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Szymczak, Robert K., Magdalena Sawicka, and Małgorzata Jelitto. Recurrent pulmonary embolism at high altitude in a mountaineer with hereditary thrombophilia. High Alt Med Biol. 25:345–347, 2024.—It is speculated that high-altitude travel is an independent risk factor for thrombosis. Mountaineering-specific factors, such as hypoxia, cold, and immobilization, may interact with patient-specific risk factors and contribute to thrombus formation. We present the case of a mountaineer with hereditary thrombophilia who experienced recurrent pulmonary embolism during high-altitude expeditions. [ABSTRACT FROM AUTHOR]

Keywords: high altitude; neurodegeneration; inherited disease; Spinocerebellar ataxia EN high altitude neurodegeneration inherited disease Spinocerebellar ataxia 1 3 3 08/24/22 20220701 NES 220701 Case presentation A 28-year-old man from Poland began to experience disturbances in gait and balance above 4150 m, while climbing one of the 7000 m peaks in Karakoram - the second highest mountain range on Earth (Figure 1). High altitude, neurodegeneration, inherited disease, Spinocerebellar ataxia. [Extracted from the article]

Keywords: Paradoxical embolism; patent foramen ovale; ischaemic stroke; high altitude EN Paradoxical embolism patent foramen ovale ischaemic stroke high altitude 1 3 3 08/24/22 20220701 NES 220701 Case Presentation A 30-year-old Polish woman noticed a sudden loss of visual field on her right side while at 4450 m on the eighth day of trekking around Annapurna in the Himalayas (Figure 1). Paradoxical embolism, patent foramen ovale, ischaemic stroke, high altitude No other potential causes of ischaemic stroke were found, therefore the most likely aetiology of stroke was considered to be the mechanism of paradoxical embolism through PFO. [Extracted from the article]