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Your search keyword '"Wang, Chuanhong"' showing total 2 results
Start Over Author "Wang, Chuanhong" Topic genome-wide association study
2 results on '"Wang, Chuanhong"'

1. Linkage mapping combined with GWAS revealed the genetic structural relationship and candidate genes of maize flowering time-related traits.

Author

Shi J, Wang Y, Wang C, Wang L, Zeng W, Han G, Qiu C, Wang T, Tao Z, Wang K, Huang S, Yu S, Wang W, Chen H, Chen C, He C, Wang H, Zhu P, Hu Y, Zhang X, Xie C, Lu X, and Li P

Subjects
Chromosome Mapping methods, Genetic Linkage, Phenotype, Plant Breeding, Polymorphism, Single Nucleotide genetics, Quantitative Trait Loci genetics, Genome-Wide Association Study methods, Zea mays genetics
Abstract

Background: Flowering time is an important agronomic trait of crops and significantly affects plant adaptation and seed production. Flowering time varies greatly among maize (Zea mays) inbred lines, but the genetic basis of this variation is not well understood. Here, we report the comprehensive genetic architecture of six flowering time-related traits using a recombinant inbred line (RIL) population obtained from a cross between two maize genotypes, B73 and Abe2, and combined with genome-wide association studies to identify candidate genes that affect flowering time., Results: Our results indicate that these six traits showed extensive phenotypic variation and high heritability in the RIL population. The flowering time of this RIL population showed little correlation with the leaf number under different environmental conditions. A genetic linkage map was constructed by 10,114 polymorphic markers covering the whole maize genome, which was applied to QTL mapping for these traits, and identified a total of 82 QTLs that contain 13 flowering genes. Furthermore, a combined genome-wide association study and linkage mapping analysis revealed 17 new candidate genes associated with flowering time., Conclusions: In the present study, by using genetic mapping and GWAS approaches with the RIL population, we revealed a list of genomic regions and candidate genes that were significantly associated with flowering time. This work provides an important resource for the breeding of flowering time traits in maize., (© 2022. The Author(s).)

Published
2022
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2. Molecular variation in a functionally divergent homolog of FCA regulates flowering time in Arabidopsis thaliana

Author

Hui Wang, Jian Shi, Peijin Li, Yan Zhang, Yunhe Wang, Shamsur Rehman, Tao Zhen, Wanyi Wang, Chunhong Qiu, Wang Chuanhong, and Daniele L. Filiault

Subjects
0106 biological sciences, 0301 basic medicine, Plant genetics, Science, Arabidopsis, General Physics and Astronomy, MADS Domain Proteins, Flowers, Protein degradation, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Gene Expression Regulation, Plant, Gene Duplication, Gene duplication, Arabidopsis thaliana, lcsh:Science, Gene, Genetics, Regulation of gene expression, Multidisciplinary, Polymorphism, Genetic, biology, Arabidopsis Proteins, Protein Stability, food and beverages, Plant morphogenesis, RNA-Binding Proteins, General Chemistry, biology.organism_classification, Cullin Proteins, Plants, Genetically Modified, Phenotype, Adaptation, Physiological, Chromatin, Phylogeography, 030104 developmental biology, Natural variation in plants, CUL1, lcsh:Q, 010606 plant biology & botany, Genome-Wide Association Study
Abstract

The identification and functional characterization of natural variants in plants are essential for understanding phenotypic adaptation. Here we identify a molecular variation in At2g47310 that contributes to the natural variation in flowering time in Arabidopsis thaliana accessions. This gene, which we term SISTER of FCA (SSF), functions in an antagonistic manner to its close homolog FCA. Genome-wide association analysis screens two major haplotypes of SSF associated with the natural variation in FLC expression, and a single polymorphism, SSF-N414D, is identified as a main contributor. The SSF414N protein variant interacts more strongly with CUL1, a component of the E3 ubiquitination complex, than the SSF414D form, mediating differences in SSF protein degradation and FLC expression. FCA and SSF appear to have arisen through gene duplication after dicot-monocot divergence, with the SSF-N414D polymorphism emerging relatively recently within A. thaliana. This work provides a good example for deciphering the functional importance of natural polymorphisms in different organisms., Natural variation represents valuable source for gene discovery. Here, the authors show that a homolog of Flowering Control Locus A (FCA) functions in an antagonistic manner to FCA in regulating Arabidopsis flowering time through interacting with CUL1-E3 and modulating FLC expression.

Published
2020

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