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Changes in hemodynamics and some metabolic parameters were studied in 78 patients during anesthesia for resection of the abdominal aorta aneurysms. The steps of the operation associated with the most profound hemodynamic changes were distinguished and measures aimed at stabilization of hemodynamics, blood volume, and electrolyte balance considered. No appreciable changes in the hemodynamics or depression of the myocardium were observed at stages of anesthesia and operation. A correlation was traced between pressure changes in the pulmonary artery and central venous pressure. The suggested method of anesthesia and infusion therapy strategy are conducive to stabilization of the hemodynamics in the course of the whole operation, to maintenance of normal volume of circulating blood and adequate diuresis. Monitoring of central venous pressure is sufficient to control infusion therapy and hemodynamics.

Cardiac hemodynamics and myocardial contractility were examined in patients with acute myocardial infarction during urgent aorto-coronary shunting with and without beta-adrenergic blockers. The beta-blockers were shown to have a protective effect, as reflected in a smaller myocardial strain owing to a decrease in heart rate, stroke and cardiac outputs, and pulmonary arterial blood pressure. Propranolol proved the most effective agent, whereas visken produced the smallest effect.