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Introduction: Dyspepsia comprises a group of symptoms that can have organic or functional origin. The purpose of this study was to describe the main causes of dyspepsia and its clinical evolution in children cared for in a tertiary care hospital., Material and Methods: Retrospective study in children with dyspepsia. Patients underwent endoscopy with biopsy and rapid urease test to detect the presence of Helicobacter pylori. In case of normal endoscopy and biopsy, hydrogen breath test was performed. In all cases, follow-up was provided in order to evaluate symptom improvement., Results: One hundred children were included, out of whom 52 were girls; mean age was 8.59 years. Esophagitis or erosive gastropathy were found in 54% of the cases (n = 54), H. pylori infection in 12% (n = 12), small intestinal bacterial overgrowth in 12% (n = 12), and functional dyspepsia in 20% (n = 20)., Conclusion: In children with dyspepsia, organic causes should first be ruled out before dyspepsia being characterized as functional. In general terms, we consider that a stepped approach that includes endoscopy with biopsy, search for H. pylori and hydrogen breath test is necessary., (Copyright: © 2021 Permanyer.)

Background: Different antibiotics, antagonist H2 and others have been used for elimination and/or eradication of Helicobacter pylori., Aims: Evaluate elimination of Helicobacter pylori with amoxicillin, bismuth subsalicylate and ranitidine; and the improvement of recurrent abdominal pain., Method: 20 children with recurrent abdominal pain associated to gastritis and histologic identification of Helicobacter pylori were studied under a period of 18 months (January 1992 to June 1993), at Instituto Nacional de Pediatría, México, D.F. All children were treated simultaneously with: Amoxicillin, 15 days, plus ranitidine and bismuth subsalicylate for one month., Results: Helicobacter pylori was eliminated in 14 of 20 children studied. All these children had an important improvement of recurrent abdominal pain., Conclusion: Elimination of Helicobacter pylori and clinical improvement was present in 14 of 20 children studied (70%).

Objective: Elimination of Helicobacter pylori with Chlaritromicin, Bismuth subsalicylate and Ranitidine; and improvement of recurrent abdominal pain. ANTECEDENT: Different antibiotics, antagonist H2 and others has been used for elimination and, or eradication of Helicobacter pylori., Method: 22 children with recurrent abdominal pain associated to gastritis and histologic identification of Helicobacter pylori were studied under a period of 18 months (january 1992 to june 1993), at Instituto Nacional de Pediatría, México, D:F: All children were treated simultaneously with: Chlaritromicin, 15 days, Plus ranitidine and bismuth subsalicylate for one month., Results: Helicobacter pylori was eliminate in 14 of 22 children studied. All these children had an important improvement of recurrent abdominal pain., Conclusion: Elimination of Helicobacter pylori and clinical improvement was present in 14 of 22 children studied (63.7%).

We studied 40 children with recurrent abdominal pain during a period of six months (january to june 1993) entered at the gastroenterology service of the Instituto Nacional de Pediatria in México City. In all of then we performed in all of them an upper gastrointestinal endoscopy with 3 biopsies from gastric mucosa (antrum) for histological examination and urease tests. We also did an ELISA test looking for an H. Pylori specific serum IgG response. Our control group were 40 healthy children in whom we did only the ELISA test. We did not find any statistics differences between the histologic findings (gold standard) and the urease and ELISA tests. With IgG antibodies prevalence for H. Pylori in children with recurrent abdominal pain were 57% in contrast with our control group in whom the prevalence was 5%.

Helicobacter pylori is a recently identified microorganisms which is thought to be the causing agent of the peptic acid disease in children as well as in adults. It is currently accepted that frequent relapses of this illness in spite of an adequate treatment can be associated to the faulty eradication of this bacteria. This article outlines the characteristics of H. pylori, its incidence, pathogenesis, as well as the current diagnostic methods used and the treatment applied.