1. Diabetic scleredema: a case report and biochemical analysis for glycosaminoglycans.
- Author
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Kobayashi T, Yamasaki Y, and Watanabe T
- Subjects
- Chondroitin Sulfates analysis, Dermatan Sulfate analysis, Female, Fibrosis, Humans, Hyaluronic Acid analysis, Middle Aged, Mucinoses etiology, Mucinoses metabolism, Mucinoses pathology, Mucins analysis, Scleredema Adultorum metabolism, Scleredema Adultorum pathology, Skin pathology, Diabetes Complications, Glycosaminoglycans analysis, Scleredema Adultorum etiology, Skin metabolism
- Abstract
We report a patient with the typical lesions of diabetic scleredema. Histological findings of the involved skin were thickening of the dermis, depositions of mucins, and fibrosis. Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis. Mucinous materials were composed of hyaluronic acid.
- Published
- 1997
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