1. [Peculiarities of formation, clinical presentations and therapy of diffuse nontoxic goiter of children].
- Author
-
Byriak VN and Murashko ES
- Subjects
- Child, Female, Genetic Predisposition to Disease, Goiter, Endemic genetics, Goiter, Endemic physiopathology, Goiter, Nodular genetics, Goiter, Nodular physiopathology, Humans, Iodine Compounds administration & dosage, Male, Pituitary Gland metabolism, Pituitary Gland physiopathology, Sex Factors, Thyroid Gland metabolism, Thyroid Gland physiopathology, Thyrotropin metabolism, Thyroxine administration & dosage, Thyroxine metabolism, Triiodothyronine metabolism, Goiter, Endemic therapy, Goiter, Nodular therapy, Hormone Replacement Therapy, Pituitary Gland drug effects, Thyroid Gland drug effects
- Abstract
The paper deals with the peculiarities of formation, clinical presentations and therapy of diffuse nontoxic goiter of children. The paper highlights the connection of the disease with the genetic predisposition, the impact of natural and anthropogenic strumagenes, immune processes. The clinical presentations of the diffuse nontoxic goiter are diffuse enlargement of thyroid gland, normal or high level of thyrotropichypophysis hormone when the content of thyroxin and triiodothyronine is normal, which is treated as the subclinic hypothyroidism syndrome. The variety of the disease pathogenesis theories leads to testing of different therapeutic methods, the principal ones among them are the use of iodine preparation and replacement therapy.
- Published
- 2012