5 results on '"reactive lesions"'
Search Results
2. Epulis: a study of 92 cases with special emphasis on histopathological diagnosis and associated clinical data.
- Author
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Truschnegg, Astrid, Acham, Stephan, Kiefer, Birgit, Jakse, Norbert, and Beham, Alfred
- Subjects
- *
HISTOPATHOLOGY , *FIBROMAS , *ORAL surgery , *ORAL hygiene , *RADIOLOGY , *DIAGNOSIS - Abstract
Objectives: Aim of the present study was clinical and histopathological evaluation of a series of epulides to provide clinicians data to frequency distribution and biological behaviour of different underlying entities. Materials and methods: Ninety-two cases of epulides removed by CO-laser at the Department of Oral Surgery and Radiology, Medical University of Graz from 2000 to 2014 were studied retrospectively for clinical data and histopathological diagnosis. Results: In the presented study, histopathological examination revealed peripheral ossifying fibroma (32.6 %), fibroma/fibrosis (29.3 %), giant cell lesion (13.1 %) and granuloma pyogenicum (8.7 %) as the most frequent underlying entities. For the first time, hyperplastic squamous epithelium (7.6 %), granulation tissue (5.4 %) and peripheral odontogenic fibromas (3.3 %) were detected to clinically appear as epulides. Irrespective of the histological diagnosis, the mean age in our patients was 43.8 years. The majority of the lesions were found in the frontal region of both jaws. In all cases, the patients showed poor oral hygiene, local gingivitis and some of them an occlusal trauma. Conclusions: To identify different entities with different biological behaviour, to exclude malignant tumours and to identify new entities among epulides, histopathological examination is required. Poor oral hygiene and occlusal trauma seem to play an important role in the pathogenesis and could be risk factors for recurrences. Clinical relevance: Frequency distribution of different entities in epulides is provided to clinicians, and new histopathological entities were detected to clinically appear as epulides. [ABSTRACT FROM AUTHOR]
- Published
- 2016
- Full Text
- View/download PDF
3. Analysis of gingival biopsies in the Gujarati population: A retrospective study.
- Author
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Manjunatha, Bhari Sharanesha, Sutariya, Rakesh, Nagamahita, V., Dholia, Bhavik, and Shah, Vandana
- Subjects
- *
GINGIVA surgery , *BIOPSY , *ORAL diseases , *GUJARATIS (Indic people) , *HYPERPLASIA - Abstract
Background: Biopsy is an important diagnostic tool used in the diagnosis of lesions ranging from simple non-neoplastic, tumor-like lesions to malignancies, and is often the only way to diagnose oral lesions and diseases. The gingiva is the most common site for some kind of irritation or low-grade injury, resulting in localized overgrowths that are considered to be reactive and non-neoplastic lesions. This aim of this study is to analyze the frequency and distribution of gingival lesions in the Gujarati population. Materials and Methods: In this retrospective study, gingival biopsies submitted for a period of five years were included. Microscopic slides of all the cases were reviewed by two observers for confirmation of the diagnosis. Results: Among the 106 cases of gingival biopsies, the most frequent category of lesions encountered was the non-neoplastic category, which accounted for 73.58% of the cases. Both benign and malignant neoplasms constituted 26.42% of the cases. Among the non-neoplastic lesions, Pyogenic granuloma was the most frequent lesion (38.46%), followed by fibrous hyperplasia (20.51%), inflammatory hyperplasia (19.23%), and Epulis (8.97%). Neoplasms accounted for 26.42% of the gingival biopsies (92.85% benign and 7.15% malignant). Among the benign neoplastic lesions, Fibroma (30.76%) and Fibrolipoma (26.92%) were the most frequent, followed by peripheral ossifying fibroma (23.08%) and peripheral giant cell granuloma (11%). Conclusion: It is difficult to compare studies carried out in various countries due to differences in people's attitudes toward oral health and the accessibility of various population groups to biopsy services. Nevertheless, this study has provided some information about the frequency and distribution of biopsied gingival lesions in the Gujarati population over a period of five years. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
4. Cocktail of Periodic Acid-Schiff and Papanicolaou: Novel staining technique for the identification of leukemic eosinophils - A pilot study
- Author
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Vanishri C Haragannavar, S. V. Sowmya, Dominic Augustine, Roopa S Rao, Lavanya Mallika, and K. Shwetha Nambiar
- Subjects
0301 basic medicine ,Pathology ,medicine.medical_specialty ,Papanicolaou stain ,Periodic acid–Schiff stain ,Stain ,Pathology and Forensic Medicine ,Pathogenesis ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Eosinophilia ,General Dentistry ,business.industry ,leukemia ,medicine.disease ,Staining ,Eosinophils ,Leukemia ,030104 developmental biology ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Histopathology ,Original Article ,reactive lesions ,medicine.symptom ,business - Abstract
Background: Tissue eosinophilia may be caused due to reactive, neoplastic or idiopathic reasons. Reactive eosinophils in allergic and inflammatory conditions are transient and recruited from the circulation in response to various stimuli, whereas neoplastic eosinophils of leukemias and hematological malignancies are involved in the pathogenesis of the disease. The differentiation of reactive from neoplastic eosinophils has a serious implication on the treatment and prognosis of diseases. However, both these types of eosinophils display variation in morphology and staining characteristics in routine histopathology leading to a diagnostic dilemma. Aim: The aim of this study is to evaluate the efficacy of special stains for the demonstration of eosinophils in normal/reactive lesions and leukemias. Methodology: A retrospective study comprising twenty histologically diagnosed cases each of reactive oral lesions and leukemias were obtained from institutional archives. These tissue sections were subjected to staining with routine and special stains – Carbol chromotrope, Congo red, Leishman's stain, Periodic Acid–Schiff-papanicolaou (PAS-PAP) and PAS. Statistical analysis was performed using Pearson's Chi-square test to compare the various parameters in the evaluation of the staining efficacy. Results: Carbol chromotrope and Congo red staining showed increased staining efficacy in normal/reactive eosinophils while PAS-PAP followed by PAS and Leishman's stain showed enhanced features such as homogenicity, specificity, increased staining intensity, enhanced nuclear and cytoplasmic details in leukemic eosinophils. Conclusion: Combined PAS-PAP is a novel and cost-effective staining technique in differentiating reactive and leukemic eosinophils. It is significant in recognizing leukemic eosinophils of routine biopsies and alerts the clinician to rule out any underlying malignancies.
- Published
- 2020
5. Analysis of gingival biopsies in the Gujarati population: a retrospective study
- Author
-
Bhari Sharanesha Manjunatha, Rakesh Sutariya, Bhavik Dholia, Vandana Shah, and V Nagamahita
- Subjects
Male ,Pathology ,Epulis ,Biopsy ,Gingiva ,pyogenic granuloma ,Child ,Observer Variation ,education.field_of_study ,Granuloma ,medicine.diagnostic_test ,Peripheral ossifying fibroma ,General Medicine ,Middle Aged ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Peripheral giant-cell granuloma ,Oncology ,Fibroma, Ossifying ,histopathology ,Female ,gingival biopsy ,Lipoma ,Adult ,medicine.medical_specialty ,Adolescent ,Population ,India ,Fibroma ,lcsh:RC254-282 ,Benign and malignant tumors ,Young Adult ,Sex Factors ,Granuloma, Giant Cell ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,education ,Aged ,Retrospective Studies ,Gingival Neoplasms ,Hyperplasia ,Pyogenic granuloma ,business.industry ,medicine.disease ,Dermatology ,Gingival Diseases ,giant-cell granuloma ,Histopathology ,reactive lesions ,business ,Mouth Diseases - Abstract
Background: Biopsy is an important diagnostic tool used in the diagnosis of lesions ranging from simple non-neoplastic, tumor-like lesions to malignancies, and is often the only way to diagnose oral lesions and diseases. The gingiva is the most common site for some kind of irritation or low-grade injury, resulting in localized overgrowths that are considered to be reactive and non-neoplastic lesions. This aim of this study is to analyze the frequency and distribution of gingival lesions in the Gujarati population. Materials and Methods: In this retrospective study, gingival biopsies submitted for a period of five years were included. Microscopic slides of all the cases were reviewed by two observers for confirmation of the diagnosis. Results: Among the 106 cases of gingival biopsies, the most frequent category of lesions encountered was the non-neoplastic category, which accounted for 73.58% of the cases. Both benign and malignant neoplasms constituted 26.42% of the cases. Among the non-neoplastic lesions, Pyogenic granuloma was the most frequent lesion (38.46%), followed by fibrous hyperplasia (20.51%), inflammatory hyperplasia (19.23%), and Epulis (8.97%). Neoplasms accounted for 26.42% of the gingival biopsies (92.85% benign and 7.15% malignant). Among the benign neoplastic lesions, Fibroma (30.76%) and Fibrolipoma (26.92%) were the most frequent, followed by peripheral ossifying fibroma (23.08%) and peripheral giant cell granuloma (11%). Conclusion: It is difficult to compare studies carried out in various countries due to differences in people's attitudes toward oral health and the accessibility of various population groups to biopsy services. Nevertheless, this study has provided some information about the frequency and distribution of biopsied gingival lesions in the Gujarati population over a period of five years.
- Published
- 2015
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