Search

Your search keyword '"Wemer, Johan"' showing total 3 results
Start Over Author "Wemer, Johan" Topic health
3 results on '"Wemer, Johan"'

1. Active renal secretion of NXY-059, a novel neuroprotectant, is mediated via an organic acid transporter

Author

Cheng, Yi-Fang, Strid, Stig, Borga, Olof, Nilsson, Dag, and Wemer, Johan

Subjects
Stroke (Disease) -- Drug therapy -- Research, Drug metabolism -- Research, Central nervous system agents -- Dosage and administration -- Properties -- Research, Health, Drug therapy, Research, Properties, Dosage and administration
Abstract

NXY-059 (disufenton sodium) is a novel, free-radical-trapping neuroprotectant, which, until recently, was in clinical development for the treatment of acute ischemic stroke based on effects seen in experimental animal models. [...]

Published
2007

2. NXY-059 does not affect bleeding time in healthy volunteers: a randomized, double-blind, placebo-controlled, 3-period crossover phase I study

Author

Nilsson, Dag, Wemer, Johan, Cheng, Yi-Fang, Reinholdsson, Ingalill, Englund, Gunnar, Egberg, Nils, and Schulman, Sam

Subjects
Stroke (Disease) -- Care and treatment -- Research, Pharmacokinetics -- Research, Homeostasis -- Research, Health, Care and treatment, Research
Abstract

NXY-059 is a novel free radical-trapping neuroprotectant that reduces infarct size and preserves brain function in animal models of acute ischemic stroke. It is the first neuroprotectant to demonstrate a [...]

Published
2007

3. NXY-059 does not significantly interact with furosemide in healthy volunteers

Author

Strid, Stig, Nilsson, Dag, Borga, Olof, Wemer, Johan, and Grahnen, Anders

Subjects
Nucleoproteins -- Research -- Health aspects, Furosemide -- Dosage and administration -- Research, Stroke (Disease) -- Drug therapy -- Research, Health, Drug therapy, Research, Dosage and administration, Health aspects
Abstract

NXY-059 is a free radical-trapping neuroprotectant that reduces infarct size and preserves brain function in animal models of acute ischemic stroke. Acute ischemic stroke patients receiving NXY-059 may also be [...]

Published
2006

Catalog

Books, media, physical & digital resources
See catalog results