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Your search keyword '"M. Dolenc-Voljc"' showing total 4 results
Start Over Author "M. Dolenc-Voljc" Topic hidradenitis suppurativa
4 results on '"M. Dolenc-Voljc"'

1. Clinical characteristics of pediatric hidradenitis suppurativa: a cross-sectional multicenter study of 140 patients.

Author

Riis PT, Saunte DM, Sigsgaard V, Villani AP, Guillem P, Pascual JC, Kappe NN, Vanlaerhoven AMJD, van der Zee HH, Prens EP, El-Domyati M, Abdel-Wahab H, Moftah N, Abdelghani R, Agut-Busquet E, Romaní J, Hlela C, van den Worm L, Bettoli V, Calamo G, Gürer MA, Beksaç B, Matusiak L, Glowaczewska A, Szepietowski JC, Emtestam L, Lapins J, Kottb HR, Fatani M, Weibel L, Theiler M, Delage-Toriel M, Lam TTH, Nassif A, Becherel PA, Dolenc-Voljc M, Doss N, Bouazzi D, Benhadou F, Del Marmol V, and Jemec GBE

Subjects
Acne Vulgaris epidemiology, Administration, Cutaneous, Administration, Oral, Adolescent, Body Mass Index, Child, Clindamycin administration & dosage, Comorbidity, Cross-Sectional Studies, Drug Therapy, Combination methods, Female, Hidradenitis Suppurativa epidemiology, Hirsutism epidemiology, Humans, Male, Pilonidal Sinus epidemiology, Resorcinols administration & dosage, Rifampin administration & dosage, Risk Factors, Severity of Illness Index, Tetracycline administration & dosage, Treatment Outcome, Young Adult, Anti-Bacterial Agents administration & dosage, Dermatologic Surgical Procedures, Hidradenitis Suppurativa therapy, Obesity epidemiology, Smoking epidemiology
Abstract

Hidradenitis suppurativa (HS) rarely affects pediatric patients. The literature on pediatric HS patients is scarce. This is a cross-sectional study based on case note review or interviews and clinical examination of 140 pediatric patients undergoing secondary or tertiary level care. Patients were predominantly female (75.5%, n = 105) with a median age of 16. 39% reported 1st-degree relative with HS. Median BMI percentile was 88, and 11% were smokers (n = 15). Median modified Sartorius score was 8.5. Notable comorbidities found were acne (32.8%, n = 45), hirsutism (19.3%, n = 27), and pilonidal cysts (16.4%, n = 23). Resorcinol (n = 27) and clindamycin (n = 25) were the most frequently used topical treatments. Patients were treated with tetracycline (n = 32), or oral clindamycin and rifampicin in combination (n = 29). Surgical excision was performed in 18 patients, deroofing in five and incision in seven patients. Obesity seemed to be prominent in the pediatric population and correlated to parent BMI, suggesting a potential for preventive measures for the family. Disease management appeared to be similar to that of adult HS, bearing in mind that the younger the patient, the milder the disease in majority of cases.

Published
2020
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2. Low and high body mass index in hidradenitis suppurativa patients-different subtypes?

Author

Theut Riis P, Saunte DM, Benhadou F, Del Marmol V, Guillem P, El-Domyati M, Abdel-Wahab H, Antoniou C, Dessinioti C, Gürer MA, Beksaç B, Szepietowski JC, Matusiak L, Emtestam L, Lapins J, Riad H, Doss N, Massa AF, Hamzavi I, Nicholson C, Dolenc-Voljc M, Kim KH, Ohn J, Zouboulis CC, Karagiannidis I, Mokos ZB, Durinec P, and Jemec GBE

Subjects
Adult, Age of Onset, Cross-Sectional Studies, Female, Hidradenitis Suppurativa complications, Humans, Male, Obesity complications, Protective Factors, Risk Factors, Smoking, Young Adult, Body Mass Index, Hidradenitis Suppurativa classification, Hidradenitis Suppurativa genetics, Severity of Illness Index
Abstract

Introduction: Overweight is a well-established risk factor for hidradenitis suppurativa (HS). In this cross-sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics., Materials and Method: Patients were recruited from 17 dermatological centres from four continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35., Results: Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient-reported severity (PRS), P < 0.001 for all). There was no difference in smoking (P = 0.783) nor in family history (P = 0.088). In both low and high BMI patients, early onset of HS was a predictor of positive family history (P < 0.001, for each). For low BMI patients, an increase in BMI significantly increased PRS (P < 0.001). For patients with a high BMI, number of pack-years significantly increased PRS (P = 0.001). Cluster analysis of eruption patterns was location specific for low BMI patients but severity specific for high BMI patients., Discussion: Patients with a low and high BMI could represent two clinically different subtypes. We suggest a non-linear relationship between BMI and impact of HS. As patients go from a low BMI patient to a high BMI patient (or from high to low), eruption patterns and risk factors may change., (© 2017 European Academy of Dermatology and Venereology.)

Published
2018
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3. Diagnostic delay in hidradenitis suppurativa is a global problem.

Author

Saunte DM, Boer J, Stratigos A, Szepietowski JC, Hamzavi I, Kim KH, Zarchi K, Antoniou C, Matusiak L, Lim HW, Williams M, Kwon HH, Gürer MA, Mammadova F, Kaminsky A, Prens E, van der Zee HH, Bettoli V, Zauli S, Hafner J, Lauchli S, French LE, Riad H, El-Domyati M, Abdel-Wahab H, Kirby B, Kelly G, Calderon P, del Marmol V, Benhadou F, Revuz J, Zouboulis CC, Karagiannidis I, Sartorius K, Hagströmer L, McMeniman E, Ong N, Dolenc-Voljc M, Mokos ZB, Borradori L, Hunger RE, Sladden C, Scheinfeld N, Moftah N, Emtestam L, Lapins J, Doss N, Kurokawa I, and Jemec GB

Subjects
Adolescent, Adult, Age of Onset, Aged, Child, Female, Global Health, Humans, Male, Middle Aged, Psoriasis diagnosis, Time-to-Treatment, Young Adult, Delayed Diagnosis, Hidradenitis Suppurativa diagnosis
Published
2015
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4. Low and high body mass index in hidradenitis suppurativa patients-different subtypes?

Author

Z. B. Mokos, Clio Dessinioti, N. Doss, A. F. Massa, V. Del Marmol, Gregor B.E. Jemec, M. Dolenc-Voljc, P. Theut Riis, Farida Benhadou, Jungyoon Ohn, C. Nicholson, Mehmet Ali Gürer, Jan Lapins, Jacek C Szepietowski, Ditte Marie Saunte, Ch. Antoniou, Lukasz Matusiak, Hossam Abdel-Wahab, Ioannis Karagiannidis, Moetaz El-Domyati, Lennart Emtestam, H. Riad, Iltefat H. Hamzavi, Philippe Guillem, P. Durinec, Kyu Han Kim, Burcu Beksaç, and Christos C. Zouboulis

Subjects
Adult, Male, medicine.medical_specialty, Cross-sectional study, Dermatology, Overweight, Severity of Illness Index, Body Mass Index, 030207 dermatology & venereal diseases, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Risk Factors, Internal medicine, Severity of illness, medicine, Humans, Hidradenitis suppurativa, Obesity, Family history, Risk factor, Age of Onset, business.industry, Smoking, nutritional and metabolic diseases, Protective Factors, medicine.disease, Surgery, Hidradenitis Suppurativa, Infectious Diseases, Cross-Sectional Studies, 030220 oncology & carcinogenesis, hidradenitis suppurativa, body mass index, Female, Age of onset, medicine.symptom, business, Body mass index
Abstract

Introduction Overweight is a well established risk factor for Hidradenitis Suppurativa (HS). In this cross sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics. Materials and method Patients were recruited from 17 dermatological centers from 4 continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35. Results Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient reported severity, p < 0.001 for all). There was no difference in smoking (p = 0.783) nor in family history (p = 0.088). In both low and high BMI patients, early onset of HS was a predictor of positive family history (p < 0.001, for each). For low BMI patients, an increase in BMI significantly increased patient reported severity (p < 0.001). For patients with a high BMI, number of pack years significantly increased patient reported severity (p = 0.001). Cluster analysis of eruption patterns were location specific for low BMI patients but severity specific for high BMI patients. Discussion Patients with a low and high body mass index could represent two clinically different subtypes. We suggest a non-linear relationship between BMI and impact of HS. As patients go from a low BMI patient to a high BMI patient (or from high to low), eruption patterns and risk factors may change. This article is protected by copyright. All rights reserved.

Published
2017

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