., Tosco A., Porta A., Pennino F., Maria T., Angelini P., De Lellis L., Nasci D., Alborali G., Formenti N., Guarneri F., Fontani N., Nani G., Palumbo F., Borlone G., Guercio M., Gentili L., Mariuz M., Trani G., Pariani A., Ancona C., Giorgi D.A., Ferrante I., Monfrinotti M., Riosa S., Capparuccini V., Scicluna M.T., Cersini A., Arizzi M., Cecchini G., Ottaviano C., Nicosia E., Grasselli E., Allaria G., Izzotti A., Rosatto S., Ammoni E., Cereda D., Losio M.N., Bertasi B., Aliscioni A., Oliva D., Castiglioni S., Schiarea S., Zuccato E., Antonelli M., Azzellino A., Malpei F., Turolla A., Binda S., Laura P., Primache V., Cocuzza C., Franzetti A., Bertanza G., Callegari M.L., Bolognini L., Filippetti F., Paniccia' M., Ciuti F., Briscolini S., Magi S., Colitti M., Montanaro C., Cerroni M.G., Griglio B., Berruti R., Cravero M., Costa A., Bianchi M., Decastelli L., Romano A., Zuccon F., Carraro E., Pignata C., Bonetta S., Di Vittorio G., Mongelli O., De Giglio O., Apollonio F., Triggiano F., Montagna M.T., Ungaro N., Palermo M., Maida C.M., Mazzucco W., De Grazia S., Giammanco G., Purpari G., Ferrante M., Agodi A., Barchitta M., Cala' P., Carducci A., Verani M., Federigi I., Lauretani G., Muzio S., Ramazzotti M., Antonelli A., Ricci E., Santoro G., Federici E., Petricciuolo M., Barigelli S., Ruffier M., Borney F., Grange E., Damasco F., Russo F., Pitter G., Groppi V., Rigoli F., Zampini M., Baldovin T., Amoruso I., Mengon E., Cadonna M., Postinghel M., Pizzo F., Schiavuzzi A., Cutrupi F., Foladori P., Manara S., Zago L., Stenico A., Prast A.-M., Suffredini E., and Triassi, M
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Omicron ,RT-qPCR ,SARS-CoV-2 ,Sewage ,Variant ,Wastewater-based epidemiology ,Wastewater-Based Epidemiological Monitoring ,Environmental Engineering ,COVID-19 ,Wastewater ,Pollution ,Humans ,RNA, Viral ,Waste Water ,SARS-Cov2 ,Environmental Chemistry ,RNA ,Viral ,wastewater based epidemiology ,Waste Management and Disposal ,Human ,Omicron, RT-qPCR, SARS-CoV-2, Sewage, Variant, Wastewater-based epidemiology - Abstract
The SARS-CoV-2 Omicron variant emerged in South Africa in November 2021, and has later been identified worldwide, raising serious concerns. A real-time RT-PCR assay was designed for the rapid screening of the Omicron variant, targeting characteristic mutations of the spike gene. The assay was used to test 737 sewage samples collected throughout Italy (19/21 Regions) between 11 November and 25 December 2021, with the aim of assessing the spread of the Omicron variant in the country. Positive samples were also tested with a real-time RT-PCR developed by the European Commission, Joint Research Centre (JRC), and through nested RT-PCR followed by Sanger sequencing. Overall, 115 samples tested positive for Omicron SARS-CoV-2 variant. The first occurrence was detected on 7 December, in Veneto, North Italy. Later on, the variant spread extremely fast in three weeks, with prevalence of positive wastewater samples rising from 1.0% (1/104 samples) in the week 5-11 December, to 17.5% (25/143 samples) in the week 12-18, to 65.9% (89/135 samples) in the week 19-25, in line with the increase in cases of infection with the Omicron variant observed during December in Italy. Similarly, the number of Regions/Autonomous Provinces in which the variant was detected increased from one in the first week, to 11 in the second, and to 17 in the last one. The presence of the Omicron variant was confirmed by the JRC real-time RT-PCR in 79.1% (91/115) of the positive samples, and by Sanger sequencing in 66% (64/97) of PCR amplicons. In conclusion, we designed an RT-qPCR assay capable to detect the Omicron variant, which can be successfully used for the purpose of wastewater-based epidemiology. We also described the history of the introduction and diffusion of the Omicron variant in the Italian population and territory, confirming the effectiveness of sewage monitoring as a powerful surveillance tool.
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- 2022
8. Predicting needlestick and sharps injuries in nursing students: Development of the SNNIP scale
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Milko Zanini, Christian Napoli, Alessia Manca, Leandro Gentile, Leila Fabiani, Elena Righi, Tiziana Traini, Marzia Montesano, Emanuela Santoro, Roberta Magnano San Lio, Gianluca Catania, Francesca Moretti, A Zerbetto, Mark Hayter, Beatrice Casini, C Genovese, I. Torre, Loredana Sasso, Giuseppe Calamusa, Ilaria Barberis, Nicoletta Dasso, Giovanni Battista Orsi, Cristina Arrigoni, Annamaria Bagnasco, Stefania Berdini, Anna Maria Iannicelli, Alberto Carli, Alborz Rahmani, Roger Watson, Tiziana Benedetti, Barbara Bascapè, Silvia D'Eugenio, Alberto Borraccino, Adoriano Santarelli, Raffaele Squeri, Martina Barchitta, Marco Verani, Antonio Perre, Simona Mascipinto, Mariana Sao Miguel Morgado, Lucia Palandri, Smeralda D'Amato, Maria Teresa Montagna, Giuliana Favara, Licia Veronesi, Alfredo Montecucco, Matteo Riccò, Maria Valeria Torregrossa, E Bertamino, Antonella Agodi, Vincenza La Fauci, Annalisa Bargellini, Arda Sulaj, Alberto Firenze, Ida Mura, Roberto Novati, Nicola Magnavita, Reparata Rosa Di Prinzio, Francesca Maria Bersi, Tatjana Baldovin, Sandro Ortolani, Carla Maria Zotti, Rita Fiorentini, Roberta Oriani, Marcello Mario D’Errico, Francesca Pennino, Ada Bianco, Andrea Maugeri, Anna Rita Giuliani, Giovanni Sotgiu, Paola Ferri, Valeria Teti, Edoardo Tartaglia, A Rossini, Angelo Baggiani, Guglielmo Dini, Sonia Zacconi, Daniela Schiavone, Leandra Giudice, Cesira Pasquarella, Sara Dalla Torre, Giovanni Boccia, Maria Chiara Ottino, Maurizio Mercuri, Paolo Durando, Stefano Tardivo, Emanuela Massa, Elisabetta Carraro, Deborah Traversi, Bagnasco A., Zanini M., Catania G., Watson R., Hayter M., Dasso N., Dini G., Agodi A., Pasquarella C., Zotti C.M., Durando P., Sasso L., Barchitta M., Maugeri A., Favara G., San Lio R.M., Rossini A., Squeri R., Genovese C., D'Amato S., La Fauci V., Tardivo S., Moretti F., Carli A., Casini B., Baggiani A., Verani M., Rita Giuliani A., Fabiani L., D'Eugenio S., Boccia G., Santoro E., Battista Orsi G., Napoli C., Montesano M., Berdini S., Bertamino E., Perre A., Zerbetto A., D'Errico M., Ortolani S., Mercuri M., Traini T., Santarelli A., Fiorentini R., Benedetti T., Montagna M., Mascipinto S., Torre I., Pennino F., Schiavone D., Maria Iannicelli A., Tartaglia E., Veronesi L., Palandri L., Miguel Morgado M.S., Giudice L., Arrigoni C., Gentile L., Bascape B., Mura I., Sotgiu G., Barberis I., Maria Bersi F., Manca A., Massa E., Montecucco A., Rahmani A., Zacconi S., Ricco M., Magnavita N., Di Prinzio R.R., Torregrossa M.V., Calamusa G., Firenze A., Bargellini A., Ferri P., Righi E., Carraro E., Borraccino A., Traversi D., Ottino M.C., Baldovin T., Torre S.D., Sulaj A., Bianco A., Teti V., Novati R., Oriani R., Bagnasco, A., Zanini, M., Catania, G., Watson, R., Hayter, M., Dasso, N., Dini, G., Agodi, A., Pasquarella, C., Zotti, C. M., Durando, P., Sasso, L., Barchitta, M., Maugeri, A., Favara, G., San Lio, R. M., Rossini, A., Squeri, R., Genovese, C., D'Amato, S., La Fauci, V., Tardivo, S., Moretti, F., Carli, A., Casini, B., Baggiani, A., Verani, M., Rita Giuliani, A., Fabiani, L., D'Eugenio, S., Boccia, G., Santoro, E., Battista Orsi, G., Napoli, C., Montesano, M., Berdini, S., Bertamino, E., Perre, A., Zerbetto, A., D'Errico, M., Ortolani, S., Mercuri, M., Traini, T., Santarelli, A., Fiorentini, R., Benedetti, T., Montagna, M., Mascipinto, S., Torre, I., Pennino, F., Schiavone, D., Maria Iannicelli, A., Tartaglia, E., Veronesi, L., Palandri, L., Miguel Morgado, M. S., Giudice, L., Arrigoni, C., Gentile, L., Bascape, B., Mura, I., Sotgiu, G., Barberis, I., Maria Bersi, F., Manca, A., Massa, E., Montecucco, A., Rahmani, A., Zacconi, S., Ricco, M., Magnavita, N., Di Prinzio, R. R., Torregrossa, M. V., Calamusa, G., Firenze, A., Bargellini, A., Ferri, P., Righi, E., Carraro, E., Borraccino, A., Traversi, D., Ottino, M. C., Baldovin, T., Torre, S. D., Sulaj, A., Bianco, A., Teti, V., Novati, R., and Oriani, R.
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cross-sectional ,knowledge ,Psychometrics ,Factor structure ,nursing student ,Settore MED/44 - MEDICINA DEL LAVORO ,Nursing ,prevention ,Surveys and Questionnaires ,Content validity ,needlestick ,Medicine ,Health belief model ,Humans ,sharps injurie ,Psychometric testing ,Needlestick Injuries ,General Nursing ,Research Articles ,nursing students ,lcsh:RT1-120 ,validation ,lcsh:Nursing ,business.industry ,Injury epidemiology ,questionnaire ,sharps injuries ,Discriminant validity ,Exploratory factor analysis ,Cross-Sectional Studies ,Scale (social sciences) ,Students, Nursing ,cross‐sectional ,business ,Health Belief Model ,Research Article - Abstract
© 2020 The Authors. Nursing Open published by John Wiley & Sons Ltd. Aim: To develop an instrument to investigate knowledge and predictive factors of needlestick and sharps injuries (NSIs) in nursing students during clinical placements. Design: Instrument development and cross-sectional study for psychometric testing. Methods: A self-administered instrument including demographic data, injury epidemiology and predictive factors of NSIs was developed between October 2018–January 2019. Content validity was assessed by a panel of experts. The instrument's factor structure and discriminant validity were explored using principal components analysis. The STROBE guidelines were followed. Results: Evidence of content validity was found (S-CVI 0.75; I-CVI 0.50–1.00). A three-factor structure was shown by exploratory factor analysis. Of the 238 participants, 39% had been injured at least once, of which 67.3% in the second year. Higher perceptions of “personal exposure” (4.06, SD 3.78) were reported by third-year students. Higher scores for “perceived benefits” of preventive behaviours (13.6, SD 1.46) were reported by second-year students.
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- 2020
9. Wheelchair hockey improves quality of life in people with neuromuscular disease
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Beatrice Bobba, Andrea Lizio, Jacopo Casiraghi, Emilio Albamonte, Carolina Cardella, Elena Carraro, Susanna Pozzi, Valeria A. Sansone, Christian Lunetta, Carraro E., Casiraghi J.L., Bobba B., Lizio A., Cardella C., Albamonte E., Lunetta C., Pozzi S., and Sansone V.A.
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Adult ,medicine.medical_specialty ,Neuromuscular disease ,Adolescent ,Physical Therapy, Sports Therapy and Rehabilitation ,Young Adult ,Wheelchair ,Primary outcome ,Physical ability ,Quality of life ,medicine ,Humans ,Association (psychology) ,business.industry ,Rehabilitation ,Outcome measures ,Neuromuscular Diseases ,medicine.disease ,Cross-Sectional Studies ,Neurology ,Hockey ,Wheelchairs ,Well-being ,Adaptive sports, adaptive athletes, Neuromuscular Diseases, Spinal Muscular Atrophy, Duchenne Muscular Dystrophy, quality of life, health status ,Physical therapy ,Quality of Life ,Neurology (clinical) ,business ,human activities - Abstract
BACKGROUND Participation in sports is known to have positive effects on people's health and psycho-social well-being. Recently, physical activity implications for people with disabilities have been explored, showing promising results on quality of life and self-concept. However, few studies have specifically investigated the effects of participation in adaptive sports on neuromuscular patients' quality of life. OBJECTIVE To evaluate differences in psycho-social well-being between people affected by a neuromuscular disease who play wheelchair hockey and those who do not. Individuals playing an adaptive sport would report better quality of life, higher physical self-efficacy scores and more effective coping strategies, as assessed by self-reported measures. DESIGN Cross-sectional study. SETTING Data were collected during clinical follow-ups at the NEMO Clinical Center in Milan (Italy). PARTICIPANTS A total of 25 patients affected by neuromuscular diseases, aged 18 to 40 years, participated in the study. MAIN OUTCOME MEASURES The primary outcome was to compare quality of life between groups. Secondary outcomes were the comparisons of physical self-efficacy and coping strategies through self-reported measures. RESULTS Wheelchair hockey players scored significantly higher on the Quality of Life Index (specifically on the health/functioning and psychological/spiritual sub-scales) and reported better physical self-efficacy and perceived physical ability compared to the control group (i.e., patients who do not participate in any adaptive sport), controlling for age and pathology. On the contrary, no difference was found for coping strategies between the two groups. CONCLUSIONS This study identified a significant association between participation in wheelchair hockey and improved physical and psychological well-being of people affected by neuromuscular diseases, compared to those who are not involved in adaptive sports. This article is protected by copyright. All rights reserved.
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- 2021
10. Buccal micronucleus cytome assay in primary school children: A descriptive analysis of the MAPEC_LIFE multicenter cohort study
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Andrea Festa, Milena Villarini, Roberta Codenotti, Francesco Donato, G. Palomba, Gabriele Donzelli, Camilla Furia, Donatella Feretti, Sara Levorato, Samuele Vannini, S. Bonizzoni, Marcello Guido, Licia Zagni, Valeria Romanazzi, Umberto Gelatti, Silvia Bonetta, Annalaura Carducci, Massimo Moretti, Tania Salvatori, Tiziana Schilirò, Loredana Covolo, Gaia Claudia Viviana Viola, Paolo Colombi, Elisabetta Carraro, Claudia Zani, Francesco Bagordo, A. Bonetti, Elisabetta Ceretti, Adele Idolo, Silvano Monarca, Mattia De Giorgi, Marta Gea, Giorgio Gilli, Cristina Pignata, Francesca Di Serio, Antonella De Donno, Tiziana Grassi, Cristina Fatigoni, Marco Verani, Tiziano Verri, Sara Bonetta, Alessandra Panico, Ilaria Zerbini, Villarini, M., Levorato, S., Salvatori, T., Ceretti, E., Bonetta, S., Carducci, A., Grassi, T., Vannini, S., Donato, F., Verani, M., De Donno, A., Bonizzoni, S., Bonetti, A., Moretti, M., Gelatti, U., Fatigoni, C., Monarca, S., Covolo, L., Feretti, D., Festa, A., Viola, Gcv., Zani, C., Zerbini, I., Gilli, G., Carraro, E., Schilirò, T., Pignata, C., Gea, M., Romanazzi, V., Donzelli, G., Palomba, G., Bagordo, F., De Giorgi, M., Guido, M., Idolo, A., Panico, A., Serio, F., Verri, T., Furia, C., Colombi, P., Codenotti, R., and Zagni, L.
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0301 basic medicine ,Male ,Buccal micronucleus cytome assay ,Buccal swab ,Air pollution, Buccal micronucleus cytome assay, Children, Early biological effects, MAPEC_LIFE study, Socio-economic factors, Public Health, Environmental and Occupational Health ,MAPEC_LIFE study ,Early biological effects ,Cohort Studies ,03 medical and health sciences ,Air Pollution ,Medicine ,Humans ,Child ,Children ,Air pollution ,Socio-economic factors ,Public Health, Environmental and Occupational Health ,Micronucleus Tests ,Schools ,business.industry ,Environmental and Occupational Health ,Mouth Mucosa ,Buccal administration ,Environmental Exposure ,030104 developmental biology ,Italy ,Micronucleus test ,Cohort ,Female ,Public Health ,Seasons ,Winter season ,Micronucleus ,business ,Life study ,Children, Air pollution, Socio-economic factors, Early biological effects, Buccal micronucleus cytome assay, MAPEC_LIFE study ,Demography ,Cohort study - Abstract
Background Recent data support the hypothesis that genetic damage occurring early in life during childhood can play an important role in the development of chronic diseases in adulthood, including cancer. Objectives The objective of this paper, part of the MAPEC_LIFE project, is to describe the frequency of micronuclei and meta-nuclear alterations in exfoliated buccal cells of 6–8year-old Italian children recruited in five Italian towns (i.e., Brescia, Torino, Pisa, Perugia and Lecce) with different air pollution levels. Methods About 200 children per town were recruited from primary schools. Biological samples were collected twice from the same children, in two different seasons (winter 2014-15 and late spring 2015). Cytogenetic damage was evaluated by the buccal micronucleus cytome assay. Results Overall,n = 1046 children represent the final cohort of the MAPEC_LIFE study. On the whole, the results showed a higher mean MN frequency in winter (0.42 ± 0.54‰) than late-spring (0.22 ± 0.34‰). MN frequency observed among the five Italian towns showed a trend that follows broadly the levels of air pollution in Italy: the highest MN frequency was observed in Brescia during both seasons, the lowest in Lecce (winter) and Perugia (late-spring). Conclusions To the best of our knowledge, the number of recruited children included in the analysis (n = 1046) is the highest compared to previous studies evaluating the frequency of MN in exfoliated buccal cells so far. MN frequency was associated with winter season and living in towns at various levels of air pollution, suggesting an important role of this exposure in determining early cytogenetic effects.
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- 2018
11. Investigating the role of physical education in physical activity promotion: An Italian multicenter study
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Francesca Gallè, Valeria Di Onofrio, Fabio Barbone, Giorgio Brandi, Sebastiano Calimeri, Elisabetta Carraro, Federica Carraturo, Laura Dallolio, Concetta De Meo, Mauro De Santi, Guglielmina Fantuzzi, Francesca Fortunato, Ilaria Gorrasi, Marco Guida, Daniele Ignazio La Milia, Erica Leoni, Daniela Lo Giudice, Liliana Minelli, Christian Napoli, Maria Parpinel, Cesira Pasquarella, Rosa Prato, Vincenzo Romano Spica, Carlo Signorelli, Silvio Tafuri, Federica Valeriani, Giorgio Liguori, Gallè, Francesca, Di Onofrio, Valeria, Barbone, Fabio, Brandi, Giorgio, Calimeri, Sebastiano, Carraro, Elisabetta, Carraturo, Federica, Dallolio, Laura, De Meo, Concetta, De Santi, Mauro, Fantuzzi, Guglielmina, Fortunato, Francesca, Gorrasi, Ilaria, Guida, Marco, La Milia, Daniele Ignazio, Leoni, Erica, Giudice, Daniela Lo, Minelli, Liliana, Napoli, Christian, Parpinel, Maria, Pasquarella, Cesira, Prato, Rosa, Spica, Vincenzo Romano, Signorelli, Carlo, Tafuri, Silvio, Valeriani, Federica, Liguori, Giorgio, Onofrio, Valeria Di, Lo Giudice, Daniela, Romano Spica, Vincenzo, Gallè, F., Di Onofrio, V., Barbone, F., Brandi, G., Calimeri, S., Carraro, E., Carraturo, F., Dallolio, L., De Meo, C., De Santi, M., Fantuzzi, G., Fortunato, F., Gorrasi, I., Guida, M., La Milia, D. I., Leoni, E., Lo Giudice, D., Minelli, L., Napoli, C., Parpinel, M., Pasquarella, C., Prato, R., Spica, V. R., Signorelli, C., Tafuri, S., Valeriani, F., and Liguori, G.
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Adult ,Male ,0301 basic medicine ,Exercise promotion ,medicine.medical_specialty ,Adolescent ,media_common.quotation_subject ,Physical activity ,movement sciences ,Pilot Projects ,Physical education ,Young Adult ,03 medical and health sciences ,active lifestyle promotion ,0302 clinical medicine ,Promotion (rank) ,exercise promotion ,higher secondary school ,orthopedics and sports medicine ,Surveys and Questionnaires ,exercise promotion, movement sciences, higher secondary school ,Humans ,Medicine ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,Young adult ,Exercise ,Recreation ,Curriculum ,media_common ,Physical Education, Physical Activity Promotion ,Physical Education and Training ,business.industry ,Odds ratio ,Higher secondary school ,Physical education (PE) ,Movement science ,030104 developmental biology ,Italy ,Multicenter study ,Family medicine ,Physical therapy ,physical activity promotion ,Movement Sciences ,Female ,business - Abstract
Background:Physical education (PE) can be considered an instrument for active lifestyle promotion, and PE teachers can motivate youths to continue their studies in the field of Movement Sciences (MS).Methods:To evaluate the role of PE in higher secondary school in promoting physical activity (PA) and MS careers, previous PE experiences and current PA practice were investigated in a sample of Italian freshmen enrolled in different university degree courses.Results:A total of 7033 questionnaires were completed by students from 14 universities (41.3% males, mean age 20 ± 2.76 years). Recreation seemed to be the principal aim (42.2%) pursued during PE lessons, which are based mainly on practical activities (51.7%). Of all respondents, 67.2% were satisfied with the PE received during higher secondary school, and 51.6% participated in extracurricular PA. Current practice of PA was reported by 58.1% of the sample. Extracurricular activities were associated with choice of MS curricula (odds ratio: 2.15; 95% confidence interval, 1.85–2.50) and with current practice of PA (odds ratio: 1.68, 95% confidence interval, 1.51–1.87). Geographical differences concerning lessons organization and satisfaction were registered (P < .01).Conclusions:To enhance its role in health promotion, PE teaching should be improved by increasing the time allocated to PE and by strengthening the provision of school-based extracurricular PA.
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- 2016
12. DNA Damage in A549 Cells Exposed to Different Extracts of PM2.5 from Industrial, Urban and Highway Sites
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Elisabetta Carraro, Si. Bonetta, Sa. Bonetta, Maria Carla Gennaro, Valentina Gianotti, M Oddone, Fabio Gosetti, Bonetta, S, Gianotti, V, Gosetti, F, Oddone, M, Gennaro, M, and Carraro, E
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Environmental Engineering ,PM ,DNA damage ,Health, Toxicology and Mutagenesis ,Mutagen ,medicine.disease_cause ,Cell Line ,CHIM/01 - CHIMICA ANALITICA ,Oxidative damage ,medicine ,Humans ,Industry ,Environmental Chemistry ,Ecotoxicology ,Particle Size ,Polycyclic Aromatic Hydrocarbons ,Chemical composition ,Comet assay ,Air Pollutants ,Persistent organic pollutant ,Chemistry ,PM, Genotoxicity, Oxidative damage, Comet assay, PAH, Metals ,Public Health, Environmental and Occupational Health ,General Medicine ,General Chemistry ,PAH ,Pollution ,Genotoxicity ,Metals ,Oxidative Stress ,Environmental chemistry ,Particulate Matter ,Oxidative stress ,DNA Damage ,Environmental Monitoring - Abstract
The aim of this research is to investigate the role played by the chemical fraction of PM(2.5) in the DNA damage induction in human lung cells (A549): in particular the effects of samples collected in urban, industrial and highway sites were compared. Organic and water-soluble extracts of PM(2.5) were analysed to quantify PAHs (by GC-MS technique) and metals (by ICP-MS technique) and tested on A549 cells to evaluate, by the Comet assay (without and with Fpg enzyme), genotoxic and oxidative damage. The chemical analysis showed a variability of PAH composition in PM organic extracts of the three different sites and pointed out the presence of 14 metals (being Fe, Cu, Zn, Sb and Ba the most abundant) in all the PM water extracts. Regarding the biological effect, all the PM(2.5) organic extracts caused a significant dose-dependent increase of the A549 DNA damage. The genotoxic effect was related to the PM(2.5) PAH content and the highest effect was observed for the highway site sample. The DNA oxidative damages were observed for the PM(2.5) water extracts of the samples collected in industrial and highway sites. The extent of the oxidative damage seems to be related to the kind and concentration of the metals present. The results of this study emphasize the importance of PM chemical composition on the biological effects and highlight the need, when evaluating the effects on health and exposure management, to always consider, beside size and concentration of PM, also their qualitative composition.
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- 2009
13. UPPER LIMB REHABILITATION ROBOTICS AFTER STROKE: A PERSPECTIVE FROM THE UNIVERSITY OF PADUA, ITALY
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Claudio Ferraro, Aldo Rossi, Stefano Masiero, Giulio Rosati, Paolo Gallina, Elena Carraro, Masiero, S., Carraro, E., Ferraro, E., Gallina, Paolo, Rossi, A., and Rosati, G.
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medicine.medical_specialty ,Activities of daily living ,medicine.medical_treatment ,Physical Therapy, Sports Therapy and Rehabilitation ,rehabilitation robotics ,Motor Activity ,rehabilitation ,Upper Extremity ,Physical medicine and rehabilitation ,medicine ,Humans ,Rehabilitation robotics ,Stroke ,Rehabilitation ,Evidence-Based Medicine ,business.industry ,Perspective (graphical) ,robot ,Stroke Rehabilitation ,stroke ,Robotics ,General Medicine ,Evidence-based medicine ,Recovery of Function ,medicine.disease ,body regions ,Clinical trial ,Treatment Outcome ,Physical therapy ,Artificial intelligence ,business ,Psychology - Abstract
Rehabilitation robotics is an emerging research field that aims to employ leading-edge robotic technology and virtual reality systems in the rehabilitation treatment of neuro-logical patients. In post-stroke patients with upper limb impairment, clinical trials have so far shown positive results in terms of motor recovery, but poor efficacy in terms of functional outcome. Much work is needed to develop a new generation of rehabilitation robots and clinical protocols that will be more effective in helping patients to regain their abilities in activities of daily living. This paper presents some key issues in the future perspective of upper limb robotic rehabilitation after stroke.
- Published
- 2009
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