1. Clinical features, biochemistry, and HLA‐DRB1 status in youth‐onset type 1 diabetes in Sudan
- Author
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Ibrahim, Tomader Ali Mohammed, Govender, Denira, Abdullah, Mohamed Ahmed, Noble, Janelle Annette, Hussien, Mohammed Osman, Lane, Julie Ann, Mack, Steven John, Martin, Gregory George Noble, Atkinson, Mark Alvin, Wasserfall, Clive Henry, and Ogle, Graham David
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Autoimmune Disease ,Diabetes ,Pediatric ,Clinical Research ,Metabolic and endocrine ,Adolescent ,Age of Onset ,Autoantibodies ,Biomarkers ,C-Peptide ,Case-Control Studies ,Child ,Child ,Preschool ,Diabetes Mellitus ,Type 1 ,Diabetic Ketoacidosis ,Female ,Genetic Predisposition to Disease ,Genotype ,Glutamate Decarboxylase ,HLA-DRB1 Chains ,Humans ,Infant ,Male ,Sudan ,autoantibodies ,childhood diabetes ,C‐ ,peptide ,HLA ,C-peptide ,Paediatrics and Reproductive Medicine ,Endocrinology & Metabolism ,Clinical sciences ,Paediatrics - Abstract
ObjectiveTo further understand clinical and biochemical features, and HLA-DRB1 genotypes, in new cases of diabetes in Sudanese children and adolescents.Research design and methodsDemographic characteristics, clinical information, and biochemical parameters (blood glucose, HbA1c, C-peptide, autoantibodies against glutamic acid decarboxylase 65 [GADA] and insulinoma-associated protein-2 [IA-2A], and HLA-DRB1) were assessed in 99 individuals
- Published
- 2021