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Glenoid component loosening remains the most common reason for revision of anatomic total shoulder arthroplasty (aTSA). We assessed early clinical and radiographic outcomes following aTSA using a press-fit short stem and a peripherally enhanced fixation glenoid. 275 consecutive patients with end-stage glenohumeral arthritis and Walch A- or B-type glenoid morphology who underwent primary aTSA in 2017-2018 at two high-volume shoulder arthroplasty institutions were evaluated, and patient-reported outcomes (PROMs) and radiographic findings were studied in those with completed baseline and minimum 2-year follow-up, respectively. Patient demographics, glenoid morphology, body mass index (BMI), Charlson Comorbidity Index (CCI), range of motion, American Shoulder and Elbow Surgeons (ASES) score, and Simple Assessment Numeric Evaluation score were collected. Radiographic analysis of glenoid and humeral components was performed. Multivariable logistic, equal adjacent odds ordinal, and beta regression were respectively used to identify predictors of glenoid radiolucent lines, humeral calcar resorption, and total ASES score. Patients were 43% female, with a mean age of 66, a median BMI of 30, and median follow-up of 28.4 months. ASES and Simple Assessment Numeric Evaluation scores improved by respective medians of 54.4 and 55.0 points, forward elevation by median 35°, and external rotation by median 30° (all P <.001 for preoperative to postoperative change). Postoperative radiographs of 177 cases showed 10 (5.7%) glenoid osteolysis, 51 (28.8%) glenoid radiolucent lines, and 81 (45.8%) calcar resorptions. The follow-up duration (median 40.1 vs. 27.2 months; P <.001), BMI (median 27.5 vs. 30.7; P <.001), and Charlson Comorbidity Index (Q3 0 vs. 1; P =.02) were associated with glenoid osteolysis in bivariate analyses. In multiple logistic regression, surgeon (C vs. A/B) was the only statistically significant predictor of glenoid radiolucent lines [OR 0.27, 95% CI (0.1, 0.8)]. By descending importance, Surgeon C [OR 6.5 (2.0, 20.5)], humeral canal filling ratio [upper vs. lower quartile OR 2.3 (1.3, 4.0)], mediolateral humeral head deviation [upper vs. lower quartile OR 1.9 (1.0, 3.5)], and glenoid osteolysis [OR 13.5 (2.6, 71.6)] significantly predicted greater calcar resorption. Longer follow-up duration marginally statistically significantly predicted lower ASES score [upper vs. lower quartile OR 0.8 (0.6, 1.0)]. Following aTSA with a peripherally enhanced fixation glenoid, pain, range of motion, and patient-reported outcomes significantly improved at a minimum of 2 years with only 5.7% glenoid osteolysis despite heterogeneous preoperative glenoid pathologies. [ABSTRACT FROM AUTHOR]

The purpose of the study was to describe the characteristics and demonstrate proof-of-concept and clinical use of a barium sulfate infused polypropylene radiopaque tissue marker for soft tissue localization and in vivo measurement of lengths and areas. Marker mechanical properties were evaluated by tensile tests. Biocompatibility was evaluated following 8–12 weeks' implantation in a pig model. Proof-of-concept of marker application was performed in a human cadaveric shoulder model, and methods for CT imaging and measurement of dimensions were established. Lastly, the method of clinical use of the markers was described in one patient undergoing arthroscopic rotator cuff repair (RCR). The radiopaque markers had a tensile strength of 28 ±4.7 N and were associated with minimal to mild inflammatory tissue reaction similar to polypropylene control. CT-based measurements showed relatively high precisions for lengths (0.66 mm), areas (6.97 mm2), and humeral orientation angles (2.1°) in the cadaveric model, and demonstrated 19 ±3 mm medio-lateral tendon retraction and 227 ±3 mm2 increase in tendon area in the patient during 26 weeks following RCR. No radiographic leaching, calcification or local adverse events were observed. The radiopaque tissue marker was biocompatible and had adequate strength for handling and affixation to soft tissues using standard suturing techniques. The marker could be used with low-dose, sequential CT imaging to quantitatively measure rotator cuff tendon retractions with clinically acceptable accuracy. We envision the radiopaque tissue marker to be useful for soft tissue localization and in vivo measurement of tissue and organ dimensions following surgery. [ABSTRACT FROM AUTHOR]

Background: Use of 3-dimensional (3D) computed tomography (CT) preoperative planning and patient-specific instrumentation has been demonstrated to improve the accuracy of glenoid implant placement in total shoulder arthroplasty (TSA). The purpose of this study was to compare the accuracy of glenoid implant placement in primary TSA among different types of instrumentation used with the 3D CT preoperative planning.Methods: One hundred and seventy-three patients with end-stage glenohumeral arthritis were enrolled in 3 prospective studies evaluating patient-specific instrumentation and 3D preoperative planning. All patients underwent preoperative 3D CT planning to determine optimal glenoid component and guide pin position based on surgeon preference. Patients were placed into 1 of 5 instrument groups used for intraoperative guide pin placement: (1) standard instrumentation, (2) standard instrumentation combined with use of a 3D glenoid bone model containing the guide pin, (3) use of the 3D glenoid bone model combined with single-use patient-specific instrumentation, (4) use of the 3D glenoid bone model combined with reusable patient-specific instrumentation, and (5) use of reusable patient-specific instrumentation with an adjustable, reusable base. Postoperatively, all patients underwent 3D CT to compare actual versus planned glenoid component position. Deviation from the plan (in terms of orientation and location) was compared across groups on the basis of absolute differences and outlier analysis. Univariable and multivariable comparisons were performed. As the initial analyses showed no significant differences in preoperative factors or in deviation from the plan between Groups 1 and 2 or between Groups 4 and 5 across studies, the final analysis was across 3 major treatment groups: standard instrumentation (Groups 1 and 2), single-use patient-specific instrumentation (Group 3), and reusable patient-specific instrumentation (Groups 4 and 5).Results: In nearly all comparisons, there were no significant differences in the deviation from the plan (absolute differences or outlier frequency) for glenoid implant orientation or location across the 3 major treatment groups.Conclusions: This study did not demonstrate that any type of patient-specific instrumentation resulted in consistent differences in accuracy of glenoid implant placement in primary TSA with 3D CT preoperative planning. Surgeons have multiple patient-specific instrumentation options available for improving accuracy of glenoid implant placement when compared with 2D imaging without patient-specific instrumentation.Level Of Evidence: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence. [ABSTRACT FROM AUTHOR]

Background: Scapular notching is frequently observed following reverse total shoulder arthroplasty (rTSA), although the etiology is not well understood.Methods: Twenty-nine patients with preoperative computed tomography (CT) scans who underwent rTSA with a Grammont design were evaluated after a minimum of 2 years of follow-up with video motion analysis (VMA), postoperative three-dimensional (3D) CT, and standard radiographs. The glenohumeral range of motion demonstrated by the VMA and the postoperative implant location on the CT were used in custom simulation software to determine areas of osseous impingement between the humeral implant and the scapula and their relationship to scapular notching on postoperative CT. Patients with and without notching were compared with one another by univariable and multivariable analyses to determine factors associated with notching.Results: Seventeen patients (59%) had scapular notching, which was along the posteroinferior aspect of the scapular neck in all of them and along the anteroinferior aspect of the neck in 3 of them. Osseous impingement occurred in external rotation with the arm at the side in 16 of the 17 patients, in internal rotation with the arm at the side in 3, and in adduction in 12. The remaining 12 patients did not have notching or osseous impingement. Placing the glenosphere in a position that was more inferior (by a mean of 3.4 ± 2.3 mm) or lateral (by a mean of 6.2 ± 1.4 mm) would have avoided most impingement in the patients' given range of motion. Notching was associated with glenosphere placement that was insufficiently inferior (mean inferior translation, -0.3 ± 3.4 mm in the notching group versus 3.0 ± 2.9 mm in the no-notching group; p = 0.01) or posterior (mean, -0.3 ± 3.5 mm versus 4.2 ± 2.2 mm; p < 0.001). Two-variable models showed inferior and posterior (area under the curve [AUC], 0.887; p < 0.001), inferior and lateral (AUC, 0.892; p < 0.001), and posterior and lateral (AUC, 0.892; p < 0.001) glenosphere positions to be significant predictors of the ability to avoid scapular notching.Conclusions: Osseous impingement identified using patients' actual postoperative range of motion and implant position matched the location of scapular notching seen radiographically. Inferior, lateral, and posterior glenosphere positions are all important factors in the ability to avoid notching. Only small changes in implant position were needed to avoid impingement, suggesting that preoperative determination of the ideal implant position may be a helpful surgical planning tool to avoid notching when using this implant design.Level Of Evidence: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. [ABSTRACT FROM AUTHOR]

Background: Glenoid morphology and rotator cuff muscle quality are important anatomic factors that can impact longevity of the glenoid component following total shoulder arthroplasty (TSA). We hypothesized that rotator cuff muscle fatty infiltration is associated with increased pathologic glenoid bone loss in glenohumeral osteoarthritis (OA).Methods: We retrospectively reviewed 190 preoperative computed tomography (CT) scans of 175 patients (mean age, 66 years; range, 44 to 90 years) who underwent TSA for the treatment of primary glenohumeral OA. Two-dimensional orthogonal CT images were reformatted in the plane of the scapula from 3-dimensional images. Pathologic joint-line medialization was defined with use of the glenoid vault model. Pathologic glenoid version was measured directly. Glenoid morphology was graded according to a modified Walch classification (subtypes A1, A2, B1, B2, B3, C1, and C2). Rotator cuff muscle fatty infiltration was assessed and assigned a Goutallier score on the sagittal CT slice just medial to the spinoglenoid notch for each muscle.Results: There was a significant difference in the Goutallier score for the supraspinatus, infraspinatus, and teres minor muscles between Walch subtypes (p ≤ 0.05). High-grade posterior rotator cuff muscle fatty infiltration was present in 55% (21) of 38 B3 glenoids compared with 8% (3) of 39 A1 glenoids. Increasing joint-line medialization was associated with increasing fatty infiltration of all rotator cuff muscles (p ≤ 0.05). Higher fatty infiltration of the infraspinatus, teres minor, and combined posterior rotator cuff muscles was associated with increasing glenoid retroversion (p ≤ 0.05). After controlling for joint-line medialization and retroversion, B3 glenoids were more likely to have fatty infiltration of the supraspinatus and infraspinatus muscles than B2 glenoids were.Conclusions: High-grade rotator cuff muscle fatty infiltration is associated with B3 glenoids, increased pathologic glenoid retroversion, and increased joint-line medialization. Additional studies are needed to determine the causal relationship between these muscle changes and glenoid wear, whether these muscle changes independently affect clinical and radiographic outcomes in anatomic TSA, and whether fatty infiltration can improve postoperatively with correction of pathologic version and/or joint-line restoration.Clinical Relevance: This study investigates the association between different patterns of glenoid bone loss and rotator cuff muscle fatty infiltration. Both factors have been shown to affect clinical outcome following TSA. [ABSTRACT FROM AUTHOR]

Background: Walch defined the pathologic characteristics of glenohumeral osteoarthritis on the basis of patterns of glenoid morphology and humeral head subluxation. However, it is unclear how pathologic changes evolve over time. The purpose of this study was to determine whether there are common patterns of pathologic progression based on the Walch classification in primary glenohumeral osteoarthritis and if glenoid bone-loss patterns correlate with rotator cuff fatty infiltration.Methods: A retrospective chart review identified 65 shoulders with glenohumeral osteoarthritis for which at least 2 computed tomography (CT) scans had been performed at least 24 months apart. The CT scans were classified using a modification of the Walch classification. The amount and location of glenoid bone loss were measured using a vault model, and rotator cuff fatty infiltration was calculated as a percentage of cross-sectional muscle area.Results: The initial CT scans showed 42 A-type glenoids and 23 B-type glenoids. CT scans made at an average (and standard deviation) of 74 ± 32 months after the initial scans showed that only 8 of the 42 A1 glenoids had evidence of pathologic progression (5 to A2 type and 3 to B type) whereas 17 of 19 B1 glenoids had progressed (15 to B2 and 2 to B3); this difference was significant on univariate and multivariate analysis (p < 0.001). The odds of joint line medialization occurring were 8.1 times higher (95% confidence interval [CI]: 2.1 to 31.4) for B-type glenoids than for A-type glenoids. Among the glenoids that underwent medialization, those classified as B-type showed more medialization over time (estimated change, 0.70 mm/year; p = 0.036), whereas no significant relationship between medialization and time was observed for A-type glenoids (estimated change, 0.013 mm/year; p = 0.95). The median percent fatty infiltration in the infraspinatus muscle was higher in association with B-type glenoids than in association with A-type glenoids on both the initial (14% versus 7%; p < 0.001) and the final follow-up (16% versus 10%; p = 0.003) CT scans.Conclusions: Asymmetric bone loss rarely develops in A1 glenoids, whereas initial posterior translation of the humeral head (B1 glenoids) may be associated with subsequent development and progression of posterior glenoid bone loss over time. Differences in fatty infiltration of the posterior aspect of the rotator cuff were seen between A-type and B-type glenoids, but the clinical relevance of this finding is currently unknown.Level Of Evidence: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence. [ABSTRACT FROM AUTHOR]

Background: Osteoarthritis of the glenohumeral joint has typical patterns of deformity as described by Walch et al. However, more severe glenoid pathology may be difficult to classify. The purpose of this study was to use 3-dimensional computed tomography (3-D CT) imaging analysis to define common pathologic subtypes that can be differentiated from the current Walch classification.Methods: We performed quantitative measurements of premorbid and pathologic anatomy using preoperative 3-D CT scans from 155 cases of advanced glenohumeral osteoarthritis that underwent anatomic or reverse total shoulder arthroplasty. We defined premorbid glenohumeral anatomy on the basis of previously validated methods using 3-D glenoid vault and humeral best-fit circle models including the premorbid glenoid version, joint-line medialization, and humeral-glenoid alignment (HGA). We determined the anatomic features that differentiate new glenoid morphologic subtypes from the existing Walch classification both qualitatively and quantitatively.Results: We defined 2 new glenoid subtypes (B3 and C2) for which the glenoid pathology and humeral alignment were not defined in the original Walch classification. The B3 glenoid has high pathologic retroversion, normal premorbid version, and acquired central and posterior bone loss that, on average, is greater than that of the B2 glenoid. The C2 glenoid is dysplastic with high pathologic retroversion, high premorbid version, and acquired posterior bone loss, giving it the appearance of a biconcave glenoid with posterior translation of the humeral head. This C2 glenoid can be confused with the B2 glenoid.Conclusions: The B3 and C2 patterns have qualitative and quantitative differences that may result in different clinical outcomes than classic B2 or C types; therefore, our findings suggest that these new subtypes should be included in a new or modified classification system. [ABSTRACT FROM AUTHOR]

Background: Glenoid bone loss associated with advanced glenohumeral arthritis is frequently accompanied by subluxation of the humeral head with subsequent inferior outcomes of shoulder arthroplasty. We hypothesized that the relationship between the center of the humeral head and the perpendicular to the glenoid fossa plane differs from, and is independent of, the relationship between the center of the humeral head and the plane of the scapula. Methods: Three-dimensional computed tomography (3D CT) imaging was performed on sixty patients with advanced osteoarthritis and fifteen controls with no osteoarthritis to define the baseline relationship between the center of the humeral head and the perpendicular to the glenoid fossa plane and the plane of the scapula. Correlations between these variables and the amount of bone loss and glenoid version were assessed. Results: There was a strong linear relationship (p < 0.001) between glenoid retroversion and the center of the humeral head in relation to the center line of the scapula (humeral-scapular alignment). Humeral head alignment in relation to the glenoid plane (humeral-glenoid alignment) was variable and not strongly correlated with the amount of glenoid retroversion. The average glenoid retroversion for the normal shoulders was -3.5°, and the average humeral-scapular alignment offset percentage was -2.3%. The average humeral-glenoid alignment offset for the normal shoulders was 0.5 mm with an average humeral-glenoid alignment offset percentage of 0.9%. Conclusions: The location of the humeral head in relation to the glenoid can be defined as displacement from the plane of the scapula and from the perpendicular of the glenoid plane. These two measures are independent of one another. The data suggest that each measurement may represent a different effect on glenoid loading. [ABSTRACT FROM AUTHOR]

Background: Restoration of native, premorbid glenoid anatomy may be a goal in component placement during total shoulder arthroplasty. However, if patients with unilateral glenohumeral osteoarthritis are predisposed to the development of arthritis owing to abnormal native glenoid anatomy, this recommendation may be inappropriate. Questions/purposes: The purpose of this study was to determine if patients with glenohumeral osteoarthritis have abnormal premorbid glenoid version or inclination, thereby predisposing them to subsequent glenoid disorders. We specifically tested whether: (1) premorbid glenoid version or inclination in the pathologic shoulder of patients with unilateral osteoarthritis, as determined by the glenoid vault model, is different from glenoid version or inclination in the contralateral nonpathologic shoulder of these patients; (2) there are differences between glenoid version or inclination in normal cadaver shoulders and the nonpathologic side of patients with unilateral osteoarthritis; and (3) there are differences between glenoid version or inclination in normal cadaver shoulders and the premorbid glenoid version and inclination in the pathologic shoulder of patients with unilateral osteoarthritis, as determined by the glenoid vault model. Methods: Bilateral CT scans were obtained in 27 patients with unilateral glenohumeral osteoarthritis. Thirty normal cadaver control shoulders also underwent CT scans. Premorbid glenoid version and inclination in the pathologic shoulder, as measured by the glenoid vault model, were compared with the contralateral nonpathologic shoulder and the normal cadaver control shoulders. Glenoid version and inclination of the normal shoulders were compared with the nonpathologic side from patients with unilateral osteoarthritis. Measurements were made by two different methods using three-dimensional surgical simulation software: (1) a direct measurement technique and (2) measurements derived from placement of a glenoid vault model. Mean differences in these parameters were compared between shoulder groups using paired and unpaired Student's t-tests. Results: Premorbid glenoid version and inclination in the pathologic shoulder as measured by the vault model averaged −7° (SD, 5) and 10° (SD, 6), respectively, compared with −7° (SD, 5) and 12° (SD, 6) as directly measured on the nonpathologic side, and −7° (SD, 4) and 12° (SD, 5) as directly measured in the normal cadaver control shoulders. There were no differences in glenoid version or inclination between the normal shoulders and the nonpathologic side of patients with unilateral osteoarthritis or between these shoulders and the premorbid version and inclination of the arthritic shoulder as measured by the vault model. Conclusions: Patients with glenohumeral osteoarthritis do not appear to have abnormal premorbid glenoid retroversion or inclination. The glenoid vault model can be used to determine premorbid glenoid version and inclination. Clinical Relevance: The glenoid vault model may be a clinically useful tool to estimate patient-specific premorbid glenoid anatomy, which may help in preoperative or intraoperative surgical planning for total shoulder arthroplasty. Level of Evidence: Level III, prognostic study. See Guidelines for Authors for a complete description of levels of evidence. [ABSTRACT FROM AUTHOR]

Background: Glenohumeral osteoarthritis may be associated with severe posterior glenoid bone loss and glenoid retroversion. Treatment with total shoulder arthroplasty and autologous bone graft obtained from the humeral head has been infrequently reported in the peer-reviewed literature. Methods: The clinical and radiographic results of primary total shoulder replacement with an all-polyethylene glenoid component and autologous humeral head graft augmentation performed by a single surgeon in thirteen consecutive patients were evaluated. Results: Twelve of the thirteen patients were followed for a minimum of two years (average, fifty-three months; range, twenty-six to 110 months). The average glenoid retroversion on preoperative computed tomography (CT) scans was 44° (range, 20° to 65°). Based on the Walch classification of pathologic glenoid morphology, nine glenoids were B2 and three were type C. All patients had an intact cuff at the time of surgery. At the time of the last follow up, ten of the twelve patients had graft incorporation without any resorbtion and two had minor bone graft resorption. Broken screws occurred in two of these ten cases. Two patients, both of whom required revision surgery, had failure of fixation and of graft incorporation; one of these failures was due to early postoperative trauma and the other, to Propionibacterium acnes infection. Conclusions: The early and midterm results of total shoulder arthroplasty with autogenous bone graft demonstrated substantial clinical and radiographic improvement in most cases. Level of Evidence: Therapeutic Leve IV. See Instructions for Authors for a complete description of levels of evidence. [ABSTRACT FROM AUTHOR]