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Introduction: Metabolic syndrome is defined as a cluster of metabolic disorders, which may lead to type II diabetes and cardiovascular diseases. Promotion of healthy lifestyle and use of herbal supplements with anthocyanin and phenols are recommended for the treatment of metabolic syndrome. The present study aimed to investigate the effects of eight weeks of combined aerobic and resistance exercises and pomegranate concentrate consumption on the levels of HbA1c and C-peptide in women with metabolic syndrome. Methods: This study was conducted on 30 middle-aged­ women with metabolic syndrome, who were randomly assigned to two groups of exercise (E; n=15) and exercise with pomegranate concentrate (EPC; n=15). The exercise protocol was conducted at 60-80% intensity of the maximal heart rate and 60-80% of one-repetition maximum. Data analysis was performed in SPSS version 20 at the significance level of P≤0.05. Results: HbA1C levels significantly reduced in the EPC group (P0.05). In addition, the within-group comparison indicated no significant changes in the C-peptide levels in the E and EPC groups (P>0.05). Conclusion: According to the results, regular physical exercises along with the consumption of pomegranate concentrate could be effective in reducing HBA1c. Improving a number of metabolic syndrome indices (e.g., insulin resistance) could prevent the complications of metabolic syndrome in middle-aged women.

Introduction: Metabolic syndrome is defined as a cluster of metabolic disorders, which may lead to type II diabetes and cardiovascular diseases. Promotion of healthy lifestyle and use of herbal supplements with anthocyanin and phenols are recommended for the treatment of metabolic syndrome. The present study aimed to investigate the effects of eight weeks of combined aerobic and resistance exercises and pomegranate concentrate consumption on the levels of HbA1c and Cpeptide in women with metabolic syndrome. Methods: This study was conducted on 30 middle-aged women with metabolic syndrome, who were randomly assigned to two groups of exercise (E; n=15) and exercise with pomegranate concentrate (EPC; n=15). The exercise protocol was conducted at 60-80% intensity of the maximal heart rate and 60-80% of one-repetition maximum. Data analysis was performed in SPSS version 20 at the significance level of P=0.05. Results: HbA1C levels significantly reduced in the EPC group (P<0.05), while no significant difference was observed between the groups in terms of the C-peptide and HbA1C levels (P>0.05). In addition, the within-group comparison indicated no significant changes in the C-peptide levels in the E and EPC groups (P>0.05). Conclusion: According to the results, regular physical exercises along with the consumption of pomegranate concentrate could be effective in reducing HBA1c. Improving a number of metabolic syndrome indices (e.g., insulin resistance) could prevent the complications of metabolic syndrome in middle-aged women. [ABSTRACT FROM AUTHOR]

Introduction: Irisin is a myokine released from a membrane protein FNDC5 and has positive effects on carbohydrate metabolism. The aim of this study was to compare the effect of two different intensities of combined training on serum irisin, FBS, HbA1c and insulin resistance. Materials and Methods: 26 patients with type 2 diabetes mellitus were divided into 3 groups, intense and moderate combined exercise and control group. The training groups participated in combination exercises with high or moderate intensity for 8 weeks. Exercise aerobic moderate intensity performed with 70 to 89% of HRmax, 75 minutes per week. Addition 2 day strength training with elastic band. Moderate exercise aerobic exercises were performed at 55-69% of HRmax, 150 minutes per week. and resistance training two days a week with elastic band. Blood samples were taken before exercise and 48 hours after the last session. Results: Combined exercise leading to increased irisin, decrease fasting blood glucose, HbA1c, and decreased insulin resistance in both experimental groups (P<0.05). Although the increase irisin hormone in intense training group was more than moderate group, but there was no significant difference in fasting blood glucose, HbA1c and insulin resistance between the two groups (P<0.05). Conclusion: Combined exercises are beneficial for increasing the level of irisin, reducing fasting blood glucose, HbA1c and decreasing insulin resistance, and therefore controlling diabetes. Moderate combination exercises can be used to improve glycemic conditions as an efficient method. [ABSTRACT FROM AUTHOR]