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2. Cardiorespiratory fitness in males, and upper limbs muscular strength in females, are positively related with 25-hydroxyvitamin D plasma concentrations in European adolescents: the HELENA study

Author

Valtueña Santamaría, J., Gracia Marco, L., Huybrechts, I., Breidenassel, C., Ferrari, M., Gottrand, F., Dallongeville, J., Sioen, I., Gutierrez, A., Kersting, M., Kafatos, A., Manios, Y., Widhalm, K., Moreno, L. A., González Gross, M., Moreno LA, Gottrand F, De Henauw S, González Gross M, Gilbert C, Kafatos A, Libersa C, Sáchez J, Kesting M, Sjostrom M, Molnár D, Dallongeville J, Hall G, Maes L, Scalfi L, Meléndez P, Fleta J, Casajús JA, Rodríguez G, Tomás C, Mesana MI, Vicente Rodríguez G, Villarroya A, Gil CM, Ara I, Revenga J, Lachen C, Alvira JF, Bueno G, Lázaro A, Bueno O, León JF, Garagorri JM, Bueno M, López JP, Iglesia I, Velasco P, Bel S, Gracia Marco L, Mouratidou T, Marcos A, Wärnberg J, Nova E, Gómez S, Díaz EL, Romeo J, Veses A, Puertollano MA, Zapatera B, Pozo T, Beghin L, Iliescu C, Von Berlepsch J, Kersting M, Sichert Hellert W, Koeppen E, Molnar D, Erhardt E, Csernus K, Török K, Bokor S, Nagy E, Kovács O, Repásy J, Codrington C, Plada M, Papadaki A, Sarri K, Viskadourou A, Hatzis C, Kiriakakis M, Tsibinos G, Vardavas C, Sbokos M, Protoyeraki E, Fasoulaki M, Stehle P, Pietrzik K, Breidenassel C, Spinneker A, Al Tahan J, Segoviano M, Berchtold A, Bierschbach C, Blatzheim E, Schuch A, Pickert P, Castillo MJ, Gutiérrez Á, Ortega FB, Ruiz JR, Artero EG, España Romero V, Jiménez Pavón D, Chillón P, Arcella D, Azzini E, Barrison E, Bevilacqua N, Buonocore P, Catasta G, Censi L, Ciarapica D, D' Acapito P, Ferrari M, Galfo M, Donne CL, Leclercq C, Maiani G, Mauro B, Mistura L, Pasquali A, Piccinelli R, Polito A, Spada R, Sette S, Zaccaria M, Montagnese C, De Bourdeaudhuij I, De Vriendt T, Matthys C, Vereecken C, de Maeyer M, Ottevaere C, Huybrechts I, Widhalm K, Phillipp K, Dietrich S, Manios Y, Grammatikaki E, Bouloubasi Z, Cook TL, Eleutheriou S, Consta O, Moschonis G, Katsaroli I, Kraniou G, Papoutsou S, Keke D, Petraki I, Bellou E, Tanagra S, Kallianoti K, Argyropoulou D, Kondaki K, Tsikrika S, Karaiskos C, Meirhaeghe A, Sjöstrom M, Bergman P, Hagströmer M, Hallström L, Hallberg M, Poortvliet E, Rizzo N, Beckman L, Wennlöf AH, Patterson E, Kwak L, Cernerud L, Tillgren P, Sörensen S, Sánchez Molero J, Picó E, Navarro M, Viadel B, Carreres JE, Merino G, Sanjuán R, Lorente M, Sánchez MJ, Castelló S, Thomas S, Allchurch E, Burguess P, Astrom A, Sverkén A, Broberg A, Masson A, Lehoux C, Brabant P, Pate P, Fontaine L, Sebok A, Kuti T, Hegyi A, Maldonado C, Llorente A, García E, von Fircks H, Hallberg ML, Messerer M, Larsson M, Fredriksson H, Adamsson V, Börjesson I, Fernández L, Smillie L, Wills J, Valtueña J, Albers U, Pedrero R, Meléndez A, Benito PJ, Lorente JJ, Cañada D, Urzanqui A, Ortiz JC, Fuentes F, Torres RM, Navarro P., VITAGLIONE, PAOLA, Valtueña Santamaría, J., Gracia Marco, L., Huybrechts, I., Breidenassel, C., Ferrari, M., Gottrand, F., Dallongeville, J., Sioen, I., Gutierrez, A., Kersting, M., Kafatos, A., Manios, Y., Widhalm, K., Moreno, L. A., González Gross, M., Moreno, La, Gottrand, F, De Henauw, S, González Gross, M, Gilbert, C, Kafatos, A, Libersa, C, Sáchez, J, Kesting, M, Sjostrom, M, Molnár, D, Dallongeville, J, Hall, G, Maes, L, Scalfi, L, Meléndez, P, Fleta, J, Casajús, Ja, Rodríguez, G, Tomás, C, Mesana, Mi, Vicente Rodríguez, G, Villarroya, A, Gil, Cm, Ara, I, Revenga, J, Lachen, C, Alvira, Jf, Bueno, G, Lázaro, A, Bueno, O, León, Jf, Garagorri, Jm, Bueno, M, López, Jp, Iglesia, I, Velasco, P, Bel, S, Gracia Marco, L, Mouratidou, T, Marcos, A, Wärnberg, J, Nova, E, Gómez, S, Díaz, El, Romeo, J, Veses, A, Puertollano, Ma, Zapatera, B, Pozo, T, Beghin, L, Iliescu, C, Von Berlepsch, J, Kersting, M, Sichert Hellert, W, Koeppen, E, Molnar, D, Erhardt, E, Csernus, K, Török, K, Bokor, S, Nagy, E, Kovács, O, Repásy, J, Codrington, C, Plada, M, Papadaki, A, Sarri, K, Viskadourou, A, Hatzis, C, Kiriakakis, M, Tsibinos, G, Vardavas, C, Sbokos, M, Protoyeraki, E, Fasoulaki, M, Stehle, P, Pietrzik, K, Breidenassel, C, Spinneker, A, Al Tahan, J, Segoviano, M, Berchtold, A, Bierschbach, C, Blatzheim, E, Schuch, A, Pickert, P, Castillo, Mj, Gutiérrez, Á, Ortega, Fb, Ruiz, Jr, Artero, Eg, España Romero, V, Jiménez Pavón, D, Chillón, P, Arcella, D, Azzini, E, Barrison, E, Bevilacqua, N, Buonocore, P, Catasta, G, Censi, L, Ciarapica, D, D' Acapito, P, Ferrari, M, Galfo, M, Donne, Cl, Leclercq, C, Maiani, G, Mauro, B, Mistura, L, Pasquali, A, Piccinelli, R, Polito, A, Spada, R, Sette, S, Zaccaria, M, Vitaglione, Paola, Montagnese, C, De Bourdeaudhuij, I, De Vriendt, T, Matthys, C, Vereecken, C, de Maeyer, M, Ottevaere, C, Huybrechts, I, Widhalm, K, Phillipp, K, Dietrich, S, Manios, Y, Grammatikaki, E, Bouloubasi, Z, Cook, Tl, Eleutheriou, S, Consta, O, Moschonis, G, Katsaroli, I, Kraniou, G, Papoutsou, S, Keke, D, Petraki, I, Bellou, E, Tanagra, S, Kallianoti, K, Argyropoulou, D, Kondaki, K, Tsikrika, S, Karaiskos, C, Meirhaeghe, A, Sjöstrom, M, Bergman, P, Hagströmer, M, Hallström, L, Hallberg, M, Poortvliet, E, Rizzo, N, Beckman, L, Wennlöf, Ah, Patterson, E, Kwak, L, Cernerud, L, Tillgren, P, Sörensen, S, Sánchez Molero, J, Picó, E, Navarro, M, Viadel, B, Carreres, Je, Merino, G, Sanjuán, R, Lorente, M, Sánchez, Mj, Castelló, S, Thomas, S, Allchurch, E, Burguess, P, Astrom, A, Sverkén, A, Broberg, A, Masson, A, Lehoux, C, Brabant, P, Pate, P, Fontaine, L, Sebok, A, Kuti, T, Hegyi, A, Maldonado, C, Llorente, A, García, E, von Fircks, H, Hallberg, Ml, Messerer, M, Larsson, M, Fredriksson, H, Adamsson, V, Börjesson, I, Fernández, L, Smillie, L, Wills, J, Valtueña, J, Albers, U, Pedrero, R, Meléndez, A, Benito, Pj, Lorente, Jj, Cañada, D, Urzanqui, A, Ortiz, Jc, Fuentes, F, Torres, Rm, and Navarro, P.

Subjects
Male, medicine.medical_specialty, Adolescent, European Continental Ancestry Group, Physical fitness, Physical strength, White People, vitamin D deficiency, Upper Extremity, Cardiovascular Disease, Internal medicine, medicine, Vitamin D and neurology, Humans, Muscle Strength, Vitamin D, Adiposity, Cross-Sectional Studie, business.industry, Medicine (all), VO2 max, Cardiorespiratory fitness, General Medicine, Vitamin D Deficiency, medicine.disease, Obesity, Europe, Cross-Sectional Studies, Endocrinology, Cardiovascular Diseases, Physical Fitness, Physical Fitne, Body Composition, Exercise Test, Female, business, Body mass index, Human
Abstract

Background: High prevalence of vitamin D insufficiency (

Published
2013

3. Vitamin D status and physical activity interact to improve bone mass in adolescents. The HELENA Study

Author

Valtuena, J., Gracia Marco, L., Vicente Rodríguez, G., González Gross, M., Huybrechts, I., Rey López, J. P., Mouratidou, T., Sioen, I., Mesana, M. I., Díaz Martínez, A. E., Widhalm, K., Moreno, L. A., Moreno LA, Gottrand F, De Henauw S, González Gross M, Gilbert C, Kafatos A, Libersa C, Sáchez J, Kesting M, Sjostrom M, Molnár D, Dallongeville J, Hall G, Maes L, Scalfi L, Meléndez P, Fleta J, Casajús JA, Rodríguez G, Tomás C, Mesana MI, Vicente Rodríguez G, Villarroya A, Gil CM, Ara I, Revenga J, Lachen C, Fernández Alvira J, Bueno G, Lázaro A, Bueno O, León JF, Garagorri JM, Bueno M, López JP, Iglesia I, Velasco P, Bel S, Mouratidou T, Marcos A, Wärnberg J, Nova E, Gómez S, Díaz EL, Romeo J, Veses A, Puertollano MA, Zapatera B, Pozo T, Beghin L, Iliescu C, Von Berlepsch J, Kersting M, Sichert Hellert W, Koeppen E, Molnar D, Erhardt E, Csernus K, Török K, Bokor S, Angster, Nagy E, Kovács O, Repásy J, Codrington C, Plada M, Papadaki A, Sarri K, Viskadourou A, Hatzis C, Kiriakakis M, Tsibinos G, Sbokos CV, Protoyeraki E, Fasoulaki M, Stehle P, Pietrzik K, Breidenassel C, Spinneker A, Al Tahan J, Segoviano M, Berchtold A, Bierschbach C, Blatzheim E, Schuch A, Pickert P, Castillo MJ, Gutiérrez Á, Ortega FB, Ruiz JR, Artero EG, España Romero V, Jiménez Pavón D, Chillón P, Arcella D, Azzini E, Barrison E, Bevilacqua N, Buonocore P, Catasta G, Censi L, Ciarapica D, D'Acapito P, Ferrari M, Galfo M, Le Donne C, Leclercq C, Maiani G, Mauro B, Mistura L, Pasquali A, Piccinelli R, Polito A, Spada R, Sette S, Zaccaria M, Montagnese C, De Bourdeaudhuij I, De Vriendt T, Matthys C, Vereecken C, de Maeyer M, Ottevaere C, Huybrechts I, Widhalm K, Phillipp K, Dietrich S, Manios Y, Grammatikaki E, Bouloubasi Z, Cook TL, Eleutheriou S, Consta O, Moschonis G, Katsaroli I, Kraniou G, Papoutsou S, Keke D, Petraki I, Bellou E, Tanagra S, Kallianoti K, Argyropoulou D, Kondaki K, Tsikrika S, Karaiskos C, Meirhaeghe A, Sjöstrom M, Bergman P, Hagströmer M, Hallström L, Hallberg M, Poortvliet E, Rizzo N, Beckman L, HurtigWennlöf A, Patterson E, Kwak L, Cernerud L, Tillgren P, Sörensen S, Sánchez Molero J, Picó E, Navarro M, Viadel B, Carreres JE, Merino G, Sanjuán R, Lorente M, Sánchez MJ, Castelló S, Thomas S, Allchurch E, Burguess P, Astrom A, Sverkén A, Broberg A, Masson A, Lehoux C, Brabant P, Pate P, Fontaine L, Sebok A, Kuti T, Hegyi A, Maldonado C, Llorente A, García E, von Fircks H, Hallberg ML, Messerer M, Larsson M, Fredriksson H, Adamsson V, Börjesson I, Fernández L, Smillie L, Wills J, Valtueña J, Albers U, Pedrero R, Meléndez A, Benito PJ, Gómez Lorente JJ, Cañada D, Urzanqui A, Ortiz JC, Fuentes F, Torres RM, Navarro P., VITAGLIONE, PAOLA, Valtuena, J., Gracia Marco, L., Vicente Rodríguez, G., González Gross, M., Huybrechts, I., Rey López, J. P., Mouratidou, T., Sioen, I., Mesana, M. I., Díaz Martínez, A. E., Widhalm, K., Moreno, L. A., Moreno, La, Gottrand, F, De Henauw, S, González Gross, M, Gilbert, C, Kafatos, A, Libersa, C, Sáchez, J, Kesting, M, Sjostrom, M, Molnár, D, Dallongeville, J, Hall, G, Maes, L, Scalfi, L, Meléndez, P, Fleta, J, Casajús, Ja, Rodríguez, G, Tomás, C, Mesana, Mi, Vicente Rodríguez, G, Villarroya, A, Gil, Cm, Ara, I, Revenga, J, Lachen, C, Fernández Alvira, J, Bueno, G, Lázaro, A, Bueno, O, León, Jf, Garagorri, Jm, Bueno, M, López, Jp, Iglesia, I, Velasco, P, Bel, S, Mouratidou, T, Marcos, A, Wärnberg, J, Nova, E, Gómez, S, Díaz, El, Romeo, J, Veses, A, Puertollano, Ma, Zapatera, B, Pozo, T, Beghin, L, Iliescu, C, Von Berlepsch, J, Kersting, M, Sichert Hellert, W, Koeppen, E, Molnar, D, Erhardt, E, Csernus, K, Török, K, Bokor, S, Angster, Nagy, E, Kovács, O, Repásy, J, Codrington, C, Plada, M, Papadaki, A, Sarri, K, Viskadourou, A, Hatzis, C, Kiriakakis, M, Tsibinos, G, Sbokos, Cv, Protoyeraki, E, Fasoulaki, M, Stehle, P, Pietrzik, K, Breidenassel, C, Spinneker, A, Al Tahan, J, Segoviano, M, Berchtold, A, Bierschbach, C, Blatzheim, E, Schuch, A, Pickert, P, Castillo, Mj, Gutiérrez, Á, Ortega, Fb, Ruiz, Jr, Artero, Eg, España Romero, V, Jiménez Pavón, D, Chillón, P, Arcella, D, Azzini, E, Barrison, E, Bevilacqua, N, Buonocore, P, Catasta, G, Censi, L, Ciarapica, D, D'Acapito, P, Ferrari, M, Galfo, M, Le Donne, C, Leclercq, C, Maiani, G, Mauro, B, Mistura, L, Pasquali, A, Piccinelli, R, Polito, A, Spada, R, Sette, S, Zaccaria, M, Vitaglione, Paola, Montagnese, C, De Bourdeaudhuij, I, De Vriendt, T, Matthys, C, Vereecken, C, de Maeyer, M, Ottevaere, C, Huybrechts, I, Widhalm, K, Phillipp, K, Dietrich, S, Manios, Y, Grammatikaki, E, Bouloubasi, Z, Cook, Tl, Eleutheriou, S, Consta, O, Moschonis, G, Katsaroli, I, Kraniou, G, Papoutsou, S, Keke, D, Petraki, I, Bellou, E, Tanagra, S, Kallianoti, K, Argyropoulou, D, Kondaki, K, Tsikrika, S, Karaiskos, C, Meirhaeghe, A, Sjöstrom, M, Bergman, P, Hagströmer, M, Hallström, L, Hallberg, M, Poortvliet, E, Rizzo, N, Beckman, L, Hurtigwennlöf, A, Patterson, E, Kwak, L, Cernerud, L, Tillgren, P, Sörensen, S, Sánchez Molero, J, Picó, E, Navarro, M, Viadel, B, Carreres, Je, Merino, G, Sanjuán, R, Lorente, M, Sánchez, Mj, Castelló, S, Thomas, S, Allchurch, E, Burguess, P, Astrom, A, Sverkén, A, Broberg, A, Masson, A, Lehoux, C, Brabant, P, Pate, P, Fontaine, L, Sebok, A, Kuti, T, Hegyi, A, Maldonado, C, Llorente, A, García, E, von Fircks, H, Hallberg, Ml, Messerer, M, Larsson, M, Fredriksson, H, Adamsson, V, Börjesson, I, Fernández, L, Smillie, L, Wills, J, Valtueña, J, Albers, U, Pedrero, R, Meléndez, A, Benito, Pj, Gómez Lorente, Jj, Cañada, D, Urzanqui, A, Ortiz, Jc, Fuentes, F, Torres, Rm, and Navarro, P.

Subjects
Male, musculoskeletal diseases, medicine.medical_specialty, Adolescent, Adolescent Nutritional Physiological Phenomena, Endocrinology, Diabetes and Metabolism, Physical fitness, Physical activity, chemistry.chemical_element, Motor Activity, Calcium, Bone and Bones, Absorptiometry, Photon, Bone Density, Risk Factors, Surveys and Questionnaires, Internal medicine, medicine, Vitamin D and neurology, Surveys and Questionnaire, Humans, Body Weights and Measures, Vitamin D, Bone, Child, Calcifediol, Cross-Sectional Studie, business.industry, Risk Factor, Body Weights and Measure, Physical fitne, Anthropometry, humanities, Cross-Sectional Studies, Endocrinology, chemistry, Body Composition, Lean body mass, Bone mineral content, Female, Season, Seasons, business, human activities, Bone and Bone, Human, Bone mass
Abstract

The effects of vitamin D concentrations on bone mineral content in adolescents are still unclear. Vitamin D and physical activity (PA) may interact to determine bone mineral content (BMC) in two possible directions; 25(OH)D sufficiency levels improve BMC only in active adolescents, or PA increases BMC in individuals with replete vitamin D levels. The effects of suboptimal 25-hydroxycholecalciferol (25(OH)D) concentrations on BMC in adolescents are still unclear. The main aim of this study was to evaluate the influence of 25(OH)D on BMC in adolescents, considering the effect of body composition, sex, age, Tanner stage, season, calcium and vitamin D intakes, physical fitness and PA. Serum 25(OH)D concentrations, anthropometric measurements, dual energy X-ray absorptiometry measurements, calcium and vitamin D intakes, PA and physical fitness were obtained in 100 Spanish adolescents (47 males), aged 12.5–17.5 years, within the framework of the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study. Relations were examined using ANCOVA and regression analyses including BMC as dependent variable. Linear regression of BMC suggested that 25(OH)D concentrations independently influenced total and leg BMC after controlling for age, sex, lean mass, seasonality and calcium intake (B = 0.328, p

Published
2012

4. Inflammation profile in overweight/obese adolescents in Europe: an analysis in relation to iron status

Author

Ferrari, M, Cuenca García, M., Valtueña, J., Moreno, L. A., Censi, L., González Gross, M., Androutsos, O., Gilbert, C. C., Huybrechts, I., Dallongeville, J., Sjöström, M., Molnar, D., De Henauw, S., Gómez Martínez, S., De Moraes, A. C. F., Kafatos, A., Widhalm, K., Leclercq, C., Moreno LA, Gottrand F, De Henauw S, González Gross M, Gilbert C, Kafatos A, Libersa C, Sáchez J, Kesting M, Sjostrom M, Molnár D, Dallongeville J, Hall G, Maes L, Scalfi L, Meléndez P, Fleta J, Casajús JA, Rodríguez G, Tomás C, Mesana MI, Vicente Rodríguez G, Villarroya A, Gil CM, Ara I, Revenga J, Lachen C, Fernández Alvira J, Bueno G, Aurora Lázaro, Bueno O, León JF, Garagorri JM, Bueno M, López JP, Iglesia I, Velasco P, Bel S, Marcos A, Wärnberg J, Nova E, Gómez S, Díaz EL, Romeo J, Veses A, Puertollano MA, Zapatera B, Pozo T, Beghin L, Iliescu C, Von Berlepsch J, Kersting M, Sichert Hellert W, Koeppen E, Molnar D, Erhardt E, Csernus K, Török K, Bokor S, Nagy E, Kovács O, Repásy J, Codrington C, Plada M, Papadaki A, Sarri K, Viskadourou A, Hatzis C, Kiriakakis M, Tsibinos G, Sbokos CV, Protoyeraki E, Fasoulaki M, Stehle P, Pietrzik K, Breidenassel C, Spinneker A, Al Tahan J, Segoviano M, Berchtold A, Bierschbach C, Blatzheim E, Schuch A, Picker P, Castillo MJ, Gutiérrez Á, Ortega FB, Ruiz JR, Artero EG, España Romero V, Jiménez Pavón D, Chillón P, Cuenca Garcia M, Arcella D, Azzini E, Barrison E, Bevilacqua N, Buonocore P, Catasta G, Censi L, Ciarapica D, D'Acapito P, Ferrari M, Galfo M, Donne CL, Leclercq C, Maiani G, Mauro B, Mistura L, Pasquali A, Piccinelli R, Polito A, Spada R, Sette S, Zaccaria M, Montagnese C, De Vriendt T, Matthys C, Vereecken C, de Maeyer M, Ottevaere C, Huybrechts I, Widhalm K, Phillipp K, Dietrich S, Manios Y, Grammatikaki E, Bouloubasi Z, Cook TL, Consta O, Moschonis G, Katsaroli I, Kraniou G, Papoutsou S, Keke D, Petraki I, Bellou E, Tanagra S, Kallianoti K, Argyropoulou D, Kondaki K, Tsikrika S, Karaiskos C, Meirhaeghe A, Sjöstrom M, Bergman P, Hagströmer M, Hallström L, Hallberg M, Poortvliet E, Rizzo N, Beckman L, Wennlöf AH, Patterson E, Kwak L, Cernerud L, Tillgren P, Sörensen S, Sánchez Molero J, Picó E, Navarro M, Viadel B, Carreres JE, Merino G, Sanjuán R, Lorente M, Sánchez MJ, Thomas S, Allchurch E, Burgess P, Astrom A, Sverkén A, Broberg A, Masson A, Lehoux C, Brabant P, Pate P, Fontaine L, Sebok A, Kuti T, Hegyi A, Maldonado C, Llorente A, García E, von Fircks H, Hallberg ML, Messerer M, Larsson M, Fredriksson H, Adamsson V, Börjesson I, Fernández L, Smillie L, Wills J, Valtueña J, Albers U, Pedrero R, Meléndez A, Benito PJ, Gómez Lorente JJ, Cañada D, Urzanqui A, Ortiz JC, Fuentes F, Torres RM, Navarro P., VITAGLIONE, PAOLA, European Commission, Ministerio de Educación (España), Universidad Politécnica de Madrid, Sao Paulo Research Foundation, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil), Conselho Nacional de Desenvolvimento Científico e Tecnológico (Brasil), Ferrari, M, Cuenca García, M., Valtueña, J., Moreno, L. A., Censi, L., González Gross, M., Androutsos, O., Gilbert, C. C., Huybrechts, I., Dallongeville, J., Sjöström, M., Molnar, D., De Henauw, S., Gómez Martínez, S., De Moraes, A. C. F., Kafatos, A., Widhalm, K., Leclercq, C., Moreno, La, Gottrand, F, De Henauw, S, González Gross, M, Gilbert, C, Kafatos, A, Libersa, C, Sáchez, J, Kesting, M, Sjostrom, M, Molnár, D, Dallongeville, J, Hall, G, Maes, L, Scalfi, L, Meléndez, P, Fleta, J, Casajús, Ja, Rodríguez, G, Tomás, C, Mesana, Mi, Vicente Rodríguez, G, Villarroya, A, Gil, Cm, Ara, I, Revenga, J, Lachen, C, Fernández Alvira, J, Bueno, G, Aurora, Lázaro, Bueno, O, León, Jf, Garagorri, Jm, Bueno, M, López, Jp, Iglesia, I, Velasco, P, Bel, S, Marcos, A, Wärnberg, J, Nova, E, Gómez, S, Díaz, El, Romeo, J, Veses, A, Puertollano, Ma, Zapatera, B, Pozo, T, Beghin, L, Iliescu, C, Von Berlepsch, J, Kersting, M, Sichert Hellert, W, Koeppen, E, Molnar, D, Erhardt, E, Csernus, K, Török, K, Bokor, S, Nagy, E, Kovács, O, Repásy, J, Codrington, C, Plada, M, Papadaki, A, Sarri, K, Viskadourou, A, Hatzis, C, Kiriakakis, M, Tsibinos, G, Sbokos, Cv, Protoyeraki, E, Fasoulaki, M, Stehle, P, Pietrzik, K, Breidenassel, C, Spinneker, A, Al Tahan, J, Segoviano, M, Berchtold, A, Bierschbach, C, Blatzheim, E, Schuch, A, Picker, P, Castillo, Mj, Gutiérrez, Á, Ortega, Fb, Ruiz, Jr, Artero, Eg, España Romero, V, Jiménez Pavón, D, Chillón, P, Cuenca Garcia, M, Arcella, D, Azzini, E, Barrison, E, Bevilacqua, N, Buonocore, P, Catasta, G, Censi, L, Ciarapica, D, D'Acapito, P, Galfo, M, Donne, Cl, Leclercq, C, Maiani, G, Mauro, B, Mistura, L, Pasquali, A, Piccinelli, R, Polito, A, Spada, R, Sette, S, Zaccaria, M, Vitaglione, Paola, Montagnese, C, De Vriendt, T, Matthys, C, Vereecken, C, de Maeyer, M, Ottevaere, C, Huybrechts, I, Widhalm, K, Phillipp, K, Dietrich, S, Manios, Y, Grammatikaki, E, Bouloubasi, Z, Cook, Tl, Consta, O, Moschonis, G, Katsaroli, I, Kraniou, G, Papoutsou, S, Keke, D, Petraki, I, Bellou, E, Tanagra, S, Kallianoti, K, Argyropoulou, D, Kondaki, K, Tsikrika, S, Karaiskos, C, Meirhaeghe, A, Sjöstrom, M, Bergman, P, Hagströmer, M, Hallström, L, Hallberg, M, Poortvliet, E, Rizzo, N, Beckman, L, Wennlöf, Ah, Patterson, E, Kwak, L, Cernerud, L, Tillgren, P, Sörensen, S, Sánchez Molero, J, Picó, E, Navarro, M, Viadel, B, Carreres, Je, Merino, G, Sanjuán, R, Lorente, M, Sánchez, Mj, Thomas, S, Allchurch, E, Burgess, P, Astrom, A, Sverkén, A, Broberg, A, Masson, A, Lehoux, C, Brabant, P, Pate, P, Fontaine, L, Sebok, A, Kuti, T, Hegyi, A, Maldonado, C, Llorente, A, García, E, von Fircks, H, Hallberg, Ml, Messerer, M, Larsson, M, Fredriksson, H, Adamsson, V, Börjesson, I, Fernández, L, Smillie, L, Wills, J, Valtueña, J, Albers, U, Pedrero, R, Meléndez, A, Benito, Pj, Gómez Lorente, Jj, Cañada, D, Urzanqui, A, Ortiz, Jc, Fuentes, F, Torres, Rm, and Navarro, P.

Subjects
Male, Cross-sectional study, Medicine (miscellaneous), Sex Factor, Overweight, Body Mass Index, Nutrition and Dietetic, Adiposity, Nutrition and Dietetics, biology, Anemia, Iron-Deficiency, Medicine (all), Transferrin, Iron Deficiencies, Orosomucoid, Europe, Nutritional Statu, C-Reactive Protein, Adipose Tissue, Female, Iron status, Dietary Proteins, medicine.symptom, Human, medicine.medical_specialty, Adolescent, Iron, Nutritional Status, Inflammation, Sex Factors, Internal medicine, Environmental health, medicine, Humans, Obesity, Cross-Sectional Studie, Ferritin, business.industry, Dietary Protein, C-reactive protein, nutritional and metabolic diseases, Biomarker, Anthropometry, medicine.disease, Diet, Endocrinology, Cross-Sectional Studies, Ferritins, biology.protein, business, Body mass index, Biomarkers
Abstract

On behalf of the HELENA Study Group., [Background/Objectives]: The objectives of this study were to investigate the relationship between inflammatory parameters (CRP, c-reactive protein; AGP, α1-acid glycoprotein), iron status indicators (SF, serum ferritin; sTfR, soluble transferrin receptor) and body mass index (BMI) z-score, fat-free mass (FFM) and fat mass (FM) in European adolescents. Differences in intake for some nutrients (total iron, haem and non-haem iron, vitamin C, calcium, proteins) were assessed according to BMI categories, and the association of nutrient intakes with BMI z-score, FM and FFM was evaluated., [Methods]: A total of 876 adolescents participating in the Healthy Lifestyle in Europe by Nutrition in Adolescence-Cross Sectional Study were included in the study sample., [Results]: Mean CRP values (standard error; s.e.) were significantly higher in overweight/obese adolescents (1.7±0.3 and 1.4±0.3 mg/l in boys and girls, respectively) than in thin/normal-weight adolescents (1.1±0.2 and 1.0±0.1 mg/l in boys and girls, respectively) (P, [Conclusions]: The adiposity of the European adolescents was sufficient to cause chronic inflammation but not sufficient to impair iron status and cause iron deficiency., The HELENA Study has taken place with the financial support of the European Community Sixth RTD Framework Programme (Contract FOOD-CT-2005–007034). Additional support was obtained from the Spanish Ministry of Education (AGL2007-29784-E/ALI; AP-2005-3827; AP-2008-03806). Jara Valtueña was financially supported by the Universidad Politécnica de Madrid. Augusto César F. de Moraes was given scholarship from São Paulo Research Foundation – FAPESP (proc. 2011/11137-1 and 2011/20662-2). Luis A. Moreno was given scholarship of visiting professor from Brazilian government by Science without Borders Program by CNPq (National Counsel of Technological and Scientific Development) and CAPES (Coordination of Improvement of Higher Education Personnel) (proc. 007/2012).

Published
2015

5. Vitamin D status among adolescents in Europe: the Healthy Lifestyle in Europe by Nutrition in Adolescence study

Author

González Gross, Marcela, Valtueña, Jara, Breidenassel, Christina, Moreno, Luis A., Ferrari, Marika, Kersting, Matilde, De Henauw, Stefaan, Gottrand, Frederic, Azzini, Elena, Widhalm, Kurt, Kafatos, Anthony, Manios, Yannis, Stehle, Peter, Moreno LA, Gottrand F, De Henauw S, González Gross M, Gilbert C, Kafatos A, Libersa C, Sáchez J, Kesting M, Sjostrom M, Molnár D, Dallongeville J, Hall G, Maes L, Scalfi L, Meléndez P, Fleta J, Casajús JA, Rodríguez G, Tomás C, Mesana MI, Vicente Rodríguez G, Villarroya A, Gil CM, Ara I, Revenga J, Lachen C, Fernández Alvira J, Bueno G, Lázaro A, Bueno O, León JF, Ma Garagorri J, Bueno M, Rey López JP, Iglesia I, Velasco P, Bel S, Marcos A, Wärnberg J, Nova E, Gómez S, Ligia Díaz E, Romeo J, Veses A, Angeles Puertollano M, Zapatera B, Pozo T, Beghin L, Iliescu C, Von Berlepsch J, Kersting M, Sichert Hellert W, Koeppen E, Molnar D, Erhardt E, Csernus K, Török K, Bokor S, Angster M, Nagy E, Kovács O, Repásy J, Codrington C, Plada M, Papadaki A, Sarri K, Viskadourou A, Hatzis C, Kiriakakis M, Tsibinos G, Manolis Sbokos CV, Protoyeraki E, Fasoulaki M, Stehle P, Pietrzik K, Breidenassel C, Spinneker A, Al Tahan J, Segoviano M, Berchtold A, Bierschbach C, Blatzheim E, Schuch A, Pickert P, Castillo MJ, Gutiérrez Á, Ortega FB, Ruiz JR, Artero EG, España Romero V, Jiménez Pavón D, Chillón P, Arcella D, Azzini E, Barrison E, Bevilacqua N, Buonocore P, Catasta G, Censi L, Ciarapica D, D'Acapito P, Ferrari M, Galfo M, Le Donne C, Leclercq C, Maiani G, Mauro B, Mistura L, Pasquali A, Piccinelli R, Polito A, Spada R, Sette S, Zaccaria M, Montagnese C, De Bourdeaudhuij I, Huybrechts I, De Vriendt T, Matthys C, Vereecken C, de Maeyer M, Ottevaere C, Widhalm K, Phillipp K, Dietrich S, Boriss Riedl BK, Manios Y, Grammatikaki E, Bouloubasi Z, Cook TL, Eleutheriou S, Consta O, Moschonis G, Katsaroli I, Kraniou G, Papoutsou S, Keke D, Petraki I, Bellou E, Tanagra S, Kallianoti K, Argyropoulou D, Kondaki K, Tsikrika S, Karaiskos C, Meirhaeghe A, Sjöstrom M, Bergman P, Hagströmer M, Hallström L, Hallberg M, Poortvliet E, Rizzo N, Beckman L, Wennlöf AH, Patterson E, Kwak L, Cernerud L, Tillgren P, Sörensen S, Sánchez Molero J, Picó E, Navarro M, Viadel B, Enrique Carreres J, Merino G, Sanjuán R, Lorente M, Sánchez MJ, Castelló S, Thomas S, Allchurch E, Burguess P, Astrom A, Sverkén A, Broberg A, Masson A, Lehoux C, Brabant P, Pate P, Fontaine L, Sebok A, Kuti T, Hegyi A, Maldonado C, Llorente A, García E, von Fircks H, Hallberg ML, Messerer M, Larsson M, Fredriksson H, Adamsson V, Börjesson I, Fernández L, Smillie L, Wills J, Valtueña J, Albers U, Pedrero R, Meléndez A, Benito PJ, Gómez Lorente JJ, Cañada D, Urzanqui A, Ortiz JC, Fuentes F, Torres RM, Paloma Navarro T., VITAGLIONE, PAOLA, González Gross, Marcela, Valtueña, Jara, Breidenassel, Christina, Moreno, Luis A., Ferrari, Marika, Kersting, Matilde, De Henauw, Stefaan, Gottrand, Frederic, Azzini, Elena, Widhalm, Kurt, Kafatos, Anthony, Manios, Yanni, Stehle, Peter, Moreno, La, Gottrand, F, De Henauw, S, González Gross, M, Gilbert, C, Kafatos, A, Libersa, C, Sáchez, J, Kesting, M, Sjostrom, M, Molnár, D, Dallongeville, J, Hall, G, Maes, L, Scalfi, L, Meléndez, P, Fleta, J, Casajús, Ja, Rodríguez, G, Tomás, C, Mesana, Mi, Vicente Rodríguez, G, Villarroya, A, Gil, Cm, Ara, I, Revenga, J, Lachen, C, Fernández Alvira, J, Bueno, G, Lázaro, A, Bueno, O, León, Jf, Ma Garagorri, J, Bueno, M, Rey López, Jp, Iglesia, I, Velasco, P, Bel, S, Marcos, A, Wärnberg, J, Nova, E, Gómez, S, Ligia Díaz, E, Romeo, J, Veses, A, Angeles Puertollano, M, Zapatera, B, Pozo, T, Beghin, L, Iliescu, C, Von Berlepsch, J, Kersting, M, Sichert Hellert, W, Koeppen, E, Molnar, D, Erhardt, E, Csernus, K, Török, K, Bokor, S, Angster, M, Nagy, E, Kovács, O, Repásy, J, Codrington, C, Plada, M, Papadaki, A, Sarri, K, Viskadourou, A, Hatzis, C, Kiriakakis, M, Tsibinos, G, Manolis Sbokos, Cv, Protoyeraki, E, Fasoulaki, M, Stehle, P, Pietrzik, K, Breidenassel, C, Spinneker, A, Al Tahan, J, Segoviano, M, Berchtold, A, Bierschbach, C, Blatzheim, E, Schuch, A, Pickert, P, Castillo, Mj, Gutiérrez, Á, Ortega, Fb, Ruiz, Jr, Artero, Eg, España Romero, V, Jiménez Pavón, D, Chillón, P, Arcella, D, Azzini, E, Barrison, E, Bevilacqua, N, Buonocore, P, Catasta, G, Censi, L, Ciarapica, D, D'Acapito, P, Ferrari, M, Galfo, M, Le Donne, C, Leclercq, C, Maiani, G, Mauro, B, Mistura, L, Pasquali, A, Piccinelli, R, Polito, A, Spada, R, Sette, S, Zaccaria, M, Vitaglione, Paola, Montagnese, C, De Bourdeaudhuij, I, Huybrechts, I, De Vriendt, T, Matthys, C, Vereecken, C, de Maeyer, M, Ottevaere, C, Widhalm, K, Phillipp, K, Dietrich, S, Boriss Riedl, Bk, Manios, Y, Grammatikaki, E, Bouloubasi, Z, Cook, Tl, Eleutheriou, S, Consta, O, Moschonis, G, Katsaroli, I, Kraniou, G, Papoutsou, S, Keke, D, Petraki, I, Bellou, E, Tanagra, S, Kallianoti, K, Argyropoulou, D, Kondaki, K, Tsikrika, S, Karaiskos, C, Meirhaeghe, A, Sjöstrom, M, Bergman, P, Hagströmer, M, Hallström, L, Hallberg, M, Poortvliet, E, Rizzo, N, Beckman, L, Wennlöf, Ah, Patterson, E, Kwak, L, Cernerud, L, Tillgren, P, Sörensen, S, Sánchez Molero, J, Picó, E, Navarro, M, Viadel, B, Enrique Carreres, J, Merino, G, Sanjuán, R, Lorente, M, Sánchez, Mj, Castelló, S, Thomas, S, Allchurch, E, Burguess, P, Astrom, A, Sverkén, A, Broberg, A, Masson, A, Lehoux, C, Brabant, P, Pate, P, Fontaine, L, Sebok, A, Kuti, T, Hegyi, A, Maldonado, C, Llorente, A, García, E, von Fircks, H, Hallberg, Ml, Messerer, M, Larsson, M, Fredriksson, H, Adamsson, V, Börjesson, I, Fernández, L, Smillie, L, Wills, J, Valtueña, J, Albers, U, Pedrero, R, Meléndez, A, Benito, Pj, Gómez Lorente, Jj, Cañada, D, Urzanqui, A, Ortiz, Jc, Fuentes, F, Torres, Rm, and Paloma Navarro, T.

Subjects
Male, Pediatrics, medicine.medical_specialty, Percentile, Adolescent, Cross-sectional study, Population, Medicine (miscellaneous), Sex Factor, Severity of Illness Index, vitamin D deficiency, Body Mass Index, chemistry.chemical_compound, Sex Factors, Vitamin D and neurology, medicine, Prevalence, Humans, Age Factor, Obesity, Vitamin D, education, Child, Calcifediol, Cross-Sectional Studie, education.field_of_study, Nutrition and Dietetics, business.industry, Prevention, Age Factors, Urban Health, Nutrition Survey, Adolescent Development, medicine.disease, Nutrition Surveys, Vitamin D Deficiency, Europe, Cross-Sectional Studies, chemistry, Female, business, Body mass index, Demography, Human
Abstract

An adequate vitamin D status is essential during childhood and adolescence, for its important role in cell growth, skeletal structure and development. It also reduces the risk of conditions such as CVD, osteoporosis, diabetes mellitus, infections and autoimmune disease. As comparable data on the European level are lacking, assessment of vitamin D concentrations was included in the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study. Fasting blood samples were obtained from a subsample of 1006 adolescents (470 males; 46·8 %) with an age range of 12·5–17·5 years, selected in the ten HELENA cities in the nine European countries participating in this cross-sectional study, and analysed for 25-hydroxycholecalciferol (25(OH)D) by ELISA using EDTA plasma. As specific reference values for adolescents are missing, percentile distribution were computed by age and sex. Median 25(OH)D levels for the whole population were 57·1 nmol/l (5th percentile 24·3 nmol/l, 95th percentile 99·05 nmol/l). Vitamin D status was classified into four groups according to international guidelines (sufficiency/optimal levels ≥ 75 nmol/l; insufficiency 50–75 nmol/l; deficiency 27·5–49·99 nmol/l and severe deficiency P

Published
2011

6. Evaluation of iron status in European adolescents through biochemical iron indicators : the HELENA Study

Author

Ferrari, M, Mistura, L., Patterson, E., Sjöström, M., Díaz, L. E., Stehle, P., Gonzalez Gross, M., Kersting, M., Widhalm, K., Molnár, D., Gottrand, F., De Henauw, S., Manios, Y., Kafatos, A., Moreno, L. A., Leclercq, C., Luis A. Moreno LA, Gottrand F, De Henauw S, González Gross M, Gilbert C, Kafatos A, Moreno LA, Libersa C, Sáchez J, Kesting M, Sjostrom M, Molnár D, Gonzállez Gross M, Dallongeville J, Hall G, Maes L, Scalfi L, Fleta J, Casajús JA, Rodríguez G, Tomás C, Mesana MI, Vicente Rodríguez G, Villarroya A, Gil CM, Ara I, Revenga J, Lachen C, Alvira JF, Bueno G, Lázaro A, Bueno O, León JF, Garagorri JM, Bueno M, López JP, Iglesia I, Velasco P, Bel S, Marcos A, Wärnberg J, Nova E, Gómez S, Díaz EL, Romeo J, Veses A, Puertollano M, Zapatera B, Pozo T, Béghin L, Christian Libersa C, Catalina Iliescu C, Von Berlepsch J, Kersting MK, Sichert Hellert W, Koeppen E, Molnar D, Erhardt E, Csernus K, Török K, Bokor S, Angster, Nagy E, Kovács O, Repásy J, Codrington C, Plada M, Papadaki A, Sarri K, Viskadourou A, Hatzis C, Kiriakakis M, Tsibinos G, Sbokos CV, Protoyeraki E, Fasoulaki M, Stehle P, Pietrzik K, Breidenassel C, Spinneker A, Al Tahan J, Segoviano M, Berchtold A, Bierschbach C, Blatzheim E, Schuch A, Pickert P, Castillo MJ, Gutiérrez A, Ortega FB, Ruiz JR, Artero EG, España Romero V, Jiménez Pavon D, Chillón P, Arcella D, Azzini E, Barrison E, Bevilacqua N, Buonocore P, Catasta G, Censi L, Ciarapica D, D'Acapito P, Ferrari M, Galfo M, Le Donne C, Leclercq C, Maiani G, Mauro B, Mistura L, Piccinelli R, Polito A, Spada R, Sette S, Zaccaria M, Montagnese C, De Bourdeaudhuij I, De Vriendt T, Matthys C, Vereecken C, de Maeyer M, Ottevaere C, Widhalm K, Phillipp K, Dietrich S, Manios Y, Grammatikaki E, Bouloubasi Z, Cook TL, Eleutheriou S, Consta O, Moschonis G, Katsaroli I, Kraniou G, Papoutsou S, Keke D, Petraki I, Bellou E, Tanagra S, Kallianoti K, Argyropoulou D, Kondaki K, Tsikrika S, Karaiskos C, Meirhaeghe A, Sjöstrom M, Bergman P, Hagströmer M, Hallström L, Hallberg M, Poortvliet E, Wārnberg J, Rizzo N, Beckman L, Wennlöf AH, Patterson E, Kwak L, Cernerud L, Tillgren P, Sörensen S, Sánchez Molero J, Picó E, Navarro M, Viadel BV, Carreres JE, Merino G, Sanjuán R, Lorente M, Sánchez M, Castello S, Thomas S, Allchurch E, Burguess P, Astrom A, Sverkén A, Broberg A, Masson A, Lehoux C, Brabant P, Pate P, Fontaine L, Sebok A, Kuti T, Hegyi A, Maldonado C, Llorente A, García E, von Fircks H, Hallberg ML, Messerer M, Larsson M, Fredriksson H, Adamsson V, Börjesson I, Fernández L, Smillie L, Wills J, Meléndez A, Benito PJ, Calderón J, Jiménez Pavón D, Valtueña J, Navarro P, Urzanqui A, Albers U, Pedrero R, Lorente J.J., VITAGLIONE, PAOLA, Ferrari, M, Mistura, L., Patterson, E., Sjöström, M., Díaz, L. E., Stehle, P., Gonzalez Gross, M., Kersting, M., Widhalm, K., Molnár, D., Gottrand, F., De Henauw, S., Manios, Y., Kafatos, A., Moreno, L. A., Leclercq, C., Luis A., Moreno LA, Gottrand, F, De Henauw, S, González Gross, M, Gilbert, C, Kafatos, A, Moreno, La, Libersa, C, Sáchez, J, Kesting, M, Sjostrom, M, Molnár, D, Gonzállez Gross, M, Dallongeville, J, Hall, G, Maes, L, Scalfi, L, Fleta, J, Casajús, Ja, Rodríguez, G, Tomás, C, Mesana, Mi, Vicente Rodríguez, G, Villarroya, A, Gil, Cm, Ara, I, Revenga, J, Lachen, C, Alvira, Jf, Bueno, G, Lázaro, A, Bueno, O, León, Jf, Garagorri, Jm, Bueno, M, López, Jp, Iglesia, I, Velasco, P, Bel, S, Marcos, A, Wärnberg, J, Nova, E, Gómez, S, Díaz, El, Romeo, J, Veses, A, Puertollano, M, Zapatera, B, Pozo, T, Béghin, L, Christian Libersa, C, Catalina Iliescu, C, Von Berlepsch, J, Kersting, Mk, Sichert Hellert, W, Koeppen, E, Molnar, D, Erhardt, E, Csernus, K, Török, K, Bokor, S, Angster, Nagy, E, Kovács, O, Repásy, J, Codrington, C, Plada, M, Papadaki, A, Sarri, K, Viskadourou, A, Hatzis, C, Kiriakakis, M, Tsibinos, G, Sbokos, Cv, Protoyeraki, E, Fasoulaki, M, Stehle, P, Pietrzik, K, Breidenassel, C, Spinneker, A, Al Tahan, J, Segoviano, M, Berchtold, A, Bierschbach, C, Blatzheim, E, Schuch, A, Pickert, P, Castillo, Mj, Gutiérrez, A, Ortega, Fb, Ruiz, Jr, Artero, Eg, España Romero, V, Jiménez Pavon, D, Chillón, P, Arcella, D, Azzini, E, Barrison, E, Bevilacqua, N, Buonocore, P, Catasta, G, Censi, L, Ciarapica, D, D'Acapito, P, Galfo, M, Le Donne, C, Leclercq, C, Maiani, G, Mauro, B, Mistura, L, Piccinelli, R, Polito, A, Spada, R, Sette, S, Zaccaria, M, Vitaglione, Paola, Montagnese, C, De Bourdeaudhuij, I, De Vriendt, T, Matthys, C, Vereecken, C, de Maeyer, M, Ottevaere, C, Widhalm, K, Phillipp, K, Dietrich, S, Manios, Y, Grammatikaki, E, Bouloubasi, Z, Cook, Tl, Eleutheriou, S, Consta, O, Moschonis, G, Katsaroli, I, Kraniou, G, Papoutsou, S, Keke, D, Petraki, I, Bellou, E, Tanagra, S, Kallianoti, K, Argyropoulou, D, Kondaki, K, Tsikrika, S, Karaiskos, C, Meirhaeghe, A, Sjöstrom, M, Bergman, P, Hagströmer, M, Hallström, L, Hallberg, M, Poortvliet, E, Wārnberg, J, Rizzo, N, Beckman, L, Wennlöf, Ah, Patterson, E, Kwak, L, Cernerud, L, Tillgren, P, Sörensen, S, Sánchez Molero, J, Picó, E, Navarro, M, Viadel, Bv, Carreres, Je, Merino, G, Sanjuán, R, Lorente, M, Sánchez, M, Castello, S, Thomas, S, Allchurch, E, Burguess, P, Astrom, A, Sverkén, A, Broberg, A, Masson, A, Lehoux, C, Brabant, P, Pate, P, Fontaine, L, Sebok, A, Kuti, T, Hegyi, A, Maldonado, C, Llorente, A, García, E, von Fircks, H, Hallberg, Ml, Messerer, M, Larsson, M, Fredriksson, H, Adamsson, V, Börjesson, I, Fernández, L, Smillie, L, Wills, J, Meléndez, A, Benito, Pj, Calderón, J, Jiménez Pavón, D, Valtueña, J, Navarro, P, Urzanqui, A, Albers, U, Pedrero, R, Lorente, J. J., Applied Food Science, and Matthys, Christophe

Subjects
Male, 030309 nutrition & dietetics, Medicine (miscellaneous), CHILDREN, Sex Factor, RETINOL, 0302 clinical medicine, iron deficiency, Sex factors, Prevalence, Medicine and Health Sciences, adolescents, 030212 general & internal medicine, 10. No inequality, 0303 health sciences, Nutrition and Dietetics, Anemia, Iron-Deficiency, Nutritional status, Iron Deficiencies, Iron blood, 3. Good health, DEFICIENCY, Europe, Nutritional Statu, Original Article, Female, NUTRITION, Iron status, FERRITIN, Human, medicine.medical_specialty, Adolescent, European community, QUALITY-ASSURANCE, Adolescent Nutritional Physiological Phenomena, Iron, Nutritional Status, 03 medical and health sciences, Sex Factors, Environmental health, medicine, Humans, ANEMIA, Cross-Sectional Studie, Ferritin, Blood Chemical Analysis, anaemia, business.industry, Blood Chemical Analysi, Biomarker, Surgery, Cross-Sectional Studies, Multicenter study, adolescent, Ferritins, SOLUBLE TRANSFERRIN RECEPTOR, business, Biomarkers
Abstract

Background/Objectives: To assess the iron status among European adolescents through selected biochemical parameters in a cross-sectional study performed in 10 European cities. Subjects/Methods: Iron status was defined utilising biochemical indicators. Iron depletion was defined as low serum ferritin (SF8.5 mg/l) plus iron depletion. Iron deficiency anaemia (IDA) was defined as ID with haemoglobin (Hb) below the WHO cutoff for age and sex: 12.0 g/dl for girls and for boys aged 12.5–14.99 years and 13.0 g/dl for boys aged greater than or equal to15 years. Enzyme linked immunosorbent assay was used as analytical method for SF, sTfR and C-reactive protein (CRP). Subjects with indication of inflammation (CRP >5 mg/l) were excluded from the analyses. A total of 940 adolescents aged 12.5–17.49 years (438 boys and 502 girls) were involved. Results: The percentage of iron depletion was 17.6%, significantly higher in girls (21.0%) compared with boys (13.8%). The overall percentage of ID and IDA was 4.7 and 1.3%, respectively, with no significant differences between boys and girls. A correlation was observed between log (SF) and Hb (r=0.36, P, The HELENA Study was supported financially by the European Community Sixth RTD Framework Programme (Contract FOOD-CT-2005-007034).

Published
2011

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