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141 results on '"ZHANG Weihua"'

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1. Genome-wide characterization of circulating metabolic biomarkers.

2. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

3. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.

4. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.

5. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.

6. Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.

7. The power of genetic diversity in genome-wide association studies of lipids.

8. DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures.

9. Genome-wide association study identifies HLA-DR variants conferring risk of HBV-related acute-on-chronic liver failure.

10. A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.

11. Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.

12. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

13. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

14. Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.

15. Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

16. Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

17. Genome-wide association reveals that common genetic variation in the kallikrein-kinin system is associated with serum L-arginine levels.

18. Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.

19. 52 Genetic Loci Influencing Myocardial Mass.

20. Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

21. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.

22. A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

23. A coherent approach for analysis of the Illumina HumanMethylation450 BeadChip improves data quality and performance in epigenome-wide association studies.

24. Genetic studies of body mass index yield new insights for obesity biology.

25. New genetic loci link adipose and insulin biology to body fat distribution.

26. Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies.

27. Large-scale association analysis identifies new risk loci for coronary artery disease.

28. Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.

29. Seventy-five genetic loci influencing the human red blood cell.

30. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

31. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

32. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

33. Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.

34. Biological, clinical and population relevance of 95 loci for blood lipids.

35. Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.

36. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels.

37. Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians.

38. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

39. Genetic insights into resting heart rate and its role in cardiovascular disease.

40. Identification of type 2 diabetes loci in 433,540 East Asian individuals

41. Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

42. Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

43. Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

44. Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

45. Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

46. KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

47. Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

48. Defining the role of common variation in the genomic and biological architecture of adult human height

49. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

50. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

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