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ABSTRACT A 152-day growth experiment was conducted in a recirculated water system to investigate the interaction between vitamins A (retinol) and D (cholecalciferol) on growth and metabolic responses in abalone [...]

The study published in Pediatrics and led by Jonathan Mansbach, MD, USA, at the Children's Hospital Boston, MA, USA; is the most up-to-date analysis of vitamin D levels in 1 [...]

In addition to preventing rickets, vitamin D has recently been found to be protective against many other conditions including breast cancer, osteoporosis, diabetes, arthritis, and depression. Vitamin D can be [...]

Background: Residential children and adolescents with epilepsy may be at increased risk of developing vitamin D deficiency due to long term anticonvulsant (AC) use, reduced sunshine exposure, or insufficient dietary [...]

We investigated whether osteoporosis therapy with alendronate in postmenopausal patients is equally effective in patients who are vitamin D insufficient as in those who are vitamin D sufficient. We found that vitamin D insufficiency is common among patients with low bone density but that vitamin D insufficiency did not impair response to alendronate. INTRODUCTION: Treatment of vitamin D deficiency leads to significant improvements in bone mineral density (BMD); however, whether insufficiency affects BMD's response to bisphosphonate therapy is unknown. METHODS: To determine whether vitamin D insufficiency at initiation of alendronate therapy for low BMD affects treatment efficacy, we used data from 1,000 postmenopausal women randomly selected from the vertebral fracture arm (n = 2,027) of the placebo-controlled Fracture Intervention Trial of alendronate. Participants were randomly assigned to placebo (50%) or alendronate therapy and most (83%) to calcium (500 mg/day) and cholecalciferol (250 IU/day). We measured serum 25-hydroxy vitamin D (25OHD) at enrollment, then categorized baseline vitamin D status according to 25OHD concentration ( __lessthan__/= 10 ng/ml = deficient; > 10 but __lessthan__/= 30 ng/ml = insufficient; > 30 ng/ml = sufficient) and used linear regression to compare the effects of alendronate treatment among these categories. RESULTS AND CONCLUSION: At baseline, participants were vitamin D sufficient (14%), insufficient (83%), and deficient (2%). We found that BMD response to therapy at total hip or spine did not vary by vitamin D status at baseline (p for heterogeneity = 0.6). We determined that vitamin D insufficiency is common among participants with low BMD. However, vitamin D status at initiation of therapy does not affect BMD's response to alendronate, when it is coadministered with cholecalciferol and calcium., Osteoporos Int 2008 Nov 29. [Epub ahead of [...]

A joint study with university investigators funded by the National Institutes of Health has shown that levels of the kind of vitamin D that's critical for building strong bones and [...]

Calcium and vitamin D intake and risk of incident premenstrual syndrome. Bertone-Johnson ER, Hankinson SE, Bendich A, et al. Arch Intern Med 2005;165:1246-1252. BACKGROUND: Premenstrual syndrome (PMS) is one of [...]

Men with higher blood levels of vitamin D have a lower overall risk (45 per cent) of prostate cancer, particularly aggressive prostate cancer, according to a new study presented at [...]

Greater intake of vitamin D may reduce the risk of rheumatoid arthritis (RA) in older women. Calcium has a strong relationship with vitamin D, but no change in the effect [...]

Background: Studies in vitamin D deficient pregnant women have shown that supplementation influences postnatal growth with infants of supplemented mothers being longer and heavier at the age of 1 year [...]

Background: There has been a resurgence of vitamin D deficiency rickets among toddlers in the UK and we have recently observed an increase in the number of adolescents presenting with [...]

Background and Aims: Vitamin D receptor (VDR) maps to a candidate region for inflammatory bowel disease (IBD) and has Apa1, Taq1, and Fok1 coding region polymorphisms. Downstream consequences and clinical [...]