1. Language Development in Sex Chromosome Trisomies: Developmental Profiles at 2 and 4 Years of Age, and Predictive Measures
- Author
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Elena Capelli, Gaia Silibello, Paola Francesca Ajmone, Elena Altamore, Faustina Lalatta, Paola Giovanna Vizziello, Maria Antonella Costantino, Laura Zampini, Capelli, E, Silibello, G, Ajmone, P, Altamore, E, Lalatta, F, Vizziello, P, Costantino, M, and Zampini, L
- Subjects
Language Tests ,Sex Chromosomes ,Rehabilitation ,longitudinal study ,Trisomy ,General Medicine ,Developmental Neuroscience ,Pediatrics, Perinatology and Child Health ,predictive measure ,Humans ,Speech ,Child ,Sex chromosome trisomie ,language development - Abstract
Purpose: Describing language development in children with sex chromosome trisomies (SCT) and testing the predictive value of early language measures on later outcomes. Method: Thirteen children with SCT were followed longitudinally. Their developmental profile was assessed, with particular attention to language, at 2 and 4years. The predictive value of direct (spontaneous speech analysis) and indirect (communicative development inventory) language measures at 2 on performances at 4 was tested. Results: Language performances at both ages were lower than non-verbal development. At 2, more than 50% of the group produced less than 50 words. At 4, impaired performances were observed in speech sound development and expressive morpho-syntax. Direct measures of Pre-syntactic development predicted later global language outcomes and Sentence Repetition. The number of consonants used at 2 was significantly related to Nonword Repetition at 4. Conclusions: The study highlights the importance of early detection and careful follow-up for children with SCT.
- Published
- 2022