1. [The determination of the level of antibodies to Epstein-Barr virus antigens in organizing groups at high risk for lung cancer disease].
- Author
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Zyrianov BN, Podoplekin VD, Siianov VS, Kuznetsova TI, and Tuzikov SA
- Subjects
- Adenocarcinoma immunology, Adult, Antibody Specificity immunology, Carcinoma, Squamous Cell immunology, Fluorescent Antibody Technique, Humans, Immunoglobulin A analysis, Immunoglobulin G analysis, Lung Diseases, Obstructive immunology, Lung Neoplasms immunology, Risk Factors, Seroepidemiologic Studies, Adenocarcinoma epidemiology, Antibodies, Viral analysis, Antigens, Viral immunology, Carcinoma, Squamous Cell epidemiology, Herpesvirus 4, Human immunology, Lung Neoplasms epidemiology
- Abstract
Titers of antibodies against Epstein-Barr virus (EBV) antigen were measured in 450 subjects aged 40 years and older. The group included patients with lung cancer, cases of non-specific chronic lung pathology and healthy subjects (150 persons in each subset). A significant increase in the level of antibodies to capsid EBV antigen was established in patients with lung cancer and chronic non-specific lung pathology as compared to healthy controls. Parameters of specific immunologic response to Epstein-Barr virus may be recommended as additional criteria for inclusion into the group at risk for lung cancer.
- Published
- 1990