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Your search keyword '"M. Yoshizaki"' showing total 5 results
Start Over Author "M. Yoshizaki" Topic glycosides
5 results on '"M. Yoshizaki"'

1. A new tomato pregnane glycoside from the overripe fruits.

Author

Fujiwara Y, Yoshizaki M, Matsushita S, Yahara S, Yae E, Ikeda T, Ono M, and Nohara T

Subjects
Glycosides chemistry, Pregnanes chemistry, Fruit, Glycosides isolation & purification, Solanum lycopersicum, Pregnanes isolation & purification
Abstract

A new pregnane glycoside has been isolated from the overripe fruits of Cherry tomato (Mini tomato), Lycopersicon esculentum var. cerasiforme (DUNAL) ALEF. The structure was determined to be 3-O-beta-lycotetraosyl 3beta-hydroxy-5alpha-pregn-16-en-20-one on the basis of spectroscopic analysis. The seasonal variation of the tomato saponin is discussed.

Published
2005
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2. Blocking effects of blended paeoniflorin or its related compounds with glycyrrhizin on neuromuscular junctions in frog and mouse.

Author

Kimura M, Kimura I, Takahashi K, Muroi M, Yoshizaki M, Kanaoka M, and Kitagawa I

Subjects
Animals, Drug Interactions, Glycyrrhetinic Acid pharmacology, Glycyrrhizic Acid, In Vitro Techniques, Male, Mice, Monoterpenes, Neuromuscular Depolarizing Agents pharmacology, Phrenic Nerve drug effects, Ranidae, Sciatic Nerve drug effects, Species Specificity, Time Factors, Anti-Inflammatory Agents pharmacology, Benzoates, Bridged-Ring Compounds, Glucosides pharmacology, Glycosides pharmacology, Glycyrrhetinic Acid analogs & derivatives, Neuromuscular Blocking Agents
Abstract

The combined effects of paeoniflorin (PF), a main component of paeony roots, and glycyrrhizin (GLR), a main component of licorice roots, were investigated on isolated sciatic nerve-sartorius muscle preparations in frogs, or on isolated or in situ phrenic nerve-diaphragm muscle preparations in mice, intending to explain the effects of "Shakuyaku-Kanzô-Tô, composed of both these Chinese drugs, on clinical neuropathy. PF and GLR used together blocked indirectly stimulated twitchings at concentrations which when used alone induced no blocking effects. PF and GLR at a combining ratio of 1:2 (weight concentrations) corresponding to the amounts contained in "Shakuyaku-Kanzô-Tô, was more potent than when they were used at the ratio of 1:1 or 2:1. The synergistic effects induced by GLR were also confirmed for the other components, paeoniflorigenone or oxypaeoniflorin, which are contained in paeony roots, and for succinylcholine. The blocking effect of d-tubocurarine were not increased by GLR. Concludedly, PF and GLR were found to cause the pharmacological blend effect. The two combined compounds were mainly therapeutic components in "Shakuyaku-Kanzô-Tô".

Published
1984
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3. Chemical and pharmaceutical studies on medicinal plants in Paraguay. Geraniin, an angiotensin-converting enzyme inhibitor from "paraparai mi," Phyllanthus niruri.

Author

Ueno H, Horie S, Nishi Y, Shogawa H, Kawasaki M, Suzuki S, Hayashi T, Arisawa M, Shimizu M, and Yoshizaki M

Subjects
Angiotensin-Converting Enzyme Inhibitors pharmacology, Glucosides pharmacology, Magnetic Resonance Spectroscopy, Paraguay, Spectrophotometry, Ultraviolet, Angiotensin-Converting Enzyme Inhibitors isolation & purification, Glucosides isolation & purification, Glycosides isolation & purification, Hydrolyzable Tannins, Plants, Medicinal analysis, Tannins
Published
1988
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4. [Fundamental studies on the evaluation of the crude drugs. V. Quantitative analysis of constituents in crude drugs by rod-thin-layer chromatography with FID. (2). Determination of paeoniflorin and albiflorin in paeony roots (author's transl)].

Author

Yoshizaki M, Tomimori T, Yoshioka S, and Namba T

Subjects
Chromatography, Thin Layer, Flame Ionization, Glycosides analysis, Medicine, Chinese Traditional, Medicine, East Asian Traditional, Plants, Medicinal analysis
Published
1977
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5. Blocking effects of blended paeoniflorin or its related compounds with glycyrrhizin on neuromuscular junctions in frog and mouse

Author

M, Kimura, I, Kimura, K, Takahashi, M, Muroi, M, Yoshizaki, M, Kanaoka, and I, Kitagawa

Subjects
Bridged-Ring Compounds, Male, Time Factors, Ranidae, Anti-Inflammatory Agents, In Vitro Techniques, Glycyrrhizic Acid, Benzoates, Sciatic Nerve, Phrenic Nerve, Mice, Glucosides, Species Specificity, Neuromuscular Depolarizing Agents, Monoterpenes, Animals, Glycyrrhetinic Acid, Drug Interactions, Glycosides, Neuromuscular Blocking Agents
Abstract

The combined effects of paeoniflorin (PF), a main component of paeony roots, and glycyrrhizin (GLR), a main component of licorice roots, were investigated on isolated sciatic nerve-sartorius muscle preparations in frogs, or on isolated or in situ phrenic nerve-diaphragm muscle preparations in mice, intending to explain the effects of "Shakuyaku-Kanzô-Tô, composed of both these Chinese drugs, on clinical neuropathy. PF and GLR used together blocked indirectly stimulated twitchings at concentrations which when used alone induced no blocking effects. PF and GLR at a combining ratio of 1:2 (weight concentrations) corresponding to the amounts contained in "Shakuyaku-Kanzô-Tô, was more potent than when they were used at the ratio of 1:1 or 2:1. The synergistic effects induced by GLR were also confirmed for the other components, paeoniflorigenone or oxypaeoniflorin, which are contained in paeony roots, and for succinylcholine. The blocking effect of d-tubocurarine were not increased by GLR. Concludedly, PF and GLR were found to cause the pharmacological blend effect. The two combined compounds were mainly therapeutic components in "Shakuyaku-Kanzô-Tô".

Published
1984

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