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2 results on '"Cross GB"'

1. Short Communication: Mycobacterium avium Complex Infection and Immune Reconstitution Inflammatory Syndrome Remain a Challenge in the Era of Effective Antiretroviral Therapy.

Author

Smibert OC, Trubiano JA, Cross GB, and Hoy JF

Subjects
Adult, Clarithromycin therapeutic use, Drug Therapy, Combination, Ethambutol therapeutic use, Female, Humans, Immune Reconstitution Inflammatory Syndrome drug therapy, Male, Middle Aged, Mycobacterium avium Complex immunology, Mycobacterium avium Complex pathogenicity, Mycobacterium avium-intracellulare Infection immunology, Rifabutin therapeutic use, AIDS-Related Opportunistic Infections drug therapy, Anti-HIV Agents therapeutic use, Antiretroviral Therapy, Highly Active, HIV Infections drug therapy, Immune Reconstitution Inflammatory Syndrome pathology, Mycobacterium avium-intracellulare Infection drug therapy, Mycobacterium avium-intracellulare Infection pathology
Abstract

A 10-year review of disseminated Mycobacterium avium complex (MAC) infection and MAC-immune reconstitution inflammatory syndrome in HIV-positive patients (2004-2014) at a state-wide tertiary referral HIV service demonstrates that despite advances in antiretroviral therapy, MAC infection remains a therapeutic challenge, particularly intra-abdominal disease.

Published
2017
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2. Mycobacterium haemophilum bone and joint infection in HIV/AIDS: case report and literature review.

Author

Cross GB, Le Q, Webb B, Jenkin GA, Korman TM, Francis M, and Woolley I

Subjects
AIDS-Related Opportunistic Infections diagnosis, AIDS-Related Opportunistic Infections microbiology, Adult, Ankle Joint, Anti-Bacterial Agents therapeutic use, Anti-HIV Agents therapeutic use, Debridement, HIV Infections drug therapy, Humans, Immune Reconstitution Inflammatory Syndrome microbiology, Magnetic Resonance Imaging, Male, Middle Aged, Mycobacterium Infections drug therapy, Mycobacterium Infections microbiology, Mycobacterium haemophilum genetics, Osteomyelitis diagnosis, Osteomyelitis therapy, Polymerase Chain Reaction, Tenosynovitis microbiology, Tenosynovitis surgery, AIDS-Related Opportunistic Infections drug therapy, HIV Infections complications, Immune Reconstitution Inflammatory Syndrome complications, Mycobacterium Infections diagnosis, Mycobacterium haemophilum isolation & purification, Osteomyelitis microbiology
Abstract

We report a case of disseminated Mycobacterium haemophilum osteomyelitis in a patient with advanced HIV infection, who later developed recurrent immune reconstitution inflammatory syndrome after commencement of antiretroviral therapy. We review previous reports of M. haemophilum bone and joint infection associated with HIV infection and describe the management of M. haemophilum-associated immune reconstitution inflammatory syndrome, including the role of surgery as an adjunctive treatment modality and the potential drug interactions between antiretroviral and antimycobacterial agents., (© The Author(s) 2015.)

Published
2015
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