1. Percutaneous management of a Fontan fenestration: in search for the ideal restriction-occlusion device.
- Author
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Boshoff DE, Brown SC, Degiovanni J, Stumper O, Wright J, Mertens L, and Gewillig M
- Subjects
- Belgium, Cardiac Catheterization adverse effects, Child, Child, Preschool, Coronary Circulation, England, Heart Defects, Congenital diagnostic imaging, Heart Defects, Congenital physiopathology, Humans, Materials Testing, Prosthesis Design, Pulmonary Circulation, Radiography, Thrombosis etiology, Time Factors, Treatment Outcome, Cardiac Catheterization instrumentation, Fontan Procedure, Heart Defects, Congenital surgery, Septal Occluder Device, Thrombosis prevention & control
- Abstract
Objective: Most devices devices available for percutaneous closure of Fontan fenestrations tend to be bulky. The aim of this study was to evaluate a low profile custom made device and assess its efficacy and safety., Patients and Methods: A 15 mm PFO star was used as the basis. The following modifications were made: removal of the left disc to reduce thrombogenicity in the left atrium, increase the length of the LA legs from 2 by 15 mm to 3 by 20 mm to prevent dislodgement and later adding a pivot between the left and right umbrella. A partial occluder was made by removing two opposite quadrants from the proximal disk., Results: Device deployment was possible in 93% (63 of 68) patients. In five patients, the device could not be deployed and an alternative device was used. In 45 patients complete closure of the fenestration was obtained and saturations increased from 84% +/- 4% to 95% +/- 2% (P < 001). In 18 high risk patients with suboptimal Fontan circulation, a modified device was used to effect partial occlusion: saturations increased from 79% +/- 7% to 90% +/- 4% (P < 0.001); a residual shunt persisted in most patients for several months. No thrombotic events were recorded during follow-up., Conclusions: The modified PFO star device can safely be deployed in Fontan patients to occlude or restrict flow through a fenestration. It has a low profile with minimal foreign material, is non-obstructive and minimally thrombogenic., (Copyright 2009 Wiley-Liss, Inc.)
- Published
- 2010
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