1. High level of exposure to hepatitis B virus infection in a vulnerable population of a low endemic area: A challenge for vaccination coverage.
- Author
-
Weis-Torres SMDS, Fitts SMF, Cardoso WM, Higa Junior MG, Lima LA, Bandeira LM, Castro VOL, Carneiro FA, Iglecias LMM, Cesar GA, Tanaka TSO, Puga MAM, Rezende GR, Croda J, Lago BV, and Motta-Castro ARC
- Subjects
- Adolescent, Adult, Brazil epidemiology, Cross-Sectional Studies, Endemic Diseases prevention & control, Endemic Diseases statistics & numerical data, Female, Hepatitis B epidemiology, Hepatitis B virology, Hepatitis B Antibodies immunology, Hepatitis B Surface Antigens immunology, Hepatitis B Vaccines immunology, Hepatitis B virus genetics, Humans, Male, Middle Aged, Prevalence, Vaccination statistics & numerical data, Vaccination Coverage statistics & numerical data, Vulnerable Populations statistics & numerical data, Young Adult, Hepatitis B prevention & control, Hepatitis B Surface Antigens administration & dosage, Hepatitis B Vaccines administration & dosage, Hepatitis B virus immunology
- Abstract
Objectives: To evaluate the epidemiological and molecular features of HBV infection among recyclable waste collectors., Methods: The participants were recruited from the dumping ground and recycling cooperatives in Campo Grande, Brazil, and were screened for hepatitis B and C, and HIV serological markers by ELISA, confirmed by PCR., Results: Among 278 participants, 63.7% (95% CI: 58.0-69.3) were considered susceptible to HBV infection. The prevalence rate of HBV exposure was 10.1% (95% CI: 6.5-13.6) and 0.4% (95% CI: 0.1-0.6) were chronic carriers. Age ≥45 years (AOR=7.15), history of homosexual contact (AOR=5.29), tattoo (AOR=4.92) and history of surgery (AOR=2.89) were factors associated with ever infection. Age 18-25 years (AOR=4.63), educational level ≥9 years (AOR=1.98) and knowledge about HBV transmission (AOR=3.08) were associated with serological HBV vaccination like profile (26.2%; 95% CI: 21.1-31.4)., Conclusions: Despite the availability and efficacy of HBV vaccine, this study found high HBV exposure and proportion of susceptible adults in a low endemic area. Vaccination and screening campaigns using accessible language to the economically disadvantaged populations can reduce the number of people susceptible to HBV infection., (Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF