1. Effect of Liangxuehuayu Recipe on hemorheology in rats with blood stasis syndrome.
- Author
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Ning SY, Jiang BP, Xu L, Fang TH, and Wu MH
- Subjects
- Analysis of Variance, Animals, Blood Viscosity drug effects, Cell Aggregation drug effects, Erythrocytes drug effects, Erythrocytes pathology, Male, Rats, Rats, Sprague-Dawley, Drugs, Chinese Herbal pharmacology, Hematologic Diseases blood, Hemorheology drug effects
- Abstract
Objective: To investigate the effects of Liangxuehuayu Recipe on hemorheology in rats with blood stasis syndrome induced by mutifactor stimuli., Methods: SD rats were divided into control, model, Liangxuehuayu Recipe (high, middle and low dose, 18, 9, 4.5 g/kg accordingly). Except the control group, blood stasis model was established in the rest groups. The hemorheological parameters were measured and compared., Results: Blood viscosity at high, moderate and low level in rats with blood stasis significantly increased (P<0.05), but blood viscosity at high level and plasma viscosity was significantly decreased in rats induced by some stimuli after Liangxuehuayu Recipe were intra-gastrically administered for 1 weeks (P<0.01, P<0.05)., Conclusions: Liangxuehuayu Recipe is effective in improving hemorheology, and has important application value in the prevention of occurrence and development of ischemic stroke., (Copyright © 2012 Hainan Medical College. Published by Elsevier B.V. All rights reserved.)
- Published
- 2012
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