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Your search keyword '"Napolov IuK"' showing total 4 results
Start Over Author "Napolov IuK" Topic histamine release
4 results on '"Napolov IuK"'

1. [The mechanism of histamine liberation from rat mast cells under the action of x-ray contrast media].

Author

Napolov IuK

Subjects
Animals, Mast Cells physiology, Peritoneal Cavity cytology, Rats, Rats, Wistar, Statistics, Nonparametric, Cell Degranulation drug effects, Contrast Media pharmacology, Diatrizoate Meglumine pharmacology, Histamine Release drug effects, Iodamide pharmacology, Iodine Radioisotopes pharmacology, Iodipamide pharmacology, Mast Cells drug effects
Abstract

It was demonstrated in rat experiments that a positive direct correlation exists between the decrease in the amount of histamine in rat peritoneal must cells after intravenous infusion of radiopaque agents (ROA) in a dose of 2 ml/kg and the amount of these penetrating from the blood into the peritoneal cavity. The degree of penetration is determined by the chemical structure and/or physiochemical properties of the ROA.

Published
1997

2. [On a mechanism of histamine-liberating effect of radiocontrast media].

Author

Sergeev PV, Napolov IuK, and Shimanovskiĭ NL

Subjects
Animals, Basophils drug effects, Basophils metabolism, Calcium blood, Histamine blood, In Vitro Techniques, Mast Cells drug effects, Mast Cells metabolism, Rabbits, Contrast Media toxicity, Histamine Release drug effects
Published
1996

3. [Histamine-releasing action of x-ray contrast media in rats in vivo].

Author

Napolov IuK, Zanina EN, Panov VO, and Shimanovskiĭ NL

Subjects
Animals, Dose-Response Relationship, Drug, Female, Histamine analysis, Male, Mast Cells analysis, Mast Cells drug effects, Peritoneal Cavity cytology, Rats, Rats, Inbred Strains, Spectrometry, Fluorescence, Contrast Media pharmacology, Histamine Release drug effects
Abstract

The effect of roentgen contrast media (RCM)--50% bilignost, 76% triombrast, 80% iodamide-380, on degranulation of peritoneal mast cells in rats was studied. It was found that 20 minutes after intravenous injections of RCM the content of intracellular histamine significantly decreased. This effect depended on the drug dose and increased in the order: triombrast, iodamide, triiotrast, bilignost. Different sensitivity of animals to the histamine-releasing effect of RCM was detected by using the nonparametric method of mathematical statistics. The number of "sensitive" animals was 50-75%.

Published
1988

4. [Histamine-liberating action of x-ray contrast media].

Author

Shimanovskiĭ NL, Napolov IuK, and Sergeev PV

Subjects
Anaphylaxis chemically induced, Anaphylaxis diagnosis, Anaphylaxis prevention & control, Animals, Contrast Media toxicity, Drug Hypersensitivity diagnosis, Drug Hypersensitivity etiology, Drug Hypersensitivity prevention & control, Humans, Prognosis, Contrast Media adverse effects, Histamine Release drug effects
Published
1988

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