Search

Your search keyword '"Colquhoun, S."' showing total 4 results
Start Over Author "Colquhoun, S." Topic global health
4 results on '"Colquhoun, S."'

1. Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

Author

Murray CJ, Vos T, Lozano R, Naghavi M, Flaxman AD, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black JA, Blencowe H, Blore JD, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha TS, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke CM, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter CE, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng AT, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Des Jarlais DC, Dharmaratne SD, Dherani M, Diaz-Torne C, Dolk H, Dorsey ER, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali SE, Erskine H, Erwin PJ, Espindola P, Ewoigbokhan SE, Farzadfar F, Feigin V, Felson DT, Ferrari A, Ferri CP, Fèvre EM, Finucane MM, Flaxman S, Flood L, Foreman K, Forouzanfar MH, Fowkes FG, Fransen M, Freeman MK, Gabbe BJ, Gabriel SE, Gakidou E, Ganatra HA, Garcia B, Gaspari F, Gillum RF, Gmel G, Gonzalez-Medina D, Gosselin R, Grainger R, Grant B, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa YA, Hall W, Haring D, Haro JM, Harrison JE, Havmoeller R, Hay RJ, Higashi H, Hill C, Hoen B, Hoffman H, Hotez PJ, Hoy D, Huang JJ, Ibeanusi SE, Jacobsen KH, James SL, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas JB, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo JP, King CH, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Laden F, Lalloo R, Laslett LL, Lathlean T, Leasher JL, Lee YY, Leigh J, Levinson D, Lim SS, Limb E, Lin JK, Lipnick M, Lipshultz SE, Liu W, Loane M, Ohno SL, Lyons R, Mabweijano J, MacIntyre MF, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis DJ, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGill N, McGrath J, Medina-Mora ME, Meltzer M, Mensah GA, Merriman TR, Meyer AC, Miglioli V, Miller M, Miller TR, Mitchell PB, Mock C, Mocumbi AO, Moffitt TE, Mokdad AA, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch ME, Mwaniki MK, Naidoo K, Nair MN, Naldi L, Narayan KM, Nelson PK, Nelson RG, Nevitt MC, Newton CR, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer SB, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian JD, Rivero AP, Patten SB, Pearce N, Padilla RP, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips MR, Pierce K, Pion S, Polanczyk GV, Polinder S, Pope CA 3rd, Popova S, Porrini E, Pourmalek F, Prince M, Pullan RL, Ramaiah KD, Ranganathan D, Razavi H, Regan M, Rehm JT, Rein DB, Remuzzi G, Richardson K, Rivara FP, Roberts T, Robinson C, De Leòn FR, Ronfani L, Room R, Rosenfeld LC, Rushton L, Sacco RL, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel DC, Scott JG, Segui-Gomez M, Shahraz S, Shepard DS, Shin H, Shivakoti R, Singh D, Singh GM, Singh JA, Singleton J, Sleet DA, Sliwa K, Smith E, Smith JL, Stapelberg NJ, Steer A, Steiner T, Stolk WA, Stovner LJ, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor HR, Taylor JA, Taylor WJ, Thomas B, Thomson WM, Thurston GD, Tleyjeh IM, Tonelli M, Towbin JA, Truelsen T, Tsilimbaris MK, Ubeda C, Undurraga EA, van der Werf MJ, van Os J, Vavilala MS, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall DJ, Weinstock MA, Weintraub R, Weisskopf MG, Weissman MM, White RA, Whiteford H, Wiebe N, Wiersma ST, Wilkinson JD, Williams HC, Williams SR, Witt E, Wolfe F, Woolf AD, Wulf S, Yeh PH, Zaidi AK, Zheng ZJ, Zonies D, Lopez AD, AlMazroa MA, and Memish ZA

Subjects
Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Prevalence, Sex Factors, Young Adult, Global Health statistics & numerical data, Health Status, Quality-Adjusted Life Years, Wounds and Injuries epidemiology
Abstract

Background: Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of ill-health. The 1990 Global Burden of Disease study proposed disability-adjusted life years (DALYs) to measure disease burden. No comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study. We aimed to calculate disease burden worldwide and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time., Methods: We calculated DALYs as the sum of years of life lost (YLLs) and years lived with disability (YLDs). DALYs were calculated for 291 causes, 20 age groups, both sexes, and for 187 countries, and aggregated to regional and global estimates of disease burden for three points in time with strictly comparable definitions and methods. YLLs were calculated from age-sex-country-time-specific estimates of mortality by cause, with death by standardised lost life expectancy at each age. YLDs were calculated as prevalence of 1160 disabling sequelae, by age, sex, and cause, and weighted by new disability weights for each health state. Neither YLLs nor YLDs were age-weighted or discounted. Uncertainty around cause-specific DALYs was calculated incorporating uncertainty in levels of all-cause mortality, cause-specific mortality, prevalence, and disability weights., Findings: Global DALYs remained stable from 1990 (2·503 billion) to 2010 (2·490 billion). Crude DALYs per 1000 decreased by 23% (472 per 1000 to 361 per 1000). An important shift has occurred in DALY composition with the contribution of deaths and disability among children (younger than 5 years of age) declining from 41% of global DALYs in 1990 to 25% in 2010. YLLs typically account for about half of disease burden in more developed regions (high-income Asia Pacific, western Europe, high-income North America, and Australasia), rising to over 80% of DALYs in sub-Saharan Africa. In 1990, 47% of DALYs worldwide were from communicable, maternal, neonatal, and nutritional disorders, 43% from non-communicable diseases, and 10% from injuries. By 2010, this had shifted to 35%, 54%, and 11%, respectively. Ischaemic heart disease was the leading cause of DALYs worldwide in 2010 (up from fourth rank in 1990, increasing by 29%), followed by lower respiratory infections (top rank in 1990; 44% decline in DALYs), stroke (fifth in 1990; 19% increase), diarrhoeal diseases (second in 1990; 51% decrease), and HIV/AIDS (33rd in 1990; 351% increase). Major depressive disorder increased from 15th to 11th rank (37% increase) and road injury from 12th to 10th rank (34% increase). Substantial heterogeneity exists in rankings of leading causes of disease burden among regions., Interpretation: Global disease burden has continued to shift away from communicable to non-communicable diseases and from premature death to years lived with disability. In sub-Saharan Africa, however, many communicable, maternal, neonatal, and nutritional disorders remain the dominant causes of disease burden. The rising burden from mental and behavioural disorders, musculoskeletal disorders, and diabetes will impose new challenges on health systems. Regional heterogeneity highlights the importance of understanding local burden of disease and setting goals and targets for the post-2015 agenda taking such patterns into account. Because of improved definitions, methods, and data, these results for 1990 and 2010 supersede all previously published Global Burden of Disease results., Funding: Bill & Melinda Gates Foundation., (Copyright © 2012 Elsevier Ltd. All rights reserved.)

Published
2012
Full Text
View/download PDF

2. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

Author

Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, Bernabé E, Bhalla K, Bhandari B, Bikbov B, Bin Abdulhak A, Birbeck G, Black JA, Blencowe H, Blore JD, Blyth F, Bolliger I, Bonaventure A, Boufous S, Bourne R, Boussinesq M, Braithwaite T, Brayne C, Bridgett L, Brooker S, Brooks P, Brugha TS, Bryan-Hancock C, Bucello C, Buchbinder R, Buckle G, Budke CM, Burch M, Burney P, Burstein R, Calabria B, Campbell B, Canter CE, Carabin H, Carapetis J, Carmona L, Cella C, Charlson F, Chen H, Cheng AT, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahiya M, Dahodwala N, Damsere-Derry J, Danaei G, Davis A, De Leo D, Degenhardt L, Dellavalle R, Delossantos A, Denenberg J, Derrett S, Des Jarlais DC, Dharmaratne SD, Dherani M, Diaz-Torne C, Dolk H, Dorsey ER, Driscoll T, Duber H, Ebel B, Edmond K, Elbaz A, Ali SE, Erskine H, Erwin PJ, Espindola P, Ewoigbokhan SE, Farzadfar F, Feigin V, Felson DT, Ferrari A, Ferri CP, Fèvre EM, Finucane MM, Flaxman S, Flood L, Foreman K, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabbe BJ, Gabriel SE, Gakidou E, Ganatra HA, Garcia B, Gaspari F, Gillum RF, Gmel G, Gosselin R, Grainger R, Groeger J, Guillemin F, Gunnell D, Gupta R, Haagsma J, Hagan H, Halasa YA, Hall W, Haring D, Haro JM, Harrison JE, Havmoeller R, Hay RJ, Higashi H, Hill C, Hoen B, Hoffman H, Hotez PJ, Hoy D, Huang JJ, Ibeanusi SE, Jacobsen KH, James SL, Jarvis D, Jasrasaria R, Jayaraman S, Johns N, Jonas JB, Karthikeyan G, Kassebaum N, Kawakami N, Keren A, Khoo JP, King CH, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lalloo R, Laslett LL, Lathlean T, Leasher JL, Lee YY, Leigh J, Lim SS, Limb E, Lin JK, Lipnick M, Lipshultz SE, Liu W, Loane M, Ohno SL, Lyons R, Ma J, Mabweijano J, MacIntyre MF, Malekzadeh R, Mallinger L, Manivannan S, Marcenes W, March L, Margolis DJ, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGill N, McGrath J, Medina-Mora ME, Meltzer M, Mensah GA, Merriman TR, Meyer AC, Miglioli V, Miller M, Miller TR, Mitchell PB, Mocumbi AO, Moffitt TE, Mokdad AA, Monasta L, Montico M, Moradi-Lakeh M, Moran A, Morawska L, Mori R, Murdoch ME, Mwaniki MK, Naidoo K, Nair MN, Naldi L, Narayan KM, Nelson PK, Nelson RG, Nevitt MC, Newton CR, Nolte S, Norman P, Norman R, O'Donnell M, O'Hanlon S, Olives C, Omer SB, Ortblad K, Osborne R, Ozgediz D, Page A, Pahari B, Pandian JD, Rivero AP, Patten SB, Pearce N, Padilla RP, Perez-Ruiz F, Perico N, Pesudovs K, Phillips D, Phillips MR, Pierce K, Pion S, Polanczyk GV, Polinder S, Pope CA 3rd, Popova S, Porrini E, Pourmalek F, Prince M, Pullan RL, Ramaiah KD, Ranganathan D, Razavi H, Regan M, Rehm JT, Rein DB, Remuzzi G, Richardson K, Rivara FP, Roberts T, Robinson C, De Leòn FR, Ronfani L, Room R, Rosenfeld LC, Rushton L, Sacco RL, Saha S, Sampson U, Sanchez-Riera L, Sanman E, Schwebel DC, Scott JG, Segui-Gomez M, Shahraz S, Shepard DS, Shin H, Shivakoti R, Singh D, Singh GM, Singh JA, Singleton J, Sleet DA, Sliwa K, Smith E, Smith JL, Stapelberg NJ, Steer A, Steiner T, Stolk WA, Stovner LJ, Sudfeld C, Syed S, Tamburlini G, Tavakkoli M, Taylor HR, Taylor JA, Taylor WJ, Thomas B, Thomson WM, Thurston GD, Tleyjeh IM, Tonelli M, Towbin JA, Truelsen T, Tsilimbaris MK, Ubeda C, Undurraga EA, van der Werf MJ, van Os J, Vavilala MS, Venketasubramanian N, Wang M, Wang W, Watt K, Weatherall DJ, Weinstock MA, Weintraub R, Weisskopf MG, Weissman MM, White RA, Whiteford H, Wiersma ST, Wilkinson JD, Williams HC, Williams SR, Witt E, Wolfe F, Woolf AD, Wulf S, Yeh PH, Zaidi AK, Zheng ZJ, Zonies D, Lopez AD, Murray CJ, AlMazroa MA, and Memish ZA

Subjects
Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Incidence, Infant, Infant, Newborn, Male, Middle Aged, Prevalence, Sex Factors, Young Adult, Global Health statistics & numerical data, Health Status, Quality-Adjusted Life Years, Wounds and Injuries epidemiology
Abstract

Background: Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health. The Global Burden of Disease (GBD) studies done in 1990 and 2000 have been the only studies to quantify non-fatal health outcomes across an exhaustive set of disorders at the global and regional level. Neither effort quantified uncertainty in prevalence or years lived with disability (YLDs)., Methods: Of the 291 diseases and injuries in the GBD cause list, 289 cause disability. For 1160 sequelae of the 289 diseases and injuries, we undertook a systematic analysis of prevalence, incidence, remission, duration, and excess mortality. Sources included published studies, case notification, population-based cancer registries, other disease registries, antenatal clinic serosurveillance, hospital discharge data, ambulatory care data, household surveys, other surveys, and cohort studies. For most sequelae, we used a Bayesian meta-regression method, DisMod-MR, designed to address key limitations in descriptive epidemiological data, including missing data, inconsistency, and large methodological variation between data sources. For some disorders, we used natural history models, geospatial models, back-calculation models (models calculating incidence from population mortality rates and case fatality), or registration completeness models (models adjusting for incomplete registration with health-system access and other covariates). Disability weights for 220 unique health states were used to capture the severity of health loss. YLDs by cause at age, sex, country, and year levels were adjusted for comorbidity with simulation methods. We included uncertainty estimates at all stages of the analysis., Findings: Global prevalence for all ages combined in 2010 across the 1160 sequelae ranged from fewer than one case per 1 million people to 350,000 cases per 1 million people. Prevalence and severity of health loss were weakly correlated (correlation coefficient -0·37). In 2010, there were 777 million YLDs from all causes, up from 583 million in 1990. The main contributors to global YLDs were mental and behavioural disorders, musculoskeletal disorders, and diabetes or endocrine diseases. The leading specific causes of YLDs were much the same in 2010 as they were in 1990: low back pain, major depressive disorder, iron-deficiency anaemia, neck pain, chronic obstructive pulmonary disease, anxiety disorders, migraine, diabetes, and falls. Age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010. Regional patterns of the leading causes of YLDs were more similar compared with years of life lost due to premature mortality. Neglected tropical diseases, HIV/AIDS, tuberculosis, malaria, and anaemia were important causes of YLDs in sub-Saharan Africa., Interpretation: Rates of YLDs per 100,000 people have remained largely constant over time but rise steadily with age. Population growth and ageing have increased YLD numbers and crude rates over the past two decades. Prevalences of the most common causes of YLDs, such as mental and behavioural disorders and musculoskeletal disorders, have not decreased. Health systems will need to address the needs of the rising numbers of individuals with a range of disorders that largely cause disability but not mortality. Quantification of the burden of non-fatal health outcomes will be crucial to understand how well health systems are responding to these challenges. Effective and affordable strategies to deal with this rising burden are an urgent priority for health systems in most parts of the world., Funding: Bill & Melinda Gates Foundation., (Copyright © 2012 Elsevier Ltd. All rights reserved.)

Published
2012
Full Text
View/download PDF

3. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.

Author

Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, Burney P, Carapetis J, Chen H, Chou D, Chugh SS, Coffeng LE, Colan SD, Colquhoun S, Colson KE, Condon J, Connor MD, Cooper LT, Corriere M, Cortinovis M, de Vaccaro KC, Couser W, Cowie BC, Criqui MH, Cross M, Dabhadkar KC, Dahodwala N, De Leo D, Degenhardt L, Delossantos A, Denenberg J, Des Jarlais DC, Dharmaratne SD, Dorsey ER, Driscoll T, Duber H, Ebel B, Erwin PJ, Espindola P, Ezzati M, Feigin V, Flaxman AD, Forouzanfar MH, Fowkes FG, Franklin R, Fransen M, Freeman MK, Gabriel SE, Gakidou E, Gaspari F, Gillum RF, Gonzalez-Medina D, Halasa YA, Haring D, Harrison JE, Havmoeller R, Hay RJ, Hoen B, Hotez PJ, Hoy D, Jacobsen KH, James SL, Jasrasaria R, Jayaraman S, Johns N, Karthikeyan G, Kassebaum N, Keren A, Khoo JP, Knowlton LM, Kobusingye O, Koranteng A, Krishnamurthi R, Lipnick M, Lipshultz SE, Ohno SL, Mabweijano J, MacIntyre MF, Mallinger L, March L, Marks GB, Marks R, Matsumori A, Matzopoulos R, Mayosi BM, McAnulty JH, McDermott MM, McGrath J, Mensah GA, Merriman TR, Michaud C, Miller M, Miller TR, Mock C, Mocumbi AO, Mokdad AA, Moran A, Mulholland K, Nair MN, Naldi L, Narayan KM, Nasseri K, Norman P, O'Donnell M, Omer SB, Ortblad K, Osborne R, Ozgediz D, Pahari B, Pandian JD, Rivero AP, Padilla RP, Perez-Ruiz F, Perico N, Phillips D, Pierce K, Pope CA 3rd, Porrini E, Pourmalek F, Raju M, Ranganathan D, Rehm JT, Rein DB, Remuzzi G, Rivara FP, Roberts T, De León FR, Rosenfeld LC, Rushton L, Sacco RL, Salomon JA, Sampson U, Sanman E, Schwebel DC, Segui-Gomez M, Shepard DS, Singh D, Singleton J, Sliwa K, Smith E, Steer A, Taylor JA, Thomas B, Tleyjeh IM, Towbin JA, Truelsen T, Undurraga EA, Venketasubramanian N, Vijayakumar L, Vos T, Wagner GR, Wang M, Wang W, Watt K, Weinstock MA, Weintraub R, Wilkinson JD, Woolf AD, Wulf S, Yeh PH, Yip P, Zabetian A, Zheng ZJ, Lopez AD, Murray CJ, AlMazroa MA, and Memish ZA

Subjects
Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Middle Aged, Sex Factors, Young Adult, Cause of Death trends, Global Health statistics & numerical data, Mortality trends
Abstract

Background: Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates. In the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010), we aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex., Methods: We attempted to identify all available data on causes of death for 187 countries from 1980 to 2010 from vital registration, verbal autopsy, mortality surveillance, censuses, surveys, hospitals, police records, and mortuaries. We assessed data quality for completeness, diagnostic accuracy, missing data, stochastic variations, and probable causes of death. We applied six different modelling strategies to estimate cause-specific mortality trends depending on the strength of the data. For 133 causes and three special aggregates we used the Cause of Death Ensemble model (CODEm) approach, which uses four families of statistical models testing a large set of different models using different permutations of covariates. Model ensembles were developed from these component models. We assessed model performance with rigorous out-of-sample testing of prediction error and the validity of 95% UIs. For 13 causes with low observed numbers of deaths, we developed negative binomial models with plausible covariates. For 27 causes for which death is rare, we modelled the higher level cause in the cause hierarchy of the GBD 2010 and then allocated deaths across component causes proportionately, estimated from all available data in the database. For selected causes (African trypanosomiasis, congenital syphilis, whooping cough, measles, typhoid and parathyroid, leishmaniasis, acute hepatitis E, and HIV/AIDS), we used natural history models based on information on incidence, prevalence, and case-fatality. We separately estimated cause fractions by aetiology for diarrhoea, lower respiratory infections, and meningitis, as well as disaggregations by subcause for chronic kidney disease, maternal disorders, cirrhosis, and liver cancer. For deaths due to collective violence and natural disasters, we used mortality shock regressions. For every cause, we estimated 95% UIs that captured both parameter estimation uncertainty and uncertainty due to model specification where CODEm was used. We constrained cause-specific fractions within every age-sex group to sum to total mortality based on draws from the uncertainty distributions., Findings: In 2010, there were 52·8 million deaths globally. At the most aggregate level, communicable, maternal, neonatal, and nutritional causes were 24·9% of deaths worldwide in 2010, down from 15·9 million (34·1%) of 46·5 million in 1990. This decrease was largely due to decreases in mortality from diarrhoeal disease (from 2·5 to 1·4 million), lower respiratory infections (from 3·4 to 2·8 million), neonatal disorders (from 3·1 to 2·2 million), measles (from 0·63 to 0·13 million), and tetanus (from 0·27 to 0·06 million). Deaths from HIV/AIDS increased from 0·30 million in 1990 to 1·5 million in 2010, reaching a peak of 1·7 million in 2006. Malaria mortality also rose by an estimated 19·9% since 1990 to 1·17 million deaths in 2010. Tuberculosis killed 1·2 million people in 2010. Deaths from non-communicable diseases rose by just under 8 million between 1990 and 2010, accounting for two of every three deaths (34·5 million) worldwide by 2010. 8 million people died from cancer in 2010, 38% more than two decades ago; of these, 1·5 million (19%) were from trachea, bronchus, and lung cancer. Ischaemic heart disease and stroke collectively killed 12·9 million people in 2010, or one in four deaths worldwide, compared with one in five in 1990; 1·3 million deaths were due to diabetes, twice as many as in 1990. The fraction of global deaths due to injuries (5·1 million deaths) was marginally higher in 2010 (9·6%) compared with two decades earlier (8·8%). This was driven by a 46% rise in deaths worldwide due to road traffic accidents (1·3 million in 2010) and a rise in deaths from falls. Ischaemic heart disease, stroke, chronic obstructive pulmonary disease (COPD), lower respiratory infections, lung cancer, and HIV/AIDS were the leading causes of death in 2010. Ischaemic heart disease, lower respiratory infections, stroke, diarrhoeal disease, malaria, and HIV/AIDS were the leading causes of years of life lost due to premature mortality (YLLs) in 2010, similar to what was estimated for 1990, except for HIV/AIDS and preterm birth complications. YLLs from lower respiratory infections and diarrhoea decreased by 45-54% since 1990; ischaemic heart disease and stroke YLLs increased by 17-28%. Regional variations in leading causes of death were substantial. Communicable, maternal, neonatal, and nutritional causes still accounted for 76% of premature mortality in sub-Saharan Africa in 2010. Age standardised death rates from some key disorders rose (HIV/AIDS, Alzheimer's disease, diabetes mellitus, and chronic kidney disease in particular), but for most diseases, death rates fell in the past two decades; including major vascular diseases, COPD, most forms of cancer, liver cirrhosis, and maternal disorders. For other conditions, notably malaria, prostate cancer, and injuries, little change was noted., Interpretation: Population growth, increased average age of the world's population, and largely decreasing age-specific, sex-specific, and cause-specific death rates combine to drive a broad shift from communicable, maternal, neonatal, and nutritional causes towards non-communicable diseases. Nevertheless, communicable, maternal, neonatal, and nutritional causes remain the dominant causes of YLLs in sub-Saharan Africa. Overlaid on this general pattern of the epidemiological transition, marked regional variation exists in many causes, such as interpersonal violence, suicide, liver cancer, diabetes, cirrhosis, Chagas disease, African trypanosomiasis, melanoma, and others. Regional heterogeneity highlights the importance of sound epidemiological assessments of the causes of death on a regular basis., Funding: Bill & Melinda Gates Foundation., (Copyright © 2012 Elsevier Ltd. All rights reserved.)

Published
2012
Full Text
View/download PDF

4. Global injury morbidity and mortality from 1990 to 2017 : results from the Global Burden of Disease Study 2017

Author

Giulio Castelpietra, Feng Sha, Khalid A Altirkawi, Seyedeh Zahra Masoumi, Gebreamlak Gebremedhn Gebremeskel, Ahmad Daryani, Ibrahim Abdollahpour, Simon I. Hay, Deborah Carvalho Malta, Erin B Hamilton, Kate E. LeGrand, Nikolay Ivanovich Briko, Ana-Laura Manda, Aziz Eftekhari, Irfan Ullah, Seth Christopher Yaw Appiah, Zichen Liu, Maida Umar, Shaimaa I. El-Jaafary, Marina Pinheiro, Farhad Ghamari, Milad Mohammadoo-Khorasani, Rajaram Yadav, Syed Mohamed Aljunid, Ramesh Holla, Farzad Jalilian, Jacek Jerzy Jozwiak, Omar Mukhtar Salman, Bayew Kelkay, Tanuj Kanchan, Irina Filip, Michael R. Phillips, Hamid Reza Tohidinik, Demelash Abewa Elemineh, Reza Malekzadeh, Tomasz Miazgowski, Diana Silva, Samath D Dharmaratne, Eleonora Dubljanin, Fatemeh Zare, Jasvinder A. Singh, Hagazi Gebremedhin Kassaye, Nathaniel J Henry, Venkatesh Maled, Girikumar Kumaresh, Alireza Rafiei, Zhi-Jiang Zhang, Arielle Wilder Eagan, Merhawi Gebremedhin Tekle, Gholamreza Roshandel, Jeevan Pereira, Tinuke O Olagunju, Olatunde Aremu, Mohammad Zamani, Mu'awiyyah Babale Sufiyan, Lidia Morawska, Bayisa Abdissa Baye, Eduarda Fernandes, Feleke Mekonnen Demeke, Beriwan Abdulqadir Ali, Ibrahim A Khalil, Hafte Kahsay Kebede, Songhomitra Panda-Jonas, Yuichiro Yano, Haileab Fekadu Wolde, Antonio Maria Borzì, Delia Hendrie, Azeem Majeed, Vahid Rashedi, Mehran Shams-Beyranvand, Ilais Moreno Velásquez, Derrick A Bennett, Roba Khundkar, Mohammed Madadin, Biniyam Sahiledengle Geberemariyam, Parul Puri, Lidia Sanchez Riera, Yetunde O. John-Akinola, Jennifer Rickard, Saeed Shahabi, Tiffany K. Gill, Jemal Abdu Mohammed, Alessandra C. Goulart, Mohiuddin Ahsanul Kabir Chowdhury, Roya Safari-Faramani, Pawan Faris, Farhad Moradpour, Guilherme Borges, Sadia Bibi, Bartosz Miazgowski, Wubalem Fekadu, Rakhi Dandona, Ali Reza Soltanian, Alaa Badawi, Amir Hasanzadeh, Hassan Haghparast Bidgoli, Carlos A Castañeda-Orjuela, Morteza Arab-Zozani, Vinay Nangia, Gaurav Gupta, Farkhonde Salehi, Isabela M. Benseñor, Rekha Thapar, Yasser S. Amer, Naohiro Yonemoto, Ahmad Ghashghaee, Amanda J. Mason-Jones, Marcela Agudelo-Botero, Ashraf Nabhan, Saeed Safari, Lorainne Tudor Car, Ayman Grada, Stanislav S. Otstavnov, Keyvan Pakshir, Nefsu Awoke, Ahamarshan Jayaraman Nagarajan, Adnan Kisa, Ghasem Azarian, Yogesh Sabde, Soufiane Boufous, Fatemeh Khosravi Shadmani, Ketema Bizuwork Gebremedhin, Heather Orpana, Narayan Bahadur Mahotra, Tripti Khanna, Peter Nyasulu, Tommi Vasankari, Reza Mohammadpourhodki, Peter Njenga Keiyoro, Andrea Werdecker, Sanghamitra Pati, Rajan Nikbakhsh, Sorin Hostiuc, Prateek Rastogi, Xuefeng Liu, Manasi Kumar, Josip Car, Chuanhua Yu, Aziz Rezapour, Narayana Manjunatha, Ritesh G. Menezes, Michael K. Hole, Asadollah Gholamian, Pascual R. Valdez, Lorenzo Monasta, Amit Arora, Marek Majdan, Abraham Getachew Kelbore, Irini Chatziralli, Rafael Alves Guimarães, Mohammad Hassan Emamian, Filippo Ariani, Jeadran N. Malagón-Rojas, Jae Il Shin, Aziz Sheikh, Garumma Tolu Feyissa, Ahmed Abdelalim, Babak Moazen, Smita Pakhale, Bija Soleymani, Mehdi Hosseinzadeh, Young Eun Kim, Yunquan Zhang, Guoqing Hu, Yousef Khader, Suzanne Barker-Collo, Rizwan Suliankatchi Abdulkader, Mahdi Safdarian, Arash Sarveazad, Maria Magdalena Constantin, Dhirendra N Sinha, Alireza Ansari-Moghaddam, Khezar Hayat, Ferrán Catalá-López, Shaun Wen Huey Lee, Susan M Sawyer, Soosanna Kumary Chattu, Salman Rawaf, Seyed Sina Naghibi Irvani, Eun-Kee Park, Nauman Khalid, Marwa Rashad Salem, Duduzile Ndwandwe, Carl Abelardo T. Antonio, Morteza Abdullatif Khafaie, Borhan Mansouri, Faramarz Shaahmadi, Rovshan Khalilov, Milena M Santric Milicevic, Pankaj Singh, Ashish Badiye, Ai Koyanagi, Priya Rathi, Sanni Yaya, Ali Bijani, Shanshan Li, Onome Bright Oghenetega, Manoochehr Karami, Huong Lan Thi Nguyen, Soheil Hassanipour, Chukwudi A Nnaji, Obinna Onwujekwe, Swayam Prakash, Animut Tagele Tamiru, Ted R. Miller, Rebecca Ivers, Paulo A. Lotufo, Tomislav Mestrovic, Bhaskaran Unnikrishnan, Morteza Shamsizadeh, Abdollah Mohammadian-Hafshejani, Savita Lasrado, Amir Almasi-Hashiani, Burcu Kucuk Bicer, Samad Azari, Degena Bahrey Tadesse, Ziad El-Khatib, Ashish Pathak, Kebreab Paulos, Krittika Bhattacharyya, Animut Alebel, Rupak Desai, Rafael Tabarés-Seisdedos, Melkamu Merid Mengesha, Ayenew Kassie Tesema, Amir Radfar, Shane D. Morrison, Inga Dora Sigfusdottir, Hamid Yimam Hassen, Miloud Taki Eddine Aichour, Getnet Gedefaw, Hamed Zandian, Chi Linh Hoang, Seyedmojtaba Seyedmousavi, Desalegn Getnet Demsie, Fares Alahdab, Vafa Rahimi-Movaghar, Atalay Goshu Muluneh, Leeberk Raja Inbaraj, Muluken Bekele Sorrie, Olayinka Stephen Ilesanmi, Om P Kurmi, Subramanian Senthilkumaran, Ahmed Omar Bali, Wagaye Fentahun Chanie, Abadi Kahsu Gebre, Neha Chaudhary, Endang Indriasih, Neeraj Bedi, Ghobad Moradi, Pankaj Bhardwaj, Erkin M. Mirrakhimov, Daniel Y. Cho, Karen M. Tabb, Elham Ehsani-Chimeh, Kamarul Imran Musa, Mustafa Z. Younis, Meresa Berwo Mengesha, Veincent Christian Filipino Pepito, Jalal Arabloo, Mukhammad David Naimzada, Ingan Ukur Tarigan, Eleni Bagli, Prasanna Mithra, Masood Ali Shaikh, Siamak Sabour, Theo Vos, Van C. Lansingh, Cuong Tat Nguyen, Dennis Odai Laryea, Tuomo J. Meretoja, Ireneous N. Soyiri, Mariam Molokhia, Biruk Wogayehu Taddele, Robert C. Reiner, Till Bärnighausen, Walter Mendoza, Maciej Banach, Justin J. Lang, Maysaa El Sayed Zaki, Martha Híjar, Farahnaz Joukar, João Mauricio Castaldelli-Maia, R V Polibin, Sudha Jayaraman, S. Mohammad Sajadi, Cyrus Alinia, Nicholas L S Roberts, Aso Mohammad Darwesh, Akine Eshete Abosetugn, Mostafa Dianati Nasab, Samar Al-Hajj, Jagadish Rao Padubidri, Gebretsadkan Hintsa Tekulu, Kidanemaryam Berhe, Mehdi Mirzaei-Alavijeh, Hasan Yusefzadeh, Felix Akpojene Ogbo, Mahesh P A, Amir Manafi, Berhe Gebremichael, Carlos Miguel Rios González, Rahman Shiri, Girmay Teklay Weldesamuel, Pallab K. Maulik, Suresh Jungari, Ali Yadollahpour, Ali H. Mokdad, Alan D. Lopez, Masoud Behzadifar, Naho Morisaki, Nithin Kumar, Corina Benjet, Seyed-Mohammad Fereshtehnejad, Nikita Otstavnov, Vahid Yazdi-Feyzabadi, Serge Resnikoff, Inbal Salz, Muhammed Magdy Abd El Razek, Taweewat Wiangkham, Vinod C. Nayak, Niguse Meles Alema, G Anil Kumar, Mohammed Ibrahim Mohialdeen Gubari, Yoshan Moodley, Amir Kasaeian, Nitin Joseph, Mihajlo Jakovljevic, Farnam Mohebi, Navid Rabiee, Ali Kabir, Hossein Poustchi, Gebrekiros Gebremichael Meles, Asres Bedaso Tilahune, Yonatal Mesfin Tefera, Abdur Razzaque Sarker, Zoubida Zaidi, Hung Chak Ho, Andre M. N. Renzaho, Vahid Alipour, Sowmya J. Rao, Francesco Saverio Violante, Monika Sawhney, Daniel N. Kiirithio, Josephine W. Ngunjiri, Muhammad Aziz Rahman, Amin Soheili, Félix Carvalho, Hafiz Ansar Rasul Suleria, Saleh Salehi Zahabi, Benjamin B. Massenburg, Yun Jin Kim, Tomas Y Ferede, Saqib Ali, Yousef Mohammad, Getinet Ayano, Zabihollah Yousefi, Neeti Kapoor, Lope H Barrero, Hosni Salem, Sharareh Eskandarieh, Hai Quang Pham, Zahra Sadat Dibaji Forooshani, Erika Ota, Srikanta Banerjee, Babak Asghari, Arash Tehrani-Banihashemi, Dina Nur Anggraini Ningrum, Tauseef Ahmad, Giovanni Damiani, Hamidreza Komaki, Catalina Liliana Andrei, Karzan Abdulmuhsin Mohammad, Rosario Cárdenas, Richard C. Franklin, Naznin Hossain, Miriam Levi, Hayimro Edemealem Merie, Kavitha Ranganathan, Anwar Rafay, Srinivas Murthy, Engida Yisma, Mehdi Sayyah, Bruno Ramos Nascimento, Lalit Dandona, Ahmad Zarei, Kwaku Oppong Asante, Masoud Moradi, Luca Ronfani, Berhe Etsay Tesfay, Prabhat Lamichhane, Juan Sanabria, Brijesh Sathian, Daniel Kim, Yoosik Youm, Kewal Krishan, Maryam Zamanian, Christian Lycke Ellingsen, Dawit Habte Woldeyes, Josep Maria Haro, Gebre Teklemariam Demoz, Zahiruddin Quazi Syed, Hamid Sharifi, Dinh-Toi Chu, Vasily Vlassov, Emmanuel Wandera Okunga, Sanjay Zodpey, Birhanu Geta, Amaha Kahsay, Mark A. Stokes, Faris Lami, Yousef Fatahi, Moritz U. G. Kraemer, Anusha Ganapati Bhat, Naser Mohammad Gholi Mezerji, Samantha M. Colquhoun, Louisa Degenhardt, Ivo Rakovac, Saeed Amini, Sadaf G. Sepanlou, Claudio Alberto Dávila-Cervantes, Asmamaw Demis, Samer Hamidi, Teshome Abegaz Kamil, Muhammad Shahdaat Bin Sayeed, In-Hwan Oh, Afshin Derakhshani, Sojib Bin Zaman, Peter Memiah, Andreea Mirica, Dawit Zewdu Wondafrash, Sheikh Mohammed Shariful Islam, Oluwatosin Kuti, Shivakumar K.M. Kondlahalli, Soraya Seedat, Mohammad Ali Jahani, Bereket Duko Adema, Paul S. F. Yip, Gurudatta Naik, Ali Rajabpour-Sanati, Farid Najafi, Kebede Deribe, Ionut Negoi, Malke Asaad, Mehedi Hasan, Tim Driscoll, Reza Rawassizadeh, Vishnu Renjith, Taras Kavetskyy, Masoud Foroutan, Akbar Barzegar, Mohsen Bayati, Mohammad Ali Mansournia, Zohreh Arefi, Saif Ullah, Fatemeh Heydarpour, Joemer C. Maravilla, Masoud Moghadaszadeh, Rasmus Havmoeller, Pietro Ferrara, Vijay Kumar Chattu, Rohollah Kalhor, Amrit Banstola, Payman Salamati, Genet Melak Alamene, George C Patton, André Faro, Rushdia Ahmed, Era Upadhyay, Vivek Kumar, Mahmood Moosazadeh, Temesgen Gebeyehu Wondmeneh, Vladimir Andreevich Korshunov, Soraya Siabani, Shyam Sundar Budhathoki, Alexander C. Tsai, Suliman Alghnam, Irena Ilic, Tsegaye Lolaso Lenjebo, Andrew T Olagunju, Mohan Bairwa, Amy E. Peden, Catalin-Gabriel Smarandache, Ejaz Ahmad Khan, Spencer L. James, Ronan A Lyons, Seok Jun Yoon, Siavash Rahimi, Kathryn H. Jacobsen, Morenike Oluwatoyin Folayan, Zachary V Dingels, Florian Fischer, Joht Singh Chandan, Amir Abdoli, Takeshi Fukumoto, Tariku Tesfaye Bekuma, Efat Mohamadi, David C. Schwebel, Milena Ilic, Daniel Adane Endalew, Mahdi Sharif-Alhoseini, Jost B. Jonas, Mahtab Alikhani, Fariborz Mansour-Ghanaei, Bach Xuan Tran, Lal B. Rawal, Lyn March, Ester Cerin, Martin Amogre Ayanore, Morteza Naserbakht, Hamid Safarpour, Sangram Kishor Patel, Vera Marisa Costa, Ai-Min Wu, Raimundas Lunevicius, Suzanne Polinder, Mika Shigematsu, Bryan L. Sykes, Zeleke Aschalew Melketsedik, Nuworza Kugbey, M. Mofizul Islam, Atif Amin Baig, Ana Isabel Ribeiro, Joel M. Francis, Alexandra Brazinova, Nader Jahanmehr, Yuming Guo, Sonia Saxena, Nima Hafezi-Nejad, Khanh Bao Tran, Mansour Ghafourifard, Navid Manafi, Chris D Castle, Brian J. Hall, Ravi Prakash Jha, Joan B. Soriano, Rajendra Kadel, Beatriz Paulina Ayala Quintanilla, Oladimeji Adebayo, Arianna Maever L. Amit, Kerrie E. Doyle, Olalekan A. Uthman, Farshad Farzadfar, Janet L Leasher, Shafiu Mohammed, Paolo Lauriola, Tilahun Belete Mossie, Nihad A. Almasri, Fakher Rahim, Dillon O Sylte, Emma Smith, Palash Chandra Banik, Muktar Beshir Ahmed, Achala Upendra Jayatilleke, Arman Latifi, Carlo La Vecchia, Randah R. Hamadeh, G. K. Mini, Kenean Getaneh Tlaye, Dan J. Stein, Leila R Kalankesh, Abdelrahman Ibrahim Abushouk, Mikk Jürisson, Habte Belete, Atte Meretoja, Yasir Waheed, Fahad Alanezi, Hadi Hassankhani, Shai Linn, Anas M. Saad, Yong Yu, Aidin Abedi, Mohammad Rabiee, Jaya Prasad Tripathy, Jack T Fox, Abdallah M. Samy, Roman Topor-Madry, Michal Grivna, Adam Belay Wondmieneh, Narayanaswamy Venketasubramanian, Addisu Melese, Mohammad Khammarnia, Fatemeh Rajati, Arun Balachandran, Juanita A. Haagsma, Segun Emmanuel Ibitoye, Telma Zahirian Moghadam, Maseer Khan, Sezer Kisa, Basema Saddik, Ahad Bakhtiari, Maziar Moradi-Lakeh, Dimas Ria Angga Pribadi, Habibolah Khazaie, Ghulam Mustafa, Ata Rafiee, Benn Sartorius, HUS Comprehensive Cancer Center, Clinicum, University of Helsinki, Helsinki University Hospital Area, HUS Neurocenter, Public Health, Instituto de Saúde Pública da Universidade do Porto, James SL, Violante FS, Vos T., Sálfræðideild (HR), Department of Psychology (RU), Samfélagssvið (HR), School of Social Sciences (RU), Háskólinn í Reykjavík, Reykjavik University, James, S, Castle, C, Dingels, Z, Fox, J, Hamilton, E, Liu, Z, S Roberts, N, Sylte, D, Henry, N, Legrand, K, Abdelalim, A, Abdoli, A, Abdollahpour, I, Abdulkader, R, Abedi, A, Abosetugn, A, Abushouk, A, Adebayo, O, Agudelo-Botero, M, Ahmad, T, Ahmed, R, Ahmed, M, Eddine Aichour, M, Alahdab, F, Alamene, G, Alanezi, F, Alebel, A, Alema, N, Alghnam, S, Al-Hajj, S, Ali, B, Ali, S, Alikhani, M, Alinia, C, Alipour, V, Aljunid, S, Almasi-Hashiani, A, Almasri, N, Altirkawi, K, Abdeldayem Amer, Y, Amini, S, Loreche Amit, A, Andrei, C, Ansari-Moghaddam, A, T Antonio, C, Yaw Appiah, S, Arabloo, J, Arab-Zozani, M, Arefi, Z, Aremu, O, Ariani, F, Arora, A, Asaad, M, Asghari, B, Awoke, N, Ayala Quintanilla, B, Ayano, G, Ayanore, M, Azari, S, Azarian, G, Badawi, A, Badiye, A, Bagli, E, Baig, A, Bairwa, M, Bakhtiari, A, Balachandran, A, Banach, M, Banerjee, S, Banik, P, Banstola, A, Barker-Collo, S, Barnighausen, T, Barrero, L, Barzegar, A, Bayati, M, Baye, B, Bedi, N, Behzadifar, M, Bekuma, T, Belete, H, Benjet, C, Bennett, D, Bensenor, I, Berhe, K, Bhardwaj, P, Bhat, A, Bhattacharyya, K, Bibi, S, Bijani, A, Bin Sayeed, M, Borges, G, Borzi, A, Boufous, S, Brazinova, A, Briko, N, Budhathoki, S, Car, J, Cardenas, R, Carvalho, F, Castaldelli-Maia, J, Castaneda-Orjuela, C, Castelpietra, G, Catala-Lopez, F, Cerin, E, Chandan, J, Chanie, W, Chattu, S, Chattu, V, Chatziralli, I, Chaudhary, N, Cho, D, Kabir Chowdhury, M, Chu, D, Colquhoun, S, Constantin, M, Costa, V, Damiani, G, Daryani, A, Davila-Cervantes, C, Demeke, F, Demis, A, Demoz, G, Demsie, D, Derakhshani, A, Deribe, K, Desai, R, Nasab, M, Da Silva, D, Dibaji Forooshani, Z, Doyle, K, Driscoll, T, Dubljanin, E, Adema, B, Eagan, A, Eftekhari, A, Ehsani-Chimeh, E, Sayed Zaki, M, Elemineh, D, El-Jaafary, S, El-Khatib, Z, Ellingsen, C, Emamian, M, Endalew, D, Eskandarieh, S, Faris, P, Faro, A, Farzadfar, F, Fatahi, Y, Fekadu, W, Ferede, T, Fereshtehnejad, S, Fernandes, E, Ferrara, P, Feyissa, G, Filip, I, Fischer, F, Folayan, M, Foroutan, M, Francis, J, Franklin, R, Fukumoto, T, Geberemariyam, B, Gebre, A, Gebremedhin, K, Gebremeskel, G, Gebremichael, B, Gedefaw, G, Geta, B, Ghafourifard, M, Ghamari, F, Ghashghaee, A, Gholamian, A, Gill, T, Goulart, A, Grada, A, Grivna, M, Mohialdeen Gubari, M, Guimaraes, R, Guo, Y, Gupta, G, Haagsma, J, Hafezi-Nejad, N, Bidgoli, H, Hall, B, Hamadeh, R, Hamidi, S, Haro, J, Hasan, M, Hasanzadeh, A, Hassanipour, S, Hassankhani, H, Hassen, H, Havmoeller, R, Hayat, K, Hendrie, D, Heydarpour, F, Hijar, M, Ho, H, Hoang, C, Hole, M, Holla, R, Hossain, N, Hosseinzadeh, M, Hostiuc, S, Hu, G, Ibitoye, S, Ilesanmi, O, Ilic, I, Ilic, M, Inbaraj, L, Indriasih, E, Naghibi Irvani, S, Shariful Islam, S, Islam, M, Ivers, R, Jacobsen, K, Jahani, M, Jahanmehr, N, Jakovljevic, M, Jalilian, F, Jayaraman, S, Jayatilleke, A, Jha, R, John-Akinola, Y, Jonas, J, Joseph, N, Joukar, F, Jozwiak, J, Jungari, S, Jurisson, M, Kabir, A, Kadel, R, Kahsay, A, Kalankesh, L, Kalhor, R, Kamil, T, Kanchan, T, Kapoor, N, Karami, M, Kasaeian, A, Kassaye, H, Kavetskyy, T, Kebede, H, Keiyoro, P, Kelbore, A, Kelkay, B, Khader, Y, Khafaie, M, Khalid, N, Khalil, I, Khalilov, R, Khammarnia, M, Khan, E, Khan, M, Khanna, T, Khazaie, H, Shadmani, F, Khundkar, R, Kiirithio, D, Kim, Y, Kim, D, Kisa, A, Kisa, S, Komaki, H, M Kondlahalli, S, Korshunov, V, Koyanagi, A, G Kraemer, M, Krishan, K, Bicer, B, Kugbey, N, Kumar, V, Kumar, N, Kumar, G, Kumar, M, Kumaresh, G, Kurmi, O, Kuti, O, Vecchia, C, Lami, F, Lamichhane, P, Lang, J, Lansingh, V, Laryea, D, Lasrado, S, Latifi, A, Lauriola, P, Leasher, J, Huey Lee, S, Lenjebo, T, Levi, M, Li, S, Linn, S, Liu, X, Lopez, A, Lotufo, P, Lunevicius, R, Lyons, R, Madadin, M, El Razek, M, Mahotra, N, Majdan, M, Majeed, A, Malagon-Rojas, J, Maled, V, Malekzadeh, R, Malta, D, Manafi, N, Manafi, A, Manda, A, Manjunatha, N, Mansour-Ghanaei, F, Mansouri, B, Mansournia, M, Maravilla, J, March, L, Mason-Jones, A, Masoumi, S, Massenburg, B, Maulik, P, Meles, G, Melese, A, Melketsedik, Z, N Memiah, P, Mendoza, W, Menezes, R, Mengesha, M, Meretoja, T, Meretoja, A, Merie, H, Mestrovic, T, Miazgowski, B, Miazgowski, T, Miller, T, Mini, G, Mirica, A, Mirrakhimov, E, Mirzaei-Alavijeh, M, Mithra, P, Moazen, B, Moghadaszadeh, M, Mohamadi, E, Mohammad, Y, Mohammad, K, Darwesh, A, Gholi Mezerji, N, Mohammadian-Hafshejani, A, Mohammadoo-Khorasani, M, Mohammadpourhodki, R, Mohammed, S, Mohammed, J, Mohebi, F, Molokhia, M, Monasta, L, Moodley, Y, Moosazadeh, M, Moradi, M, Moradi, G, Moradi-Lakeh, M, Moradpour, F, Morawska, L, Velasquez, I, Morisaki, N, Morrison, S, Mossie, T, Muluneh, A, Murthy, S, Musa, K, Mustafa, G, Nabhan, A, Nagarajan, A, Naik, G, Naimzada, M, Najafi, F, Nangia, V, Nascimento, B, Naserbakht, M, Nayak, V, Ndwandwe, D, Negoi, I, Ngunjiri, J, Nguyen, C, Thi Nguyen, H, Nikbakhsh, R, Anggraini Ningrum, D, Nnaji, C, Nyasulu, P, Ogbo, F, Oghenetega, O, Oh, I, Okunga, E, Olagunju, A, Olagunju, T, Bali, A, Onwujekwe, O, Asante, K, Orpana, H, Ota, E, Otstavnov, N, Otstavnov, S, Mahesh, P, Padubidri, J, Pakhale, S, Pakshir, K, Panda-Jonas, S, Park, E, Patel, S, Pathak, A, Pati, S, Patton, G, Paulos, K, Peden, A, Filipino Pepito, V, Pereira, J, Pham, H, Phillips, M, Pinheiro, M, Polibin, R, Polinder, S, Poustchi, H, Prakash, S, Angga Pribadi, D, Puri, P, Syed, Z, Rabiee, M, Rabiee, N, Radfar, A, Rafay, A, Rafiee, A, Rafiei, A, Rahim, F, Rahimi, S, Rahimi-Movaghar, V, Rahman, M, Rajabpour-Sanati, A, Rajati, F, Rakovac, I, Ranganathan, K, Rao, S, Rashedi, V, Rastogi, P, Rathi, P, Rawaf, S, Rawal, L, Rawassizadeh, R, Renjith, V, N Renzaho, A, Resnikoff, S, Rezapour, A, Ribeiro, A, Rickard, J, Rios Gonzalez, C, Ronfani, L, Roshandel, G, Saad, A, Sabde, Y, Sabour, S, Saddik, B, Safari, S, Safari-Faramani, R, Safarpour, H, Safdarian, M, Sajadi, S, Salamati, P, Salehi, F, Zahabi, S, Rashad Salem, M, Salem, H, Salman, O, Salz, I, Samy, A, Sanabria, J, Riera, L, Santric Milicevic, M, Sarker, A, Sarveazad, A, Sathian, B, Sawhney, M, Sawyer, S, Saxena, S, Sayyah, M, Schwebel, D, Seedat, S, Senthilkumaran, S, Sepanlou, S, Seyedmousavi, S, Sha, F, Shaahmadi, F, Shahabi, S, Shaikh, M, Shams-Beyranvand, M, Shamsizadeh, M, Sharif-Alhoseini, M, Sharifi, H, Sheikh, A, Shigematsu, M, Shin, J, Shiri, R, Siabani, S, Sigfusdottir, I, Singh, P, Singh, J, Sinha, D, Smarandache, C, R Smith, E, Soheili, A, Soleymani, B, Soltanian, A, Soriano, J, Sorrie, M, Soyiri, I, Stein, D, Stokes, M, Sufiyan, M, Rasul Suleria, H, Sykes, B, Tabares-Seisdedos, R, Tabb, K, Taddele, B, Tadesse, D, Tamiru, A, Tarigan, I, Tefera, Y, Tehrani-Banihashemi, A, Tekle, M, Tekulu, G, Tesema, A, Tesfay, B, Thapar, R, Tilahune, A, Tlaye, K, Tohidinik, H, Topor-Madry, R, Tran, B, Tran, K, Tripathy, J, Tsai, A, Car, L, Ullah, S, Ullah, I, Umar, M, Unnikrishnan, B, Upadhyay, E, Uthman, O, Valdez, P, Vasankari, T, Venketasubramanian, N, Violante, F, Vlassov, V, Waheed, Y, Weldesamuel, G, Werdecker, A, Wiangkham, T, Wolde, H, Woldeyes, D, Wondafrash, D, Wondmeneh, T, Wondmieneh, A, Wu, A, Yadav, R, Yadollahpour, A, Yano, Y, Yaya, S, Yazdi-Feyzabadi, V, Yip, P, Yisma, E, Yonemoto, N, Yoon, S, Youm, Y, Younis, M, Yousefi, Z, Yu, Y, Yu, C, Yusefzadeh, H, Moghadam, T, Zaidi, Z, Zaman, S, Zamani, M, Zamanian, M, Zandian, H, Zarei, A, Zare, F, Zhang, Z, Zhang, Y, Zodpey, S, Dandona, L, Dandona, R, Degenhardt, L, Dharmaratne, S, Hay, S, Mokdad, A, Reiner Jr, R, Sartorius, B, Vos, T, James, S. L., Castle, C. D., Dingels, Z. V., Fox, J. T., Hamilton, E. B., Liu, Z., Roberts, N. L. S., Sylte, D. O., Henry, N. J., Legrand, K. E., Abdelalim, A., Abdoli, A., Abdollahpour, I., Abdulkader, R. S., Abedi, A., Abosetugn, A. E., Abushouk, A. I., Adebayo, O. M., Agudelo-Botero, M., Ahmad, T., Ahmed, R., Ahmed, M. B., Aichour, M. T. E., Alahdab, F., Alamene, G. M., Alanezi, F. M., Alebel, A., Alema, N. M., Alghnam, S. A., Al-Hajj, S., Ali, B. A., Ali, S., Alikhani, M., Alinia, C., Alipour, V., Aljunid, S. M., Almasi-Hashiani, A., Almasri, N. A., Altirkawi, K., Amer, Y. S. A., Amini, S., Amit, A. M. L., Andrei, C. L., Ansari-Moghaddam, A., Antonio, C. A. T., Appiah, S. C. Y., Arabloo, J., Arab-Zozani, M., Arefi, Z., Aremu, O., Ariani, F., Arora, A., Asaad, M., Asghari, B., Awoke, N., Quintanilla, B. P. A., Ayano, G., Ayanore, M. A., Azari, S., Azarian, G., Badawi, A., Badiye, A. D., Bagli, E., Baig, A. A., Bairwa, M., Bakhtiari, A., Balachandran, A., Banach, M., Banerjee, S. K., Banik, P. C., Banstola, A., Barker-Collo, S. L., Barnighausen, T. W., Barrero, L. H., Barzegar, A., Bayati, M., Baye, B. A., Bedi, N., Behzadifar, M., Bekuma, T. T., Belete, H., Benjet, C., Bennett, D. A., Bensenor, I. M., Berhe, K., Bhardwaj, P., Bhat, A. G., Bhattacharyya, K., Bibi, S., Bijani, A., Sayeed, M. S. B., Borges, G., Borzi, A. M., Boufous, S., Brazinova, A., Briko, N. I., Budhathoki, S. S., Car, J., Cardenas, R., Carvalho, F., Castaldelli-Maia, J. M., Castaneda-Orjuela, C. A., Castelpietra, G., Catala-Lopez, F., Cerin, E., Chandan, J. S., Chanie, W. F., Chattu, S. K., Chattu, V. K., Chatziralli, I., Chaudhary, N., Cho, D. Y., Chowdhury, M. A. K., Chu, D. -T., Colquhoun, S. M., Constantin, M. -M., Costa, V. M., Damiani, G., Daryani, A., Davila-Cervantes, C. A., Demeke, F. M., Demis, A. B., Demoz, G. T., Demsie, D. G., Derakhshani, A., Deribe, K., Desai, R., Nasab, M. D., Dias da Silva, D., Forooshani, Z. S. D., Doyle, K. E., Driscoll, T. R., Dubljanin, E., Adema, B. D., Eagan, A. W., Eftekhari, A., Ehsani-Chimeh, E., El Sayed Zaki, M., Elemineh, D. A., El-Jaafary, S. I., El-Khatib, Z., Ellingsen, C. L., Emamian, M. H., Endalew, D. A., Eskandarieh, S., Faris, P. S., Faro, A., Farzadfar, F., Fatahi, Y., Fekadu, W., Ferede, T. Y., Fereshtehnejad, S. -M., Fernandes, E., Ferrara, P., Feyissa, G. T., Filip, I., Fischer, F., Folayan, M. O., Foroutan, M., Francis, J. M., Franklin, R. C., Fukumoto, T., Geberemariyam, B. S., Gebre, A. K., Gebremedhin, K. B., Gebremeskel, G. G., Gebremichael, B., Gedefaw, G. A., Geta, B., Ghafourifard, M., Ghamari, F., Ghashghaee, A., Gholamian, A., Gill, T. K., Goulart, A. C., Grada, A., Grivna, M., Gubari, M. I. M., Guimaraes, R. A., Guo, Y., Gupta, G., Haagsma, J. A., Hafezi-Nejad, N., Bidgoli, H. H., Hall, B. J., Hamadeh, R. R., Hamidi, S., Haro, J. M., Hasan, M. M., Hasanzadeh, A., Hassanipour, S., Hassankhani, H., Hassen, H. Y., Havmoeller, R., Hayat, K., Hendrie, D., Heydarpour, F., Hijar, M., Ho, H. C., Hoang, C. L., Hole, M. K., Holla, R., Hossain, N., Hosseinzadeh, M., Hostiuc, S., Hu, G., Ibitoye, S. E., Ilesanmi, O. S., Ilic, I., Ilic, M. D., Inbaraj, L. R., Indriasih, E., Irvani, S. S. N., Islam, S. M. S., Mofizul Islam, M., Ivers, R. Q., Jacobsen, K. H., Jahani, M. A., Jahanmehr, N., Jakovljevic, M., Jalilian, F., Jayaraman, S., Jayatilleke, A. U., Jha, R. P., John-Akinola, Y. O., Jonas, J. B., Joseph, N., Joukar, F., Jozwiak, J. J., Jungari, S. B., Jurisson, M., Kabir, A., Kadel, R., Kahsay, A., Kalankesh, L. R., Kalhor, R., Kamil, T. A., Kanchan, T., Kapoor, N., Karami, M., Kasaeian, A., Kassaye, H. G., Kavetskyy, T., Kebede, H. K., Keiyoro, P. N., Kelbore, A. G., Kelkay, B., Khader, Y. S., Khafaie, M. A., Khalid, N., Khalil, I. A., Khalilov, R., Khammarnia, M., Khan, E. A., Khan, M., Khanna, T., Khazaie, H., Shadmani, F. K., Khundkar, R., Kiirithio, D. N., Kim, Y. -E., Kim, D., Kim, Y. J., Kisa, A., Kisa, S., Komaki, H., Kondlahalli, S. K. M., Korshunov, V. A., Koyanagi, A., Kraemer, M. U. G., Krishan, K., Bicer, B. K., Kugbey, N., Kumar, V., Kumar, N., Anil Kumar, G., Kumar, M., Kumaresh, G., Kurmi, O. P., Kuti, O., Vecchia, C. L., Lami, F. H., Lamichhane, P., Lang, J. J., Lansingh, V. C., Laryea, D. O., Lasrado, S., Latifi, A., Lauriola, P., Leasher, J. L., Lee, S. W. H., Lenjebo, T. L., Levi, M., Li, S., Linn, S., Liu, X., Lopez, A. D., Lotufo, P. A., Lunevicius, R., Lyons, R. A., Madadin, M., El Razek, M. M. A., Mahotra, N. B., Majdan, M., Majeed, A., Malagon-Rojas, J. N., Maled, V., Malekzadeh, R., Malta, D. C., Manafi, N., Manafi, A., Manda, A. -L., Manjunatha, N., Mansour-Ghanaei, F., Mansouri, B., Mansournia, M. A., Maravilla, J. C., March, L. M., Mason-Jones, A. J., Masoumi, S. Z., Massenburg, B. B., Maulik, P. K., Meles, G. G., Melese, A., Melketsedik, Z. A., Memiah, P. T. N., Mendoza, W., Menezes, R. G., Mengesha, M. B., Mengesha, M. M., Meretoja, T. J., Meretoja, A., Merie, H. E., Mestrovic, T., Miazgowski, B., Miazgowski, T., Miller, T. R., Mini, G. K., Mirica, A., Mirrakhimov, E. M., Mirzaei-Alavijeh, M., Mithra, P., Moazen, B., Moghadaszadeh, M., Mohamadi, E., Mohammad, Y., Mohammad, K. A., Darwesh, A. M., Mezerji, N. M. G., Mohammadian-Hafshejani, A., Mohammadoo-Khorasani, M., Mohammadpourhodki, R., Mohammed, S., Mohammed, J. A., Mohebi, F., Molokhia, M., Monasta, L., Moodley, Y., Moosazadeh, M., Moradi, M., Moradi, G., Moradi-Lakeh, M., Moradpour, F., Morawska, L., Velasquez, I. M., Morisaki, N., Morrison, S. D., Mossie, T. B., Muluneh, A. G., Murthy, S., Musa, K. I., Mustafa, G., Nabhan, A. F., Nagarajan, A. J., Naik, G., Naimzada, M. D., Najafi, F., Nangia, V., Nascimento, B. R., Naserbakht, M., Nayak, V., Ndwandwe, D. E., Negoi, I., Ngunjiri, J. W., Nguyen, C. T., Nguyen, H. L. T., Nikbakhsh, R., Ningrum, D. N. A., Nnaji, C. A., Nyasulu, P. S., Ogbo, F. A., Oghenetega, O. B., Oh, I. -H., Okunga, E. W., Olagunju, A. T., Olagunju, T. O., Bali, A. O., Onwujekwe, O. E., Asante, K. O., Orpana, H. M., Ota, E., Otstavnov, N., Otstavnov, S. S., Mahesh, P. A., Padubidri, J. R., Pakhale, S., Pakshir, K., Panda-Jonas, S., Park, E. -K., Patel, S. K., Pathak, A., Pati, S., Patton, G. C., Paulos, K., Peden, A. E., Pepito, V. C. F., Pereira, J., Pham, H. Q., Phillips, M. R., Pinheiro, M., Polibin, R. V., Polinder, S., Poustchi, H., Prakash, S., Pribadi, D. R. A., Puri, P., Syed, Z. Q., Rabiee, M., Rabiee, N., Radfar, A., Rafay, A., Rafiee, A., Rafiei, A., Rahim, F., Rahimi, S., Rahimi-Movaghar, V., Rahman, M. A., Rajabpour-Sanati, A., Rajati, F., Rakovac, I., Ranganathan, K., Rao, S. J., Rashedi, V., Rastogi, P., Rathi, P., Rawaf, S., Rawal, L., Rawassizadeh, R., Renjith, V., Renzaho, A. M. N., Resnikoff, S., Rezapour, A., Ribeiro, A. I., Rickard, J., Gonzalez, C. M. R., Ronfani, L., Roshandel, G., Saad, A. M., Sabde, Y. D., Sabour, S., Saddik, B., Safari, S., Safari-Faramani, R., Safarpour, H., Safdarian, M., Mohammad Sajadi, S., Salamati, P., Salehi, F., Zahabi, S. S., Rashad Salem, M. R., Salem, H., Salman, O., Salz, I., Samy, A. M., Sanabria, J., Riera, L. S., Santric Milicevic, M. M., Sarker, A. R., Sarveazad, A., Sathian, B., Sawhney, M., Sawyer, S. M., Saxena, S., Sayyah, M., Schwebel, D. C., Seedat, S., Senthilkumaran, S., Sepanlou, S. G., Seyedmousavi, S., Sha, F., Shaahmadi, F., Shahabi, S., Shaikh, M. A., Shams-Beyranvand, M., Shamsizadeh, M., Sharif-Alhoseini, M., Sharifi, H., Sheikh, A., Shigematsu, M., Shin, J. I., Shiri, R., Siabani, S., Sigfusdottir, I. D., Singh, P. K., Singh, J. A., Sinha, D. N., Smarandache, C. -G., Smith, E. U. R., Soheili, A., Soleymani, B., Soltanian, A. R., Soriano, J. B., Sorrie, M. B., Soyiri, I. N., Stein, D. J., Stokes, M. A., Mu'Awiyyah, B. S., Suleria, H. A. R., Sykes, B. L., Tabares-Seisdedos, R., Tabb, K. M., Taddele, B. W., Tadesse, D. B., Tamiru, A. T., Tarigan, I. U., Tefera, Y. M., Tehrani-Banihashemi, A., Tekle, M. G., Tekulu, G. H., Tesema, A. K., Tesfay, B. E., Thapar, R., Tilahune, A. B., Tlaye, K. G., Tohidinik, H. R., Topor-Madry, R., Tran, B. X., Tran, K. B., Tripathy, J. P., Tsai, A. C., Car, L. T., Ullah, S., Ullah, I., Umar, M., Unnikrishnan, B., Upadhyay, E., Uthman, O. A., Valdez, P. R., Vasankari, T. J., Venketasubramanian, N., Violante, F. S., Vlassov, V., Waheed, Y., Weldesamuel, G. T., Werdecker, A., Wiangkham, T., Wolde, H. F., Woldeyes, D. H., Wondafrash, D. Z., Wondmeneh, T. G., Wondmieneh, A. B., Wu, A. -M., Yadav, R., Yadollahpour, A., Yano, Y., Yaya, S., Yazdi-Feyzabadi, V., Yip, P., Yisma, E., Yonemoto, N., Yoon, S. -J., Youm, Y., Younis, M. Z., Yousefi, Z., Yu, Y., Yu, C., Yusefzadeh, H., Moghadam, T. Z., Zaidi, Z., Zaman, S. B., Zamani, M., Zamanian, M., Zandian, H., Zarei, A., Zare, F., Zhang, Z. -J., Zhang, Y., Zodpey, S., Dandona, L., Dandona, R., Degenhardt, L., Dharmaratne, S. D., Hay, S. I., Mokdad, A. H., Reiner, R. C., Sartorius, B., Vos, T., James, Spencer L, Castle, Chris D, Dingels, Zachary V, Fox, Jack T, Adema, Bereket Duko, Yisma, Engida, and Vos, Theo

Subjects
Dánarmein, Fötlun, Dánartíðni, Lífslíkur, Life expectancy, 1106 Human Movement and Sports Sciences, burden of disease, Global Health, Global Burden of Disease, 0302 clinical medicine, Quality-Adjusted Life Year, Global health, Medicine, LIFE EXPECTANCY, 030212 general & internal medicine, POPULATION, Cause of death, Original Research, RISK, education.field_of_study, Global disease burdens, Injuries, Sjúkdómar, Incidence (epidemiology), Incidence, Population health, Burden of disease, Global, global, 3142 Public health care science, environmental and occupational health, 3. Good health, Descriptive epidemiology, Lýðheilsa, Quality-Adjusted Life Years, Public Health, TERRITORIES, descriptive epidemiology, Human, Population, 195 COUNTRIES, Humans, Life Expectancy, Morbidity, Wounds and Injuries, 1117 Public Health and Health Services, 03 medical and health sciences, AGE, SYSTEMATIC ANALYSIS, Mortality, education, Disability, SEX-SPECIFIC MORTALITY, business.industry, Faraldsfræði, DISABILITY, Public Health, Environmental and Occupational Health, Quality-adjusted life year, Years of potential life lost, Áverkar, 1701 Psychology, Human medicine, business, 030217 neurology & neurosurgery, Demography
Abstract

Publisher's version (útgefin grein), Background Past research in population health trends has shown that injuries form a substantial burden of population health loss. Regular updates to injury burden assessments are critical. We report Global Burden of Disease (GBD) 2017 Study estimates on morbidity and mortality for all injuries. Methods We reviewed results for injuries from the GBD 2017 study. GBD 2017 measured injury-specific mortality and years of life lost (YLLs) using the Cause of Death Ensemble model. To measure non-fatal injuries, GBD 2017 modelled injury-specific incidence and converted this to prevalence and years lived with disability (YLDs). YLLs and YLDs were summed to calculate disability-adjusted life years (DALYs). Findings In 1990, there were 4 260 493 (4 085 700 to 4 396 138) injury deaths, which increased to 4 484 722 (4 332 010 to 4 585 554) deaths in 2017, while age-standardised mortality decreased from 1079 (1073 to 1086) to 738 (730 to 745) per 100 000. In 1990, there were 354 064 302 (95% uncertainty interval: 338 174 876 to 371 610 802) new cases of injury globally, which increased to 520 710 288 (493 430 247 to 547 988 635) new cases in 2017. During this time, age-standardised incidence decreased non-significantly from 6824 (6534 to 7147) to 6763 (6412 to 7118) per 100 000. Between 1990 and 2017, age-standardised DALYs decreased from 4947 (4655 to 5233) per 100 000 to 3267 (3058 to 3505). Interpretation Injuries are an important cause of health loss globally, though mortality has declined between 1990 and 2017. Future research in injury burden should focus on prevention in high-burden populations, improving data collection and ensuring access to medical care., Bill and Melinda Gates Foundation OPP1152504, "Peer Reviewed"

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results