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Your search keyword '"Capriotti, Vincenzo"' showing total 3 results
Start Over Author "Capriotti, Vincenzo" Topic human papillomavirus
3 results on '"Capriotti, Vincenzo"'

2. HPV impact on oropharyngeal cancer radiological staging: 7th vs 8th edition of AJCC TNM classification

Author

Dal Cin, Elisa, Marcuzzo, Alberto Vito, Degrassi, Ferruccio, Volo, Tiziana, Spinato, Roberto, Politi, Doriano, Capriotti, Vincenzo, Boscolo-Rizzo, Paolo, Tirelli, Giancarlo, Dal Cin, Elisa, Marcuzzo, Alberto Vito, Degrassi, Ferruccio, Volo, Tiziana, Spinato, Roberto, Politi, Doriano, Capriotti, Vincenzo, Boscolo-Rizzo, Paolo, and Tirelli, Giancarlo

Subjects
Human papillomavirus, Oropharyngeal cancer, Head and neck cancer, Radiological staging, TNM staging, Papillomavirus Infections, Prognosis, Oropharyngeal Neoplasms, Human papillomaviru, Humans, Radiology, Nuclear Medicine and imaging, Lymph Nodes, Neoplasm Staging, Retrospective Studies
Abstract

Purpose: To evaluate the agreement between pathological and radiological staging in oropharyngeal cancer by comparing the 7th and the 8th edition of the AJCC TNM system. Methods: This retrospective cohort study included 57 cases of oropharyngeal cancer with lymph node metastases staged with the 7th and 8th editions of the AJCC TNM system. Comparison between clinical and radiological features and differences in agreement rates were calculated between radiological and pathological staging for the primary tumor (T) and lymph nodes (N) in HPVpos and HPVneg cases. Results: Comparison of HPVpos and HPVneg revealed a significantly different distribution between early and advanced stages in the 8 th edition, with a relevant number of HPVpos patients redefined from advanced stages whit the 7 th ed. to early stages with 8 th ed. (p < 0.01); no significant differences were found when comparing all diagnostic methods for T and N. Conclusions: The 8th edition of the AJCC TNM seems to lead to better pretreatment staging. For both HPVpos and HPVneg, the agreement between pretreatment radiological and pathological staging.

Published
2023
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3. Human papillomavirus infection and non-oropharyngeal head and neck cancers: an umbrella review of meta-analysis.

Author

Petrelli, Fausto, Cin, Elisa Dal, Ghidini, Antonio, Carioli, Daniela, Falasca, Vincenzo, De Stefani, Agostina, Moleri, Giovanna, Ardito, Raffaele, Luciani, Andrea, Nardone, Massimiliano, and Capriotti, Vincenzo

Subjects
HUMAN papillomavirus, HEAD & neck cancer, PAPILLOMAVIRUS diseases, NASOPHARYNX cancer, SQUAMOUS cell carcinoma
Abstract

Objective: The causative and prognostic roles of human papillomavirus (HPV) in non-oropharyngeal squamous cell carcinoma of the head and neck are uncertain. This umbrella review assessed the strength and quality of evidence and graded the evidence derived from published meta-analyses on this subject. Data sources: MEDLINE, Embase, and the Cochrane Library were searched. Meta-analyses of observational studies and randomized trials were included. Review methods: Evidence of association was graded according to the established criteria: strong, highly suggestive, suggestive, weak, or not significant. Results: 15 meta-analyses were evaluated. The association with HPV was highly suggestive of oral (OR = 2.40, [1.87–3.07], P < 0.00001) and nasopharyngeal cancers (OR = 17.82 [11.20–28.35], P < 0.00001). Improved survival emerged only in hypopharyngeal carcinoma and was confirmed in studies in which only p16 + cancers were considered. Conclusion: HPV infection may increase the risk of oral cavity and nasopharyngeal cancer. However, the prognosis was not influenced, except in hypopharyngeal carcinoma. [ABSTRACT FROM AUTHOR]

Published
2023
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