1. Tonsillar Kaposi Sarcoma in a Patient with Membranous Glomerulonephritis on Immunosuppressive Therapy
- Author
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Khaled El-Merhi, Nabeel Al-Brahim, Mahmoud S Ahmad, and Ashraf H Zaki
- Subjects
Adult ,Male ,Pathology ,medicine.medical_specialty ,Prednisolone ,medicine.medical_treatment ,Tonsillar Neoplasms ,CD34 ,Glomerulonephritis, Membranous ,Stain ,Immunocompromised Host ,Humans ,Medicine ,Sarcoma, Kaposi ,business.industry ,virus diseases ,Immunosuppression ,Glomerulonephritis ,Malignant Vascular Neoplasm ,medicine.disease ,medicine.anatomical_structure ,Otorhinolaryngology ,Tonsil ,Cyclosporine ,Sarcoma ,business ,Immunosuppressive Agents ,medicine.drug - Abstract
Kaposi sarcoma is a malignant vascular neoplasm uncommonly seen in immunosuppressed patients. Herein we report an unusual case of tonsillar Kaposi sarcoma in a patient with membranous glomerulonephritis treated with prednisolone and cyclosporine. The patient presented after 10 months of starting the treatment with a tonsillar mass. Histological examination was typical of monomorphic spindle cell proliferation with slit-like vascular channels. The tumor cells expressed CD34, D2-40 and positive nuclear stain for HHV-8. Kaposi sarcoma is associated with immunosuppression and rarely occurs in the tonsil. Clinicians should be aware of this rare presentation of Kaposi sarcoma.
- Published
- 2013
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