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To investigate the efficacy of Qingyan dropping pill and drug ice in the treatment of pharyngeal pain after thyroid surgery, and to analyze its effect on related clinical symptoms and sleep quality. The clinical data of 240 patients with pharyngeal pain after thyroid surgery who were treated in the thyroid diagnosis and treatment center of Guangdong Hospital of traditional Chinese medicine from April 2019 to August 2021 were analyzed retrospectively. They were divided into three groups according to different treatment methods, with 80 cases in each group. The control group was drug group, Qingyan dropping pills were given. Experimental group I was ice group, which was gargled with 25% high sugar ice. Experimental group II was medicine ice group, which was given self-made Qingyan dropping pills and medicine ice for gargling. The clinical efficacy of the three groups at 48 h after treatment, TCM syndrome score, deep sleep quality score before treatment and 48 h after treatment and visual analogue scale (VAS) score before treatment, 8 h, 24 h and 48 h after treatment were observed and compared. The total effective rate in experimental group II was significantly higher than that in experimental group I and control group at 48h after treatment (P<0.05). The TCM syndrome score and deep sleep quality score of patients in the three groups at 48 h after treatment were significantly lower than those before treatment(P<0.05), and the VAS score of patients in the three groups at 8 h, 24 h and 48 h after treatment was significantly lower than that before treatment (P<0.05). The TCM syndrome score and deep sleep quality score of experimental group II at 48 h after treatment were significantly lower than those of experimental group I and control group (P<0.05), and the VAS score of experimental group II at 8 h, 24 h and 48 h after treatment was significantly lower than those of experimental group I and control group (P<0.05). : Qingyan dropping pill and drug ice treatment can effectively relieve pharyngeal pain after thyroid surgery and related clinical symptoms, improve the sleep quality of patients, which has a good clinical application value. [ABSTRACT FROM AUTHOR]